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1. 发明授权

US07955676B2 Medical tubes 有权
标题翻译：医用管
公开(公告)号：US07955676B2
公开(公告)日：2011-06-07
申请号：US11791526
申请日：2005-11-25
申请人： Kouichi Igarashi , Sadamu Shirokuma , Ryoji Mori , Isamu Tateishi , Hitoshi Mori , Rie Ishii
发明人： Kouichi Igarashi , Sadamu Shirokuma , Ryoji Mori , Isamu Tateishi , Hitoshi Mori , Rie Ishii
IPC分类号： C08L23/10 , C08L23/02
CPC分类号： A61M39/08 , A61L29/041 , A61M25/0009 , C08L23/10 , C08L23/12 , C08L23/14 , C08L23/142 , Y10T428/13 , Y10T428/1397 , C08L2666/06
摘要： Medical tubes are well balanced in transparency, flexibility, heat resistance, scratch resistance and rubber elasticity.The medical tubes including a propylene polymer composition (A) that contains a polymer with propylene units, at least part of the polymer having an isotactic structure and the total of the propylene units of the polymer being in an amount of 65 to 82 mol % (the total of the structural units of the polymer in the composition is 100 mol %), and that satisfies the following (a1), (a2) and (b1): (a1) the modulus in tension is in the range of 5 to 25 MPa as determined in accordance with JIS K 6301; (a2) the penetration temperature is 120° C. or above as determined in accordance with JIS K 7196; and (b1) when a tube being made of the composition (A) and having an inner diameter of 2.1 mm, an outer diameter of 3.5 mm and a length of 20 cm is looped by inserting both ends thereof into a hollow jig having a hole 10 mm in diameter and 5 mm in height and, then, the both ends of the tube are pulled down until a kink occurs in the loop, the distance H from the upper surface of the jig to the upper end of the loop is not more than 60 mm.
摘要翻译：医疗管在透明度，柔韧性，耐热性，耐刮擦性和橡胶弹性方面均衡。医疗管包括丙烯聚合物组合物（A），其含有具有丙烯单元的聚合物，所述聚合物的至少一部分具有全同立构结构，聚合物的丙烯单元的总量为65〜82摩尔％组合物中的聚合物的结构单元的总和为100摩尔％），满足以下（a1），（a2）和（b1）：（a1）张力的模量为5〜25的范围 MPa，根据JIS K 6301测定; （a2）根据JIS K 7196测定的穿透温度为120℃以上; 和（b1）当由组合物（A）制成并且内径为2.1mm，外径为3.5mm和长度为20cm的管时，将其两端插入具有孔的中空夹具中，直径为10毫米，高度为5毫米，然后将管的两端向下拉，直到在环中发生扭结，从夹具上表面到环的上端的距离H不大超过60毫米。

2. 发明申请

US20080215016A1 Medical Tubes 有权
标题翻译：医用管
公开(公告)号：US20080215016A1
公开(公告)日：2008-09-04
申请号：US11791526
申请日：2005-11-25
申请人： Kouichi Igarashi , Sadamu Shirokuma , Ryoji Mori , Isamu Tateishi , Hitoshi Mori , Rie Ishii
发明人： Kouichi Igarashi , Sadamu Shirokuma , Ryoji Mori , Isamu Tateishi , Hitoshi Mori , Rie Ishii
IPC分类号： A61M25/00
CPC分类号： A61M39/08 , A61L29/041 , A61M25/0009 , C08L23/10 , C08L23/12 , C08L23/14 , C08L23/142 , Y10T428/13 , Y10T428/1397 , C08L2666/06
摘要： Medical tubes are well balanced in transparency, flexibility, heat resistance, scratch resistance and rubber elasticity.The medical tubes including a propylene polymer composition (A) that contains a polymer with propylene units, at least part of the polymer having an isotactic structure and the total of the propylene units of the polymer being in an amount of 65 to 82 mol % (the total of the structural units of the polymer in the composition is 100 mol %), and that satisfies the following (a1), (a2) and (b1): (a1) the modulus in tension is in the range of 5 to 25 MPa as determined in accordance with JIS K 6301; (a2) the penetration temperature is 120° C. or above as determined in accordance with JIS K 7196; and (b1) when a tube being made of the composition (A) and having an inner diameter of 2.1 mm, an outer diameter of 3.5 mm and a length of 20 cm is looped by inserting both ends thereof into a hollow jig having a hole 10 mm in diameter and 5 mm in height and, then, the both ends of the tube are pulled down until a kink occurs in the loop, the distance H from the upper surface of the jig to the upper end of the loop is not more than 60 mm.
摘要翻译：医疗管在透明度，柔韧性，耐热性，耐刮擦性和橡胶弹性方面均衡。医疗管包括丙烯聚合物组合物（A），其含有具有丙烯单元的聚合物，所述聚合物的至少一部分具有全同立构结构，聚合物的丙烯单元的总量为65〜82摩尔％组合物中的聚合物的结构单元的总和为100摩尔％），满足以下（a1），（a2）和（b1）：（a1）张力的模量为5〜25的范围 MPa，根据JIS K 6301测定; （a2）根据JIS K 7196测定的穿透温度为120℃以上; 和（b1）当由组合物（A）制成并且内径为2.1mm，外径为3.5mm和长度为20cm的管时，将其两端插入具有孔的中空夹具中，直径为10毫米，高度为5毫米，然后将管的两端向下拉，直到在环中发生扭结，从夹具上表面到环的上端的距离H不大超过60毫米。

3. 发明授权

US07914867B2 Medical gas barrier film and medical bag using the same 有权
标题翻译：医用气体阻隔膜及使用该药物的医疗袋
公开(公告)号：US07914867B2
公开(公告)日：2011-03-29
申请号：US11665384
申请日：2005-10-13
申请人： Hitoshi Mori , Yasushi Morimoto , Kenji Konishi , Isamu Tateishi
发明人： Hitoshi Mori , Yasushi Morimoto , Kenji Konishi , Isamu Tateishi
IPC分类号： B32B1/02 , B32B27/00 , B32B27/32 , B32B27/34 , B32B27/36 , B32B27/25
CPC分类号： A61J1/10 , A61M2207/00 , B32B7/12 , B32B25/08 , B32B25/14 , B32B27/08 , B32B27/16 , B32B27/32 , B32B27/325 , B32B27/34 , B32B27/36 , B32B2255/10 , B32B2255/20 , B32B2274/00 , B32B2307/306 , B32B2307/31 , B32B2307/412 , B32B2307/514 , B32B2307/558 , B32B2307/7242 , B32B2439/46 , B32B2439/80 , Y10T428/13 , Y10T428/1303 , Y10T428/1307 , Y10T428/1334 , Y10T428/1352 , Y10T428/1359 , Y10T428/1379 , Y10T428/2495 , Y10T428/2817 , Y10T428/31725 , Y10T428/31765 , Y10T428/31786 , Y10T428/31797 , Y10T428/31855 , Y10T428/31909
摘要： The object of the present invention is to provide a gas barrier film suitable for medical uses, which is excellent in gas and vapor properties and can prevent ingredients of an adhesive and the like from eluting even after heating and sterilizing treatment, and a medical bag using the gas barrier film. A medical gas barrier film of the present invention comprises a multilayer gas barrier film 10 including a deposition oriented polyester layer 11 having a deposited layer 13 of an inorganic oxide on one surface, an oriented polyamide layer 15 adhered to the surface of the deposited layer 13 and a polyethylene layer 17 adhered to the surface on the opposite side to an adhered surface 15a of the oriented polyamide layer 15, and a multilayer substrate film 22 including a cyclic olefin polymer layer 25, an elastomer layers 24, 26 and a heat sealing layer 23, and the multilayer substrate film 22 is adhered to an other surface 11b on the opposite side of the deposited layer of the deposition oriented polyester layer 11.
摘要翻译：本发明的目的是提供一种适用于医疗用途的气体阻隔膜，其气体和蒸汽性能优异，并且即使在加热灭菌处理后也可以防止粘合剂等的成分洗脱，以及使用阻气膜。本发明的医疗用气体阻隔膜包括：多层阻气膜10，其包括在一个表面上具有无机氧化物的沉积层13的沉积取向聚酯层11，附着到沉积层13的表面的取向聚酰胺层15 以及与取向聚酰胺层15的粘合面15a相反一侧的表面粘附的聚乙烯层17，以及包含环状烯烃聚合物层25，弹性体层24,26和热封层 23，并且多层基板膜22粘附到沉积取向聚酯层11的沉积层的相对侧上的另一个表面11b。

4. 发明申请

US20100092446A1 DRUG SOLUTION HAVING REDUCED DISSOLVED OXYGEN CONTENT, METHOD OF PRODUCING THE SAME AND DRUG SOLUTION CONTAINING UNIT HAVING REDUCED DISSOLVED OXYGEN CONTENT 有权
标题翻译：具有降低的溶解氧含量的药物溶液，其生产方法和包含具有降低的溶解氧含量的单元的药物溶液
公开(公告)号：US20100092446A1
公开(公告)日：2010-04-15
申请号：US12447101
申请日：2007-10-25
申请人： Nobuaki Sumiyoshi , Isamu Tateishi , Hitoshi Mori , Yasushi Morimoto
发明人： Nobuaki Sumiyoshi , Isamu Tateishi , Hitoshi Mori , Yasushi Morimoto
IPC分类号： A61K31/4415 , A61K31/198 , A61K31/07 , A61K31/59 , A61K31/375 , A61K31/519 , A61K31/455 , A61P43/00
CPC分类号： A61J1/10 , A61J1/2093 , A61K9/08
摘要： It is an object of the present invention to provide a drug solution which has a reduced dissolved oxygen content and is less susceptible to oxidative degradation and highly stable over time, a production method therefor, and a drug solution containing pack which is capable of maintaining the dissolved oxygen content of a drug solution at a reduced level, less susceptible to oxidative degradation of the drug solution and highly stable over time. To achieve the aforementioned object, the reduced-dissolved-oxygen-content drug solution is produced by filling and sealing the drug solution in a drug solution container (15) formed of a plastic material having an oxygen permeability of not lower than 200 cm3/m2·24 h·atm at 25° C. at 60% RH within 12 hours after a steam sterilization process or a hot water sterilization process and having a steady-state oxygen permeability of not higher than 100 cm3/m2·24 h·atm at 25° C. at 60% RH, subjecting the drug solution container to the steam sterilization process or the hot water sterilization process, and storing the drug solution container in an environment having deoxidization means for reducing the dissolved oxygen concentration of the drug solution to not higher than 2 ppm when the oxygen permeability of the plastic material reaches the steady-state level.
摘要翻译：本发明的目的是提供一种药物溶液，其溶解氧含量降低，并且不易氧化降解，随时间稳定性高，其制备方法和药物溶液包装，其能够维持药物溶液的氧含量降低，对药物溶液的氧化降解敏感，并且随着时间的推移高度稳定。为了实现上述目的，通过将药液填充并密封在由氧透过度不低于200cm 3 / m 2的塑料材料形成的药液容器（15）中来制造还原溶解氧含量药物溶液 ·蒸汽灭菌处理或热水灭菌处理后的12小时内，在25℃，60％RH的情况下，在25℃，24h·atm，稳态透氧度不高于100cm 3 / m 2·24h·atm 在60％RH下25℃，对药液容器进行蒸汽消毒处理或热水灭菌处理，并将药液容器储存在具有用于将药液溶解氧浓度降低的脱氧装置的环境中当塑料材料的透氧性达到稳态水平时，高于2ppm。

5. 发明申请

US20090032426A1 Drug Solution Container Package and Method for Manufacturing the Same 有权
标题翻译：药物溶液容器包装及其制造方法
公开(公告)号：US20090032426A1
公开(公告)日：2009-02-05
申请号：US11911644
申请日：2006-04-19
申请人： Isamu Tateishi , Hitoshi Mori , Yasushi Morimoto
发明人： Isamu Tateishi , Hitoshi Mori , Yasushi Morimoto
IPC分类号： A61J1/05 , B65B55/10
CPC分类号： B32B27/32 , A61J1/10 , A61M2207/00 , Y10T428/1352 , Y10T428/1379 , Y10T428/1383
摘要： An object of this invention is to provide a drug solution container package, which can restrain degradation of a drug solution, proliferation of microbes, etc. accompanying the transmission of oxygen in a high degree while maintaining characteristics required of plastic drug solution containers such as heat resistance, impact resistance, pliability, transparency, and resistance against elution of plastic forming material, and to provide a method for manufacturing the drug solution container package. In the present invention, to achieve the above object, a drug solution is contained and sealed in a plastic drug solution container having an oxygen gas transmission rate (25° C., 60% RH) of not less than 200 cm3/m2·24h·atm within twelve hours after being subject to steam sterilization or hot water sterilization, and having an oxygen gas transmission rate (25° C., 60% RH) of not more than 100 cm3/m2·24 h·atm when the oxygen gas transmission rate is in a steady state, and thereafter the plastic drug solution container is steam sterilized or hot water sterilized and then are contained and sealed along with an oxygen scavenger in an outer pouch having an oxygen barrier property.
摘要翻译：本发明的目的是提供一种药液溶液容器包装，其能够在保持塑料药液容器例如热量所需的特性的同时高效地抑制药物溶液的降解，微生物等的增殖，伴随氧传递。电阻，耐冲击性，柔韧性，透明性和耐洗脱性，并提供制造药液容器包装的方法。在本发明中，为了达到上述目的，将药液包含并密封在氧气透过率（25℃，60％RH）为200cm 3 / m 2以上的塑料药液容器中，24h 在进行蒸汽灭菌或热水灭菌后的十二个小时内，当氧气气体的氧气透过率（25℃，60％RH）为不大于100立方厘米/平方米时，透射率处于稳定状态，然后将塑料药液容器进行蒸汽灭菌或热水灭菌，然后与含氧阻隔性的外袋中的除氧剂一起被包含并密封。

6. 发明授权

US08163361B2 Pliable plastic film and container using the same 有权
标题翻译：柔韧塑料薄膜和容器使用相同
公开(公告)号：US08163361B2
公开(公告)日：2012-04-24
申请号：US12659828
申请日：2010-03-23
申请人： Isamu Tateishi , Hitoshi Mori
发明人： Isamu Tateishi , Hitoshi Mori
IPC分类号： B29D22/00 , A61B19/00
CPC分类号： B32B27/32 , A61J1/2024 , A61J1/2093 , C08L23/12 , C08L23/142 , Y10T428/1334 , Y10T428/1352 , Y10T428/24843 , C08L2666/06
摘要： A pliable plastic film according to the present invention comprises a heat sealable sealing layer, wherein the sealing layer is made of a mixture of a propylene-α-olefin random copolymer having a crystalline melting point Tm of 135 to 145° C. and a polypropylene (PP) homopolymer having a crystalline melting point Tm of higher than 160° C.
摘要翻译：根据本发明的柔韧塑料膜包括可热封的密封层，其中密封层由结晶熔点Tm为135-145℃的丙烯-α-烯烃无规共聚物和聚丙烯（PP）均聚物，其结晶熔点Tm高于160℃

7. 发明申请

US20100179504A1 Pliable plastic film and container using the same 有权
标题翻译：柔韧塑料薄膜和容器使用相同
公开(公告)号：US20100179504A1
公开(公告)日：2010-07-15
申请号：US12659828
申请日：2010-03-23
申请人： Isamu Tateishi , Hitoshi Mori
发明人： Isamu Tateishi , Hitoshi Mori
IPC分类号： A61B19/00
CPC分类号： B32B27/32 , A61J1/2024 , A61J1/2093 , C08L23/12 , C08L23/142 , Y10T428/1334 , Y10T428/1352 , Y10T428/24843 , C08L2666/06
摘要： A pliable plastic film according to the present invention comprises a heat sealable sealing layer, wherein the sealing layer is made of a mixture of a propylene-α-olefin random copolymer having a crystalline melting point Tm of 135 to 145° C. and a polypropylene (PP) homopolymer having a crystalline melting point Tm of higher than 160° C.
摘要翻译：根据本发明的柔韧塑料膜包括可热封的密封层，其中密封层由结晶熔点Tm为135-145℃的丙烯-α-烯烃无规共聚物和聚丙烯（PP）均聚物，其结晶熔点Tm高于160℃。

8. 发明申请

US20080176016A1 Pliable plastic film and container using the same 审中-公开
标题翻译：柔韧塑料薄膜和容器使用相同
公开(公告)号：US20080176016A1
公开(公告)日：2008-07-24
申请号：US11657019
申请日：2007-01-24
申请人： Isamu Tateishi , Hitoshi Mori
发明人： Isamu Tateishi , Hitoshi Mori
IPC分类号： B32B7/06 , B32B27/08
CPC分类号： B32B27/32 , A61J1/2024 , A61J1/2093 , C08L23/12 , C08L23/142 , Y10T428/1334 , Y10T428/1352 , Y10T428/24843 , C08L2666/06
摘要： A pliable plastic film according to the present invention comprises a heat sealable sealing layer, wherein the sealing layer is made of a mixture of a propylene-α-olefin random copolymer having a crystalline melting point Tm of 135 to 145° C. and a polypropylene (PP) homopolymer having a crystalline melting point Tm of higher than 160° C.
摘要翻译：根据本发明的柔韧塑料膜包括可热密封的密封层，其中密封层由具有135的结晶熔点T m的丙烯-α-烯烃无规共聚物的混合物制成至145℃的聚丙烯（PP）均聚物，其结晶熔点T m高于160℃

9. 发明申请

US20080063825A1 Medical Gas Barrier Film and Medical Bag Using the Same 有权
标题翻译：医用气体阻隔膜和医疗袋使用它
公开(公告)号：US20080063825A1
公开(公告)日：2008-03-13
申请号：US11665384
申请日：2005-10-13
申请人： Hitoshi Mori , Yasushi Morimoto , Kenji Konishi , Isamu Tateishi
发明人： Hitoshi Mori , Yasushi Morimoto , Kenji Konishi , Isamu Tateishi
IPC分类号： B32B1/08 , B32B7/02 , B32B7/12
CPC分类号： A61J1/10 , A61M2207/00 , B32B7/12 , B32B25/08 , B32B25/14 , B32B27/08 , B32B27/16 , B32B27/32 , B32B27/325 , B32B27/34 , B32B27/36 , B32B2255/10 , B32B2255/20 , B32B2274/00 , B32B2307/306 , B32B2307/31 , B32B2307/412 , B32B2307/514 , B32B2307/558 , B32B2307/7242 , B32B2439/46 , B32B2439/80 , Y10T428/13 , Y10T428/1303 , Y10T428/1307 , Y10T428/1334 , Y10T428/1352 , Y10T428/1359 , Y10T428/1379 , Y10T428/2495 , Y10T428/2817 , Y10T428/31725 , Y10T428/31765 , Y10T428/31786 , Y10T428/31797 , Y10T428/31855 , Y10T428/31909
摘要： The object of the present invention is to provide a gas barrier film suitable for medical uses, which is excellent in gas and vapor properties and can prevent ingredients of an adhesive and the like from eluting even after heating and sterilizing treatment, and a medical bag using the gas barrier film. A medical gas barrier film of the present invention comprises a multilayer gas barrier film 10 including a deposition oriented polyester layer 11 having a deposited layer 13 of an inorganic oxide on one surface, an oriented polyamide layer 15 adhered to the surface of the deposited layer 13 and a polyethylene layer 17 adhered to the surface on the opposite side to an adhered surface 15a of the oriented polyamide layer 15, and a multilayer substrate film 22 including a cyclic olefin polymer layer 25, an elastomer layers 24, 26 and a heat sealing layer 23, and the multilayer substrate film 22 is adhered to an other surface 11b on the opposite side of the deposited layer of the deposition oriented polyester layer 11.
摘要翻译：本发明的目的是提供一种适用于医疗用途的气体阻隔膜，其气体和蒸汽性能优异，并且即使在加热灭菌处理后也可以防止粘合剂等的成分洗脱，以及使用阻气膜。本发明的医疗用气体阻隔膜包括：多层阻气膜10，其包括在一个表面上具有无机氧化物的沉积层13的沉积取向聚酯层11，附着到沉积层13的表面的取向聚酰胺层15 以及与取向聚酰胺层15的粘合面15a相反一侧的表面粘附的聚乙烯层17，以及包含环状烯烃聚合物层25，弹性体层24,26和热封的多层基板膜22 层23，并且多层基板膜22粘附到沉积取向聚酯层11的沉积层的相对侧上的另一表面11b。

10. 发明授权

US09901513B2 Drug solution having reduced dissolved oxygen content, method of producing the same and drug solution containing unit having reduced dissolved oxygen content 有权
公开(公告)号：US09901513B2
公开(公告)日：2018-02-27
申请号：US12447101
申请日：2007-10-25
申请人： Nobuaki Sumiyoshi , Isamu Tateishi , Hitoshi Mori , Yasushi Morimoto
发明人： Nobuaki Sumiyoshi , Isamu Tateishi , Hitoshi Mori , Yasushi Morimoto
IPC分类号： A61J1/00 , A61K31/07 , A61J1/10 , A61K9/08 , A61J1/20
CPC分类号： A61J1/10 , A61J1/2093 , A61K9/08
摘要： A reduced-dissolved-oxygen-content drug solution produced by filling and sealing the drug solution in a drug solution container (15) formed of a plastic material having an oxygen permeability of not lower than 200 cm3/m2·24 h·atm at 25° C. at 60% RH within 12 hours after a steam sterilization process or a hot water sterilization process and having a steady-state oxygen permeability of not higher than 100 cm3/m2·24 h·atm at 25° C. at 60% RH, subjecting the drug solution container to the steam sterilization process or the hot water sterilization process, and storing the drug solution container in an environment having deoxidization means for reducing the dissolved oxygen concentration of the drug solution to not higher than 2 ppm when the oxygen permeability of the plastic material reaches the steady-state level.

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