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    • 6. 发明授权
    • Pharmaceutical compositions
    • 药物组合物
    • US07956198B2
    • 2011-06-07
    • US12092930
    • 2006-11-08
    • Jitendra A. SattigeriVinay S. Bansal
    • Jitendra A. SattigeriVinay S. Bansal
    • C07D207/00
    • C07D207/34A61K31/397A61K31/40A61K31/4025A61K31/44A61K31/4439A61K31/445A61K31/47A61K31/554A61K31/70A61K45/06C07D405/06A61K2300/00
    • This invention relates to a combination product or medicament comprising at least one novel substituted pyrrole derivative and one or more dyslipidemic agents, antiobesity agents, antihyperglycaemic agents, anti-inflammatory agents or mixture thereof. Also provided herein are the pharmaceutical compositions comprising at least one novel substituted pyrrole derivative and one or more dyslipidemic agents, antiobesity agents, antihyperglycaemic agents, anti-inflammatory agents or mixture thereof and optionally together with at least one pharmaceutically acceptable carrier, and methods for the treatment or prophylaxis of cardiovascular diseases, Alzheimer's disease, obesity, diabetes or inflammatory diseases comprising administering to a mammal in need thereof therapeutically effective amounts of combination pharmaceutical composition comprising at least one novel substituted pyrrole derivative and one or more dyslipidemic agents, antiobesity agents, antihyperglycaemic agents, anti-inflammatory agents or mixtures thereof.
    • 本发明涉及包含至少一种新的取代的吡咯衍生物和一种或多种血脂异常剂,抗肥胖剂,抗高血糖药,抗炎剂或其混合物的组合产品或药物。 本文还提供了包含至少一种新的取代的吡咯衍生物和一种或多种血脂变剂,抗肥胖剂,抗高血糖药,抗炎剂或其混合物以及任选地与至少一种药学上可接受的载体的药物组合物,以及用于 治疗或预防心血管疾病,阿尔茨海默氏病,肥胖症,糖尿病或炎性疾病,包括向有需要的哺乳动物施用治疗有效量的组合药物组合物,其包含至少一种新的取代的吡咯衍生物和一种或多种血脂异常剂,抗肥胖剂,抗高血糖药 药剂,抗炎剂或其混合物。