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1. 发明申请

WO2010005257A3 CONTROLLED-RELEASE PHARMACEUTICAL PREPARATION CONTAINING NICORANDIL 审中-公开
标题翻译：含有尼可地尔的控制释放药物制剂
公开(公告)号：WO2010005257A3
公开(公告)日：2010-04-01
申请号：PCT/KR2009003783
申请日：2009-07-10
申请人： LG LIFE SCIENCES LTD , CHUNG YOUNG SIK , KIM YUN SIK , LIM CHANG BAEG , LEE SUNG HACK , KANG HYUN SU , CHUNG SOO YONG
发明人： CHUNG YOUNG SIK , KIM YUN SIK , LIM CHANG BAEG , LEE SUNG HACK , KANG HYUN SU , CHUNG SOO YONG
IPC分类号： A61K9/22 , A61K9/20 , A61K31/44 , A61K47/00
CPC分类号： A61K9/00
摘要： The present invention relates to a drug delivery system for oral administration of a new, controlled-release drug for angina treatment, and more specifically to a sustained-release pharmaceutical preparation containing Nicorandil that uses a polysaccharide, fatty acid ester, and optionally an alkalinizing agent so that it is bioavailable in vivo and also exhibits a release pattern wherein Nicorandil can be continuously released from the preparation over 12 to 24 hours following administration.
摘要翻译：本发明涉及口服给药用于心绞痛治疗的新型控释药物的给药系统，并且更具体地涉及含有尼可地尔的缓释药物制剂，其使用多糖，脂肪酸酯和任选的碱化剂因此它在体内是生物可利用的并且还表现出释放模式，其中尼可地尔可以在给药后12至24小时内从制剂中连续释放。

2. 发明公开

KR20070093656A NOVEL PROCESSES FOR THE PREPARATION OF LOSARTAN, AND A BENZYLIMIDAZOL DERIVATIVE AS USEFUL INTERMEDIATE FOR PREPARATION THEREOF 审中-公开
标题翻译：用于制备洛沙坦的新方法和作为其制备的有用的中间体的苯并咪唑衍生物
公开(公告)号：KR20070093656A
公开(公告)日：2007-09-19
申请号：KR20060023754
申请日：2006-03-14
申请人： LG LIFE SCIENCES LTD
发明人： KIM YUN SIK , PARK BONG JUN
IPC分类号： C07D233/68 , C07D233/66
摘要： A method for preparing a novel imidazole derivative is provided to obtain the imidazole derivative useful as an important intermediate of a losartan derivative used for selectively synthesizing losartan with high yield. And a novel method for preparing the losartan using the imidazole derivative is provided. A method for preparing a compound represented by the formula(2) comprises the steps of: (a) chloroformylating a compound represented by the formula(4) in the presence of a chlorinating agent and a formylating agent to form a compound represented by the formula(3); and (b) reducing an aldehyde group of the compound of the formula(3) into an alcohol. The method for preparing a compound represented by the formula(1) comprises the steps of: (a) performing a [3+2] ring-addition reaction on the compound of the formula(2) with an azide-containing dieneophile in the presence of an anion activating agent to form a compound represented by the formula(1-1); and (b) treating the compound of the formula(1-1) with potassium hydroxide.
摘要翻译：提供一种制备新型咪唑衍生物的方法，以获得可用作用于以高产率选择性合成氯沙坦的氯沙坦衍生物的重要中间体的咪唑衍生物。并提供了使用咪唑衍生物制备氯沙坦的新方法。制备由式（2）表示的化合物的方法包括以下步骤：（a）在氯化剂和甲酰化剂的存在下将由式（4）表示的化合物氯甲酰化以形成由式（3）; 和（b）将式（3）化合物的醛基还原成醇。由式（1）表示的化合物的制备方法包括以下步骤：（a）在含有叠氮化物的亲油性物质的情况下，在式（2）的化合物上进行[3 + 2]环加成反应的阴离子活化剂以形成由式（1-1）表示的化合物; 和（b）用氢氧化钾处理式（1-1）的化合物。

3. 发明申请

WO2011159024A3 FAT COMPOSITION FOR CHOCOLATE AND CONFECTIONERY 审中-公开
标题翻译：巧克力和糖果的脂肪组合物
公开(公告)号：WO2011159024A3
公开(公告)日：2012-03-01
申请号：PCT/KR2011003478
申请日：2011-05-12
申请人： CJ CHEILJEDANG CORP , KIM MI JUNG , LEE SANG BUM , KIM YUN SIK , KANG JI HYUN , LEE YUN JEONG , PARK SEUNG WON , KIM TAI JOON
发明人： KIM MI JUNG , LEE SANG BUM , KIM YUN SIK , KANG JI HYUN , LEE YUN JEONG , PARK SEUNG WON , KIM TAI JOON
IPC分类号： A23G1/36 , A23G1/30 , A23G1/38
CPC分类号： A23G1/36 , A23D9/04 , A23G1/38 , A23G3/40 , C11C3/10
摘要： The present invention relates to a fat composition for chocolate and confectionery prepared by the following steps: mixing vegetable oil and fatty acid or derivatives thereof to prepare an oil as a base material; and enzymatically transesterifying the oil as a base material, wherein a POS/SOS ratio is 2-12 and a POS content is 30-55 wt% in a triglyceride composition. The fat composition according to the present invention has a triglyceride composition similar to that of cocoa butter having a high POS content, thereby showing a solid fat content (SFC) curve having a steep slope specific to cocoa butter, and thus refreshingly melts in the mouth and can be used as a cocoa butter equivalent having a non-hard and soft feeling when eating. In addition, the fat composition of the present invention has superior bloom resistance over a commercial cocoa butter replacer.
摘要翻译：本发明涉及通过以下步骤制备的用于巧克力和糖食的脂肪组合物：将植物油和脂肪酸或其衍生物混合以制备油作为基料; 并将油作为基料进行酶促酯交换反应，其中在甘油三酸酯组合物中POS / SOS比为2-12，POS含量为30-55重量％。根据本发明的脂肪组合物具有与具有高POS含量的可可脂类似的甘油三酸酯组合物，从而显示具有特定于可可脂的陡峭斜率的固体脂肪含量（SFC）曲线，并且因此在口中更加融化并且可以用作当食用时具有非硬而柔软感的可可脂当量。此外，本发明的脂肪组合物相对于商业可可脂代用品具有优异的耐花性。

4. 发明申请

WO2011043582A2 BURNER AND AFTERTREATING DEVICE OF EXHASUT GAS 审中-公开
标题翻译：燃烧器和排气的后处理装置
公开(公告)号：WO2011043582A2
公开(公告)日：2011-04-14
申请号：PCT/KR2010006815
申请日：2010-10-06
申请人： SK INNOVATION CO LTD , KIM YOUNG SHOL , LEE WOO JIN , PARK HAE JIN , JUNG HONG SEOK , KIM YUN SIK
发明人： KIM YOUNG SHOL , LEE WOO JIN , PARK HAE JIN , JUNG HONG SEOK , KIM YUN SIK
IPC分类号： F01N3/00 , F01N3/025 , F01N3/24 , F01N3/38
CPC分类号： F01N3/36 , F01N3/035 , F01N3/38 , F01N2240/14
摘要： Provided are a burner and an aftertreating device of exhaust gas, which employs a simple construction using the flame protection tube, thereby increasing stability in forming the flame without the loss of back pressure and also uniformly heating the exhaust gas.
摘要翻译：本发明提供一种废气的燃烧器和后处理装置，其采用使用阻燃管的简单结构，从而提高形成火焰时的稳定性而不会损失背压并且也均匀地加热废气。

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