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    • 1. 发明申请
    • Medical bone prosthetic material and process for producing the same
    • 医用骨修复材料及其制造方法
    • US20060225619A1
    • 2006-10-12
    • US10562711
    • 2004-06-22
    • Kunio IshikawaShigeki MatsuyaMasaharu NakagawaKouichi Udou
    • Kunio IshikawaShigeki MatsuyaMasaharu NakagawaKouichi Udou
    • C04B12/02A61F2/28
    • A61L27/12A61L2430/02
    • There is disclosed a bone substitute material for medical use which satisfies all the requirements of (1) no histotoxicity, (2) osteoconductivity, (3) bone replacement capability, and (4) mechanical strength necessary for a bone reconstruction operation. The bone substitute material for medical use is predominantly composed of carbonate apatite and produced through the formation of carbonate apatite by contacting a block of calcium compound with a phosphate-containing solution, wherein the calcium compound block contains substantially no powders, and at least one of said calcium compound block and said phosphate solution contains a carbonate group, without any sintering. The block of calcium compound is preferably one prepared using an artificially synthesized calcium compound, most preferably a foamed calcium compound.
    • 公开了用于医​​疗用途的骨替代材料,其满足(1)无组织毒性,(2)骨传导性,(3)骨替代能力和(4)骨重建操作所需的机械强度的所有要求。 用于医疗用途的骨替代材料主要由碳酸盐磷灰石组成,并通过使钙化合物与含磷酸盐溶液接触而形成碳酸盐磷灰石,其中钙化合物块基本上不含粉末,并且至少一种 所述钙化合物嵌段和所述磷酸盐溶液含有碳酸酯基团,没有任何烧结。 钙化合物的嵌段优选使用人造合成的钙化合物,最优选发泡的钙化合物制备。
    • 2. 发明申请
    • BONE SUBSTITUTE MATERIAL FOR MEDICAL USE AND METHOD OF PRODUCING THE SAME
    • 用于医疗用途的骨替代材料及其生产方法
    • US20110295383A1
    • 2011-12-01
    • US13198760
    • 2011-08-05
    • Kunio ISHIKAWAShigeki MatsuyaMasaharu NakagawaKouichi Udou
    • Kunio ISHIKAWAShigeki MatsuyaMasaharu NakagawaKouichi Udou
    • A61F2/28
    • A61L27/12A61L2430/02
    • There is disclosed a bone substitute material for medical use which satisfies all the requirements of (1) no histotoxicity, (2) osteoconductivity, (3) bone replacement capability, and (4) mechanical strength necessary for a bone reconstruction operation. The bone substitute material for medical use is predominantly composed of carbonate apatite and produced through the formation of carbonate apatite by contacting a block of calcium compound with a phosphate-containing solution, wherein the calcium compound block contains substantially no powders, and at least one of said calcium compound block and said phosphate solution contains a carbonate group, without any sintering. The block of calcium compound is preferably one prepared using an artificially synthesized calcium compound, most preferably a foamed calcium compound.
    • 公开了用于医​​疗用途的骨替代材料,其满足(1)无组织毒性,(2)骨传导性,(3)骨替代能力和(4)骨重建操作所需的机械强度的所有要求。 用于医疗用途的骨替代材料主要由碳酸盐磷灰石组成,并通过使钙化合物与含磷酸盐溶液接触而形成碳酸盐磷灰石,其中钙化合物块基本上不含粉末,并且至少一种 所述钙化合物嵌段和所述磷酸盐溶液含有碳酸酯基团,没有任何烧结。 钙化合物的嵌段优选使用人造合成的钙化合物,最优选发泡的钙化合物制备。
    • 3. 发明授权
    • Medical bone prosthetic material and process for producing the same
    • 医用骨修复材料及其制造方法
    • US08012218B2
    • 2011-09-06
    • US10562711
    • 2004-06-22
    • Kunio IshikawaShigeki MatsuyaMasaharu NakagawaKouichi Udou
    • Kunio IshikawaShigeki MatsuyaMasaharu NakagawaKouichi Udou
    • A61F2/28
    • A61L27/12A61L2430/02
    • There is disclosed a bone substitute material for medical use which satisfies all the requirements of (1) no histotoxicity, (2) osteoconductivity, (3) bone replacement capability, and (4) mechanical strength necessary for a bone reconstruction operation. The bone substitute material for medical use is predominantly composed of carbonate apatite and produced through the formation of carbonate apatite by contacting a block of calcium compound with a phosphate-containing solution, wherein the calcium compound block contains substantially no powders, and at least one of said calcium compound block and said phosphate solution contains a carbonate group, without any sintering. The block of calcium compound is preferably one prepared using an artificially synthesized calcium compound, most preferably a foamed calcium compound.
    • 公开了用于医​​疗用途的骨替代材料,其满足(1)无组织毒性,(2)骨传导性,(3)骨替代能力和(4)骨重建操作所需的机械强度的所有要求。 用于医疗用途的骨替代材料主要由碳酸盐磷灰石组成,并通过使钙化合物与含磷酸盐溶液接触而形成碳酸盐磷灰石,其中钙化合物块基本上不含粉末,并且至少一种 所述钙化合物嵌段和所述磷酸盐溶液含有碳酸酯基团,没有任何烧结。 钙化合物的嵌段优选使用人造合成的钙化合物,最优选发泡的钙化合物制备。