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1. 发明授权

US5586168A Apparatus incorporating a cellular telephone 失效
标题翻译：装有蜂窝电话的装置
公开(公告)号：US5586168A
公开(公告)日：1996-12-17
申请号：US318127
申请日：1994-10-05
申请人： Brian D. Bucalo , Louis R. Bucalo , Peter M. Kash
发明人： Brian D. Bucalo , Louis R. Bucalo , Peter M. Kash
IPC分类号： A45C15/00 , H04B1/38 , H04M1/02 , H04Q7/32
CPC分类号： H04B1/3888 , A45C15/00 , H04B1/3827 , H04M1/02
摘要： Cellular telephone apparatus having at least two pieces that are separated or separable such that the cellular antenna may be situated at a distance from the user during use. The cellular telephone apparatus has a cellular antenna which communicates with the user microphone and speaker via either a cordless phone type radio link or a cord. High frequency, electromagnetic radiation emitted from the cellular antenna is thereby substantially diminished by the time it reaches the phone user. The apparatus may include a portable carrying case, such as a conventional attache case to provide the utility of a business briefcase, a cellular telephone base unit situated within an interior space of the carrying case, a cellular antenna coupled to the base unit, a dial pad arranged on an exterior wall of the carrying case, and either a speaker phone unit arranged on the exterior wall of the carrying case, a communications unit coupled to the base unit so that the communications unit is positionable during use at a position away from the cellular antenna which is situated at the carrying case. The communications unit may be either a handset/microphone unit or a headset/microphone unit.
摘要翻译：具有分离或分离的至少两个片段的蜂窝电话设备，使得在使用期间蜂窝天线可能位于距离用户一定距离处。蜂窝电话设备具有通过无绳电话型无线电链路或线路与用户麦克风和扬声器通信的蜂窝天线。从蜂窝式天线发射的高频，电磁辐射在到达电话用户的时间基本上减弱。该装置可以包括便携式手提箱，例如常规的附件盒，以提供商业公文包的实用性，位于便携箱的内部空间内的蜂窝电话基座单元，耦合到基座单元的蜂窝天线，拨号盘布置在便携箱的外壁上的扬声器电话单元和布置在便携箱的外壁上的扬声器电话单元，连接到基座单元的通信单元，使得通信单元在使用期间可以在远离位于手提箱的蜂窝天线。通信单元可以是手机/麦克风单元或耳机/麦克风单元。

2. 发明授权

US5444778A Apparatus incorporating a cellular telephone 失效
标题翻译：装有蜂窝电话的装置
公开(公告)号：US5444778A
公开(公告)日：1995-08-22
申请号：US83062
申请日：1993-06-25
申请人： Louis R. Bucalo , Brian D. Bucalo , Peter M. Kash
发明人： Louis R. Bucalo , Brian D. Bucalo , Peter M. Kash
IPC分类号： A45C15/00 , H04B1/38 , H04M1/02 , H04M1/00
CPC分类号： A45C15/00 , H04B1/3827 , H04B1/3888 , H04M1/02
摘要： Cellular telephone apparatus comprise a portable carrying case, such as a conventional attache case to provide the utility of a business briefcase, a cellular telephone base unit situated within an interior space of the carrying case, an antenna coupled to the base unit, a hand-held receiver, and either a cable or radio link coupling the base unit and hand-held receiver with each other so that the receiver is positionable during use at a position which is spaced away from the antenna which is situated at the carrying case. High frequency, electromagnetic radiation emitted from the antenna is substantially attenuated by the time it reaches the user of the cellular telephone.
摘要翻译：蜂窝电话设备包括便携式携带箱，例如传统的附属箱，以提供商业公文包的用途，位于便携箱的内部空间内的蜂窝电话基座单元，耦合到基座单元的天线，以及将基座单元和手持式接收器彼此连接的电缆或无线电链路，使得接收器在使用期间可以位于与位于便携箱处的天线间隔开的位置。从天线发射的高频，电磁辐射在达到蜂窝电话用户的时间内被大大衰减。

3. 发明授权

US5857981A Biopsy instrument with tissue specimen retaining and retrieval device 失效
标题翻译：活组织检查仪器具有组织标本保留和检索装置
公开(公告)号：US5857981A
公开(公告)日：1999-01-12
申请号：US527257
申请日：1995-09-12
申请人： Brian D. Bucalo , Louis R. Bucalo
发明人： Brian D. Bucalo , Louis R. Bucalo
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00
CPC分类号： A61B10/0266 , A61B2017/00433
摘要： A biopsy instrument including a tissue penetrating device including an elongate holder and a cutting member arranged at an end thereof for penetrating tissue and a specimen retaining and retrieval device detachably connected to the holder for receiving and retaining a specimen of tissue cut by the cutting member. The specimen retaining and retrieval device preferably has a handle having a contoured, outer surface substantially corresponding to the shape of a thumb and which is roughened. Also, preferably the tissue penetrating device includes a hand grip section arranged at an end of the holder opposite to the end at which the cutting member is arranged and a middle section arranged between the hand grip section and the cutting member, the middle section being substantially cylindrical and having friction grip enhancing means, i.e., grooves arranged on an outer peripheral surface in a direction substantially perpendicular to the longitudinal direction of the tissue penetrating device.
摘要翻译：一种活检器械，包括组织穿透装置，其包括细长保持器和布置在其端部处的用于穿透组织的切割构件和可拆卸地连接到保持器的样本保持和取出装置，用于接收和保持由切割构件切割的组织样本。样品保持和取出装置优选地具有手柄，其具有基本上对应于拇指的形状并且被粗糙化的轮廓外表面。此外，优选组织穿透装置包括手柄部，其设置在与保持切割部件的端部相对的保持器的端部处，以及设置在手柄部分和切割部件之间的中间部分，中间部分基本上具有摩擦夹持增强装置，即，在基本上垂直于组织穿透装置的纵向方向的方向上布置在外周表面上的凹槽。

4. 发明授权

US5786752A Emergency signal system for vehicles 失效
标题翻译：车辆应急信号系统
公开(公告)号：US5786752A
公开(公告)日：1998-07-28
申请号：US678957
申请日：1996-07-12
申请人： Louis R. Bucalo , Brian D. Bucalo
发明人： Louis R. Bucalo , Brian D. Bucalo
IPC分类号： B60Q1/52 , B60Q1/50
CPC分类号： B60Q1/52
摘要： A vehicle signaling method and device for alerting drivers approaching from a rear of the vehicle including at least one light emitting signal arranged on an element of the vehicle facing rearward, a velocity measurement sensor for measuring an absolute velocity of the vehicle and a control unit coupled to the velocity measurement sensor for determining if the measured absolute velocity is greater than a threshold velocity. In one embodiment, there is a manual light activation unit which is connected to the control unit and the light emitting signal(s). The manual light activation unit is controlled by the control unit to enable the light emitting signal(s) to be activated only if the measured absolute velocity is less than the threshold velocity. In another embodiment, which can be used separate from or together with the velocity control unit, the device includes a deceleration measurement sensor coupled to the velocity threshold measurement sensor for measuring deceleration of the vehicle and which are activated by the control unit only if the measured absolute velocity is greater than a threshold velocity. A deceleration threshold determining unit then determines if the measured deceleration is greater than a threshold deceleration and the light emitting signal(s) is activated if the absolute velocity is greater than the threshold velocity as determined by the control unit and the measured deceleration is greater than the deceleration threshold as measured by the deceleration threshold determining unit.
摘要翻译：一种用于警告从车辆后方接近的驾驶员的车辆信令方法和装置，包括布置在面向后方的车辆的元件上的至少一个发光信号，用于测量车辆的绝对速度的速度测量传感器和耦合的控制单元到速度测量传感器，用于确定所测量的绝对速度是否大于阈值速度。在一个实施例中，存在连接到控制单元和发光信号的手动光激活单元。手动光激活单元由控制单元控制，以使发光信号仅在所测量的绝对速度小于阈值速度时被激活。在可与速度控制单元分开使用或与速度控制单元一起使用的另一个实施例中，该装置包括耦合到速度阈值测量传感器的减速测量传感器，用于测量车辆的减速度，并且仅当所测量的绝对速度大于阈值速度。然后，减速阈值确定单元确定所测量的减速度是否大于阈值减速度，并且如果绝对速度大于由控制单元确定的阈值速度并且所测量的减速度大于阈值速度，则发光信号被激活由减速阈值确定单元测量的减速阈值。

5. 发明授权

US06210664B1 Method for gene transfer to the central nervous system 失效
标题翻译：基因转移到中枢神经系统的方法
公开(公告)号：US06210664B1
公开(公告)日：2001-04-03
申请号：US08629308
申请日：1996-04-08
申请人： Bruce Cherksey , Louis R. Bucalo
发明人： Bruce Cherksey , Louis R. Bucalo
IPC分类号： A01N6300
CPC分类号： A61K48/0075 , A61K48/00 , A61K2121/00 , C12N2510/02
摘要： The present invention relates to a method for implanting producer cells into the mammalian brain. The producer cells are engineered with a retroviral based recombinant vector encoding a tumorcidal factor or susceptibility factor that confers on tumor cells sensitivity to chemotherapeutic or radiotherapeutic agents. Prior to transplantation into the mammalian brain, the producer cells are first cultured in vitro on a support matrix to increase the long-term viability of the transplanted cells and to provide long-term functional benefit.
摘要翻译：本发明涉及将生产细胞植入哺乳动物脑中的方法。使用基于逆转录病毒的重组载体来编码生产细胞，该重组载体编码赋予肿瘤细胞对化学治疗剂或放射治疗剂敏感性的杀肿瘤因子或易感性因子。在移植到哺乳动物脑中之前，首先在支持基质上体外培养生产细胞以增加移植细胞的长期活力并提供长期的功能益处。

6. 发明授权

US08277342B2 Modified soccer game 失效
标题翻译：修改足球比赛
公开(公告)号：US08277342B2
公开(公告)日：2012-10-02
申请号：US12944164
申请日：2010-11-11
申请人： Louis R. Bucalo
发明人： Louis R. Bucalo
IPC分类号： A63B67/18 , A63B69/00
CPC分类号： A63B67/002 , A63B2243/0025 , A63C19/02
摘要： A modified soccer (“football”) field layout and associated modified method of playing soccer on the modified soccer field layout are described. The modified soccer field layout is approximately the same size as a conventional soccer field layout. In one example, the modified soccer field layout also has two Forward Areas and two Forward Lines. In one example, the method of playing soccer on the modified soccer field includes at least one associated Forward Area Soccer Rule.
摘要翻译：描述了改进的足球（足球）场布局和相关的修改的在改进的足球场布局上踢足球的方法。改进的足球场布局与常规足球场布局大致相同。在一个例子中，修改后的足球场布局也有两个前向区域和两条前向线路。在一个示例中，在修改的足球场上踢足球的方法包括至少一个相关的前区足球规则。

7. 发明申请

US20100304343A1 Method and Apparatus for Language Instruction 审中-公开
标题翻译：语言教学方法与装置
公开(公告)号：US20100304343A1
公开(公告)日：2010-12-02
申请号：US12792143
申请日：2010-06-02
申请人： Louis R. Bucalo
发明人： Louis R. Bucalo
IPC分类号： G09B19/06 , G09B19/04
CPC分类号： G09B5/065
摘要： A system is provided for acquiring increased proficiency in a new or target language by enabling frequent repeated hearing and mimicking of discrete audio sound bites in the target language, wherein the sound bites and their frequency of repetition may be easily selected by the user before or during use. The sound bites may be played singly or in sequential groups or user defined groups, and automatically repeated as necessary or desired to achieve audio imprinting of the sound bites by simply listening and repeating the sounds without substantial intellectual effort or attempts at memorization. The system enables user selected or sequential hearing and mimicking of specific sound bites or groups of sound bites repeatedly in each use session in the context of meaning, without requiring dedicated language learning time, and thereby helps reproduce the natural process of initial native language acquisition which occurs without substantial intellectual effort and memorization.
摘要翻译：提供了一种用于通过使得能够频繁地反复听到并模仿目标语言中的离散音频声音叮咬来获得增加的新语言或目标语言熟练度的系统，其中声音位和它们的重复频率可以在用户之前或期间容易地被选择使用。声音可以单独播放或以连续的组或用户定义的组播放，并且如果必要或需要自动重复，以通过简单地收听和重复声音而无需大量的智力或尝试记忆来实现声音叮咬的音频打印。该系统使得用户在意图的上下文中可以在每个使用会话中重复地选择或连续地听到并模仿特定的声音咬合或声音组，而不需要专门的语言学习时间，从而有助于再现初始母语习得的自然过程，在没有实质的智力和记忆的情况下发生。

8. 发明授权

US08852623B2 Implantable polymeric device for sustained release of dopamine agonist 有权
标题翻译：用于持续释放多巴胺激动剂的可植入聚合物
公开(公告)号：US08852623B2
公开(公告)日：2014-10-07
申请号：US13525193
申请日：2012-06-15
申请人： Rajesh A. Patel , Louis R. Bucalo , Lauren Costantini , Sofie Kleppner
发明人： Rajesh A. Patel , Louis R. Bucalo , Lauren Costantini , Sofie Kleppner
IPC分类号： A61K9/00 , A61K31/48 , A61K9/16 , A61L31/16 , A61K31/485 , A61K31/381 , A61K31/428 , A61K31/4045 , A61K9/14 , A61L31/04
CPC分类号： A61L31/16 , A61K9/0024 , A61K9/146 , A61K9/1635 , A61K31/198 , A61K31/381 , A61K31/4045 , A61K31/428 , A61K31/48 , A61K31/485 , A61L31/048 , A61L31/10 , A61L31/125 , A61L31/146 , A61L2300/20 , A61L2300/40 , A61L2300/41 , A61L2300/602 , A61L2300/606 , A61L2300/62 , A61L2420/04 , C08L31/04
摘要： The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases dopamine agonist continuously with generally linear release kinetics for extended periods of time. Dopamine agonist is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with dopamine agonist.
摘要翻译：本发明提供了用于治疗帕金森病的组合物，方法和试剂盒以及用多巴胺激动剂治疗是治疗有益的其它病症。本发明提供了一种生物相容的非可溶性聚合物装置，其可延长释放动力学持续释放多巴胺激动剂。多巴胺激动剂通过对其被包封的聚合物基质的表面开放的孔释放。该装置可以皮下给予需要用多巴胺激动剂连续治疗的个体。

9. 发明申请

US20110059819A1 MODIFIED SOCCER GAME USING FORWARD LINES 失效
标题翻译：使用前进线的改装的足球游戏
公开(公告)号：US20110059819A1
公开(公告)日：2011-03-10
申请号：US12944164
申请日：2010-11-11
申请人： Louis R. Bucalo
发明人： Louis R. Bucalo
IPC分类号： A63C19/00
CPC分类号： A63B67/002 , A63B2243/0025 , A63C19/02
摘要： A modified soccer (“football”) field layout and associated modified method of playing soccer on the modified soccer field layout are described. The modified soccer field layout is approximately the same size as a conventional soccer field layout. In one example, the modified soccer field layout also has two Forward Areas and two Forward Lines. In one example, the method of playing soccer on the modified soccer field includes at least one associated Forward Area Soccer Rule.
摘要翻译：描述了修改后的足球场（“足球”）场布局和相关修改的在改装的足球场布局上踢足球的方法。改进的足球场布局与常规足球场布局大致相同。在一个例子中，修改后的足球场布局也有两个前向区域和两条前向线路。在一个示例中，在修改的足球场上踢足球的方法包括至少一个相关的前区足球规则。

10. 发明申请

US20080311171A1 IMPLANTABLE POLYMERIC DEVICE FOR SUSTAINED RELEASE OF DOPAMINE AGONIST 审中-公开
标题翻译：用于持续释放多巴胺激动剂的可植入聚合物
公开(公告)号：US20080311171A1
公开(公告)日：2008-12-18
申请号：US12119334
申请日：2008-05-12
申请人： Rajesh A. PATEL , Louis R. Bucalo , Lauren Costantini , Sofie Kleppner
发明人： Rajesh A. PATEL , Louis R. Bucalo , Lauren Costantini , Sofie Kleppner
IPC分类号： A61K9/00 , A61K31/435 , A61K31/437 , A61K31/56 , A61P29/00 , A61P25/16
CPC分类号： A61L31/16 , A61K9/0024 , A61K9/146 , A61K9/1635 , A61K31/198 , A61K31/381 , A61K31/4045 , A61K31/428 , A61K31/48 , A61K31/485 , A61L31/048 , A61L31/10 , A61L31/125 , A61L31/146 , A61L2300/20 , A61L2300/40 , A61L2300/41 , A61L2300/602 , A61L2300/606 , A61L2300/62 , A61L2420/04 , C08L31/04
摘要： The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases dopamine agonist continuously with generally linear release kinetics for extended periods of time. Dopamine agonist is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with dopamine agonist.
摘要翻译：本发明提供了用于治疗帕金森病的组合物，方法和试剂盒以及用多巴胺激动剂治疗是治疗有益的其它病症。本发明提供了一种生物相容的非可溶性聚合物装置，其可延长释放动力学持续释放多巴胺激动剂。多巴胺激动剂通过对其被包封的聚合物基质的表面开放的孔释放。该装置可以皮下给予需要用多巴胺激动剂连续治疗的个体。

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