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1. 发明申请

WO2012115464A2 COMPOSITION FOR HOT-START PCR COMPRISING BLOCKING OLIGONUCLEOTIDE 审中-公开
标题翻译：包含阻断寡核苷酸的热启动PCR组合物
公开(公告)号：WO2012115464A2
公开(公告)日：2012-08-30
申请号：PCT/KR2012001387
申请日：2012-02-23
申请人： BIONEER CORP , LEE JUN HEE , CHOI SO RA , KIM NAM IL , PARK HAN OH
发明人： LEE JUN HEE , CHOI SO RA , KIM NAM IL , PARK HAN OH
IPC分类号： C12Q1/68 , C12N15/11 , C12Q1/48
CPC分类号： C12Q1/686 , C12Q1/6848 , C12Q2527/107 , C12Q2537/161 , C12Q2537/163 , C12Q2549/101 , C12Q2525/204 , C12Q2525/186
摘要： The present invention relates to a composition for hot-start PCR, more precisely a composition for hot-start PCR characteristically prepared by adding the blocking oligonucleotide having the hydroxyl group at 3'-end blocked and the nucleotide sequence complementary to the primer to the conventional PCR composition containing reaction buffer, MgCl2, 4 kinds of dNTP, and DNA polymerase. The composition for hot-start PCR of the present invention can give more authentic PCR results by inhibiting smear band of PCR amplification product caused by non-specific reaction or primer-dimer formation at low temperature since the blocking oligonucleotide included therein can be dissociated at the lower temperature than melting temperature of the primer.
摘要翻译：本发明涉及用于热启动PCR的组合物，更确切地说是一种用于热启动PCR的组合物，其特征在于通过将3'末端具有羟基的封闭寡核苷酸添加到与常规引物互补的核苷酸序列含有反应缓冲液，MgCl 2，4种dNTP和DNA聚合酶的PCR组合物。本发明的热启动PCR用组合物通过在低温下抑制非特异性反应或引物二聚体形成引起的PCR扩增产物的涂片带，可以得到更加真实的PCR结果，因为其中包含的封闭寡核苷酸可以在低于底漆的熔化温度。

2. 发明申请

WO2010120060A3 TONER FOR DEVELOPING AN ELECTROSTATIC IMAGE 审中-公开
标题翻译：用于开发静电图像的调色剂
公开(公告)号：WO2010120060A3
公开(公告)日：2010-12-23
申请号：PCT/KR2010002093
申请日：2010-04-06
申请人： SAMSUNG FINE CHEMICALS CO LTD , HWANG IL SUN , HWANG DAE IL , LEE JUN HEE , CHOI DAE WOONG , KIM YUN NA
发明人： HWANG IL SUN , HWANG DAE IL , LEE JUN HEE , CHOI DAE WOONG , KIM YUN NA
IPC分类号： G03G9/08
CPC分类号： G03G9/0827 , G03G9/0821 , G03G9/08755 , G03G9/08791 , G03G9/08795
摘要： The present invention provides a toner which has enhanced high temperature storage stability and which prevents the degradation of the charging properties thereof caused by moisture absorption. The toner has a particle volume mean diameter within the range of 2 to 10µm, and an 80% span value of 0.9 or less, and comprises a binder resin and a colorant. The binder resin is a sulfonic acid group-free polyester resin having a weight-average molecular weight of 6,000 to 100,000, a glass transition temperature of 55°C to 70°C, and a polydipersity index (Mw/Mn) of 3 to 25.
摘要翻译：本发明提供一种调色剂，其具有高的储存稳定性，并且防止由吸湿引起的带电性能的劣化。调色剂的颗粒体积平均直径在2至10μm的范围内，并且80％跨度值为0.9或更小，并且包含粘合剂树脂和着色剂。粘合剂树脂是重均分子量为6000〜100,000，玻璃化转变温度为55℃〜70℃，聚阴离子指数（Mw / Mn）为3〜25的无磺酸基的聚酯树脂。

3. 发明授权

KR101164225B1 Velvet woven fabric of high density 有权
标题翻译：高密度的VELVET WOVEN织物
公开(公告)号：KR101164225B1
公开(公告)日：2012-07-10
申请号：KR20120031890
申请日：2012-03-28
申请人： LEE JUN HEE
发明人： LEE JUN HEE
IPC分类号： D03D27/12 , D03D15/00
摘要： PURPOSE: A velvet fabric of high density is provided to ensure constant pile length and to ensure excellent luster, soft, and beauty properties. CONSTITUTION: A velvet fabric is woven by selectively connecting a bottom and piles by a longitudinal driving device of cam and dobby types. The fineness of the pile is more than 135 deniers. The number of filament is more than 34. The KOSHI value of the velvet fabric is more than 3.5. The pile is formed of acetate.
摘要翻译：目的：提供高密度的天鹅绒织物，以确保绒头长度不变，并确保优异的光泽，柔软和美观。构成：通过用凸轮和多臂式纵向驱动装置选择性地连接底部和桩来编织天鹅绒织物。堆的细度超过135旦。长丝数超过34.天鹅绒面料的KOSHI值超过3.5。该堆由醋酸盐形成。

4. 发明申请

WO2012011707A3 SUBSTITUTED PYRIDINONE DERIVATIVES AND METHODS FOR MANUFACTURING THE SAME 审中-公开
标题翻译：取代的吡啶酮衍生物及其制备方法
公开(公告)号：WO2012011707A3
公开(公告)日：2012-05-31
申请号：PCT/KR2011005268
申请日：2011-07-18
申请人： HYUNDAI PHARM CO LTD , PARK YONG KYU , BANG SUNG HUN , KIM JIN WOONG , LEE HAN KYU , KIM JAE HYUN , SON CHANG MO , LEE JUN HEE , SHIN CHANG YONG , LEE JONG CHAN , RHEE JAE KEOL
发明人： PARK YONG KYU , BANG SUNG HUN , KIM JIN WOONG , LEE HAN KYU , KIM JAE HYUN , SON CHANG MO , LEE JUN HEE , SHIN CHANG YONG , LEE JONG CHAN , RHEE JAE KEOL
IPC分类号： C07D401/14 , A61K31/444 , A61P3/00 , C07D401/12
CPC分类号： C07D401/14 , C07D213/69 , C07D213/70 , C07D401/12 , C07D413/12
摘要： Disclosed are a novel compound or a pharmaceutically acceptable salt thereof, a preparation method thereof, and the compound-containing pharmaceutical composition for treating a metabolic disorder. Specifically, the disclosed compound is represented by [Formula 1]. The compound activates GPR119, and thus can be used for treating metabolic disorders, that is, diabetes mellitus, diabetes mellitus-related diseases, diabetes mellitus-related microvessel complications, diabetes mellitus-related large vessel complications, cardiovascular disorders, metabolic syndrome and its constituent diseases, obesity, and other diseases. In Formula 1, P1, P2, P3, P4, L1, R4, n4, X, Y, Z1 and Z2 are the same as defined above.
摘要翻译：公开了一种新型化合物或其药学上可接受的盐，其制备方法和用于治疗代谢紊乱的含化合物的药物组合物。具体地，所公开的化合物由[式1]表示。该化合物可激活GPR119，因此可用于治疗代谢性疾病，即糖尿病，糖尿病相关疾病，糖尿病相关性微血管并发症，糖尿病相关大血管并发症，心血管疾病，代谢综合征及其成分疾病，肥胖等疾病。在式1中，P1，P2，P3，P4，L1，R4，n4，X，Y，Z1和Z2与上述相同。

5. 发明申请

WO2010120059A2 METHOD FOR PRODUCING A TONER 审中-公开
标题翻译：生产调色剂的方法
公开(公告)号：WO2010120059A2
公开(公告)日：2010-10-21
申请号：PCT/KR2010002092
申请日：2010-04-06
申请人： SAMSUNG FINE CHEMICALS CO LTD , HWANG IL SUN , HWANG DAE IL , LEE JUN HEE , CHOI DAE WOONG , KIM YUN NA , SHIM SANG EUN
发明人： HWANG IL SUN , HWANG DAE IL , LEE JUN HEE , CHOI DAE WOONG , KIM YUN NA , SHIM SANG EUN
IPC分类号： G03G9/08
CPC分类号： G03G9/08755 , G03G9/0804 , G03G9/0806 , G03G9/0819 , G03G9/08791
摘要： Disclosed is a method for producing a toner. The method for producing a toner according to the present invention involves using sulfonic acid group-free polyester, and producing toner particles from an aqueous medium having no organic solvent, to thereby obtain toner particles with narrow particle size distribution and excellent conservation properties.
摘要翻译：公开了一种用于制造调色剂的方法。根据本发明的调色剂的制造方法涉及使用不含磺酸基的聚酯，并且由不含有机溶剂的水性介质制造调色剂颗粒，从而获得具有窄粒度分布和优异保存性能的调色剂颗粒。

6. 发明申请

WO2011025329A2 DETECTING METHODS OF DNA AMPLIFICATION USING NEW INTERCALATING AGENT 审中-公开
标题翻译：用新的内标剂检测DNA扩增的方法
公开(公告)号：WO2011025329A2
公开(公告)日：2011-03-03
申请号：PCT/KR2010005840
申请日：2010-08-30
申请人： BIONEER CORP , LEE JUN HEE , PARK HWANG SEO , HAN EUN SU , LEE JAE DON , PARK HAN OH
发明人： LEE JUN HEE , PARK HWANG SEO , HAN EUN SU , LEE JAE DON , PARK HAN OH
IPC分类号： C09K11/06
CPC分类号： C09K11/06 , C09K2211/1007 , C09K2211/1011 , C09K2211/1014 , C09K2211/1029 , C09K2211/1037 , C12Q1/6841 , G01N1/30 , C12Q2565/629 , C12Q2565/631
摘要： Disclosed are a fluorescent composition for staining DNA and a method for measuring DNA amplification using the same. More particularly, disclosed are a novel fluorescent compound that emits light by intercalating with DNA and a method for measuring DNA amplification using the same. The novel fluorescent compound is advantageous in that, due to high sensitivity, target-specific amplification products by real-time polymerase chain reaction(PCR) can be accurately quantified without affecting the PCR reaction. In addition, the compound is unharmful to the human body, can be prepared at low cost, and allows monitoring of various DNA and RNA reactions in vitro or in vivo.
摘要翻译：公开了用于染色DNA的荧光组合物和使用其的DNA扩增测量方法。更具体地说，公开了通过插入DNA而发光的新型荧光化合物和使用其测量DNA扩增的方法。该新型荧光化合物的优点在于，由于高灵敏度，通过实时聚合酶链反应（PCR）的目标特异性扩增产物可以准确定量而不影响PCR反应。此外，该化合物对人体无害，可以以低成本制备，并且允许在体外或体内监测各种DNA和RNA反应。

7. 发明申请

WO2010018458A3 PHENOL DERIVATIVES AS HIF-ALPHA MODULATORS 审中-公开
标题翻译：酚醛衍生物作为HIF-ALPHA调节剂
公开(公告)号：WO2010018458A3
公开(公告)日：2010-04-08
申请号：PCT/IB2009006751
申请日：2009-08-12
申请人： CRYSTALGENOMICS INC , HONG YONG RAE , SHIN DONGKYU , RO SEONGGU , CHO JOONG MYUNG , KIM HYUN TAE , LEE JUN HEE , KIM JEONG MI , LEE WHEE SEONG , CHOI JONG-RYOO
发明人： HONG YONG RAE , SHIN DONGKYU , RO SEONGGU , CHO JOONG MYUNG , KIM HYUN TAE , LEE JUN HEE , KIM JEONG MI , LEE WHEE SEONG , CHOI JONG-RYOO
IPC分类号： C07D213/63 , C07D215/20 , C07D401/04
CPC分类号： C07D213/63 , C07D213/79 , C07D215/20 , C07D233/22 , C07D263/14 , C07D277/14 , C07D277/56 , C07D401/04 , C07D401/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14
摘要： Disclosed herein are hydroxyaryl or hydroxyheteroaryl derivative compounds, or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, pharmaceutical compositions comprising the same, and methods of modulating the level or activity of HIF in a subject, inhibiting hydroxylation of HIFa in a subject, modulating expression of HIF-regulated genes in a subject, treating an HIF -related disorder in a subject, increasing levels of endogenous EPO in a subject, or treating a disorder in a subject, using the disclosed compounds.
摘要翻译：本文公开的是羟基芳基或羟基杂芳基衍生物化合物或其药学上可接受的盐，酯，酰胺或前药，包含其的药物组合物和调节受试者中HIF水平或活性的方法，抑制受试者中HIFa的羟化调节受试者中HIF调节基因的表达，使用所公开的化合物治疗受试者中HIF相关病症，增加受试者内源性EPO的水平或治疗受试者的病症。

8. 发明公开

KR20120053400A Rotary muti-tap 审中-公开
标题翻译：旋转MUTI-TAP
公开(公告)号：KR20120053400A
公开(公告)日：2012-05-25
申请号：KR20100114649
申请日：2010-11-17
申请人： LEE JUN HEE
发明人： LEE JUN HEE
IPC分类号： H01R13/66 , H01R35/04
摘要： PURPOSE: A rotary multi-tap is provided to smoothly perform combining processes of monomers and a metal power source line. CONSTITUTION: Two metal power lines(20) are respectively formed on a monomer. A protrusion part(30) is formed in one side of the monomer. A guide barrier groove(31) is formed along the side boundary of the protrusion part. A groove part(40) is formed on the adjacent other side of the monomer. A plurality of protrusions(41) is formed the inner side boundary of the groove part. A protrusion part(22) is formed on one side of the metal power line. A guide groove(21b) is formed inside the metal power line. A fixing part(21) is formed on an inner side surface of the metal power line.
摘要翻译：目的：提供旋转式多分接头，以顺利进行单体和金属电源线的组合过程。构成：在单体上分别形成两根金属电源线（20）。突起部（30）形成在单体的一侧。沿突出部分的边界形成导向阻挡槽（31）。在单体的相邻的另一侧上形成有槽部（40）。多个突起（41）形成在槽部的内侧边界。突出部（22）形成在金属电源线的一侧。导向槽（21b）形成在金属电源线内部。固定部分（21）形成在金属电源线的内侧表面上。

9. 发明公开

KR20120028957A Velvet loom, connection way of heald and cam, dobby way running gear 审中-公开
标题翻译： VELVET LOOM，连接方式的健康和CAM，DOBBY方式运行齿轮
公开(公告)号：KR20120028957A
公开(公告)日：2012-03-23
申请号：KR20120018030
申请日：2012-02-22
申请人： LEE JUN HEE
发明人： LEE JUN HEE
IPC分类号： D03C5/00 , D03C1/00 , D03C5/02
CPC分类号： D03C1/00 , D03C5/02 , D03C9/0683
摘要： PURPOSE: A method for connecting a heald, a cam, and a driving device in a velvet loom is provided to obtain velvet fabrics with various forms. CONSTITUTION: A method for connecting a heald, a cam, and a driving device of dobby type comprises a step of randomly connecting a heald for paper bottom and heald for a velvet with wires(200)(201) in a velvet loom. The heald for paper bottom is connected with the heald for the velvet by wire forming the driving device of dobby type.
摘要翻译：目的：提供一种在天鹅绒织机中连接综丝，凸轮和驱动装置的方法，以获得各种形式的天鹅绒织物。构成：用于连接多by类型的综丝，凸轮和驱动装置的方法包括在天鹅绒织机中随机连接用于纸底的综丝用于天鹅绒与丝线（200）（201）的步骤。纸底的综框通过线形成多臂式驱动装置与天鹅绒的综框连接。

10. 发明公开

KR20180054245A 나선형 고체부상 패들을 이용한 오염 토양 정화를 위한 전기분해 장치 审中-公开
公开(公告)号：KR20180054245A
公开(公告)日：2018-05-24
申请号：KR20160151943
申请日：2016-11-15
申请人： LEE JUN HEE , LEE SAE MI , LEE SEUNG CHEOL
发明人： LEE JUN HEE , LEE SEUNG CHEOL , LEE SAE MI
IPC分类号： B01F7/18 , B01F15/00 , B09C1/08
摘要： 본발명은오염토양및 산업부산물이함유한유기물, 중금속, 염화물등을처리하여인체에미치는영향을최소화하고, 정화된토양을재활용할수 있도록하는나선형고체부상패들및 이를이용한오염토양정화를위한전기분해장치를제공한다. 본발명은액상뿐만아니라고상까지혼합이가능하여다양한성상의혼합유체에적용가능하고, 전기분해반응을효과적으로증대시키며, 토양의효과적부상및 분산으로전원공급장치의전력부하를감소시키고, 공정의유연성을증대시킬수 있는효과가있다. 또한, 패들을나선형으로구성함으로써모터의구동으로회전축이회전함에따라나선형에서발생하는고체부상효과로강제와류가일어나혼합유체의고체와액체가균일하게혼합하도록하여혼합효과를더욱증대시킬수 있는효과가있다. 또한, 토양전기분해장치를구성하는구성요소들이단순결합형태로구성되어있어파손등에따른교체시용이하게구성요소를교체할수 있고, 분리가용이하기때문에청소및 세척이용이한효과가있다.

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