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1. 发明专利

JP2006138656A Molecular imprint gel, its manufacturing method, measuring method for object molecule in specimen using molecular imprint gel, and reagent for object molecule measurement 审中-公开
标题翻译：分子印迹凝胶，其制造方法，使用分子印迹凝胶的样品中对象分子的测量方法和用于对象分子测量的试剂
公开(公告)号：JP2006138656A
公开(公告)日：2006-06-01
申请号：JP2004326321
申请日：2004-11-10
申请人： Kyowa Medex Co Ltd , Univ Kansai , 協和メデックス株式会社 , 学校法人関西大学
发明人： MIYATA TAKASHI , URAGAMI TADASHI
IPC分类号： G01N33/544 , G01N33/53 , G01N33/566
摘要： PROBLEM TO BE SOLVED: To provide a simply manufactured molecular imprint gel for measuring object molecules in a specimen with high sensitivity.
SOLUTION: This molecular imprint gel is manufactured through the following processes: (1) a process for separately reacting two or more ligands in respect to the object molecules with a monomer or polymer serving as a material for the gel to manufacture ligand-introduced monomers or ligand-introduced polymers corresponding to the number of ligands, (2) a process for reacting all the ligands of the introduced-monomers or introduced-polymers manufactured through the process (1) with the object molecules to form a complex of these with the object molecules, (3) a process for forming a high-polymer network by reacting the complex manufactured through the process (2) with a molecular cross-linker to manufacture a gel including the complex of the ligands with the object molecules, and (4) a process for removing the object molecules from the gel manufactured through the process (3).
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供用于以高灵敏度测量样品中的物体分子的简单制造的分子印迹凝胶。解决方案：该分子印迹凝胶通过以下方法制备：（1）将两种或多种配体相对于目标分子与单体或聚合物分开反应的方法，该单体或聚合物用作凝胶的材料以制备配体 - 引入对应于配体数量的单体或配体引入的聚合物，（2）使通过方法（1）制备的引入单体或引入的聚合物的所有配体与对象分子反应以形成这些的复合物的方法（3）通过使通过方法（2）制备的络合物与分子交联剂反应形成高聚物网络的方法，以制备包含配体与物体分子的络合物的凝胶，以及（4）通过方法（3）从制造的凝胶中除去目标分子的方法。版权所有（C）2006，JPO＆NCIPI

2. 发明专利

JP2007244374A Nucleic acid-responsive gel, method for producing the same and use thereof 有权
标题翻译：核酸反应性凝胶，其生产方法及其用途
公开(公告)号：JP2007244374A
公开(公告)日：2007-09-27
申请号：JP2007005227
申请日：2007-01-12
申请人： Japan Science & Technology Agency , Univ Kansai , 学校法人関西大学 , 独立行政法人科学技術振興機構
发明人： MIYATA TAKASHI , URAGAMI TADASHI , OKAWA KAORI
IPC分类号： C12Q1/68 , C12M1/00 , C12N15/09 , G01N33/53
摘要： PROBLEM TO BE SOLVED: To provide a nucleic acid-responsive gel enabling the improvement of volume change by the structure design, regulating the recognition activity of nucleic acid, having improved sensitivity and easily designable according to the sequence of target DNA, etc. SOLUTION: The nucleic acid-responsive gel contains a probe composed of a pair of hybridized single-stranded nucleic acids fixed in the network structure of a polymer gel. Two single stranded nucleic acids are reversibly bonded in the probe. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供能够通过结构设计改善体积变化的核酸响应性凝胶，调节核酸的识别活性，具有改善的灵敏度并且可以根据目标DNA的顺序容易地设计等解决方案：核酸反应性凝胶包含由固定在聚合物凝胶的网络结构中的一对杂交的单链核酸组成的探针。两个单链核酸在探针中可逆结合。版权所有（C）2007，JPO＆INPIT

3. 发明专利

JP2009261334A Nucleic acid-responsible gel, method for producing the same and utilization thereof 有权
标题翻译：核酸凝胶，其生产方法及其利用方法
公开(公告)号：JP2009261334A
公开(公告)日：2009-11-12
申请号：JP2008116058
申请日：2008-04-25
申请人： Japan Science & Technology Agency , Univ Kansai , 学校法人関西大学 , 独立行政法人科学技術振興機構
发明人： MIYATA TAKASHI , URAGAMI TADASHI
IPC分类号： C12N15/09 , C12M1/00 , C12M1/34 , C12Q1/68 , G01N33/53 , G01N33/543 , G01N33/548
摘要： PROBLEM TO BE SOLVED: To achieve a nucleic acid-responsible gel not only being swollen or shrunk in the presence of a target nucleic acid but also enabling the nucleic acid to be detected by a simple method. SOLUTION: The nucleic acid-responsible gel is obtained by immobilizing a probe comprising hybridized two single-stranded nucleic acids in a network structure of a polymer gel. In the probe, the two single-stranded nucleic acids are reversibly bonded, and the two single-stranded nucleic acids comprise a single-stranded nucleic acid into which a fluorescent donor molecule is introduced, and a single-stranded nucleic acid into which an acceptor molecule causing fluorescent resonance energy transfer with the fluorescent donor molecule is introduced. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：待解决的问题：为了实现核酸负荷凝胶，不仅在目标核酸存在下发生肿胀或收缩，而且能够通过简单的方法检测核酸。解决方案：通过将包含杂交的两个单链核酸的探针固定在聚合物凝胶的网络结构中来获得核酸负责的凝胶。在探针中，两条单链核酸是可逆结合的，并且两条单链核酸包含其中引入荧光供体分子的单链核酸，以及单链核酸，其中受体引入与荧光供体分子进行荧光共振能量转移的分子。版权所有（C）2010，JPO＆INPIT

4. 发明专利

JP2015010219A ハイドロゲル及びその製造方法有权
标题翻译：水凝胶及其制造方法
公开(公告)号：JP2015010219A
公开(公告)日：2015-01-19
申请号：JP2013138964
申请日：2013-07-02
申请人：大塚化学株式会社 , Otsuka Chem Co Ltd , 学校法人関西大学 , Kansai Univ , 学校法人関西大学
发明人： HIROI RYOICHI , ISHITOBI HIROYUKI , MIYATA TAKASHI , KAWAMURA AKIFUMI
IPC分类号： C08F2/10 , C08F220/56 , C08F222/38
摘要：【課題】機械的強度に優れたハイドロゲル及びその製造方法を提供する。【解決手段】単官能性ビニルモノマーと、多官能性ビニルモノマーと、水又は水性溶媒とを含む溶液中で、単官能性ビニルモノマーと、多官能性ビニルモノマーとを、リビングラジカル重合で共重合することにより得られることを特徴とする。【選択図】なし
摘要翻译：要解决的问题：提供具有优异机械强度的水凝胶及其制造方法。溶液：在包含单官能乙烯基单体，多官能乙烯基单体，水或水性溶剂的溶液中，单官能乙烯基单体和多官能乙烯基单体单体通过活性自由基聚合共聚得到本发明的水凝胶。

5. 发明专利

JP2011084526A Method for producing dehydration condensation compound 审中-公开
标题翻译：生产脱水浓缩化合物的方法
公开(公告)号：JP2011084526A
公开(公告)日：2011-04-28
申请号：JP2009239254
申请日：2009-10-16
申请人： Kansai Univ , 学校法人関西大学
发明人： URAGAMI TADASHI , MIYATA TAKASHI
IPC分类号： C07C67/08 , C07B61/00 , C07C41/09 , C07C43/04 , C07C69/14
摘要： PROBLEM TO BE SOLVED: To provide a method for producing a dehydration condensation compound, excellent in reaction conversion rate. SOLUTION: This method for producing the dehydration condensation compound by preparing a reaction composition containing the dehydration condensation compound and water by performing the dehydration condensation reaction in the presence of ionic liquid and a dehydration condensation catalyst includes arranging a hydrophilic water-permeating membrane so that the reaction composition is arranged in one directional side of the membrane and making the pressure on the other directional side lower than the pressure on the reaction composition side of the membrane to reduce the water contained in the reaction composition by permeating the water contained in the reaction composition through the membrane. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供一种反应转化率优异的脱水缩合化合物的制造方法。解决方案：通过在离子液体和脱水缩合催化剂的存在下进行脱水缩合反应制备含有脱水缩合化合物和水的反应组合物的脱水缩合化合物的制造方法包括：配置亲水性透水膜使得反应组合物布置在膜的一个方向侧，并使另一个方向侧的压力低于膜的反应组合物侧的压力，以通过渗透包含在膜中的水来减少反应组合物中所含的水反应组合物通过膜。版权所有（C）2011，JPO＆INPIT

6. 发明专利

JP2011083720A Separative membrane of volatile organic compound and method for separate removing volatile organic compound 有权
标题翻译：挥发性有机化合物的分离膜和单独除去挥发性有机化合物的方法
公开(公告)号：JP2011083720A
公开(公告)日：2011-04-28
申请号：JP2009239258
申请日：2009-10-16
申请人： Kansai Univ , 学校法人関西大学
发明人： URAGAMI TADASHI , MIYATA TAKASHI
IPC分类号： B01D69/00 , B01D61/36 , B01D61/38 , C02F1/44 , C08F20/28
摘要： PROBLEM TO BE SOLVED: To provide a separative membrane, of a volatile organic compound, exhibiting excellent permeability and selective removability, and a method for separate removing the volatile organic compound using the separative membrane of the volatile organic compound.
SOLUTION: The separative membrane of the volatile organic compound is characteristic in that an ionic liquid which dissolves trichloromethane in the volume ratio of ≥1 time or benzene in the volume ratio of ≥1.64 times, is supported by a base material.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供具有优异渗透性和选择性可除去性的挥发性有机化合物的分离膜，以及使用挥发性有机化合物的分离膜分离除去挥发性有机化合物的方法。解决方案：挥发性有机化合物的分离膜的特征在于，以体积比≥1.64倍溶解体积比≥1时的三氯甲烷的离子液体由基材支撑。版权所有（C）2011，JPO＆INPIT

7. 发明专利

JP2014103857A A resin substrate for biomaterial patterning and its manufacturing method, and a material for biomaterial patterning and its manufacturing method 有权
标题翻译：用于生物体材料的树脂基材及其制造方法，以及用于生物材料图案的材料及其制造方法
公开(公告)号：JP2014103857A
公开(公告)日：2014-06-09
申请号：JP2012256965
申请日：2012-11-23
申请人： Kansai Univ , 学校法人関西大学
发明人： MIYATA TAKASHI , KAWAMURA AKIFUMI , KIDA TOMOYUKI
IPC分类号： C12M3/00 , C08J7/12 , C12M1/00
摘要： PROBLEM TO BE SOLVED: To provide a resin base material for biomaterial patterning capable of making without complicated steps such as washing but also patterning two or more types of biomaterials.SOLUTION: On resin substrates 100, 100A for biomaterial patterning related to the present invention, pattern Pn0 and Pn1 are formed by at least 2 types of regions of (a) a first cross-linked region Rc0, Rc1, (b) a second cross-linked region with a different crosslinking degree from that of the first cross-linked region, and (c) uncross-linked region Rn0, Rn1. The cross-linked region may be recessed with respect to the uncross-linked region. On this resin substrate for biomaterial patterning, an uncross-linked region is preferably formed of "a polymeric material mainly including a photopolymerization functional group-containing polymer", and a cross-linked region is preferably formed of "a polymeric material mainly including a photocrosslinking polymer.
摘要翻译：要解决的问题：提供一种用于生物材料图案化的树脂基材，其能够在没有诸如洗涤的复杂步骤的情况下进行，而且还可以对两种或更多种类型的生物材料进行图案化。解决方案：在本发明的用于生物材料图案的树脂基板100,100A上，图案Pn0和Pn1由（a）第一交联区域Rc0，Rc1，（b）与第一交联区域的交联度不同的第二交联区域的至少2种区域形成，（c）未交联区域Rn0，Rn1。交联区域可以相对于未交联区域凹陷。在这种生物材料图案用树脂基板上，未交联区域优选由“主要包含含光聚合官能团的聚合物的聚合物材料”形成，交联区域优选由“主要包含光致交联聚合物。

8. 发明专利

JP2013142098A Asymmetrical porous membrane, method of producing the same, and method of concentrating liquid 审中-公开
标题翻译：非对称多孔膜，其制造方法和浓缩液体的方法
公开(公告)号：JP2013142098A
公开(公告)日：2013-07-22
申请号：JP2012001999
申请日：2012-01-10
申请人： Kansai Univ , 学校法人関西大学
发明人： URAGAMI TADASHI , MIYATA TAKASHI
IPC分类号： C08J9/28 , B01D61/36 , B01D69/12 , B01D71/70 , C08F138/00
摘要： PROBLEM TO BE SOLVED: To provide a permeation-separation membrane capable of improving permeability of ethanol without impairing ethanol selectivity remarkably when concentrating ethanol from an aqueous ethanol solution using an evaporation-permeation method, and a method of production thereof.SOLUTION: An asymmetrical porous membrane includes a resin composition composed mostly of a polymer, the main unit of which is 1-trimethylsilyl-1-propyne. The asymmetrical porous membrane has an open hole. By use of the asymmetrical porous membrane in the evaporation-permeation method, ethanol is concentrated efficiently from the ethanol aqueous solution.
摘要翻译：要解决的问题：提供一种渗透分离膜及其制造方法，其能够在使用蒸发渗透法从乙醇水溶液中浓缩乙醇时，显着提高乙醇的渗透性而不损害乙醇的选择性。膜包括主要由聚合物组成的树脂组合物，其主要单元是1-三甲基甲硅烷基-1-丙炔。不对称多孔膜具有开孔。通过使用蒸发渗透法中的不对称多孔膜，乙醇从乙醇水溶液中有效浓缩。

9. 发明专利

JP2012143188A Method for producing immobilized catalyst membrane, immobilized catalyst membrane and transmembrane reaction method 审中-公开
标题翻译：生产固定化催化剂膜的方法，固定催化剂膜和转化膜反应方法
公开(公告)号：JP2012143188A
公开(公告)日：2012-08-02
申请号：JP2011003862
申请日：2011-01-12
申请人： Kansai Univ , 学校法人関西大学
发明人： URAGAMI TADASHI , MIYATA TAKASHI
IPC分类号： C12N11/02 , B01J31/02 , B01J37/36
摘要： PROBLEM TO BE SOLVED: To provide a method for producing an immobilized catalyst membrane which can produce a homogeneous immobilized enzyme membrane.SOLUTION: The method for producing the immobilized catalyst membrane 100 is provided with a preparation process and a production process. In the preparation process, a first solution is prepared. In the first solution, at least a catalyst 200, a polycationic compound 310, a polyanionic compound 320 and a polyionic complex-formation inhibitor are dissolved in the solvent. In the membrane formation process, the first solution is supplied onto a membrane and the polyionic complex-formation inhibitor in the first solution and the solvent are selectively permeated through the membrane to form the immobilized catalyst membrane on the membrane. In the immobilized catalyst membrane, the catalyst is immobilized in the polyionic complex comprising the polycationic compound and a polyanionic compound.
摘要翻译：待解决的问题：提供一种能够生产均匀的固定化酶膜的固定化催化剂膜的制备方法。解决方案：制备固定化催化剂膜100的方法具有制备方法和制备方法。在制备过程中，制备第一种溶液。在第一溶液中，至少将催化剂200，聚阳离子化合物310，聚阴离子化合物320和聚离子络合物形成抑制剂溶解在溶剂中。在膜形成过程中，将第一溶液供给到膜上，将第一溶液中的聚离子络合物形成抑制剂和溶剂选择性地渗透通过膜以在膜上形成固定的催化剂膜。在固定化催化剂膜中，将催化剂固定在包含聚阳离子化合物和聚阴离子化合物的聚离子络合物中。版权所有（C）2012，JPO＆INPIT

10. 发明专利

JP2012144610A Photoresponsive polymer and molded object made by forming the photoresponsive polymer, and its usage 有权
标题翻译：通过形成光电聚合物制备的聚合物和成型对象及其使用
公开(公告)号：JP2012144610A
公开(公告)日：2012-08-02
申请号：JP2011002989
申请日：2011-01-11
申请人： Kansai Univ , 学校法人関西大学
发明人： MIYATA TAKASHI , URAGAMI TADASHI , KOJIMA YURI
IPC分类号： C08F216/18 , C08F299/00 , C08G85/00 , G03H1/02 , G11B7/24 , G11B7/244
摘要： PROBLEM TO BE SOLVED: To provide a photoresponsiveness polymer capable of forming fine pattern in three dimensions, without requiring mold.SOLUTION: In the photoresponsive polymer which is a polymer including a photoresponsive group for forming a bridged structure by receiving irradiation with light, the photoresponsive group in a proportion corresponding to a light ray amount of the light forms the bridged structure, and thereby, a volume of the amount corresponding to the light ray amount of the light is decreased. The photoresponsive group is desired to be a dimerization group which is mutually dimerized by receiving irradiation with the light. A cinnamoyl group, a coumarin group, a thymine group, a quinone group, a maleimide group, a chalcone group, and a uracil group, etc. are exemplified as the dimerization group.
摘要翻译：要解决的问题：提供能够在不需要模具的情况下三维地形成精细图案的光响应性聚合物。解决方案：在通过接受光照射形成桥接结构的含有光响应基团的聚合物的光响应性聚合物中，与光的光线量相对应的光响应基团形成桥接结构，由此与光的光线量对应的量的体积减小。光响应群希望是通过接受光的照射而相互二聚的二聚化基团。作为二聚化基团，例示肉桂酰基，香豆素基，胸腺嘧啶基，醌基，马来酰亚胺基，查耳酮基和尿嘧啶基等。版权所有（C）2012，JPO＆INPIT

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