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1. 发明申请

US20070225564A1 Medical devices with local drug delivery capabilities 有权
标题翻译：具有局部药物输送能力的医疗器械
公开(公告)号：US20070225564A1
公开(公告)日：2007-09-27
申请号：US11390401
申请日：2006-03-27
申请人： Lucien Couvillon , Michael Banik , (Samuel) Zhong
发明人： Lucien Couvillon , Michael Banik , (Samuel) Zhong
IPC分类号： A61B1/00
CPC分类号： A61B1/012 , A61B1/2736 , A61B1/31 , A61B5/4839 , A61M2025/0057 , A61N1/306
摘要： A medical device, for example, an endoscope or catheter, includes local drug delivery capabilities for selectively delivering at least one drug in vivo. The local drug delivery may occur as the medical device is advanced through tortuous passageways of the patient's body or may occur after the medical device has reached its targeted destination. The medical device includes a drug agent, for example, carried in or on a hydrophilic or hydrogel coating disposed on the outside thereof. When the hydrogel or drug agent receives an appropriate signal, e.g., solution containing a triggering agent or triggering condition, e.g., heat or light, the hydrogel contracts or expands to squeeze out the drug from hydrogel. If electric current is provided as the signal, and the drug agent is charged, the drug agent is released by electrophoretic forces.
摘要翻译：医疗装置，例如内窥镜或导管，包括用于在体内选择性递送至少一种药物的局部药物递送能力。当医疗设备通过患者身体的曲折通道前进时，可能发生局部药物递送，或者可能在医疗设备到达目的地之后发生。医疗装置包括例如携带在设置在其外侧的亲水或水凝胶涂层中的药剂。当水凝胶或药剂接收适当的信号，例如含有引发剂或触发条件（例如热或轻）的溶液时，水凝胶收缩或膨胀以从水凝胶中挤出药物。如果提供电流作为信号，并且药剂被充电，则药物通过电泳力释放。

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