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1. 发明授权

US07320703B2 Method for inserting a prosthesis 失效
标题翻译：插入假体的方法
公开(公告)号：US07320703B2
公开(公告)日：2008-01-22
申请号：US11077890
申请日：2005-03-11
申请人： Kristian DiMatteo , Robert Thistle , John Spiridigliozzi
发明人： Kristian DiMatteo , Robert Thistle , John Spiridigliozzi
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/88 , A61F2/89 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/075 , A61F2002/9511 , A61F2002/9583 , Y10S623/903
摘要： A graft system for intraluminal delivery in a vessel in need of repair comprising a graft, anchoring means, and a strippable sheath around at least part of the graft. A preferred anchoring means is a balloon-expandable stent. Also included in the invention is a method of using the device to treat a body lumen. The strippable sheath is removable by pulling on a drawstring to remove it which permits expansion of the graft. The positioning of the device may then be adjusted prior to stent dilation. A preferred embodiment of the invention includes a bifurcated graft system for intraluminal delivery in an aortic aneurysm comprising a bifurcated graft having a distal region and two legs, an expandable stent disposed in part of the distal region, and a strippable crocheted sheath around the distal region and one of the two legs. The strippable crocheted sheath is removable by untying it to permit expansion of the graft after initial placement within the aneurysm.
摘要翻译：用于需要修复的血管内腔内输送的移植物系统，包括移植物的至少部分周围的移植物，锚定装置和可剥离护套。优选的锚定装置是球囊可扩张的支架。本发明还包括使用该装置来治疗体腔的方法。可剥离的护套可以通过拉动束带来移除，以移除它，这允许移植物膨胀。然后可以在支架扩张之前调整装置的定位。本发明的优选实施方案包括用于主动脉瘤内腔内递送的分叉移植物系统，其包括具有远侧区域和两条腿的分叉移植物，位于远端区域的一部分中的可扩张支架和围绕远端区域的可剥离钩编护套和两条腿之一。可剥离的钩编护套可以通过拆卸它来移除，以允许在初始放置在动脉瘤内之后扩张移植物。

2. 发明申请

US20050228476A1 Method for inserting a prosthesis 失效
标题翻译：插入假体的方法
公开(公告)号：US20050228476A1
公开(公告)日：2005-10-13
申请号：US11077890
申请日：2005-03-11
申请人： Kristian DiMatteo , Robert Thistle , John Spiridigliozzi
发明人： Kristian DiMatteo , Robert Thistle , John Spiridigliozzi
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/88 , A61F2/89 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/075 , A61F2002/9511 , A61F2002/9583 , Y10S623/903
摘要： A graft system for intraluminal delivery in a vessel in need of repair comprising a graft, anchoring means, and a strippable sheath around at least part of the graft. A preferred anchoring means is a balloon-expandable stent. Also included in the invention is a method of using the device to treat a body lumen. The strippable sheath is removable by pulling on a drawstring to remove it which permits expansion of the graft. The positioning of the device may then be adjusted prior to stent dilation. A preferred embodiment of the invention includes a bifurcated graft system for intraluminal delivery in an aortic aneurysm comprising a bifurcated graft having a distal region and two legs, an expandable stent disposed in part of the distal region, and a strippable crocheted sheath around the distal region and one of the two legs. The strippable crocheted sheath is removable by untying it to permit expansion of the graft after initial placement within the aneurysm.
摘要翻译：用于需要修复的血管内腔内输送的移植物系统，包括移植物的至少部分周围的移植物，锚定装置和可剥离护套。优选的锚定装置是球囊可扩张的支架。本发明还包括使用该装置来治疗体腔的方法。可剥离的护套可以通过拉动束带来移除，以移除它，这允许移植物膨胀。然后可以在支架扩张之前调整装置的定位。本发明的优选实施方案包括用于主动脉瘤内腔内递送的分叉移植物系统，其包括具有远侧区域和两条腿的分叉移植物，位于远端区域的一部分中的可扩张支架和围绕远端区域的可剥离钩编护套和两条腿之一。可剥离的钩编护套可以通过拆卸它来移除，以允许在初始放置在动脉瘤内之后扩张移植物。

3. 发明授权

US07763062B2 Method and system for delivering and implanting a graft 失效
标题翻译：用于输送和植入移植物的方法和系统
公开(公告)号：US07763062B2
公开(公告)日：2010-07-27
申请号：US10348575
申请日：2003-01-21
申请人： John Spiridigliozzi , Kristian DiMatteo , Robert C. Thistle
发明人： John Spiridigliozzi , Kristian DiMatteo , Robert C. Thistle
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61B17/12022 , A61B17/12118 , A61B17/12131 , A61B2017/1205 , A61F2/07 , A61F2/95 , A61F2002/9511
摘要： A method and apparatus of treating an abdominal aortic aneurysm in a patient includes the steps of providing a deployable tubular graft of length to extend across the aneurysm. The graft is inserted endovascularly through an artery communicating with the aorta to a site within the aorta whereby an insertion end of the graft is positioned adjacent a non-dilated region of the aorta. The graft is deployed such that the insertion end of the graft is placed against an interior wall of the non-dilated region of the aorta. The graft is held from within the graft against the interior walls of the aorta and while being held, sutures are introduced laparoscopically through a wall of the aorta to the exterior of the graft whereby the graft is sutured to the inner walls of the aorta and the graft.
摘要翻译：一种治疗患者腹主动脉瘤的方法和装置包括以下步骤：提供长度可延伸穿过动脉瘤的可展开的管状移植物。移植物通过与主动脉连通的动脉血管内插入到主动脉内的部位，由此移植物的插入端邻近主动脉的非扩张区域定位。将移植物部署成使得移植物的插入端抵靠主动脉的非扩张区域的内壁放置。移植物从移植物内部抵靠主动脉的内壁保持，并且在被保持的同时，将缝合线通过腹腔镜穿过主动脉的壁到移植物的外部，由此将移植物缝合到主动脉的内壁，并且接枝。

4. 发明申请

US20110245906A1 Sealable Attachment of Endovascular Stent To Graft 有权
标题翻译：血管内支架对移植物的可密封附件
公开(公告)号：US20110245906A1
公开(公告)日：2011-10-06
申请号：US13160105
申请日：2011-06-14
申请人： Kristian DiMatteo , John Spiridigliozzi , Robert C. Thistle
发明人： Kristian DiMatteo , John Spiridigliozzi , Robert C. Thistle
IPC分类号： A61F2/82
CPC分类号： A61F2/07 , A61F2/90 , A61F2002/065 , A61F2002/075 , A61F2220/005 , A61F2220/0058 , A61F2220/0075
摘要： An endovascular prosthesis of the present invention includes an expandable stent and a means for sealably attaching a tubular graft to the stent within the stent's lumen. The means of sealably attaching a graft includes membranes, foams, polymeric materials and combinations thereof. Additionally, the present invention includes methods of forming an endovascular prosthesis and methods of implanting an endovascular prosthesis within a vessel to provide sealable securement of a tubular graft within the stent's lumen.
摘要翻译：本发明的血管内假体包括可扩张支架和用于将管状移植物密封地附接到支架内的支架内的装置。可密封地连接移植物的方法包括膜，泡沫，聚合材料及其组合。另外，本发明包括形成血管内假体的方法和在血管内植入血管内假体以提供管状移植物在支架内腔内的可密封固定的方法。

5. 发明授权

US08845714B2 Sealable attachment of endovascular stent to graft 有权
标题翻译：血管内支架的可密封附件移植
公开(公告)号：US08845714B2
公开(公告)日：2014-09-30
申请号：US13160105
申请日：2011-06-14
申请人： Kristian DiMatteo , John Spiridigliozzi , Robert C. Thistle
发明人： Kristian DiMatteo , John Spiridigliozzi , Robert C. Thistle
IPC分类号： A61F2/06 , A61F2/07 , A61F2/90
CPC分类号： A61F2/07 , A61F2/90 , A61F2002/065 , A61F2002/075 , A61F2220/005 , A61F2220/0058 , A61F2220/0075
摘要： An endovascular prosthesis of the present invention includes an expandable stent and a means for sealably attaching a tubular graft to the stent within the stent's lumen. The means of sealably attaching a graft includes membranes, foams, polymeric materials and combinations thereof. Additionally, the present invention includes methods of forming an endovascular prosthesis and methods of implanting an endovascular prosthesis within a vessel to provide sealable securement of a tubular graft within the stent's lumen.
摘要翻译：本发明的血管内假体包括可扩张支架和用于将管状移植物密封地附接到支架内的支架内的装置。可密封地连接移植物的方法包括膜，泡沫，聚合材料及其组合。另外，本发明包括形成血管内假体的方法和在血管内植入血管内假体以提供管状移植物在支架内腔内的可密封固定的方法。

6. 发明授权

US08649543B2 Systems and methods to provide communication and monitoring of user status 有权
标题翻译：提供通信和监控用户状态的系统和方法
公开(公告)号：US08649543B2
公开(公告)日：2014-02-11
申请号：US13208588
申请日：2011-08-12
申请人： Amir A. Abolfathi , John Spiridigliozzi
发明人： Amir A. Abolfathi , John Spiridigliozzi
IPC分类号： H04R25/00
CPC分类号： A61B5/682 , A61B5/0006 , A61B5/0022 , A61B5/0028 , A61B5/02438 , A61B5/0402 , A61B5/0816 , A61B5/11 , A61B5/1112 , A61B5/1117 , A61B5/4547 , A61B5/72 , A61B5/7455 , A61B7/04 , A61B2503/20 , A61B2562/0219 , A61C7/08 , A63B71/085 , B33Y70/00 , B33Y80/00
摘要： An electronic and transducer device can be attached, adhered, or otherwise embedded into or upon a removable oral appliance or other oral device to form a two-way communication assembly. The device contains a motion sensor to detect external forces imposed on the user such as an explosion, for example. The information is stored for medical treatment, among others. In another embodiment, the device provides an electronic and transducer device that can be attached, adhered, or otherwise embedded into or upon a removable oral appliance or other oral device to form a medical tag containing patient identifiable information. Such an oral appliance may be a custom-made device fabricated from a thermal forming process utilizing a replicate model of a dental structure obtained by conventional dental impression methods. The electronic and transducer assembly may receive incoming sounds either directly or through a receiver to process and amplify the signals and transmit the processed sounds via a vibrating transducer element coupled to a tooth or other bone structure, such as the maxillary, mandibular, or palatine bone structure.
摘要翻译：电子和换能器装置可以被附接，粘附或以其它方式嵌入到可拆卸的口器具或其它口腔装置中或之上，以形成双向通信组件。该装置包含运动传感器，用于检测施加在用户上的外力，例如爆炸。信息存储在医疗中等等。在另一个实施例中，该装置提供电子和换能器装置，其可以附接，粘附或以其它方式嵌入到可移除的口腔器具或其它口腔装置中或之上，以形成包含患者可识别信息的医疗标签。这样的口器具可以是使用通过常规牙印模法获得的牙科结构的重复模型的热成型方法制造的定制装置。电子和换能器组件可以直接或通过接收器接收输入声音，以处理和放大信号，并经由耦合到牙齿或其它骨结构（例如上颌骨，下颌骨或腭骨）的振动换能器元件传送经处理的声音结构体。

7. 发明授权

US08333203B2 Custom fitted intra-oral appliances 有权
标题翻译：定制配套口腔器具
公开(公告)号：US08333203B2
公开(公告)日：2012-12-18
申请号：US12169145
申请日：2008-07-08
申请人： John Spiridigliozzi , Amir Abolfathi , Emir Deljkich
发明人： John Spiridigliozzi , Amir Abolfathi , Emir Deljkich
IPC分类号： A61C5/14
CPC分类号： H04R25/606 , A61C13/0019 , A61F11/00 , A61F11/04 , B33Y80/00 , H04R17/00 , H04R25/40 , H04R25/604 , H04R25/75 , H04R2225/67 , H04R2460/13
摘要： Methods and apparatus for transmitting vibrations via an electronic and/or actuator assembly through a custom-fitted dental appliance are disclosed herein. The customized fitting is done by the user. The assembly may be attached, adhered, or otherwise embedded intra-orally on a tooth or oral tissue. The electronic and actuator assembly may receive incoming sounds either directly or through a receiver to process and amplify the signals and transmit the processed sounds via a vibrating actuator element coupled to a tooth or other bone structure, such as the maxillary, mandibular, or palatine bone structure.
摘要翻译：本文公开了通过定制安装的牙科器具通过电子和/或致动器组件传递振动的方法和装置。定制的配件由用户完成。组合体可以附着，粘附或以其他方式嵌入到牙齿或口腔组织上。电子和致动器组件可以直接或通过接收器接收进入的声音，以处理和放大信号并且经由耦合到牙齿或其他骨结构（例如上颌骨，下颌骨或腭骨）的振动致动器元件传送经处理的声音结构体。

8. 发明授权

US08047407B2 Apparatus and method for delivery of biologic sealant 有权
标题翻译：用于输送生物密封剂的装置和方法
公开(公告)号：US08047407B2
公开(公告)日：2011-11-01
申请号：US11977441
申请日：2007-10-24
申请人： John L. Wheeler , Gary Whipple , A. David Boccuti , Thomas T. Washburn , Andrew Nicholas Gentile , J. Brent Ratz , John Spiridigliozzi
发明人： John L. Wheeler , Gary Whipple , A. David Boccuti , Thomas T. Washburn , Andrew Nicholas Gentile , J. Brent Ratz , John Spiridigliozzi
IPC分类号： B65D88/54
CPC分类号： A61B17/00491 , A61B17/0057 , A61B2017/00495 , A61K38/363 , A61K38/482 , A61K45/06 , A61L24/106 , A61L27/225 , A61L27/50 , A61L27/54 , A61L2300/00 , A61L2400/06 , A61L2430/38 , B05C17/00553 , B05C17/0116 , Y10T29/49826 , A61K2300/00
摘要： A device for delivery of biologic materials, comprising: a cartridge having at least two cylinder bores for fluids to be delivered, wherein each cylinder includes an exit port for a fluid, a plunger within each cylinder for pushing the fluids out of the cylinder, a housing adapted to receive the cartridge, wherein the housing or cartridge includes an adaptor to receive and lock a manifold that operably connects to the exit ports of the cartridge, at least two toothed rams, wherein each toothed ram is at least partially within a cylinder bore, a trigger connected to the housing, wherein the trigger includes a toothed drive rack, a toothed wheel assembly that cooperates with the toothed drive rack and with the toothed rams, as well as methods of making the device, methods of using the device to treat discs, kits including the device.
摘要翻译：一种用于输送生物材料的装置，包括：具有用于待输送流体的至少两个气缸孔的筒，其中每个气缸包括用于流体的出口，用于将流体推出气缸的每个气缸内的柱塞，壳体，其适于接收所述盒，其中所述壳体或盒包括用于接收和锁定歧管的适配器，所述歧管可操作地连接到所述药筒的出口，至少两个齿状的公柱，其中每个齿状的压头至少部分地在汽缸孔内触发器，其连接到所述壳体，其中所述触发器包括齿形驱动齿条，与所述齿形驱动齿条和所述齿状凸起协作的齿轮组件，以及制造所述装置的方法，使用所述装置的方法来治疗光盘，套件，包括设备。

9. 发明申请

US20100049291A1 STENT WITH IMPROVED RESISTANCE TO MIGRATION 审中-公开
标题翻译：具有改善抵抗力的电梯
公开(公告)号：US20100049291A1
公开(公告)日：2010-02-25
申请号：US12606874
申请日：2009-10-27
申请人： Ilya Yampolsky , John Spiridigliozzi
发明人： Ilya Yampolsky , John Spiridigliozzi
IPC分类号： A61F2/82
CPC分类号： A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/067 , A61F2220/0033 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2250/0042
摘要： A modular mating stent is adapted to resist migration within a receiving stent. The modular mating stent has a substantially self-expandable first section of predetermined compressibility that is adapted to permit the first section to conform to the shape of a body lumen surrounding the first section. The modular mating stent also has a balloon-expandable second section that is less compressible than the first section, which is adapted to firmly engage a surface of the receiving stent surrounding the second section.
摘要翻译：模块化配合支架适于抵抗接收支架内的迁移。模块化配合支架具有预定的可压缩性的基本上可自膨胀的第一部分，其适于允许第一部分符合围绕第一部分的体腔的形状。模块化配合支架还具有比第一部分更不可压缩的球囊可扩张的第二部分，其适于牢固地接合围绕第二部分的接收支架的表面。

10. 发明授权

US07588596B2 Endoluminal prosthesis adapted to resist migration and method of deploying the same 失效
标题翻译：适于抵抗迁移的腔内假体及其部署方法
公开(公告)号：US07588596B2
公开(公告)日：2009-09-15
申请号：US11025020
申请日：2004-12-29
申请人： John Spiridigliozzi , Ilya Yampolski
发明人： John Spiridigliozzi , Ilya Yampolski
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61F2/07 , A61F2/88 , A61F2/89 , A61F2/90 , A61F2/954 , A61F2002/061 , A61F2002/065 , A61F2002/072 , A61F2002/075 , A61F2002/828 , A61F2230/0054 , A61F2250/0003
摘要： An endoluminal prosthesis for treatment of a condition in a lumen in the vicinity of a branch lumen, the lumen being adapted to resist migration, is provided. In one embodiment, the prosthesis includes a substantially tubular main stent adapted for placement in the main lumen. A substantially tubular anchor stent is connected to the main stent and adapted for placement in the branch lumen.
摘要翻译：提供了一种用于治疗分支内腔附近的内腔中的状况的腔内假体，该内腔适于抵抗迁移。在一个实施例中，假体包括适于放置在主腔内的基本上管状的主支架。基本上管状的锚固支架连接到主支架并适于放置在分支内腔中。

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