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1. 发明授权

US5661738A Solid-state laser amplifying apparatus and solid-state laser apparatus capable of oscillating high-power laser beam under stable condition 失效
标题翻译：固态激光放大装置和稳态条件下能够振荡大功率激光束的固态激光装置
公开(公告)号：US5661738A
公开(公告)日：1997-08-26
申请号：US543070
申请日：1995-10-13
申请人： Koji Yasui , Tetsuo Kojima
发明人： Koji Yasui , Tetsuo Kojima
IPC分类号： H01S3/042 , H01S3/094 , H01S3/0941 , H01S3/10 , H01S3/16
CPC分类号： H01S3/061 , H01S3/0941 , H01S3/025 , H01S3/0407 , H01S3/042 , H01S3/094057 , H01S3/09408
摘要： In a solid-state laser amplifying apparatus and a solid-state laser apparatus, a high-power laser beam can be produced in a high efficiency under stable condition. The solid-state laser amplifying apparatus is comprised of a solid-state element containing an activated solid medium; a flow tube for causing a cooling medium used to cool the solid-state element to flow therethrough; a light condensing device arranged so as to surround the solid-state element, for holding the flow tube by directly, or indirectly sandwiching the flow tube, an inner surface of which is formed as a diffusion/reflection surface; an excitation light source arranged outside the light condensing device, for emitting excitation light used to excite the solid-state element; and an opening portion provided with the light condensing device, for conducting the excitation light.
摘要翻译：在固体激光放大装置和固体激光装置中，能够在稳定的条件下高效率地制造高功率激光束。固体激光放大装置由含有活化的固体介质的固态元件组成; 用于使用于冷却固态元件的冷却介质流过其中的流管; 一个聚光装置，被布置成围绕固态元件，用于通过直接地或间接地夹持其内表面作为扩散/反射表面的流动管夹持流管; 激发光源，其布置在所述聚光装置的外部，用于发射用于激发所述固态元件的激发光; 以及设置有聚光装置的开口部分，用于传导激发光。

2. 发明授权

US5359616A Solid state laser apparatus and laser machining apparatus 失效
标题翻译：固态激光装置和激光加工装置
公开(公告)号：US5359616A
公开(公告)日：1994-10-25
申请号：US114086
申请日：1993-08-31
申请人： Koji Yasui , Tetsuo Kojima , Takashi Yamamoto , Akira Ishimori , Kuniaki Iwashiro
发明人： Koji Yasui , Tetsuo Kojima , Takashi Yamamoto , Akira Ishimori , Kuniaki Iwashiro
IPC分类号： H01S3/06 , B23K26/06 , H01S3/04 , H01S3/042 , H01S3/07 , H01S3/08 , H01S3/093 , H01S3/0941 , H01S3/105 , H01S3/23 , H01S3/14
CPC分类号： H01S3/0931 , B23K26/0622 , H01S2301/20 , H01S2301/206 , H01S3/0407 , H01S3/042 , H01S3/061 , H01S3/0617 , H01S3/07 , H01S3/08 , H01S3/08063 , H01S3/08068 , H01S3/08072 , H01S3/08081 , H01S3/0941 , H01S3/23 , H01S3/2308
摘要： A solid state laser apparatus is provided to generate a high quality and high power laser beam, and a laser machining apparatus is provided to perform laser machining by a laser beam generated from the solid state laser apparatus. In the solid state laser apparatus, a laser resonator includes a solid state component cooled in a cylindrical pipe by contacting liquid which is introduced through an inflow opening and discharged through an outflow opening, the solid state component having larger refractive index than that of the liquid, a light source turned ON by a power source to excite the solid state component, and an optical system transmitting light from the light source to the solid state component. Further, a surface roughness of the solid state component is adjusted so as to adjust an excitation distribution in a section of the solid state component. The solid state component further includes moving means for moving a reflection mirror and a condensing lens in a direction of an optical axis of the laser resonator, and a housing accommodating an image transferring optical system. A laser beam is generated from the laser resonator, and is externally derived and used to perform the laser machining.
摘要翻译：提供固体激光装置以产生高质量和高功率的激光束，并且提供激光加工装置以通过由固态激光装置产生的激光束进行激光加工。在固体激光装置中，激光谐振器包括通过使通过流入开口引入并通过流出开口排出的液体接触在圆筒形管中冷却的固态成分，固体成分的折射率比液体的折射率大通过电源将光源接通以激发固体成分，以及将光从光源透射到固体成分的光学系统。此外，调整固体成分的表面粗糙度，以调整固体成分的截面中的激发分布。固态分量还包括用于在激光谐振器的光轴的方向上移动反射镜和聚光透镜的移动装置，以及容纳图像转印光学系统的壳体。从激光谐振器产生激光束，并从外部衍生并用于执行激光加工。

3. 发明授权

US07142354B2 Wavelength conversion method, wavelength conversion device, and laser beam machine 有权
标题翻译：波长转换方法，波长转换装置和激光束机
公开(公告)号：US07142354B2
公开(公告)日：2006-11-28
申请号：US10511170
申请日：2001-12-12
申请人： Tetsuo Kojima , Susumu Konno , Shuichi Fujikawa , Koji Yasui , Takatomo Sasaki , Yusuke Mori , Masashi Yoshimura
发明人： Tetsuo Kojima , Susumu Konno , Shuichi Fujikawa , Koji Yasui , Takatomo Sasaki , Yusuke Mori , Masashi Yoshimura
IPC分类号： G02F1/35 , H01S3/108
CPC分类号： G02F1/3501 , G02F2001/3505
摘要： In a wavelength converting method, an ambient that is in contact with a surface of a non-linear optical crystal from which wavelength-converted light is outputted is a gas that is lower in content of nitrogen than air. A wavelength converting device includes a device for controlling the ambient in contact with a surface of the non-linear optical crystal from which the wavelength-converted light is outputted so the ambient is lower in nitrogen than air. A laser machining device includes the wavelength converting device.
摘要翻译：在波长转换方法中，与输出波长转换光的非线性光学晶体的表面接触的环境是氮含量低于空气的气体。波长转换装置包括用于控制与非线性光学晶体的表面接触的环境的装置，从该波长转换光输出波长转换的光，使得氮气中的环境比空气低。激光加工装置包括波长转换装置。

4. 发明授权

US5892789A Solid-state laser apparatus 失效
标题翻译：固态激光装置
公开(公告)号：US5892789A
公开(公告)日：1999-04-06
申请号：US899889
申请日：1997-07-24
申请人： Koji Yasui , Takafumi Kawai , Tetsuo Kojima , Susumu Konno
发明人： Koji Yasui , Takafumi Kawai , Tetsuo Kojima , Susumu Konno
IPC分类号： H01S3/07 , H01S3/08 , H01S3/091 , H01S3/0941 , H01S3/10 , H01S3/109 , H01S3/136 , H01S3/16 , H01S3/23 , H01S3/14
CPC分类号： H01S3/025 , H01S3/07 , H01S3/10 , H01S3/0407 , H01S3/042 , H01S3/08072 , H01S3/093 , H01S3/094057 , H01S3/0941 , H01S3/109
摘要： A solid-state laser apparatus comprises a plurality of solid-state materials each having an active solid-state medium and arranged in a row with a predetermined space on an optical axis of light incident thereon. An optical rotation material and an angle adjusting instrument for adjusting an angle between the optical rotation material and the optical axis of incident light are disposed in at least a space selected from among the plural spaces. The laser apparatus further comprises a laser optical system for extracting a laser beam emitted by the plural solid-state materials.
摘要翻译：固体激光装置包括多个固态材料，每个固态材料具有活性固态介质，并且在入射到其上的光的光轴上以预定的空间排成一行。用于调整光旋转材料与入射光的光轴之间的角度的光学旋转材料和角度调节装置设置在从多个空间中选择的至少一个空间中。激光装置还包括用于提取由多个固态材料发射的激光束的激光光学系统。

5. 发明申请

US20050225837A1 Wavelength conversion method, wavelength conversion device, and laser beam machine 有权
标题翻译：波长转换方法，波长转换装置和激光束机
公开(公告)号：US20050225837A1
公开(公告)日：2005-10-13
申请号：US10511170
申请日：2001-12-12
申请人： Tetsuo Kojima , Susumu Konno , Shuichi Fujikawa , Koji Yasui , Takatomo Sasaki , Yusuke Mori , Masashi Yoshimura
发明人： Tetsuo Kojima , Susumu Konno , Shuichi Fujikawa , Koji Yasui , Takatomo Sasaki , Yusuke Mori , Masashi Yoshimura
IPC分类号： G02F1/35 , G02F2/02
CPC分类号： G02F1/3501 , G02F2001/3505
摘要： In a wavelength converting method, an ambient that is in contact with a surface of a non-linear optical crystal from which wavelength-converted light is outputted is a gas that is lower in content of nitrogen than air. A wavelength converting device includes a device for controlling the ambient in contact with a surface of the non-linear optical crystal from which the wavelength-converted light is outputted so the ambient is lower in nitrogen than air. A laser machining device includes the wavelength converting device.
摘要翻译：在波长转换方法中，与输出波长转换光的非线性光学晶体的表面接触的环境是氮含量低于空气的气体。波长转换装置包括用于控制与非线性光学晶体的表面接触的环境的装置，从该波长转换光输出波长转换的光，使得氮气中的环境比空气低。激光加工装置包括波长转换装置。

6. 发明授权

US5889808A Photoexcitation solid laser amplifier photoexcitation solid laser unit and solid laser excitation method 失效
标题翻译：激光激光激光激光器激光激光单元和固体激光激发法
公开(公告)号：US5889808A
公开(公告)日：1999-03-30
申请号：US825048
申请日：1997-03-27
申请人： Tetsuo Kojima , Koji Yasui
发明人： Tetsuo Kojima , Koji Yasui
IPC分类号： H01S3/042 , H01S3/04 , H01S3/094 , H01S3/0941
CPC分类号： H01S3/0941 , H01S3/0407 , H01S3/042 , H01S3/094057
摘要： To inexpensively and in a simple configuration provide a solid laser amplifier and a solid laser unit capable of generating a high output and high quality laser beam, the unit includes a solid laser medium 5A containing active solid media; a flow tube 14 or the like allowing a cooling medium 24 for cooling the solid laser medium 5A; and a laser array 12 so controlled in temperature as to emit an excitation light 9 for exciting the solid laser medium 5A, the wavelength of which lies within the absorption spectra of a solid laser medium 5A yet does not coincide with that of the absorption spectrum peak of a solid laser medium 5A.
摘要翻译：为了廉价并且以简单的配置提供了能够产生高输出和高质量激光束的固体激光放大器和固体激光器单元，该单元包括含有活性固体介质的固体激光介质5A; 流动管14等，用于冷却固体激光介质5A的冷却介质24; 以及如此控制的激光阵列12，以发射用于激发固体激光介质5A的激发光9，其激光位于固体激光介质5A的吸收光谱内，但与吸收光谱峰的波长不一致的固体激光介质5A。

7. 发明授权

US08787042B2 DC power supply including arrangement to reduce switching loss and a snubber circuit to suppress surge voltages 有权
标题翻译：直流电源包括用于减少开关损耗的装置和缓冲电路以抑制浪涌电压
公开(公告)号：US08787042B2
公开(公告)日：2014-07-22
申请号：US13367653
申请日：2012-02-07
申请人： Yuichiro Nozaki , Tetsuo Kojima , Masafumi Makino
发明人： Yuichiro Nozaki , Tetsuo Kojima , Masafumi Makino
IPC分类号： H02M3/335 , H02M1/34
CPC分类号： H02M3/3378 , Y02B70/1433
摘要： In a DC power supply in which a DC power source and a transformer are connected via a power conversion circuit and a secondary winding of the transformer is connected to a load via a rectifier diode bridge and a filter circuit to supply power to the load, a resonance reactor is provided on an output side of the transformer, a resonant switch circuit including a parallel circuit of a diode and a semiconductor switch and a resonant capacitor is connected in parallel to the rectifier diode bridge and a snubber circuit including a snubber capacitor, a snubber diode and a diode for discharge is connected to a serial resonant circuit including the resonance reactor and the resonant capacitor in the resonant switch circuit to absorb a surge voltage.
摘要翻译：在其中直流电源和变压器通过功率转换电路连接的直流电源和变压器的次级绕组经由整流二极管桥和滤波电路连接到负载以向负载供电，谐振电抗器设置在变压器的输出侧，包括二极管和半导体开关的并联电路和谐振电容器的谐振开关电路并联连接到整流二极管桥和包括缓冲电容器的缓冲电路，缓冲二极管和用于放电的二极管连接到包括谐振电抗器和谐振开关电路中的谐振电容器的串联谐振电路以吸收浪涌电压。

8. 发明申请

US20130330345A1 MULTI-SPECIFIC ANTIGEN-BINDING MOLECULE HAVING ALTERNATIVE FUNCTION TO FUNCTION OF BLOOD COAGULATION FACTOR VIII 有权
标题翻译：具有替代功能的多特异性抗原结合分子对血液凝血因子VIII的功能
公开(公告)号：US20130330345A1
公开(公告)日：2013-12-12
申请号：US13885421
申请日：2011-11-17
申请人： Tomoyuki Igawa , Zenjiro Sampei , Tetsuo Kojima , Tetsuhiro Soeda , Atsushi Muto , Takehisa Kitazawa , Yukiko Nishida , Chifumi Imai , Tsukasa Suzuki , Kazutaka Yoshihashi
发明人： Tomoyuki Igawa , Zenjiro Sampei , Tetsuo Kojima , Tetsuhiro Soeda , Atsushi Muto , Takehisa Kitazawa , Yukiko Nishida , Chifumi Imai , Tsukasa Suzuki , Kazutaka Yoshihashi
IPC分类号： C07K16/40
CPC分类号： C07K16/40 , C07K16/36 , C07K2317/31 , C07K2317/51 , C07K2317/56 , C07K2317/565 , C07K2317/75 , C07K2317/76 , C07K2317/94
摘要： Various bispecific antibodies that specifically bind to both blood coagulation factor IX/activated blood coagulation factor IX and blood coagulation factor X and functionally substitute for the cofactor function of blood coagulation factor VIII, that is, the function to promote activation of blood coagulation factor X by activated blood coagulation factor IX, were produced. From these antibodies, multispecific antigen-binding molecules having a high activity of functionally substituting for blood coagulation factor VIII were successfully discovered.
摘要翻译：各种双特异性抗体特异性结合血液凝固因子IX /活化血液凝固因子IX和血液凝固因子X，并功能取代血液凝固因子VIII的辅因子功能，即促进凝血因子X活化的功能活化血液凝固因子IX。从这些抗体中，成功发现了具有高功能取代凝血因子VIII活性的多特异性抗原结合分子。

9. 发明授权

US08597911B2 Process for producing antibodies 失效
标题翻译：生产抗体的方法
公开(公告)号：US08597911B2
公开(公告)日：2013-12-03
申请号：US10560098
申请日：2004-06-11
申请人： Taro Miyazaki , Tetsuo Kojima
发明人： Taro Miyazaki , Tetsuo Kojima
IPC分类号： C12N15/13
CPC分类号： C07K16/468 , C07K16/00 , C07K16/2866 , C07K2317/626 , C12N2510/02
摘要： Focusing on the fact that antibody molecules with one H chain are not secreted when using the “knobs-into-holes” method, the present inventors revealed that desired bispecific antibodies can be preferentially formed by first expressing the H and L chains of one arm, and then suppressing their expression, followed by expressing the H and L chains of the other arm so that first desired HL molecules (HaLa and HbLb) are constructed, and then the H chains are paired with each other (H2L2). The present invention was thus completed.
摘要翻译：关注当使用“旋钮孔”方法时，不分泌具有一个H链的抗体分子的事实，本发明人揭示了可以通过首先表达一个臂的H和L链来优先形成所需的双特异性抗体，然后抑制其表达，然后表达另一臂的H链和L链，使得构建第一所需的HL分子（HaLa和HbLb），然后H链彼此配对（H2L2）。从而完成了本发明。

10. 发明申请

US20120224396A1 DC POWER SUPPLY 有权
标题翻译：直流电源
公开(公告)号：US20120224396A1
公开(公告)日：2012-09-06
申请号：US13367653
申请日：2012-02-07
申请人： Yuichiro NOZAKI , Tetsuo Kojima , Masafumi Makino
发明人： Yuichiro NOZAKI , Tetsuo Kojima , Masafumi Makino
IPC分类号： H02M3/335
CPC分类号： H02M3/3378 , Y02B70/1433
摘要： In a DC power supply in which a DC power source and a transformer are connected via a power conversion circuit and a secondary winding of the transformer is connected to a load via a rectifier diode bridge and a filter circuit to supply power to the load, a resonance reactor is provided on an output side of the transformer, a resonant switch circuit including a parallel circuit of a diode and a semiconductor switch and a resonant capacitor is connected in parallel to the rectifier diode bridge and a snubber circuit including a snubber capacitor, a snubber diode and a diode for discharge is connected to a serial resonant circuit including the resonance reactor and the resonant capacitor in the resonant switch circuit to absorb a surge voltage.
摘要翻译：在其中直流电源和变压器通过功率转换电路连接的直流电源和变压器的次级绕组经由整流二极管桥和滤波电路连接到负载以向负载供电，谐振电抗器设置在变压器的输出侧，包括二极管和半导体开关的并联电路和谐振电容器的谐振开关电路并联连接到整流二极管桥和包括缓冲电容器的缓冲电路，缓冲二极管和用于放电的二极管连接到包括谐振电抗器和谐振开关电路中的谐振电容器的串联谐振电路以吸收浪涌电压。

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