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1. 发明授权

US10654788B2 Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid 有权
公开(公告)号：US10654788B2
公开(公告)日：2020-05-19
申请号：US15557717
申请日：2016-03-14
申请人： L'OREAL
发明人： Maria Dalko , Xavier Marat , Julien Hitce , Chao-Jun Li
IPC分类号： C07C59/11 , C07C51/38 , C07C69/675 , C07C45/54 , C07C67/347 , C07C69/757 , C07C69/732 , C07C69/734 , C07C45/69 , A61K8/365 , A61Q17/00 , A61Q19/00 , C07C51/09 , C07C59/54 , C07C59/56 , C07C59/72
摘要： The present invention relates to compounds of formula (I): in which R1 is a hydrogen atom, a phenyl radical, or a straight or branched, saturated or unsaturated hydrocarbon radical having 1 to 8 carbon atoms.

2. 发明授权

US11166895B2 Hair care compositions comprising thiolactic acid-based ionic liquids or thiolactic acid-based ionic mixtures 有权
公开(公告)号：US11166895B2
公开(公告)日：2021-11-09
申请号：US16331568
申请日：2017-10-02
申请人： L'OREAL
发明人： Ronak Rughani , Magali Moreau , Julien Hitce , Maria Dalko , Alexandre Cavezza , Christian Blaise , Robin D. Rogers , Giovanni Pietro Rachiero , Gabriela Gurau
IPC分类号： A61K8/46 , A61K8/41 , A61Q5/02 , A61Q5/04 , A61Q5/06 , A61Q5/12
摘要： The instant disclosure relates hair care compositions comprising ionic liquids or ionic mixtures. Ionic liquids or ionic mixtures are combined with a cosmetically acceptable carrier to form ready-to-use hair care compositions. The ionic liquids and the ionic mixtures are formed from; (1) thiolactic acid and/or one or more alkali metal or alkaline earth metal salts thereof; and (2) one or more amine compounds, and/or one or more ammonium cationic compounds, and/or one or more salts thereof. The ionic liquids, the ionic mixtures, and the hair care compositions comprising the ionic liquids or the ionic mixtures, are useful in methods for preventing hair damage, shaping hair, caring for hair, etc.

3. 发明授权

US11318079B2 Polyhydroxylated (1-phenyl-2-phenyl) ethylene derivatives as an anti-ageing and photoprotective agent 有权
公开(公告)号：US11318079B2
公开(公告)日：2022-05-03
申请号：US15576555
申请日：2016-05-27
申请人： L'OREAL
发明人： Julien Hitce
IPC分类号： A61K8/37 , A61K8/34 , A61Q19/08 , A61K8/33 , A61Q17/04
摘要： The present invention is directed towards the cosmetic use of at least one compound of formula (I) and/or solvates thereof and/or stereoisomers thereof: in which groups A and B are different and: A-* represents a disubstituted phenyl radical: B-** represents a mono- or disubstituted phenyl radical: or of a composition comprising, in a physiologically acceptable medium, at least one compound of formula (I), for treating and/or preventing the signs of ageing and/or of photoageing of keratin materials, preferably of the skin.

4. 发明授权

US10307353B2 1-phenylmono- or -polyhydroxypropane compounds, compositions and cosmetic uses thereof 有权
公开(公告)号：US10307353B2
公开(公告)日：2019-06-04
申请号：US15534190
申请日：2015-12-11
申请人： L'OREAL
发明人： Maria Dalko , Julien Hitce
IPC分类号： A61K8/34 , A61Q19/08 , C07C43/23 , A61K31/085 , A61K31/09
摘要： The present invention relates to novel compounds of formula (I) to compositions comprising same, and also to the use thereof for preventing and/or cosmetically treating the signs of aging of the skin.

5. 发明授权

US10144690B2 1,2-diphenylethylene glycol compounds for combating aging of the skin, and cosmetic use thereof 有权
公开(公告)号：US10144690B2
公开(公告)日：2018-12-04
申请号：US15534174
申请日：2015-12-11
申请人： L'OREAL
发明人： Julien Hitce
IPC分类号： A61K8/34 , A61Q19/08 , C07C39/15 , C07C43/23
摘要： The present invention relates to novel compounds of formula (I) to cosmetic compositions comprising same, and also to the use thereof for preventing and/or cosmetically treating the signs of aging of the skin.

6. 发明授权

US10357440B2 Composition comprising at least one 2-(3,4-disubstituted)phenyl-1-(3,4-disubstituted)phenyl-1-hydroxyethane for preventing and/or treating the signs of ageing of the skin 有权
公开(公告)号：US10357440B2
公开(公告)日：2019-07-23
申请号：US15538988
申请日：2015-12-21
申请人： L'OREAL
发明人： Julien Hitce , Maria Dalko , Marie-Céline Frantz
IPC分类号： A61K31/05 , A61K8/34 , A61K8/33 , A61Q19/08 , C07C43/23
摘要： The present invention relates to the cosmetic use, in a composition containing a physiologically acceptable medium, of at least one compound of formula (I) in which: —R3 means a hydrogen atom or a hydroxyl radical, —R1 and R2 mean, independently of each other, a hydrogen atom, a linear or branched C1-C6 alkyl radical; a benzyl radical; a linear or branched C1-C6 alkylcarbonyl radical not conjugated with the carbonyl; or a linear or branched C1-C6 alkoxycarbonyl radical, and/or of an isomer and/or of a salt and/or of a solvate of said compound of formula (1), for preventing and/or treating the signs of ageing of the skin and its appendages.

7. 发明授权

US09833397B2 Anti-dandruff sugars 有权
公开(公告)号：US09833397B2
公开(公告)日：2017-12-05
申请号：US14429793
申请日：2013-09-19
申请人： L'OREAL
发明人： Maria Dalko , Julien Hitce , Laure Ramos-Stanbury
IPC分类号： A61K8/60 , A61Q5/00 , C07H15/04 , C07H15/10 , A61Q5/02
CPC分类号： A61K8/602 , A61Q5/006 , A61Q5/02 , C07H15/04 , C07H15/10
摘要： The invention relates to the cosmetic use of at least one compounds according to the following formula (I), as an anti-dandruff agent or for preventing and/or treating scalp dandruff: where “sugar” denotes a monosaccharide residue chosen from rhamnose, xylose, fucose, mannose, lyxose, and arabinose; where R, substituting the anomeric oxygen in the sugar (represented by “O” in formula (I)), denotes a radical comprising 6 to 38 carbon atoms chosen from: —a linear or branched, saturated alkyl radical; —a linear or branched, alkenyl radical; said linear or branched saturated alkyl radical being optionally substituted by at least one OH and/or NH2 function; —if “sugar” denotes a mannose residue, R denotes a linear C6-C38 alkyl radical, substituted by at least one OH function or an NH2 function; and the salts and solvates and/or optical isomers thereof, alone or in a mixture, particularly racemic forms. The invention also relates to compounds according to formula (I), and cosmetic compositions containing same.

8. 发明申请

US20150250698A1 ANTI-DANDRUFF SUGARS 有权
标题翻译：抗糖甘蔗糖
公开(公告)号：US20150250698A1
公开(公告)日：2015-09-10
申请号：US14429793
申请日：2013-09-19
申请人： L'OREAL
发明人： Maria Dalko , Julien Hitce , Laure Ramos-Stanbury
IPC分类号： A61K8/60 , C07H15/10 , A61Q5/00 , C07H15/04
CPC分类号： A61K8/602 , A61Q5/006 , A61Q5/02 , C07H15/04 , C07H15/10
摘要： The invention relates to the cosmetic use of at least one compounds according to the following formula (I), as an anti-dandruff agent or for preventing and/or treating scalp dandruff: where “sugar” denotes a monosaccharide residue chosen from rhamnose, xylose, fucose, mannose, lyxose, and arabinose; where R, substituting the anomeric oxygen in the sugar (represented by “O” in formula (I)), denotes a radical comprising 6 to 38 carbon atoms chosen from: —a linear or branched, saturated alkyl radical; —a linear or branched, alkenyl radical; said linear or branched saturated alkyl radical being optionally substituted by at least one OH and/or NH2 function; —if “sugar” denotes a mannose residue, R denotes a linear C6-C38 alkyl radical, substituted by at least one OH function or an NH2 function; and the salts and solvates and/or optical isomers thereof, alone or in a mixture, particularly racemic forms. The invention also relates to compounds according to formula (I), and cosmetic compositions containing same.
摘要翻译：本发明涉及至少一种根据下式（I）的化合物作为抗头皮屑剂或用于预防和/或治疗头皮头皮屑的化妆用途：其中“糖”表示选自鼠李糖，木糖的单糖残基，岩藻糖，甘露糖，lyxose和阿拉伯糖; 其中R代替糖中的异头氧（在式（I）中由“O”表示））表示选自：直链或支链饱和烷基的6至38个碳原子的基团; - 直链或支链烯基; 所述直链或支链饱和烷基任选被至少一个OH和/或NH 2官能团取代; -if“糖”表示甘露糖残基，R表示被至少一个OH官能团或NH 2官能团取代的直链C 6 -C 38烷基; 及其盐和溶剂化物和/或光学异构体，单独或混合物，特别是外消旋形式。本发明还涉及式（I）化合物和含有它的化妆品组合物。

9. 发明授权

US10995051B2 Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid 有权
公开(公告)号：US10995051B2
公开(公告)日：2021-05-04
申请号：US16731705
申请日：2019-12-31
申请人： L'OREAL
发明人： Maria Dalko , Xavier Marat , Julien Hitce , Chao-Jun Li
IPC分类号： C07C45/69 , C07C59/11 , C07C51/38 , C07C69/675 , C07C45/54 , C07C67/347 , C07C69/757 , C07C69/732 , C07C69/734 , C07D213/30 , A61K8/365 , A61Q17/00 , A61Q19/00 , C07C51/09 , C07C59/54 , C07C59/56 , C07C59/72
摘要： The present invention relates to compounds of formula (I): in which R1 is a hydrogen atom, a phenyl radical, or a straight or branched, saturated or unsaturated hydrocarbon radical having 1 to 8 carbon atoms.

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