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    • 3. 发明授权
    • Method of sterilizing sealed vial and apparatus for sealing the vial
    • 灭菌密封小瓶的方法和用于密封小瓶的装置
    • US5609819A
    • 1997-03-11
    • US499658
    • 1995-07-07
    • Katsumi ShimizuWashiro Honda
    • Katsumi ShimizuWashiro Honda
    • B65B55/14A61L2/06A61L2/08A61L2/12A61L2/24B65B55/02
    • A61L2/085A61L2/06A61L2/12
    • While a sealed vessel such as a vial having an inside plug such as a rubber stopper is conveyed, the sealed vessel is slanted by a slanting device until liquid medicine in the sealed vessel touches the inside plug. The sealed vessel is moved and simultaneously rotated by a rotating device while the vial is slanted. The liquid medicine in the sealed vessel is heated at a heating portion by heat energy such as infrared, fuel gas and microwave, so that the heated liquid medicine causes heat sterilization of the whole sealed vessel including the inside plug. Sterilization can be completely carried out by providing a heat-retaining portion, cooling portion and drying portion next to the heating portion. An infrared radiation thermometer is provided at the end of the heating portion to measure the temperature of the liquid medicine, so that the temperature of the liquid medicine in each sealed vessel may be controlled to a desired temperature.
    • 虽然输送了诸如具有内塞(例如橡胶塞)的小瓶的密封容器,但是密封容器通过倾斜装置倾斜,直到密封容器中的液体药物接触内塞。 当小瓶倾斜时,密封容器通过旋转装置移动并同时旋转。 密封容器中的液体药物通过红外线,燃料气体和微波等热能在加热部分加热,使得加热的液体药物对包括内塞的整个密封容器进行加热灭菌。 通过在加热部分附近设置保温部,冷却部和干燥部,能够完全灭菌。 在加热部分的末端设置红外线辐射温度计,以测量液体药物的温度,从而将每个密封容器中的液体药物的温度控制在所需温度。