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1. 发明申请

WO2010009848A2 VERFAHREN ZUM HERSTELLEN EINES MEHRSCHICHTENVERBUNDES AUF EINER CIP-FÄHIGEN BESCHICHTUNGSANLAGE UND VERWENDUNG DES DAMIT HERGESTELLTEN MEHRSCHICHTENVERBUNDES FÜR DIE TRANSDERMALE APPLIKATION ODER DIE APPLIKATION IN KÖRPERHÖHLEN 审中-公开
标题翻译：一种用于生产多层复合在CIP能力的镀膜设备和生产的多层复合材料用于透皮应用程序中使用或用于体洞穴中的应用
公开(公告)号：WO2010009848A2
公开(公告)日：2010-01-28
申请号：PCT/EP2009/005239
申请日：2009-07-20
申请人： LTS LOHMANN THERAPIE-SYSTEME AG , BRATHUHN, Rudi , SCHWARZ, Peter , SCHÄFER, Wolfgang
发明人： BRATHUHN, Rudi , SCHWARZ, Peter , SCHÄFER, Wolfgang
IPC分类号： F26B13/10 , F26B25/00
CPC分类号： F26B13/00 , F26B25/00
摘要： Das Herstellverfahren für einen Ein- oder Mehrschichtenverbund umfasst mehrere Schritte, wobei zuerst eine oder mehrere Schichten auf einem Trägermaterial durch Beschichten mit einer flüssigen Komponente aufgebracht werden, danach der beschichtete Mehrschichtenverbund getrocknet wird und danach der getrocknete Ein- oder Mehrschichtenverbund aufgerollt wird, wobei als letzter Schritt die Anlage gereinigt wird. Während der Trocknung des beschichteten Mehrschichtenverbundes wird dabei im Trockenofen (5) der Luftkreislauf vollständig auf Frischluftzufuhr eingestellt, und der Innenraum des Trockenofens ist kontrolliert reinigbar ausgestaltet. Das bedeutet, dass alle Bauteile des Trockenofens (5), die mit dem darin produzierten Produkt in Berührung kommen können, zum Zweck einer GMP- gerechten Reinigung nicht ausgebaut werden müssen, sondern mit Hilfe des in den Trockenofen (5) integrierten Systems in CIP-Technik gereinigt werden können. Ferner ist das äußere Gehäuse des Trockenofens so ausgestaltet, dass der obere Teil (11) des Trockenofens (5) nach oben abgehoben werden kann, und alle Einbauteile im Innern des Trockenofens sind so konstruiert, dass eine Demontage zu Reinigungszwecken nicht erforderlich ist. Alle Transportwalzen (17), mit denen der beschichtete Ein- oder Mehrschichtverbund (14) durch den Trockenofen (5) und die einzelnen Trockenzonen (T1 bis Tx) hindurch bewegt wird, sind als Hohlwellen ausgestaltet und mit Sprühdüsen ausgerüstet.
摘要翻译：用于单个或多层复合物的制造方法包括多个步骤，所述上通过用液体组分涂布载体材料第一一个或多个层被施加，则涂覆的多层复合物被干燥，然后将干燥的单或多层复合卷起，与最后步骤中，系统被清洁。在涂覆的多层复合材料的干燥，而空气循环干燥炉（5），和干燥炉的内部被设计来控制清洁的被完全地设置到的新鲜空气供应。这意味着，干燥炉（5），其能够与所生产的产品接触在其中，为GMP正确清洁的目的的所有组件不需要被移除，但随着在干燥的帮助炉（5）的集成系统在CIP 技术可以清洗。此外，干燥炉的外壳被设计成使得所述干燥炉（5）的上部（11）可被向上方抬起，而所有的内置在干燥的内饰件烘箱被构造成不要求拆卸为了清洁的目的。所有的输送辊（17），其通过干燥炉（5）和各个干燥区（T1于Tx）通过涂覆单或多层复合材料（14）被设计成空心轴移动，并设置有喷嘴。

2. 发明申请

WO2003061635A3 METHOD AND DEVICE FOR PRODUCING PRODUCTS IN WEB FORM 审中-公开
公开(公告)号：WO2003061635A3
公开(公告)日：2003-07-31
申请号：PCT/EP2003/000334
申请日：2003-01-15
申请人： LTS LOHMANN THERAPIE-SYSTEME AG , NEULAND, Detlev , SCHÄFER, Wolfgang , SCHWARZ, Peter
发明人： NEULAND, Detlev , SCHÄFER, Wolfgang , SCHWARZ, Peter
IPC分类号： A61K9/70
摘要： The present invention pertains to a method for producing products in web form in which a coating mass comprising one or more active-ingredients first is applied onto the surface of a transfer support web, subsequently the composite of transfer support web and coating is treated thermally, then an intermediate support material is applied onto the coating and finally the product in web form comprising the intermediate support material and the coating are separated from the transfer support web, wound up and stored. The transfer support web used thereby is performed as an endless loop. The transfer support web performed as an endless loop is recirculated to be applied again with the coating after its regeneration. The invention pertains also to a device suitable for performing the method.

3. 发明申请

WO2003059542A1 METHOD FOR NEUTRALIZING OR RECYCLING CARRIER MATERIALS FOR FILM-LIKE COATINGS 审中-公开
标题翻译：中空涂层或回收载体材料的方法
公开(公告)号：WO2003059542A1
公开(公告)日：2003-07-24
申请号：PCT/EP2003/000252
申请日：2003-01-14
申请人： LTS LOHMANN THERAPIE-SYSTEME AG , NEULAND, Detlev , SCHÄFER, Wolfgang , SCHWARZ, Peter
发明人： NEULAND, Detlev , SCHÄFER, Wolfgang , SCHWARZ, Peter
IPC分类号： B09B3/00
CPC分类号： F26B3/30 , B08B7/0071 , B09B3/00 , B09B3/0075
摘要： Carrier materials, such as paper, polymers or composite materials composed of these and/or thin metal foils, which are used in the manufacture of sheet-like or film-like forms of administration of drugs, food, cosmetics and the like for oral application, and which are contaminated during the manufacture of these forms of administration by substances penetrating the carrier and stemming from the active ingredient containing coating applied to that carrier, can be neutralized, i.e. these undesired substance can be removed from the carrier, by an additional thermal treatment making the carrier reusable for further coating processes.
摘要翻译：载体材料，例如由这些和/或薄金属箔组成的纸，聚合物或复合材料，用于制造用于口服应用的药物，食品，化妆品等的片状或膜状给药形式，并且在制造这些形式的施用形式时被污染的物质通过穿透载体的物质和源于施加到该载体的含有活性成分的涂层引起，可以被中和，即这些不需要的物质可以通过额外的热量从载体中除去处理使得载体可重复使用以用于进一步的涂布过程。

4. 发明公开

EP2307837A2 VERFAHREN ZUM HERSTELLEN EINES MEHRSCHICHTENVERBUNDES AUF EINER CIP-FÄHIGEN BESCHICHTUNGSANLAGE UND VERWENDUNG DES DAMIT HERGESTELLTEN MEHRSCHICHTENVERBUNDES FÜR DIE TRANSDERMALE APPLIKATION ODER DIE APPLIKATION IN KÖRPERHÖHLEN 有权
标题翻译：一种用于生产多层复合在CIP能力的镀膜设备和生产的多层复合材料用于透皮应用程序中使用或用于体洞穴中的应用
公开(公告)号：EP2307837A2
公开(公告)日：2011-04-13
申请号：EP09777292.5
申请日：2009-07-20
申请人： LTS LOHMANN Therapie-Systeme AG
发明人： BRATHUHN, Rudi , SCHWARZ, Peter , SCHÄFER, Wolfgang
IPC分类号： F26B13/00 , F26B25/00
CPC分类号： F26B13/00 , F26B25/00
摘要： The invention relates to a method of production for a mono- or multilayer compound, comprising several steps, wherein first one or several layers are applied onto a carrier material by coating with a liquid component, the multilayer compound is then dried and the dried mono- or multilayer compound is then rolled up, wherein, in a final step, the installation is cleaned. During the drying of the coated multilayer compound, the air circuit in the drying oven (5) is entirely set to fresh air supply, and the inner chamber of the drying oven is configured to be cleaned in a controlled manner. As a result, all components of the drying oven (5), which can come into contact with the product produced therein, do not have to be removed for the purpose of a GMP-compliant cleaning, but can be cleaned with the aid of the system using CIP technology which is integrated into the drying oven (5). Furthermore, the outer housing of the drying oven is designed in such a manner that the upper part (11) of the drying oven (5) can be lifted off in the upward direction, and all assembly parts in the interior of the drying oven are designed such that a dismounting for cleaning purposes is not required. All transport rollers (17), by means of which the coated mono- or multilayer compound (14) is moved through the drying oven (5) and the individual drying zones (T1 to Tx), are designed as hollow shafts and provided with spraying nozzles.

5. 发明授权

EP1471893B1 METHOD AND DEVICE FOR PRODUCING PRODUCTS IN WEB FORM 有权
标题翻译：方法和设备生产成型履带板
公开(公告)号：EP1471893B1
公开(公告)日：2006-11-22
申请号：EP03706359.1
申请日：2003-01-15
申请人： LTS LOHMANN Therapie-Systeme AG
发明人： NEULAND, Detlev , SCHÄFER, Wolfgang , SCHWARZ, Peter
IPC分类号： A61K9/70 , A61K9/00
CPC分类号： B05D1/286 , A61J3/00 , A61K9/0056 , A61K9/006 , A61K9/7007 , B29C41/28
摘要： The present invention pertains to a method for producing products in web form in which a coating mass comprising one or more active-ingredients first is applied onto the surface of a transfer support web, subsequently the composite of transfer support web and coating is treated thermally, then an intermediate support material is applied onto the coating and finally the product in web form comprising the intermediate support material and the coating are separated from the transfer support web, wound up and stored. The transfer support web used thereby is performed as an endless loop. The transfer support web performed as an endless loop is recirculated to be applied again with the coating after its regeneration. The invention pertains also to a device suitable for performing the method.

6. 发明公开

EP1471893A2 METHOD AND DEVICE FOR PRODUCING PRODUCTS IN WEB FORM 有权
标题翻译：方法和设备生产成型履带板
公开(公告)号：EP1471893A2
公开(公告)日：2004-11-03
申请号：EP03706359.1
申请日：2003-01-15
申请人： LTS LOHMANN Therapie-Systeme AG
发明人： NEULAND, Detlev , SCHÄFER, Wolfgang , SCHWARZ, Peter
IPC分类号： A61K9/70 , A61K9/00
CPC分类号： B05D1/286 , A61J3/00 , A61K9/0056 , A61K9/006 , A61K9/7007 , B29C41/28
摘要： The present invention pertains to a method for producing products in web form in which a coating mass comprising one or more active-ingredients first is applied onto the surface of a transfer support web, subsequently the composite of transfer support web and coating is treated thermally, then an intermediate support material is applied onto the coating and finally the product in web form comprising the intermediate support material and the coating are separated from the transfer support web, wound up and stored. The transfer support web used thereby is performed as an endless loop. The transfer support web performed as an endless loop is recirculated to be applied again with the coating after its regeneration. The invention pertains also to a device suitable for performing the method.

7. 发明授权

EP2307837B1 VERFAHREN ZUM HERSTELLEN EINES MEHRSCHICHTENVERBUNDES AUF EINER CIP-FÄHIGEN BESCHICHTUNGSANLAGE 有权
公开(公告)号：EP2307837B1
公开(公告)日：2018-09-05
申请号：EP09777292.5
申请日：2009-07-20
申请人： LTS LOHMANN Therapie-Systeme AG
发明人： BRATHUHN, Rudi , SCHWARZ, Peter , SCHÄFER, Wolfgang
IPC分类号： F26B13/00 , F26B25/00
CPC分类号： F26B13/00 , F26B25/00

8. 发明授权

EP1194349B1 BLISTERKARTONVERPACKUNG FÜR EMPFINDLICHES PACKGUT MIT LEICHTFLÜCHTIGEN UND/ODER FEUCHTIGKEITSEMPFINDLICHEN KOMPONENTEN 有权
标题翻译： BLISTERKARTONVERPACKUNG与EASY易失性和/或湿度传感电敏感元器件BUNDLES
公开(公告)号：EP1194349B1
公开(公告)日：2003-10-15
申请号：EP00947890.0
申请日：2000-06-29
申请人： LTS Lohmann Therapie-Systeme AG
发明人： PALM, Detlef , SCHWARZ, Peter
IPC分类号： B65D75/36
CPC分类号： B65D75/366 , B65D73/0092 , B65D75/36
摘要： The invention relates to a blister box pack for sensitive packaged goods with highly volatile and/or moisture-sensitive components. The inventive blister box pack is configured in such a way as to prevent moisture from penetrating and/or volatile components from escaping, and comprises a blister card (1) which is configured in one piece or in two pieces, e.g. in the form of a folded card (1, 1'). Said blister card serves as a support for the blister cap (2), which consists of transparent material. The blister card and the blister cap are interconnected by at least one sealing coating film (3, 3'). The invention is characterized in that a barrier layer (4), which is impermeable to water vapor and/or volatile components, is positioned between the blister card (1) and the blister cap (2). Said barrier layer is connected to the blister card (1) on one side and the blister cap (2) on the other side by at least one sealing coating-pressure-sensitive adhesive film, in a media-tight manner.

9. 发明公开

EP1194349A1 BLISTERKARTONVERPACKUNG FÜR EMPFINDLICHES PACKGUT MIT LEICHTFLÜCHTIGEN UND/ODER FEUCHTIGKEITSEMPFINDLICHEN KOMPONENTEN 有权
标题翻译： BLISTERKARTONVERPACKUNG与EASY易失性和/或湿度传感电敏感元器件BUNDLES
公开(公告)号：EP1194349A1
公开(公告)日：2002-04-10
申请号：EP00947890.0
申请日：2000-06-29
申请人： LTS Lohmann Therapie-Systeme AG
发明人： PALM, Detlef , SCHWARZ, Peter
IPC分类号： B65D75/36
CPC分类号： B65D75/366 , B65D73/0092 , B65D75/36
摘要： The invention relates to a blister box pack for sensitive packaged goods with highly volatile and/or moisture-sensitive components. The inventive blister box pack is configured in such a way as to prevent moisture from penetrating and/or volatile components from escaping, and comprises a blister card (1) which is configured in one piece or in two pieces, e.g. in the form of a folded card (1, 1'). Said blister card serves as a support for the blister cap (2), which consists of transparent material. The blister card and the blister cap are interconnected by at least one sealing coating film (3, 3'). The invention is characterized in that a barrier layer (4), which is impermeable to water vapor and/or volatile components, is positioned between the blister card (1) and the blister cap (2). Said barrier layer is connected to the blister card (1) on one side and the blister cap (2) on the other side by at least one sealing coating-pressure-sensitive adhesive film, in a media-tight manner.

10. 发明申请

WO2011054866A1 POLYCARBONATZUSAMMENSETZUNG MIT VERBESSERTER FLAMMWIDRIGKEIT FÜR EXTRUSIONSANWENDUNGEN 审中-公开
标题翻译：具有改进的用于挤出应用的阻燃性的聚碳酸酯组合物
公开(公告)号：WO2011054866A1
公开(公告)日：2011-05-12
申请号：PCT/EP2010/066736
申请日：2010-11-03
申请人： BAYER MATERIALSCIENCE AG , MEYER, Alexander , KRAUTER, Berit , RÜDIGER, Claus , BLASCHKE, Ulrich , SCHWARZ, Peter
发明人： MEYER, Alexander , KRAUTER, Berit , RÜDIGER, Claus , BLASCHKE, Ulrich , SCHWARZ, Peter
IPC分类号： C08K5/523 , C08L33/08 , C08L33/10 , C08L67/02 , C08L69/00
CPC分类号： B32B27/18 , B32B27/36 , C08K5/523 , C08K2201/014 , C08L51/003 , C08L51/04 , C08L67/02 , C08L69/00 , E04C2/543 , Y10T428/31507 , C08L2666/02 , C08L2666/84 , C08L2666/70
摘要： Die vorliegende Erfindung betrifft Zusammensetzungen enthaltend flammgeschütztes Polycarbonat, welche sich für die Herstellung flammwidriger und milchweiß-gefärbter Platten eignen.
摘要翻译：本发明涉及含有阻燃聚碳酸酯的组合物，其可用于制备阻燃剂和乳白色板

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