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1. 发明申请

US20050049582A1 Method and apparatus for fractional photo therapy of skin 审中-公开
$Method and apparatus for fractional photo therapy of skin$
标题翻译：皮肤分光疗法的方法和装置
公开(公告)号：US20050049582A1
公开(公告)日：2005-03-03
申请号：US10888356
申请日：2004-07-09
申请人： Leonard DeBenedictis , G. Herron , Robert Sink , David Eimerl , Vladimir Lemberg , George Voevodkin , Michael Black
发明人： Leonard DeBenedictis , G. Herron , Robert Sink , David Eimerl , Vladimir Lemberg , George Voevodkin , Michael Black
IPC分类号： A61B5/00 , A61B17/00 , A61B18/20
CPC分类号： A61B18/20 , A61B18/203 , A61B2017/00057 , A61B2018/00452 , A61B2018/0047 , A61B2018/20351 , A61B2018/20359 , A61B2018/205545 , A61B2018/2075 , A61B2018/208
摘要： A method and apparatus for providing fractional treatment of tissue (e.g., skin) using lasers is disclosed. The method involves creating one or more microscopic treatment zones of necrotic tissue and thermally-altered tissue and intentionally leaving viable tissue to surround the microscopic treatment zones. The dermatological apparatus includes one or more light sources and a delivery system to generate the microscopic treatment zones in a predetermined pattern. The microscopic treatment zones may be confined to the epidermis, dermis or span the epidermal-dermal junction, and further the stratum corneum above the microscopic treatment zones may be spared.
摘要翻译：公开了一种使用激光提供对组织（例如皮肤）的分数次处理的方法和装置。该方法包括创建坏死组织和热改变组织的一个或多个微观治疗区域，并有意地留下活组织以包围微观治疗区域。皮肤病学装置包括一个或多个光源和用于以预定图案产生微观治疗区的递送系统。微观处理区域可能被限制在表皮，真皮层或跨越表皮 - 皮肤接合处，并且可以避免在微观处理区域上方的角质层。

2. 发明申请

US20050278002A1 Adaptive control of optical pulses for laser medicine 有权
标题翻译：激光医学光脉冲的自适应控制
公开(公告)号：US20050278002A1
公开(公告)日：2005-12-15
申请号：US10868134
申请日：2004-06-14
申请人： David Eimerl , Leonard DeBenedictis
发明人： David Eimerl , Leonard DeBenedictis
IPC分类号： A61B17/00 , A61B18/20 , A61N1/00
CPC分类号： A61B18/203 , A61B18/20 , A61B2017/00022 , A61B2017/00084 , A61B2018/00452 , A61B2018/00636 , A61B2018/20351
摘要： Tissue is treated by irradiating it with a sequence of optical pulses that are directed in sequence to various sites on the tissue. During the irradiation sequence, one or more tissue properties are measured at a site(s) that has already been irradiated. These measurements are used to adjust the parameters of subsequent optical pulses in the sequence.
摘要翻译：通过用顺序指向组织上的各个部位的光脉冲序列照射组织来治疗组织。在照射序列期间，在已经被照射的位点处测量一个或多个组织性质。这些测量用于调整序列中后续光脉冲的参数。

3. 发明申请

US20070093798A1 Method and Apparatus for Monitoring and Controlling Thermally Induced Tissue Treatment 审中-公开
标题翻译：用于监测和控制热诱导组织治疗的方法和装置
公开(公告)号：US20070093798A1
公开(公告)日：2007-04-26
申请号：US11468279
申请日：2006-08-29
申请人： Leonard DeBenedictis , Kin Chan , B. Stuart , Thomas Myers , Robert Sink , Basil Hantash , Oliver Stumpp
发明人： Leonard DeBenedictis , Kin Chan , B. Stuart , Thomas Myers , Robert Sink , Basil Hantash , Oliver Stumpp
IPC分类号： A61B18/18 , A61N1/00 , A61N5/06
CPC分类号： A61B18/203 , A61B18/14 , A61B34/20 , A61B2017/00022 , A61B2017/00106 , A61B2018/00452 , A61B2018/00476 , A61B2034/2048 , A61B2034/2051 , A61B2034/2055 , A61B2034/2059 , A61B2034/2063 , A61B2034/2065 , A61B2090/373 , A61B2090/378 , A61B2090/395 , A61B2090/3958 , A61N5/062
摘要： A method and apparatus for thermal treatment of tissue by irradiating the skin with electromagnetic energy is disclosed. Sources of electromagnetic energy include radio frequency (RF) generators, lasers, and flashlamps. The apparatus includes either a positional sensor or a dosage evaluation sensor, or both types of sensors. These sensors provide feedback to a controller. The controller may control the electromagnetic source parameters, the electromagnetic source activation, and/or the sensor measurement parameters. An additional scanning delivery unit may be operably coupled to the controller or to the sensors to provide a controlled distribution of electromagnetic energy to the target region of the skin. The use of positional measurement sensors and dosage evaluation sensors permits the controller to automatically determine the proper electromagnetic source parameters including, for example, pulse timing and pulse frequency.
摘要翻译：公开了一种通过用电磁能照射皮肤来热处理组织的方法和装置。电磁能源包括射频（RF）发生器，激光器和闪光灯。该装置包括位置传感器或剂量评估传感器，或两种类型的传感器。这些传感器向控制器提供反馈。控制器可以控制电磁源参数，电磁源激活和/或传感器测量参数。附加的扫描传送单元可以可操作地耦合到控制器或传感器，以向皮肤的目标区域提供受控的电磁能量分布。使用位置测量传感器和剂量评估传感器允许控制器自动确定适当的电磁源参数，包括例如脉冲定时和脉冲频率。

4. 发明申请

US20070093797A1 Method and Apparatus for Monitoring and Controlling Thermally Induced Tissue Treatment 失效
公开(公告)号：US20070093797A1
公开(公告)日：2007-04-26
申请号：US11468275
申请日：2006-08-29
申请人： Kin Chan , George Frangineas , Leonard DeBenedictis , Robert Sink
发明人： Kin Chan , George Frangineas , Leonard DeBenedictis , Robert Sink
IPC分类号： A61B18/18 , A61N5/06 , A61N1/00
CPC分类号： A61B18/203 , A61B18/14 , A61B34/20 , A61B2017/00022 , A61B2017/00106 , A61B2018/00452 , A61B2018/00476 , A61B2034/2048 , A61B2034/2051 , A61B2034/2055 , A61B2034/2059 , A61B2034/2063 , A61B2034/2065 , A61B2090/373 , A61B2090/378 , A61B2090/395 , A61B2090/3958 , A61N5/062
摘要： A method and apparatus for thermal treatment of tissue by irradiating the skin with electromagnetic energy is disclosed. Sources of electromagnetic energy include radio frequency (RF) generators, lasers, and flashlamps. The apparatus includes either a positional sensor or a dosage evaluation sensor, or both types of sensors. These sensors provide feedback to a controller. The controller may control the electromagnetic source parameters, the electromagnetic source activation, and/or the sensor measurement parameters. An additional scanning delivery unit may be operably coupled to the controller or to the sensors to provide a controlled distribution of electromagnetic energy to the target region of the skin. The use of positional measurement sensors and dosage evaluation sensors permits the controller to automatically determine the proper electromagnetic source parameters including, for example, pulse timing and pulse frequency.

5. 发明申请

US20060095096A1 Interchangeable tips for medical laser treatments and methods for using same 审中-公开
标题翻译：医疗激光治疗的可互换提示及使用方法
公开(公告)号：US20060095096A1
公开(公告)日：2006-05-04
申请号：US11223787
申请日：2005-09-08
申请人： Leonard DeBenedictis , John Black , Robert Sink , Kin Chan , Thomas Myers , George Frangineas , B. Stuart , Jeff Sobiech
发明人： Leonard DeBenedictis , John Black , Robert Sink , Kin Chan , Thomas Myers , George Frangineas , B. Stuart , Jeff Sobiech
IPC分类号： A61B18/18
CPC分类号： A61B18/203 , A61B90/98 , A61B2017/0046 , A61B2017/00482 , A61B2018/00452 , A61B2018/0047 , A61B2018/00988
摘要： A typical treatment system for use with tip embodiments includes an optical energy source, such as, for example, a laser. A set of tips may be interchangeably attached to the treatment system, for example to alter the system parameters and the treatment provided through the individual tips. Embodiments of the present invention include tips with a security chip and/or a memory. A security chip protects the treatment system from use with unauthorized tips, and the memory stores information about the tips and/or the treatment system to enhance the treatment
摘要翻译：用于尖端实施例的典型处理系统包括光能源，例如激光。一组尖端可以可互换地附接到治疗系统，例如以改变系统参数和通过各个提示提供的治疗。本发明的实施例包括具有安全芯片和/或存储器的尖端。安全芯片保护治疗系统免受未经授权的窍门的使用，并且存储器存储有关尖端和/或治疗系统的信息以增强治疗

6. 发明申请

US20080043306A1 High Speed, High Efficiency Optical Pattern Generator Using Rotating Optical Elements 失效
标题翻译：高速，高效光学图案发生器使用旋转光学元件
公开(公告)号：US20080043306A1
公开(公告)日：2008-02-21
申请号：US11849745
申请日：2007-09-04
申请人： Leonard DeBenedictis , C. Nabors , George Frangineas
发明人： Leonard DeBenedictis , C. Nabors , George Frangineas
IPC分类号： G02B26/12
CPC分类号： G02B26/105 , G02B13/0095 , G02B26/0875 , G02B26/10 , G02B27/30 , Y10S359/90
摘要： An optical pattern generator includes one or more multi-faceted rotating optical elements that introduce an offset that is rotation insensitive. The component that generates the offset is rotationally symmetric around the rotational axis of the optical element. Thus, as the optical element rotates, the effect of the offset component does not change. In addition, rotating optical elements may be designed to counteract unwanted optical effects of each other.
摘要翻译：光学图案发生器包括一个或多个引入旋转不敏感的偏移的多面旋转光学元件。产生偏移的分量围绕光学元件的旋转轴旋转对称。因此，当光学元件旋转时，偏移分量的影响不变。此外，旋转光学元件可以被设计成抵消彼此的不期望的光学效果。

7. 发明申请

US20070145146A1 High Speed, High Efficiency Optical Pattern Generator Using Rotating Optical Elements 失效
标题翻译：高速，高效光学图案发生器使用旋转光学元件
公开(公告)号：US20070145146A1
公开(公告)日：2007-06-28
申请号：US11679117
申请日：2007-02-26
申请人： Leonard DeBenedictis , C. Nabors , George Frangineas
发明人： Leonard DeBenedictis , C. Nabors , George Frangineas
IPC分类号： G06K7/10
CPC分类号： G02B26/105 , G02B13/0095 , G02B26/0875 , G02B26/10 , G02B27/30 , Y10S359/90
摘要： An optical pattern generator includes one or more multi-faceted rotating optical elements that introduce an offset that is rotation insensitive. The component that generates the offset is rotationally symmetric around the rotational axis of the optical element. Thus, as the optical element rotates, the effect of the offset component does not change. In addition, rotating optical elements may be designed to counteract unwanted optical effects of each other.
摘要翻译：光学图案发生器包括一个或多个引入旋转不敏感的偏移的多面旋转光学元件。产生偏移的分量围绕光学元件的旋转轴旋转对称。因此，当光学元件旋转时，偏移分量的影响不变。此外，旋转光学元件可以被设计成抵消彼此的不期望的光学效果。

8. 发明申请

US20060119920A1 High speed, high efficiency optical pattern generator using rotating optical elements 有权
公开(公告)号：US20060119920A1
公开(公告)日：2006-06-08
申请号：US11339097
申请日：2006-01-24
申请人： Leonard DeBenedictis , C. Nabors , George Frangineas
发明人： Leonard DeBenedictis , C. Nabors , George Frangineas
IPC分类号： G02B26/08
CPC分类号： G02B26/105 , G02B13/0095 , G02B26/0875 , G02B26/10 , G02B27/30 , Y10S359/90
摘要： An optical pattern generator includes one or more multi-faceted rotating optical elements that introduce an offset that is rotation insensitive. The component that generates the offset is rotationally symmetric around the rotational axis of the optical element. Thus, as the optical element rotates, the effect of the offset component does not change. In addition, rotating optical elements may be designed to counteract unwanted optical effects of each other.

9. 发明申请

US20050259306A1 Two-dimensional optical scan system using a counter-rotating disk scanner 有权
标题翻译：二维光学扫描系统采用反向旋转扫描仪
公开(公告)号：US20050259306A1
公开(公告)日：2005-11-24
申请号：US10914860
申请日：2004-08-09
申请人： Barry Broome , George Frangineas , Leonard DeBenedictis
发明人： Barry Broome , George Frangineas , Leonard DeBenedictis
IPC分类号： G02B26/08 , G02B26/10 , G02B26/12
CPC分类号： G02B26/106 , G02B26/0875 , G02B26/10 , G03B21/14
摘要： A counter-rotating disk scanner together with another scan mechanism provides two-dimensional optical scanning. The counter-rotating disk scanner includes counter-rotating scan disks that implement the scanning action as they rotate through an optical axis of the system.
摘要翻译：反向旋转磁盘扫描器与另一扫描机构一起提供二维光学扫描。反向旋转盘扫描器包括反向旋转的扫描盘，当它们旋转通过系统的光轴时，其执行扫描动作。

10. 发明申请

US20080015557A1 Apparatus and Method for Adjustable Fractional Optical Dermatological Treatment 有权
标题翻译：可调分数光学皮肤病治疗的装置和方法
公开(公告)号：US20080015557A1
公开(公告)日：2008-01-17
申请号：US11778012
申请日：2007-07-13
申请人： Kin Chan , George Frangineas , David Dewey , Leonard DeBenedictis
发明人： Kin Chan , George Frangineas , David Dewey , Leonard DeBenedictis
IPC分类号： A61B18/20
CPC分类号： A61B18/203 , A61B18/20 , A61B2018/00452 , A61B2018/00636 , A61B2018/20351
摘要： In a fractional treatment system, an adjustable mechanism can be used to adjust the beam shape, beam numerical aperture, beam focus depth, and/or beam size to affect the treatment depth and or the character of the resulting lesions. Adjustment of these parameters can improve the efficiency and efficacy of treatment. Illustrative examples of adjustable mechanisms include a set of spacers of different lengths, a rotatable turret with lens elements of different focal distances, an optical zoom lens, and a mechanical adjustment apparatus for adjusting the spacing between two optical lens elements. In one aspect, the fractional treatment is configured with a laser wavelength that is selected such that absorption of the laser wavelength within the tissue decreases as the tissue is heated by the laser (e.g., 1480-1640 nm). Desirably, the laser wavelength is primarily absorbed within a treated region of skin by water and has a thermally adjusted absorption coefficient within the range of about 7 cm−1 to about 26 cm−1.
摘要翻译：在分数处理系统中，可以使用可调节的机构来调整光束形状，光束数值孔径，光束聚焦深度和/或光束尺寸，以影响治疗深度或所得损伤的特征。这些参数的调整可以提高治疗的效率和疗效。可调节机构的说明性实例包括一组不同长度的间隔物，具有不同焦距的透镜元件的可旋转转台，光学变焦透镜和用于调节两个光学透镜元件之间的间距的机械调节装置。在一个方面，分数处理配置有激光波长，激光波长被选择为使得组织内的激光波长的吸收随着组织被激光加热而减小（例如，1480-1640nm）。期望地，激光波长主要被水吸收在皮肤的处理区域内，并且具有在约7cm -1至约26cm -1的范围内的热调节吸收系数， SUP>。

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