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    • 1. 发明申请
    • METHODS FOR CONTROLLING ONE OR MORE PARAMETERS OF A FLOW CYTOMETER TYPE MEASUREMENT SYSTEM
    • 用于控制流量计细胞类型测量系统的一个或多个参数的方法
    • WO2005017499A2
    • 2005-02-24
    • PCT/US2004/026225
    • 2004-08-11
    • LUMINEX CORPORATIONROTH, Wayne, D.MOORE, Douglas, E.
    • ROTH, Wayne, D.MOORE, Douglas, E.
    • G01N15/14
    • G01N15/1404G01N15/1012G01N21/645G01N2015/1415G01N2015/1477G01N2201/12746
    • Various methods for controlling one or more parameters of a flow cytometer type measurement system are provided. One embodiment includes monitoring parameter(s) of the measurement system during measurements of sample microspheres. The method also includes altering the parameter(s) in real time based on the monitoring. Another method includes monitoring a temperature proximate to the measurement system. One such method includes altering a bias voltage of an avalanche photo diode in response to the temperature using empirically derived data. A different such method includes altering output signals of a photomultiplier tube in response to the temperature using a characteristic curve. Some methods include monitoring a temperature of a fluid, in which sample microspheres are disposed, that will flow through the flow cytometer type measurement system. This method also includes determining a velocity of the sample microspheres in the measurement system from a viscosity of the fluid at the temperature.
    • 提供了用于控制流式细胞仪类型测量系统的一个或多个参数的各种方法。 一个实施例包括在测量样本微球体期间监测测量系统的参数。 该方法还包括基于监测实时改变参数。 另一种方法包括监测接近测量系统的温度。 一种这样的方法包括使用经验导出的数据来响应于温度改变雪崩光电二极管的偏置电压。 不同的这种方法包括使用特性曲线响应于温度改变光电倍增管的输出信号。 一些方法包括监测将流过流式细胞仪类型测量系统的流体的温度,其中设置有样本微球体。 该方法还包括根据温度下流体的粘度确定测量系统中的样品微球的速度。