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1. 发明申请

US20090118316A1 Methods for Augmenting Bone 审中-公开
标题翻译：增强骨的方法
公开(公告)号：US20090118316A1
公开(公告)日：2009-05-07
申请号：US11570815
申请日：2005-06-10
申请人： Lisa M. Olson , Thomas A. Brown , Leonard Buckbinder , Angel Guzman-Perez , John C. Kath , Hua Zhu Ke , Michael J. Luzzio
发明人： Lisa M. Olson , Thomas A. Brown , Leonard Buckbinder , Angel Guzman-Perez , John C. Kath , Hua Zhu Ke , Michael J. Luzzio
IPC分类号： A61K31/506 , A61K31/405 , A61K31/40
CPC分类号： A61K31/506 , A61K31/00
摘要： The present invention relates to methods of stimulating osteoblast function with a PYK2 inhibitor in subjects with osteoporosis, bone fractures, non-unions, pseudoarthroses, periodontal disease or other disorders of bone metabolism. Optionally, the method further comprises administration of a second therapeutic bone agent. The present invention also relates to methods to identify a PYK2 inhibitor effective as a therapeutic bone agent comprising administering a test agent to an osteoblast-like cell and determining if osteoblast function is stimulated. Optionally, the identifying method further comprises contacting the test agent with PYK2 and determining if PYK2 activity is inhibited.
摘要翻译：本发明涉及在具有骨质疏松症，骨折，非联合，假性关节炎，牙周病或其他骨代谢紊乱的受试者中用PYK2抑制剂刺激成骨细胞功能的方法。任选地，所述方法还包括施用第二治疗骨剂。本发明还涉及鉴定有效作为治疗性骨质的PYK2抑制剂的方法，其包括向成骨细胞样细胞施用测试试剂并确定是否刺激成骨细胞功能。任选地，识别方法还包括使测试试剂与PYK2接触并确定PYK2活性是否被抑制。

2. 发明申请

US20130315131A1 Method and System For Coordinating Access To A Barrage Relay Network 有权
标题翻译：协调拦截中继网络的方法和系统
公开(公告)号：US20130315131A1
公开(公告)日：2013-11-28
申请号：US13480387
申请日：2012-05-24
申请人： Thomas A. Brown , Thomas R. Halford , Mark L. Johnson
发明人： Thomas A. Brown , Thomas R. Halford , Mark L. Johnson
IPC分类号： H04W74/00 , H04B7/14 , H04J3/00
CPC分类号： H04L47/15 , H04L45/32 , H04L47/14 , H04L47/28 , H04L47/32 , H04W74/00 , H04W84/047
摘要： Methods for coordinating access to a barrage relay networks are disclosed. For example, one disclosed method includes: receiving, by a first node, a first message from a second node on a network; suppressing transmission of messages by the first node; receiving, by the first node, a second message corresponding to the first message or waiting a sufficient amount of time without receipt of the second message; reactivating transmission of the messages by the first node.
摘要翻译：公开了用于协调对拦阻中继网络的访问的方法。例如，一种公开的方法包括：由第一节点从网络上的第二节点接收第一消息; 抑制第一节点的消息传输; 由所述第一节点接收与所述第一消息相对应的第二消息或者等待足够的时间而不接收到所述第二消息; 重新激活第一个节点的消息传输。

3. 发明申请

US20080302021A1 LOCK AND SEAL SYSTEM FOR SLIDING DOORS 有权
标题翻译：滑动门锁和密封系统
公开(公告)号：US20080302021A1
公开(公告)日：2008-12-11
申请号：US12135027
申请日：2008-06-06
申请人： Geoff Gosling , Mogens F. Smed , Thomas A. Brown , Steven M. van Beveren
发明人： Geoff Gosling , Mogens F. Smed , Thomas A. Brown , Steven M. van Beveren
IPC分类号： E06B7/16 , E05B65/08
CPC分类号： E05B65/0876 , E05C17/60 , E06B7/2309 , Y10S292/46 , Y10T70/519 , Y10T70/5195 , Y10T292/096 , Y10T292/1014 , Y10T292/68
摘要： Implementations of the present invention relate generally to systems and components for sealing and locking doors, including sliding doors for use with modular walls. A locking system can be configured to secure and release a sliding door. In particular, the locking system can include a sliding door with one or more receiving channels configured to receive a pin extending from a floor's surface. A locking mechanism can be included and configured to selectively drive a shaft to capture and release a pin that has been received by the receiving channel. The sealing system is configured to seal a gap between a modular wall and an adjacent sliding door. In particular, the sealing system can include a connector configured to connect trim to a wall panel wherein the connector includes an integrated gasket seal configured to seal the gap.
摘要翻译：本发明的实施方式一般涉及用于密封和锁定门的系统和组件，包括用于模块化墙的滑动门。锁定系统可以被配置为固定和释放滑动门。特别地，锁定系统可以包括具有一个或多个接收通道的滑动门，其被配置为接收从地板表面延伸的销。可以包括锁定机构并构造成选择性地驱动轴以捕获和释放由接收通道接收的销。密封系统构造成密封模块化壁与相邻滑动门之间的间隙。特别地，密封系统可以包括被配置为将装饰件连接到墙板的连接器，其中连接器包括构造成密封间隙的集成密封件密封件。

4. 发明申请

US20080198789A1 METHOD AND SYSTEM FOR ESTABLISHING COOPERATIVE ROUTING IN WIRELESS NETWORKS 有权
标题翻译：在无线网络中建立合作路由的方法和系统
公开(公告)号：US20080198789A1
公开(公告)日：2008-08-21
申请号：US12101633
申请日：2008-04-11
申请人： Thomas A. Brown , Adam M. Blair , Mark L. Johson , Thomas R. Halford
发明人： Thomas A. Brown , Adam M. Blair , Mark L. Johson , Thomas R. Halford
IPC分类号： H04B7/14 , H04L12/56
CPC分类号： H04W40/28 , H04B7/2606 , H04L45/10 , H04L45/122 , H04L45/22 , H04L45/24 , H04W16/26 , H04W40/22 , H04W76/12 , H04W84/18 , H04W88/04
摘要： A system and method is presented for establishing relayed communications involving (1) sending a request message from a source node to a destination node through a plurality of intermediate nodes, (2) receiving the request message at the destination node, and (3) sending an acceptance message from the destination node to the source node through at least a subset of the intermediate nodes, wherein an intermediate node relays the request or acceptance message by receiving the message and re-transmitting the message, and wherein the intermediate node is capable of receiving the message from more than one other intermediate node.
摘要翻译：提出了一种用于建立中继通信的系统和方法，涉及（1）通过多个中间节点从源节点向目的地节点发送请求消息，（2）在目的地节点处接收请求消息，以及（3）发送通过所述中间节点的至少一个子集从所述目的地节点到所述源节点的接受消息，其中中间节点通过接收所述消息并重新发送所述消息来中继所述请求或接受消息，并且其中所述中间节点能够从多个其他中间节点接收消息。

5. 外观设计

USD462890S1 Flexible cable manager 失效
标题翻译：柔性电缆管理器
公开(公告)号：USD462890S1
公开(公告)日：2002-09-17
申请号：US29143528
申请日：2001-06-15
申请人： Thomas A. Brown
设计人： Thomas A. Brown

6. 发明授权

US06289514B1 System and method for the near-real time capture and reporting of large population consumer behaviors concerning television use 有权
标题翻译：近距离捕获和报告电视用户大量消费者行为的系统和方法
公开(公告)号：US06289514B1
公开(公告)日：2001-09-11
申请号：US09280035
申请日：1999-03-29
申请人： John F. Link , George A. Graves , George Endler, III , Christopher J. Heimark , Thomas A. Brown
发明人： John F. Link , George A. Graves , George Endler, III , Christopher J. Heimark , Thomas A. Brown
IPC分类号： H04N716
CPC分类号： H04N7/17309 , H04H60/31 , H04N21/25891 , H04N21/44222 , H04N21/6582
摘要： A system and method for identifying television programming, identifying and capturing consumer behavior as regards such programming and providing a nearly-real time reporting of that information to interested parties, while also providing verification of actual delivery of advertising and/or program content.
摘要翻译：一种用于识别电视节目的系统和方法，识别和捕获关于这种节目的消费者行为，并且向感兴趣方提供该信息的几乎实时的报告，同时还提供对广告和/或节目内容的实际传送的验证。

7. 发明授权

US5594761A Control channel timing detection and self correction for digitally trunked simulcast radio communications system 失效
标题翻译：数字中继联播无线电通信系统的控制信道定时检测和自校正
公开(公告)号：US5594761A
公开(公告)日：1997-01-14
申请号：US253600
申请日：1994-06-03
申请人： Thomas A. Brown
发明人： Thomas A. Brown
IPC分类号： H04B7/26 , H04H20/67 , H04W24/00 , H04W56/00 , H04L7/00
CPC分类号： H04H20/67 , H04B7/2684 , H04W24/00 , H04W56/00
摘要： A control channel timing monitor for a simulcast radio frequency (RF) digitally trunked mobile radio communications system continually monitors the outbound control channel timing of each of plural simulcasting transmitting sites. The timing of such monitored signals obtained "over the air" is compared relative to one another and/or to a reference. Fault indications identifying specific sites having faulty synchronization are produced when such comparison indicates lack of synchronization within a programmable tolerance. Appropriate corrective action (e.g., bringing down the control channel and transferring its function to a frequency formerly used for working channel functions) is taken.
摘要翻译：用于联播射频（RF）数字集群移动无线电通信系统的控制信道定时监视器连续监视多个同时广播发送站点中的每一个的出站控制信道定时。 “空中”获得的这种监视信号的时序相对于彼此和/或参考进行比较。当这种比较表明在可编程公差内缺少同步时，会产生识别具有故障同步的特定站点的故障指示。采取适当的纠正措施（例如，降低控制信道并将其功能传送到以前用于工作信道功能的频率）。

8. 发明授权

US5131007A Digital voter for multiple site PST R trunking system 失效
标题翻译：多站点PST R中继系统的数字投票者
公开(公告)号：US5131007A
公开(公告)日：1992-07-14
申请号：US363980
申请日：1989-06-09
申请人： Thomas A. Brown , Charles L. Derenge , Marcella M. Tucker , Vicki J. Teel , Houston H. Hughes, III
发明人： Thomas A. Brown , Charles L. Derenge , Marcella M. Tucker , Vicki J. Teel , Houston H. Hughes, III
IPC分类号： H04B7/24 , H04M11/00 , H04W4/10 , H04W84/08
CPC分类号： H04W84/08 , H04W4/10 , H04W76/005
摘要： A digital voter system for a multi-site public service trunking (PST) digitally trunked RF communications system operates on the principle that it is highly likely that messages received during a system redundancy removal period are redundant messages. For a given RF channel, digital receiver is associated with each of multiple sites and receives digital messages reported to it by its associated sites. The multiple digital receivers are connected to a digital selector via a service request line (FSL) and a serial data line (BSL). Digital receivers which have messages to transfer to the digital selector attempt to seize the service request line and, if they successfully seize it, maintain the line in its seized state for the redundancy removal period. Digital receivers which have messages but discover the service request line is already seized simply discard their messages. Since it is likely that two digital receivers may successfully seize the service request line at or near the same time, a windowing technique is used to schedule the times different digital receivers may apply their messages to the serial data line. If a digital receiver sees signals on the serial data line before it is scheduled to begin transmitting, it discards its message and aborts its transmission attempt. The preferred embodiment voter thus handles messages very rapidly (to reduce system latency time) while effectively removing most redundant messages and reducing or eliminating data collision on the shared serial data bus.
摘要翻译：用于多站点公共服务中继（PST）数字集群RF通信系统的数字投票系统的操作原理是，在系统冗余删除期间接收的消息很可能是冗余消息。对于给定的RF信道，数字接收机与多个站点中的每一个相关联并且接收由其相关站点向其报告的数字消息。多个数字接收器通过服务请求线（FSL）和串行数据线（BSL）连接到数字选择器。具有传送到数字选择器的消息的数字接收机尝试占用服务请求线路，并且如果它们成功占用，则将该线路保持在占用状态以用于冗余消除周期。具有消息但发现服务请求行的数字接收器已经被占用，简单地丢弃其消息。由于两个数字接收机很可能在同一时间或接近同一时间成功地占用服务请求线，所以使用开窗技术调度不同的数字接收机将其消息应用于串行数据线的时间。如果数字接收机在计划开始发送之前看到串行数据线上的信号，则丢弃其消息并中止其发送尝试。因此，优选实施例的选择器非常快速地处理消息（以减少系统等待时间），同时有效地去除大多数冗余消息并减少或消除共享串行数据总线上的数据冲突。

9. 发明授权

US4471268A Lighting unit having power supply with improved switching means 失效
标题翻译：照明单元具有改进的开关装置的电源
公开(公告)号：US4471268A
公开(公告)日：1984-09-11
申请号：US452904
申请日：1982-12-27
申请人： Thomas A. Brown , Marc A. Dissosway , James E. Harris , William Peil
发明人： Thomas A. Brown , Marc A. Dissosway , James E. Harris , William Peil
IPC分类号： H05B41/18 , H05B41/36 , H05B35/00
CPC分类号： H05B41/36
摘要： An energy efficient lighting unit is described designed for functional similarity to the incandescent light used in the home. The lighting unit utilizes a metal vapor arc lamp as the main source of light supplemented by a standby filamentary light source. The lighting unit includes means for converting 60 hertz ac to dc, and a dc energized operating network containing a three transistor switch. The transistor switch is used to provide dc and low frequency (120 Hz) energization to the filament, and high frequency energization for both filament and arc lamp. The high frequency energization, which starts and transitions the arc lamp, is discontinued after the arc lamp is started. In the final run state, the arc lamp, which is serially connected with the filament across the dc supply, is ballasted by the filament. The transistor switch is controlled in its operation by an integrated circuit.
摘要翻译：描述了一种设计用于与家用白炽灯功能相似的节能照明单元。照明单元利用金属蒸气弧灯作为补充有备用丝状光源的主要光源。照明单元包括用于将60赫兹交流转换为直流的装置，以及包含三晶体管开关的直流通电工作网络。晶体管开关用于为灯丝提供直流和低频（120 Hz）通电，以及灯丝和弧光灯的高频通电。弧光灯启动后停止启动和转换弧光灯的高频通电。在最终的运行状态下，通过直流电源与灯丝串联连接的电弧灯被灯丝镇压。晶体管开关由集成电路控制在其工作状态。

10. 发明授权

US4392081A Lighting unit 失效
标题翻译：照明单元
公开(公告)号：US4392081A
公开(公告)日：1983-07-05
申请号：US288855
申请日：1981-07-31
申请人： Thomas A. Brown , William Peil
发明人： Thomas A. Brown , William Peil
IPC分类号： H01J61/56 , H01J61/96 , H05B35/00 , H05B41/24 , H02K17/34 , H02P1/54
CPC分类号： H01J61/96 , H01J61/56
摘要： A lighting unit is described utilizing an energy efficient metal vapor arc lamp as the main source of light supplemented by a standby filamentary light source producing light when the arc lamp is being started. The lighting unit is designed as a more efficient replacement for the incandescent lamp. The lighting unit includes means for conversion of 60 hertz ac to dc, and a dc energized operating network, including a ferrite transformer and an intermittently operated switching transistor serially connected with a load consisting of the filament or the arc lamp, or both, to which regulated output power is provided. The operating network produces an output with minimum dissipation adapted to each operating state of the arc lamp, including the provision of a high ignition potential, adequate power for the lamp during the glow to arc transition, warm-up and ballasting. In addition, while the arc lamp is being started, the operating network provides power for lighting the standby filament.
摘要翻译：使用能量有效的金属蒸汽弧光灯作为主要光源来描述照明单元，该电源补充有待弧光灯起动时产生光的备用丝光光源。照明单元被设计为更有效地替代白炽灯。照明单元包括用于将60赫兹交流转换为直流的装置，以及直流通电操作网络，包括铁氧体变压器和与由灯丝或弧光灯组成的负载串联连接的间歇操作的开关晶体管，或两者，其中提供调节输出功率。操作网络产生的输出具有适应于弧光灯的每个操作状态的最小耗散，包括提供高的点火电位，在发光到电弧转换，预热和压载期间灯的足够的功率。另外，当弧光灯正在启动时，操作网络提供用于照亮待机灯丝的电源。

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