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    • 3. 发明申请
    • PREPARING METHOD FOR (S)-3-HYDROXYBUTYRIC ACID AND (S)-3-HYDROXYBUTYRATE ESTER USING RECOMBINANT MICROORGANISM
    • (S)-3-羟基丁酸和(S)-3-羟基丁酸酯的制备方法使用重组微生物
    • WO2009020279A1
    • 2009-02-12
    • PCT/KR2008/003217
    • 2008-06-10
    • LG CHEM, LTD.PARK, Si JaeLEE, Sang Hyun
    • PARK, Si JaeLEE, Sang Hyun
    • C12N15/66
    • C12P7/62C12P7/42
    • A method of synthesizing optically-active (S)-3-hydroxybutyric acid and (S)-3-hydroxybutyrate ester using a mutated microorganism is provided. More particularly, a mutated microorganism for preparing (S)-3-hydroxybutyric acid transformed with a gene encoding β-ketothiolase, a gene encoding (S)-3- hydroxybutyryl CoA dehydrogenase and a gene encoding acyl CoA hydrolase; a method of preparing (S)-3-hydroxybutyric acid using the mutated microorganism; a mutated microorganism for preparing (S)-3-hydroxybutyrate ester transformed with a gene encoding β-ketothiolase, a gene encoding (S)- 3-hydroxybutyryl CoA dehydrogenase, a gene encoding acyl CoA hydrolase and a gene encoding lipase; and a method of preparing (S)-3-hydroxybutyrate ester using the mutated microorganism are provided. Accordingly, (S)-3-hydroxybutyric acid with high optical purity may be produced from acetyl CoA produced in glycolysis of a microorganism by a simple process involving the manipulation of a metabolic pathway by a recombinant gene introduced into the microorganism without using a high-cost metal catalyst or a substrate. Further, (S)-3-hydroxybutyrate ester and lactone of (S)-3-hydroxybutyrate ester may be simply produced from (S)-3- hydroxybutyric acid produced by the above method using lipase.
    • 提供了使用突变微生物合成光学活性(S)-3-羟基丁酸和(S)-3-羟基丁酸酯的方法。 更具体地,涉及用编码β-酮硫解酶的基因,编码(S)-3-羟基丁酰辅酶A脱氢酶的基因和编码酰基辅酶A水解酶的基因转化的(S)-3-羟基丁酸的突变微生物; 使用突变的微生物制备(S)-3-羟基丁酸的方法; 用于制备用编码β-酮硫解酶的基因,编码(S)-3-羟基丁酰辅酶A脱氢酶的基因,编码酰基辅酶A水解酶的基因和编码脂肪酶的基因转化的(S)-3-羟基丁酸酯的突变微生物; 并提供使用突变微生物制备(S)-3-羟基丁酸酯的方法。 因此,具有高光学纯度的(S)-3-羟基丁酸可以通过涉及通过引入微生物的重组基因操纵代谢途径的简单方法由乙醇辅酶A生产的乙酰辅酶A产生, 成本金属催化剂或基材。 此外,(S)-3-羟基丁酸酯的(S)-3-羟基丁酸酯和内酯可以由使用脂肪酶的上述方法制备的(S)-3-羟基丁酸简单地制备。
    • 5. 发明申请
    • LDPC ENCODER AND DECODER AND LDPC ENCODING AND DECODING METHODS
    • LDPC编码器和解码器和LDPC编码和解码方法
    • WO2006062351A1
    • 2006-06-15
    • PCT/KR2005/004177
    • 2005-12-07
    • ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTELEE, Sang HyunAHN, Jae Young
    • LEE, Sang HyunAHN, Jae Young
    • H03M13/11
    • H03M13/1168H03M13/116H03M13/118H03M13/616H03M13/6356H03M13/6516
    • Provided are an LDPC encoder and decoder, and LDPC encoding and decoding methods. The LDPC encoder includes: a code generating circuit that includes a memory storing a first parity check matrix and sums a first row which is at least one row of the first parity check matrix and a second row which is at least one of the remaining rows of the first parity check matrix to output a second parity check matrix; and an encoding circuit receiving the second parity check matrix and an information word to output an LDPC-encoded code word. Also the LDPC decoder includes: a code generating circuit including a memory which stores a first parity check matrix and summing a first row which is at least one row of the first parity check matrix and a second row which is at least one of the remaining rows of the first parity check matrix to output a second parity check matrix; and a decoding circuit receiving the second parity check matrix and a code word to output an LDPC-decoded information word.
    • 提供了一种LDPC编码器和解码器,以及LDPC编码和解码方法。 LDPC编码器包括:代码生成电路,其包括存储第一奇偶校验矩阵的存储器,并且对作为第一奇偶校验矩阵的至少一行的第一行和与作为第一奇偶校验矩阵的剩余行中的至少一行的第二行求和 所述第一奇偶校验矩阵输出第二奇偶校验矩阵; 以及接收第二奇偶校验矩阵的编码电路和输出LDPC编码码字的信息字。 此外,LDPC解码器包括:代码生成电路,包括存储器,存储第一奇偶校验矩阵并对作为第一奇偶校验矩阵的至少一行的第一行求和作为剩余行中的至少一个的第二行 的第一奇偶校验矩阵以输出第二奇偶校验矩阵; 以及接收第二奇偶校验矩阵的解码电路和输出LDPC解码信息字的码字。