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1. 发明授权

US07867973B2 Follistatin variant polypeptide 失效
标题翻译： Follistatin变体多肽
公开(公告)号：US07867973B2
公开(公告)日：2011-01-11
申请号：US11578408
申请日：2005-04-15
申请人： Kunihiro Tsuchida , Tatsuya Murakami
发明人： Kunihiro Tsuchida , Tatsuya Murakami
IPC分类号： C12P21/04 , A61K38/18 , C07K14/475
CPC分类号： C07K14/4703 , A61K38/00
摘要： The object of the present invention is to provide a follistatin variant capable of specifically inhibiting GDF-8 activity without inhibiting activin activity. The present invention provides a follistatin variant polypeptide, which (a) comprises follistatin domain I; (b) does not comprise an amino acid sequence that is represented by formula (I): Cys-(X1)a-Cys-(X2)b-Cys-(X3)c-Cys-(X4)d-Cys-(X5)e-Cys-(X6)f-Cys-(X7)g-Cys-(X8)h-Cys-(X9)i-Cys (SEQ ID NO: 30) wherein X1, X2, X3, X4, X5, X6, X7, X8, and X9 each independently represents the same or a different naturally occurring amino acid residue other than cysteine, “a” represents an integer between 2 and 6, “b” represents an integer between 3 and 7, “c” represents an integer between 7 and 11, “d” represents an integer between 0 and 4, “e” represents an integer between 1 and 6, “f” and “g” represent integers between 8 and 12, “h” represents an integer between 4 and 8, and “i” represents an integer between 11 and 15) and has 50% or more homology with the amino acid sequence of SEQ ID NO: 2 or SEQ ID NO: 29; and (c) selectively inhibits GDF-8 activity as compared with its inhibition of activin activity.
摘要翻译：本发明的目的是提供能够抑制GDF-8活性而不抑制激活素活性的卵泡抑素变异体。本发明提供了一种卵泡抑素变体多肽，其（a）包含卵泡抑素结构域I; （C） - （X 4）d-Cys-（X）的Cys-（X1）a-Cys-（X2）b-Cys- X5）e-Cys-（X6）f-Cys-（X7）g-Cys-（X8）h-Cys-（X9）i-Cys（SEQ ID NO：30）其中X1，X2，X3，X4，X5 ，X6，X7，X8和X9各自独立地表示除半胱氨酸以外的相同或不同的天然存在的氨基酸残基，“a”表示2至6之间的整数，“b”表示3至7之间的整数，“c “表示7到11之间的整数，”d“表示0和4之间的整数，”e“表示1和6之间的整数，”f“和”g“表示8和12之间的整数，”h“表示 4〜8之间的整数，“i”表示11〜15的整数），与SEQ ID NO：2或SEQ ID NO：29的氨基酸序列具有50％以上的同源性。和（c）与其抑制活化素活性相比，选择性地抑制GDF-8活性。

2. 发明申请

US20080090755A1 Follistatin Variant Polypeptide 失效
标题翻译： Follistatin变体多肽
公开(公告)号：US20080090755A1
公开(公告)日：2008-04-17
申请号：US11578408
申请日：2005-04-15
申请人： Kunihiro Tsuchida , Tatsuya Murakami
发明人： Kunihiro Tsuchida , Tatsuya Murakami
IPC分类号： A61K38/17 , A01K67/00 , A61K48/00 , A61P21/00 , A61P3/00 , A61P37/00 , C07H21/00 , C07K14/435 , C12N1/21 , C12N15/63 , C12P21/00 , C12Q1/66
CPC分类号： C07K14/4703 , A61K38/00
摘要： The object of the present invention is to provide a follistatin variant capable of specifically inhibiting GDF-8 activity without inhibiting activin activity. The present invention provides a follistatin variant polypeptide, which (a) comprises follistatin domain I; (b) does not comprise an amino acid sequence that is represented by formula (I): Cys-(X1)a-Cys-(X2)b-Cys-(X3)c-Cys-(X4)d-Cys-(X5)e-Cys-(X6)f-Cys-(X7)g-Cys-(X8)h-Cys-(X9)i-Cys (SEQ ID NO: 30) wherein X1, X2, X3, X4, X5, X6, X7, X8, and X9 each independently represents the same or a different naturally occurring amino acid residue other than cysteine, “a” represents an integer between 2 and 6, “b” represents an integer between 3 and 7, “c” represents an integer between 7 and 11, “d” represents an integer between 0 and 4, “e” represents an integer between 1 and 6, “f” and “g” represent integers between 8 and 12, “h” represents an integer between 4 and 8, and “i” represents an integer between 11 and 15) and has 50% or more homology with the amino acid sequence of SEQ ID NO: 2 or SEQ ID NO: 29; and (c) selectively inhibits GDF-8 activity as compared with its inhibition of activin activity.
摘要翻译：本发明的目的是提供能够抑制GDF-8活性而不抑制激活素活性的卵泡抑素变异体。本发明提供了一种卵泡抑素变体多肽，其（a）包含卵泡抑素结构域I; （B）不包含由式（I）表示的氨基酸序列：Cys-（X 1）S a - （X 2）（S-S）S-C（X S） C 6 - （X 5）5 - （X 6） -C≡-（X S>）Cys-（X S>）-Sys-（X < SEQ ID NO：30，其中X 1，X 2，X 2，...， X 4，X 4，X 5，X 6，X 7，X 6， 8和X 9各自独立地表示除半胱氨酸以外的相同或不同的天然存在的氨基酸残基，“a”表示2至6之间的整数，“b”表示整数在3和7之间，“c”表示7和11之间的整数，“d”表示0和4之间的整数，“e”表示1和6之间的整数，“f”和“g”表示8和 12中，“h”表示4〜8的整数，“i”表示11 a之间的整数 d 15），并且与SEQ ID NO：2或SEQ ID NO：29的氨基酸序列具有50％以上的同源性; 和（c）与其抑制活化素活性相比，选择性地抑制GDF-8活性。

3. 发明申请

US20140002620A1 VIDEO DISPLAY DEVICE 审中-公开
标题翻译：视频显示设备
公开(公告)号：US20140002620A1
公开(公告)日：2014-01-02
申请号：US13984975
申请日：2011-03-23
申请人： Tatsuya Murakami , Atsushi Irie , Shun Sakai
发明人： Tatsuya Murakami , Atsushi Irie , Shun Sakai
IPC分类号： H04N13/04
CPC分类号： H04N13/366 , G09G3/003 , G09G2320/06 , G09G2320/08 , G09G2354/00
摘要： A video display device has a display unit that displays one of a 3D video and a 2D video in a switching manner, a face detection unit that detects a face of a user from an image generated by an imaging unit, an image selection unit that estimates a utilization status of the user by analyzing features of the face detected by the face detection unit, and selects, based on a result of an estimation, whether to display the 3D or 2D video, and a display control unit that displays the video selected by the image selection unit to the display unit.
摘要翻译：视频显示设备具有以切换方式显示3D视频和2D视频之一的显示单元，从由成像单元生成的图像中检测用户面部的人脸检测单元，估计通过分析由人脸检测单元检测到的面部的特征，并且基于估计的结果来选择是否显示3D或2D视频，以及显示控制单元，其显示由所述图像选择单元到所述显示单元。

4. 发明申请

US20120280597A1 PIEZOELECTRIC RESONATOR DEVICE AND MANUFACTURING METHOD THEREFOR 有权
标题翻译：压电谐振器及其制造方法
公开(公告)号：US20120280597A1
公开(公告)日：2012-11-08
申请号：US13379709
申请日：2011-01-28
申请人： Koichi Kishimoto , Tadataka Koga , Tatsuya Murakami
发明人： Koichi Kishimoto , Tadataka Koga , Tatsuya Murakami
IPC分类号： H01L41/053 , H01L41/22
CPC分类号： H01L23/10 , H01L2924/0002 , H01L2924/16315 , H03H9/1021 , H03H9/1035 , H01L2924/00
摘要： A piezoelectric resonator device in which excitation electrodes of a piezoelectric resonator plate are hermetically sealed, includes a plurality of sealing members that hermetically seal the excitation electrodes of the piezoelectric resonator plate. The plurality of sealing members each have a bonding layer, and at least one of the plurality of sealing members is provided with a bank portion and having the bonding layer formed on a top face of the bank portion. The plurality of sealing members are bonded together with the bonding layers of the sealing members, and a bonding material that contains an intermetallic compound is formed.
摘要翻译：压电谐振器的激励电极密封的压电谐振器装置包括密封压电谐振器板的激励电极的多个密封构件。多个密封构件各自具有接合层，并且多个密封构件中的至少一个密封构件设置有堤部，并且在堤部的顶面上形成有接合层。多个密封构件与密封构件的接合层结合在一起，并且形成包含金属间化合物的接合材料。

5. 发明授权

US08209495B2 Storage management method and storage management system 有权
标题翻译：存储管理方法和存储管理系统
公开(公告)号：US08209495B2
公开(公告)日：2012-06-26
申请号：US13073370
申请日：2011-03-28
申请人： Shuichi Yagi , Kozue Fujii , Tatsuya Murakami
发明人： Shuichi Yagi , Kozue Fujii , Tatsuya Murakami
IPC分类号： G06F12/10
CPC分类号： G06F9/5077 , G06F3/0605 , G06F3/0631 , G06F3/0637 , G06F3/067 , G06F9/5016
摘要： There is provided a storage management system capable of utilizing division management with enhanced flexibility and of enhancing security of the entire system, by providing functions by program products in each division unit of a storage subsystem. The storage management system has a program-product management table stored in a shared memory in the storage subsystem and showing presence or absence of the program products, which provide management functions of respective resources to respective SLPRs. At the time of executing the management functions by the program products in the SLPRs of users in accordance with instructions from the users, the storage management system is referred to and execution of the management function having no program product is restricted.
摘要翻译：提供了一种存储管理系统，其能够通过在存储子系统的每个分割单元中通过程序产品提供功能来利用增强的灵活性和增强整个系统的安全性的划分管理。存储管理系统具有存储在存储子系统中的共享存储器中的程序产品管理表，并且显示存在或不存在对相应SLPR提供相应资源的管理功能的程序产品。在根据用户的指示由用户的SLPR中的程序产品执行管理功能时，参考存储管理系统并且限制没有程序产品的管理功能的执行。

6. 发明授权

US08004157B2 Piezoelectric resonator plate and piezoelectric resonator device 有权
标题翻译：压电谐振板和压电谐振器装置
公开(公告)号：US08004157B2
公开(公告)日：2011-08-23
申请号：US11885260
申请日：2006-03-02
申请人： Minoru Iizuka , Tatsuya Murakami , Syunsuke Satoh , Takashi Shirai , Hiroyuki Ishihara , Tomo Fujii
发明人： Minoru Iizuka , Tatsuya Murakami , Syunsuke Satoh , Takashi Shirai , Hiroyuki Ishihara , Tomo Fujii
IPC分类号： H01L41/08
CPC分类号： H03H9/1021 , H03H9/215
摘要： An electrode forming region for providing lead electrodes (65a, 65b) is provided on a crystal resonator plate (2). Opposed side surfaces (67a, 67b) of a substrate (6) are formed and inclined in the same direction with respect to a front major surface (63). Also, an adhesion reinforcing portion (7) for reinforcing adhesion to a conductive adhesive (5) is provided in the electrode forming region for the lead electrodes (65a, 65b). For example, the adhesion reinforcing portion (7) is a notch portion which is cut and formed in the opposed side surfaces (67a, 67b). Thereby, an adhesion strength of the crystal resonator plate (2) and the conductive adhesive (5) is increased.
摘要翻译：在晶体谐振器板（2）上设置用于提供引线电极（65a，65b）的电极形成区域。形成基板（6）的相对的侧面（67a，67b）并相对于前主表面（63）沿相同的方向倾斜。此外，在用于引线电极（65a，65b）的电极形成区域中设置有用于增强与导电粘合剂（5）的粘附的粘合增强部分（7）。例如，粘合强化部（7）是在相对的侧面（67a，67b）上切断并形成的切口部。由此，增加了晶体谐振器板（2）和导电粘合剂（5）的粘附强度。

7. 发明授权

US07869104B2 Medium feeding apparatus and image forming apparatus 有权
标题翻译：中等供料装置和成像装置
公开(公告)号：US07869104B2
公开(公告)日：2011-01-11
申请号：US11684171
申请日：2007-03-09
申请人： Tatsuya Murakami
发明人： Tatsuya Murakami
IPC分类号： H04N1/04
CPC分类号： B65H1/04 , B41J13/103 , B65H2405/111643 , B65H2405/111646 , B65H2405/324
摘要： A medium feeding apparatus includes a main body, and a medium placing unit at least a part of which can be housed in the main body. The medium placing unit includes a first placing unit held by the main body in such a manner that the first placing unit is shiftable between a housed position where at least one of the first placing unit is housed in the main body and a placing position where the medium can be placed on the first placing unit, a second placing unit has a first shifting condition where the medium can be placed on the first and second placing units and a second shifting condition where the second placing unit is overlapped with the first placing unit, and an auxiliary member disposed on a boundary between the first placing unit and the second placing unit when the second placing unit is in the first shifting condition.
摘要翻译：介质供给装置包括主体和介质放置单元，其至少一部分可以容纳在主体中。介质放置单元包括第一放置单元，该第一放置单元以第一放置单元可在第一放置单元中的至少一个容纳在主体中的容纳位置与放置位置之间移动，介质可以放置在第一放置单元上，第二放置单元具有第一移动状态，其中介质可以放置在第一和第二放置单元上，以及第二移位条件，其中第二放置单元与第一放置单元重叠，以及当所述第二放置单元处于所述第一移动状态时，设置在所述第一放置单元和所述第二放置单元之间的边界上的辅助构件。

8. 发明授权

US07668501B2 Medium supplying apparatus and image forming apparatus 有权
标题翻译：中等供给装置和图像形成装置
公开(公告)号：US07668501B2
公开(公告)日：2010-02-23
申请号：US11965183
申请日：2007-12-27
申请人： Tatsuya Murakami , Takahiro Sunohara
发明人： Tatsuya Murakami , Takahiro Sunohara
IPC分类号： G03G15/00 , G03G21/00 , B65H3/44 , B65H1/00
CPC分类号： B41J13/103 , B41J29/023 , B65H1/04 , B65H2402/31 , G03G15/6502
摘要： A medium supplying apparatus is assembled to an image forming apparatus. A medium tray supports a medium thereon, and is pivotal about a first axis and extends from the first axis. The medium tray has a guide path that extends in the first radial direction. A feeder frame has a pickup roller rotatably mounted to the feeder frame, and is pivotal about a second axis substantially parallel to the first axis. The medium tray and the feeder frame are drivingly coupled via a link. When the medium tray pivots to its open position or closed position, the link transmits the motion of the medium tray to the feeder frame in such a way that the feeder frame drivingly pivots to its open position or closed position.
摘要翻译：向图像形成装置组装介质供给装置。介质托盘支撑其上的介质，并且绕第一轴线枢转并且从第一轴线延伸。介质托盘具有沿第一径向方向延伸的引导路径。馈送框架具有可旋转地安装到馈送框架的拾取辊，并且绕基本上平行于第一轴线的第二轴线枢转。介质托盘和进料器框架通过连杆驱动耦合。当介质托盘枢转到其打开位置或关闭位置时，连杆将介质托盘的运动传递到进料器框架，使得进料架驱动地枢转到其打开位置或关闭位置。

9. 发明授权

US07547765B2 Branched polyalkylene glycols 有权
标题翻译：支链聚亚烷基二醇
公开(公告)号：US07547765B2
公开(公告)日：2009-06-16
申请号：US11877011
申请日：2007-10-23
申请人： Motoo Yamasaki , Toshiyuki Suzawa , Tatsuya Murakami , Noriko Sukurai , Kinya Yamashita , Mayumi Mukai , Takashi Kuwabara
发明人： Motoo Yamasaki , Toshiyuki Suzawa , Tatsuya Murakami , Noriko Sukurai , Kinya Yamashita , Mayumi Mukai , Takashi Kuwabara
IPC分类号： C07K17/06 , A61K31/765 , A61K47/48 , C07D207/408 , C07D309/10
CPC分类号： C08G65/3311 , A61K38/00 , A61K47/60 , A61K47/62 , A61K47/641 , A61K47/642 , C08G65/329 , C08L2203/02
摘要： The present invention provides a branched polyalkylene glycol wherein three or more single-chain polyalkylene glycols and a group having reactivity with an amino acid side chain, the N-terminal amino group or the C-terminal carboxyl group in a polypeptide or a group convertible into the group having reactivity are bound; and a physiologically active polypeptide modified with the branched polyalkylene glycol.
摘要翻译：本发明提供一种支链聚亚烷基二醇，其中三个或更多个单链聚亚烷基二醇和与多肽或可转化为多肽的基团中的氨基酸侧链，N-末端氨基或C-末端羧基具有反应性的基团具有反应性的基团被结合; 和用支链聚亚烷基二醇改性的生理活性多肽。

10. 发明申请

US20080265717A1 Piezoelectric Resonator Plate and Piezoelectric Resonator Device 有权
标题翻译：压电谐振器板和压电谐振器器件
公开(公告)号：US20080265717A1
公开(公告)日：2008-10-30
申请号：US11885260
申请日：2006-03-02
申请人： Minoru Iizuka , Tatsuya Murakami , Syunsuke Satoh , Takashi Shirai , Hiroyuki Ishihara , Tomo Fujii
发明人： Minoru Iizuka , Tatsuya Murakami , Syunsuke Satoh , Takashi Shirai , Hiroyuki Ishihara , Tomo Fujii
IPC分类号： H03H9/10
CPC分类号： H03H9/1021 , H03H9/215
摘要： An electrode forming region for providing lead electrodes (65a, 65b) is provided on a crystal resonator plate (2). Opposed side surfaces (67a, 67b) of a substrate (6) are formed and inclined in the same direction with respect to a front major surface (63). Also, an adhesion reinforcing portion (7) for reinforcing adhesion to a conductive adhesive (5) is provided in the electrode forming region for the lead electrodes (65a, 65b). For example, the adhesion reinforcing portion (7) is a notch portion which is cut and formed in the opposed side surfaces (67a, 67b). Thereby, an adhesion strength of the crystal resonator plate (2) and the conductive adhesive (5) is increased.
摘要翻译：在晶体谐振器板（2）上设置用于提供引线电极（65a，65b）的电极形成区域。形成基板（6）的相对的侧面（67a，67b）并相对于前主表面（63）沿相同的方向倾斜。此外，在用于引线电极（65a，65b）的电极形成区域中设置用于增强与导电粘合剂（5）的粘附的粘附强化部分（7）。例如，粘合强化部（7）是在相对的侧面（67a，67b）中被切割并形成的切口部。由此，增加了晶体谐振器板（2）和导电粘合剂（5）的粘附强度。

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