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    • 2. 发明授权
    • Continuous, non-invasive technique for measuring blood pressure using impedance plethysmography
    • 使用阻抗体积描记法测量血压的连续,非侵入性技术
    • US06648828B2
    • 2003-11-18
    • US09683916
    • 2002-03-01
    • Bruce A. FriedmanRichard MederoLawrence T. HershSai Kolluri
    • Bruce A. FriedmanRichard MederoLawrence T. HershSai Kolluri
    • A61B502
    • A61B5/0285A61B5/021A61B5/02125A61B5/0295
    • Blood pressure is measured using the pulse transit time required for the blood volume pulse to propagate between two locations in an animal. Impedance plethysmography is employed to detect when the blood volume pulse occurs at one location. The plethysmograph may detect thoracic impedance to determine when the aortic heart valve opens or it may detect impedance at one location on a limb of the animal. Occurrence of the blood volume pulse at another location can be determined by impedance plethysmography or another technique, such as pulse oximetry. The calculation of cardiac stroke volume can be employed to compensate the derivation of the blood pressure for effects due to blood vessel compliance. A nonblood pressure monitor may periodically provide a reference blood pressure measurement that is used calibrate derivation of the blood pressure based on the pulse transit time.
    • 使用血液体积脉冲在动物的两个位置之间传播所需的脉搏传播时间来测量血压。 采用阻抗体积描记法检测血液体积脉搏何时出现在一个位置。 体积描记器可以检测胸部阻抗以确定主动脉瓣心脏瓣膜何时打开,或者可以在动物肢体的一个位置处检测阻抗。 可以通过阻抗体积描记法或其他技术(例如脉搏血氧测定法)来确定另一位置处的血容量脉冲的发生。 心脏搏动量的计算可用于补偿由于血管依从性引起的血压的推导。 非血压监视器可以周期性地提供参考血压测量,其用于基于脉冲传播时间来校准血压的推导。
    • 5. 发明授权
    • Computation of blood pressure using different signal processing channels
    • 使用不同的信号处理通道计算血压
    • US07775987B2
    • 2010-08-17
    • US11284206
    • 2005-11-21
    • Lawrence T. HershSai KolluriBruce A. FriedmanRichard Medero
    • Lawrence T. HershSai KolluriBruce A. FriedmanRichard Medero
    • A61B5/02
    • A61B5/022A61B5/02225A61B5/7207
    • A blood pressure measurement system that utilizes a non-invasive blood pressure (NIBP) monitor having a blood pressure cuff and pressure transducer. The measurement system provides a plurality of separate processing techniques that each receive a plurality of oscillometric data values from the pressure transducer. Each of the processing techniques separately constructs an oscillometric envelope based upon the oscillometric data values. Based upon the plurality of separate oscillometric envelopes, the system compares the envelopes and develops a calculated blood pressure from the plurality of envelopes. The calculated blood pressure is then displayed by the NIBP system. The plurality of oscillometric envelopes can be compared and combined in different manners to calculate the patient's blood pressure from the plurality of different processing techniques.
    • 一种血压测量系统,其利用具有血压袖带和压力换能器的非侵入性血压(NIBP)监测器。 测量系统提供多个单独的处理技术,每个处理技术从压力传感器接收多个示波数据值。 每个处理技术基于示波数据值分别构建示波包络。 基于多个单独的示波包络,系统比较信封并从多个信封形成计算出的血压。 然后计算的血压由NIBP系统显示。 多个示波包络可以以不同的方式进行比较和组合,以从多种不同的处理技术计算出患者的血压。
    • 7. 发明授权
    • Method of controlling blood pressure cuff deflation
    • 控制血压袖带放气的方法
    • US07226421B1
    • 2007-06-05
    • US11290272
    • 2005-11-30
    • Lawrence T. HershSai KolluriBruce A. FriedmanRichard Medero
    • Lawrence T. HershSai KolluriBruce A. FriedmanRichard Medero
    • A61B5/00
    • A61B5/0225A61B5/02141A61B5/02225
    • A method of operating a non-invasive blood pressure (NIBP) monitor that includes a blood pressure cuff and a pressure transducer. The method initially inflates the blood pressure cuff to a level above systolic pressure and begins to deflate the pressure cuff using a continuous or linear deflation technique. During the linear deflation of the pressure cuff, the oscillation pulses from the pressure transducer are obtained and compared to predicted pulse estimates. If the obtained oscillation pulses vary from the predicted pulse estimates, the linear deflation technique is interrupted and the pressure cuff is then deflated in a sequence of distinct pressure steps. During each pressure step, the oscillation pulses are obtained and the pressure cuff is not deflated to the next pressure step until the oscillation pulses correspond to each other.
    • 一种操作包括血压袖带和压力换能器的非侵入性血压(NIBP)监测器的方法。 该方法首先将血压袖带膨胀至高于收缩压的水平,并使用连续或线性放气技术开始压缩压力袖带。 在压力袖带的线性放气期间,获得来自压力传感器的振荡脉冲并与预测的脉冲估计值进行比较。 如果获得的振荡脉冲从预测的脉冲估计变化,则线性放气技术被中断,并且压力袖带然后以不同压力步骤的顺序放气。 在每个压力步骤期间,获得振荡脉冲,并且压力袖带不会放气到下一个压力步骤,直到振荡脉冲彼此对应。
    • 9. 发明授权
    • Method and system utilizing SpO2 plethysmograph signal to qualify NIBP pulses
    • 使用SpO2体积描记器信号来限定NIBP脉冲的方法和系统
    • US07300404B1
    • 2007-11-27
    • US11470701
    • 2006-09-07
    • Sai KolluriLawrence T. HershRichard Medero
    • Sai KolluriLawrence T. HershRichard Medero
    • A61B5/00
    • A61B5/02255A61B5/02225
    • A method and system for operating a non-invasive blood pressure monitor that utilizes an SpO2 plethysmographic signal to reduce the time required to obtain an estimation of a patient's blood pressure. During operation of the NIBP monitor, the NIBP monitor utilizes the SpO2 plethysmographic signal to determine a timing period and a deflation period for each pulse associated with the patient's heartbeat. Upon receiving an oscillation pulse, the NIBP monitor determines the oscillation amplitude during the timing period and deflates the blood pressure cuff during the deflation period immediately following the timing period. Preferably, the deflation period occurs during the same oscillation pulse used to calculate the oscillation pulse amplitude to decrease the amount of time required to obtain a blood pressure estimate from the patient.
    • 一种用于操作使用SpO 2体积描记信号的非侵入性血压监测器的方法和系统,以减少获得对患者血压的估计所需的时间。 在NIBP监视器的操作期间,NIBP监视器利用SpO 2体积描记信号来确定与患者心跳相关联的每个脉冲的定时周期和放气周期。 在接收到振荡脉冲时,NIBP监视器确定定时期间的振荡幅度,并且在定时周期之后的放气期间缩小血压袖带。 优选地,放气周期发生在用于计算振荡脉冲幅度的相同振荡脉冲期间,以减少从患者获得血压估计所需的时间量。