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1. 发明授权

US08198464B2 Method for producing C-glycoside derivative and intermediate for synthesis thereof 失效
标题翻译：制备C-糖苷衍生物的方法及其合成中间体
公开(公告)号：US08198464B2
公开(公告)日：2012-06-12
申请号：US12520484
申请日：2007-12-20
申请人： Kousuke Komenoi , Atsushi Nakamura , Makoto Kasai , Masakazu Imamura , Ryota Shiraki , Keita Nakanishi
发明人： Kousuke Komenoi , Atsushi Nakamura , Makoto Kasai , Masakazu Imamura , Ryota Shiraki , Keita Nakanishi
IPC分类号： C07D409/08
CPC分类号： C07D409/10 , C07D333/54
摘要： The present invention provides a method for producing a C-glycoside derivative, which can produce the C-glycoside derivative at a high yield and at a low cost, which conforms to environmental protection, and which is applicable industrially. The C-glycoside derivative is useful for treating and preventing diabetes such as insulin-dependent diabetes (type 1 diabetes), non-insulin-dependent diabetes (type 2 diabetes) and the like and various diabetes-related diseases including insulin-resistant diseases and obesity.
摘要翻译：本发明提供一种生产C-糖苷衍生物的方法，该方法可以以高产率和低成本生产符合环境保护并且在工业上可应用的C-糖苷衍生物。 C-糖苷衍生物可用于治疗和预防诸如胰岛素依赖性糖尿病（1型糖尿病），非胰岛素依赖性糖尿病（2型糖尿病）等糖尿病和各种糖尿病相关疾病，包括胰岛素抵抗性疾病和肥胖。

2. 发明申请

US20100094025A1 METHOD FOR PRODUCING C-GLYCOSIDE DERIVATIVE AND INTERMEDIATE FOR SYNTHESIS THEREOF 失效
标题翻译：生产C-谷氨酰胺衍生物的方法及其合成方法
公开(公告)号：US20100094025A1
公开(公告)日：2010-04-15
申请号：US12520484
申请日：2007-12-20
申请人： Kousuke Komenoi , Atsushi Nakamura , Makoto Kasai , Masakazu Imamura , Ryota Shiraki , Keita Nakanishi
发明人： Kousuke Komenoi , Atsushi Nakamura , Makoto Kasai , Masakazu Imamura , Ryota Shiraki , Keita Nakanishi
IPC分类号： C07D333/56
CPC分类号： C07D409/10 , C07D333/54
摘要： The present invention provides a method for producing a C-glycoside derivative, which can produce the C-glycoside derivative at a high yield and at a low cost, which conforms to environmental protection, and which is applicable industrially. The C-glycoside derivative is useful for treating and preventing diabetes such as insulin-dependent diabetes (type 1 diabetes), non-insulin-dependent diabetes (type 2 diabetes) and the like and various diabetes-related diseases including insulin-resistant diseases and obesity.
摘要翻译：本发明提供一种生产C-糖苷衍生物的方法，该方法可以以高产率和低成本生产符合环境保护并且在工业上可应用的C-糖苷衍生物。 C-糖苷衍生物可用于治疗和预防诸如胰岛素依赖性糖尿病（1型糖尿病），非胰岛素依赖性糖尿病（2型糖尿病）等糖尿病和各种糖尿病相关疾病，包括胰岛素抵抗性疾病和肥胖。

3. 发明授权

US08097592B2 Cocrystal of C-glycoside derivative and L-proline 有权
标题翻译： C-糖苷衍生物和L-脯氨酸的晶体
公开(公告)号：US08097592B2
公开(公告)日：2012-01-17
申请号：US12296056
申请日：2007-04-04
申请人： Masakazu Imamura , Keita Nakanishi , Ryota Shiraki , Kenichi Onda , Daisuke Sasuga , Masamichi Yuda
发明人： Masakazu Imamura , Keita Nakanishi , Ryota Shiraki , Kenichi Onda , Daisuke Sasuga , Masamichi Yuda
IPC分类号： A61K31/70 , C07H1/00
CPC分类号： C07D207/16 , C07D409/10
摘要： A cocrystal of (1S)-1,5-anhydro-1-[3-(1-benzothien-2-ylmethyl)-4-fluorophenyl]-D-glucitol and L-proline. It is a cocrystal of known compound A, which has a constant quality, is superior in storage stability, has no moisture absorptivity, and is suitable as a crystal of a drug substance used for preparing pharmaceuticals.
摘要翻译：（1S）-1,5-脱水-1- [3-（1-苯并噻吩-2-基甲基）-4-氟苯基] -D-葡萄糖醇和L-脯氨酸的共结晶体。已知的化合物A的共晶体具有恒定的质量，储存稳定性优异，不具有吸湿性，并且适合作为用于制备药物的药物的晶体。

4. 发明申请

US20090143316A1 COCRYSTAL OF C-GLYCOSIDE DERIVATIVE AND L-PROLINE 有权
标题翻译： C-GLYCOSIDE衍生物和L-丙氨酸的晶体
公开(公告)号：US20090143316A1
公开(公告)日：2009-06-04
申请号：US12296056
申请日：2007-04-04
申请人： Masakazu Imamura , Keita Nakanishi , Ryota Shiraki , Kenichi Onda , Daisuke Sasuga , Masamichi Yuda
发明人： Masakazu Imamura , Keita Nakanishi , Ryota Shiraki , Kenichi Onda , Daisuke Sasuga , Masamichi Yuda
IPC分类号： A61K31/7004 , C07H17/02 , A61P3/10
CPC分类号： C07D207/16 , C07D409/10
摘要： A cocrystal of (1S)-1,5-anhydro-1-[3-(1-benzothien-2-ylmethyl)-4-fluorophenyl]-D-glucitol and L-proline. It is a cocrystal of known compound A, which has a constant quality, is superior in storage stability, has no moisture absorptivity, and is suitable as a crystal of a drug substance used for preparing pharmaceuticals.
摘要翻译：（1S）-1,5-脱水-1- [3-（1-苯并噻吩-2-基甲基）-4-氟苯基] -D-葡萄糖醇和L-脯氨酸的共结晶体。已知的化合物A的共晶体具有恒定的质量，储存稳定性优异，不具有吸湿性，并且适合作为用于制备药物的药物的晶体。

5. 发明申请

US20090182039A1 Choline Salt Crystal of Azulene Compound 审中-公开
标题翻译：胆红素化合物的胆碱盐晶体
公开(公告)号：US20090182039A1
公开(公告)日：2009-07-16
申请号：US11988383
申请日：2006-07-06
申请人： Masakazu Imamura , Takayuki Suzuki , Takeshi Murakami , Keita Nakanishi , Hiroshi Uebayashi , Haruka Nakamura , Masamichi Yuda , Naoko Amenomiya , Yuuji Awamura , Hiroshi Tomiyama
发明人： Masakazu Imamura , Takayuki Suzuki , Takeshi Murakami , Keita Nakanishi , Hiroshi Uebayashi , Haruka Nakamura , Masamichi Yuda , Naoko Amenomiya , Yuuji Awamura , Hiroshi Tomiyama
IPC分类号： A61K31/351 , C07D315/00
CPC分类号： C07C215/90 , C07D309/10
摘要： A choline salt crystal of (1S)-1,5-anhydro-1-[5-(azulen-2-ylmethyl)-2-hydroxyphenyl]-D-glucitol which shows an endothermic peak at 194 to 198° C. as measured by differential scanning calorimetry (DSC analysis) and shows main peaks at about 2θ (°) 5.58, 14.72, 16.80, 17.82, 21.02, and 22.46 as measured by X-ray powder diffraction. Thus, a crystal of an azulene compound can be produced which is in a single crystal form, has a constant quality, can be produced with good reproducibility, can be provided stably as a crystal of an drug substance for use in the preparation of a pharmaceutical and is excellent in storage stability.
摘要翻译：（1S）-1,5-脱水-1- [5-（薁-2-基甲基）-2-羟基苯基] -D-葡萄糖醇的胆碱盐晶体，其在194至198℃下显示吸热峰通过差示扫描量热法（DSC分析），并且通过X射线粉末衍射测量显示在约2θ（°）5.58,14.72,16.80,17.82,21.02和22.46处的主峰。因此，可以制造az烯化合物的结晶，其为单晶形式，具有恒定的质量，可以以良好的再现性制备，可以稳定地提供用作制备药物的药物的晶体储存稳定性优异。

6. 发明授权

US07868504B2 Resolver 有权
标题翻译：解决方案
公开(公告)号：US07868504B2
公开(公告)日：2011-01-11
申请号：US12106406
申请日：2008-04-21
申请人： Nakaba Kataoka , Keita Nakanishi
发明人： Nakaba Kataoka , Keita Nakanishi
IPC分类号： H02K24/00 , G01D5/245
CPC分类号： G01P3/488 , H02K1/24 , H02K11/225 , H02K24/00
摘要： A resolver rotor for a variable reluctance resolver includes a plurality of axially stacked rotor pieces. The rotor pieces are jointly fitted into one body. In the fitting of the rotor pieces, deformed portions are provided between a center of the radial thickness of the resolver rotor and a side surface thereof which is opposite to a stator-side surface thereof. The number of deformed portions is the same as that of projecting poles of the resolver rotor. The deformed portions are arranged at circumferential positions of peaks of the respective projecting poles. At those positions, concave portions are provided on the side surface to receive deformations caused by fitting the rotor pieces together. Thus, the stator-side surface of the resolver rotor is less affected by fitting of the rotor pieces together, preventing a reduction in the detection accuracy of the resolver.
摘要翻译：用于可变磁阻旋转变压器的旋转变压器转子包括多个轴向堆叠的转子件。转子片共同组装成一体。在转子件的装配中，变形部分设置在旋转变压器转子的径向厚度的中心和与其定子侧表面相对的侧表面之间。变形部的数量与旋转变压器转子的突出极的数量相同。变形部分布置在各个突出极的峰的圆周位置处。在这些位置处，在侧面上设置有凹部以容纳通过将转子片装配在一起而引起的变形。因此，旋转变压器转子的定子侧表面较少受到转子片的配合的影响，防止了旋转变压器的检测精度的降低。

7. 发明授权

US07827673B2 Resolver and manufacturing method of the same 有权
公开(公告)号：US07827673B2
公开(公告)日：2010-11-09
申请号：US12773999
申请日：2010-05-05
申请人： Nakaba Kataoka , Keita Nakanishi
发明人： Nakaba Kataoka , Keita Nakanishi
IPC分类号： H02K15/02
CPC分类号： H02K5/225 , G01D5/2013 , H02K3/522 , H02K11/225 , Y10T29/49009 , Y10T29/4902 , Y10T29/53143 , Y10T29/53157
摘要： In a resolver of a motor, a plurality of wires forming a plurality of coils arranged at a resolver stator portion are arranged at a wiring surface which is arranged at a terminal block of a connector portion and extends between an annular shape surface arranged substantially perpendicularly to a central axis at a core back of an insulator and a plurality of terminal pins, and are connected to a control unit via the terminal pins. Each of the wires of the resolver includes a slackened portion formed at a portion thereof between corresponding terminal pins and corresponding coils. The slackened portion is accommodated in a groove portion arranged at the wiring surface of the connector portion in order to minimize the possibility of damaging the wire improving reliability of the connection between the terminal pin and the coil.

8. 发明授权

US5573579A Method for producing friction material 失效
标题翻译：制造摩擦材料的方法
公开(公告)号：US5573579A
公开(公告)日：1996-11-12
申请号：US403108
申请日：1995-03-13
申请人： Keita Nakanishi , Takuo Ishihara
发明人： Keita Nakanishi , Takuo Ishihara
IPC分类号： F16D69/02 , C09K3/14
CPC分类号： F16D69/026
摘要： A method for producing friction material free of pill having at least 2 mm in shorter diameter comprising mixing dispersion medium and friction base comprising carbon fiber having weighted mean fiber length of at least 0.3 mm, binder and friction modifier to form a dispersion ranging in a solid content concentration of 0.5 to 50% by weight, filtering the dispersion, drying a filter cake and forming the cake.
摘要翻译：一种用于生产不含较短直径至少2mm的药丸的摩擦材料的方法，其包括混合分散介质和包含具有至少0.3mm的加权平均纤维长度的碳纤维的摩擦基，粘合剂和摩擦改进剂以形成在固体中的分散体含量浓度为0.5〜50重量％，过滤分散液，干燥滤饼并形成滤饼。

9. 发明授权

US07755231B2 Resolver and manufacturing method of the same 有权
标题翻译：解决方案和制造方法相同
公开(公告)号：US07755231B2
公开(公告)日：2010-07-13
申请号：US11971923
申请日：2008-01-10
申请人： Nakaba Kataoka , Keita Nakanishi
发明人： Nakaba Kataoka , Keita Nakanishi
IPC分类号： H02K3/50 , H02K15/10
CPC分类号： H02K5/225 , G01D5/2013 , H02K3/522 , H02K11/225 , Y10T29/49009 , Y10T29/4902 , Y10T29/53143 , Y10T29/53157
摘要： In a resolver of a motor, a plurality of wires forming a plurality of coils arranged at a resolver stator portion are arranged at a wiring surface which is arranged at a terminal block of a connector portion and extends between an annular shape surface arranged substantially perpendicularly to a central axis at a core back of an insulator and a plurality of terminal pins, and are connected to a control unit via the terminal pins. Each of the wires of the resolver includes a slackened portion formed at a portion thereof between corresponding terminal pins and corresponding coils. The slackened portion is accommodated in a groove portion arranged at the wiring surface of the connector portion in order to minimize the possibility of damaging the wire improving reliability of the connection between the terminal pin and the coil.
摘要翻译：在电动机的旋转变压器中，在布置在连接器部分的接线端子处的布线表面上布置了多个形成在旋转变压器定子部分上的多个线圈的导线，并在基本垂直于绝缘体的芯背的中心轴和多个端子引脚，并且经由端子引脚连接到控制单元。分解器的每根线包括形成在相应的端子销和相应线圈之间的部分处的松弛部分。松弛部分容纳在布置在连接器部分的布线表面处的凹槽部分中，以便最小化损坏导线的可能性，从而提高端子引脚和线圈之间的连接的可靠性。

10. 发明授权

US07635933B2 Resolver, method for manufacturing resolver, and device for mounting conductive wire to resolver 有权
标题翻译：解析器，解析器的制造方法，以及将导线安装到旋转变压器的装置
公开(公告)号：US07635933B2
公开(公告)日：2009-12-22
申请号：US11812421
申请日：2007-06-19
申请人： Yusuke Makino , Keita Nakanishi
发明人： Yusuke Makino , Keita Nakanishi
IPC分类号： H02K11/00
CPC分类号： H02K3/522 , H02K5/225 , H02K11/225 , H02K15/0075 , Y10T29/49009 , Y10T29/53157 , Y10T29/53235
摘要： After a winding machine connects a winding wire to a terminal pin, a slackening member is moved in a substantially horizontal direction substantially orthogonal to a direction of a terminal block being extended so as to be located on an orbit of the winding wire. Then, a led part of the winding wire radially between the terminal pin and teeth is extended to the teeth while in contact with a curved surface of a tip of the slackening member. That is, the led part is extended while bent in the substantially horizontal direction. After the winding wire is wound around the respective teeth, the slackening member is moved out of the orbit.
摘要翻译：在绕线机将绕组线连接到端子销之后，松弛构件在与正在延伸的端子块的方向大致正交的基本水平的方向上移动，以便位于绕组线的轨道上。然后，径向地在端子销和齿之间的绕组的引线部分在与松弛部件的尖端的弯曲表面接触的同时延伸到齿上。也就是说，在大致水平的方向弯曲时，引导部分被延伸。绕组绕线缠绕在相应的齿上之后，松弛构件被移出轨道。

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