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1. 发明授权

US07713412B2 Filter device 有权
标题翻译：过滤装置
公开(公告)号：US07713412B2
公开(公告)日：2010-05-11
申请号：US12118336
申请日：2008-05-09
申请人： Klaus Heilmann , Gerhard Breith , Igor Raiko , Roland Sander , Steffen Fritzsche
发明人： Klaus Heilmann , Gerhard Breith , Igor Raiko , Roland Sander , Steffen Fritzsche
IPC分类号： B01D63/02 , B01D61/24 , B01D61/00
CPC分类号： B01D46/0004 , A61M1/16 , B01D61/30 , B01D63/02 , B01D65/00 , B01D2265/05 , B01D2313/06 , B01D2313/21
摘要： A hollow fiber filter device for dialysis having a housing and an end cap is described. The end cap is attached to an axial end of the housing, and has a curved channel in fluid communication with a fluid port, a fluid chamber having a flow path defined by a plurality of curved members connected to an upper interior surface. The distance between circumferentially adjacent curved members may decrease in a radially outward flow direction.
摘要翻译：描述了一种用于透析的中空纤维过滤装置，其具有壳体和端盖。端盖附接到壳体的轴向端部，并且具有与流体端口流体连通的弯曲通道，流体室具有由连接到上部内表面的多个弯曲构件限定的流动路径。周向相邻的弯曲构件之间的距离可以在径向向外的流动方向上减小。

2. 发明申请

US20080230467A1 FILTER DEVICE 有权
标题翻译：过滤器
公开(公告)号：US20080230467A1
公开(公告)日：2008-09-25
申请号：US12118336
申请日：2008-05-09
申请人： Klaus HEILMANN , Gerhard Breith , Igor Raiko , Roland Sander , Steffen Fritzsche
发明人： Klaus HEILMANN , Gerhard Breith , Igor Raiko , Roland Sander , Steffen Fritzsche
IPC分类号： B01D61/14 , B01D63/02 , B01D69/08
CPC分类号： B01D46/0004 , A61M1/16 , B01D61/30 , B01D63/02 , B01D65/00 , B01D2265/05 , B01D2313/06 , B01D2313/21
摘要： A filter device for mass exchange between two media separated by a membrane providing a low-stress transfer of blood flow from the connection area of the filter device to the fibers of a hollow fiber bundle is disclosed. Relatively uniform utilization of the fibers is provided by a membrane in the form of a hollow fiber bundle whose fiber cavities form a first flow space, with at least one inflow or outflow chamber connected to the first flow space being provided for supplying a medium to the hollow fiber bundle or removing a medium from the hollow fiber bundle. The inflow or outflow chamber is adjacent to an essentially circular or semicircular channel which is designed to be open in the direction of the ends of the hollow fibers and is connected to an inlet or outlet of the filter device. The channel is arranged approximately centrally with the hollow fiber bundle and preferably has a cross-sectional area that decreases in the direction of flow, and also preferably has an outside diameter that is less than the diameter of the hollow fiber bundle.An end cap for a filter device is also provided which as an inflow or outflow chamber adjacent to an essentially circular or semicircular channel designed to be open in the direction of the ends of the hollow fibers of a hollow fiber bundle arranged in a filter device casing connectable to the end cap. The essentially circular or semicircular canal is connected to an inlet or outlet of the end cap, arranged approximately centrally with the hollow fiber bundle, has a cross-sectional area that decreases in the direction of flow, and has an outside diameter that is smaller than the inside diameter of the area of the end cap which holds the hollow fiber bundle.
摘要翻译：公开了一种用于通过膜分离的两个介质之间的质量交换的过滤装置，其提供了从过滤装置的连接区域到中空纤维束的纤维的血流的低应力转移。纤维的相对均匀的利用由中空纤维束形式的膜提供，其纤维腔形成第一流动空间，其中至少一个连接到第一流动空间的流入或流出室用于向中空纤维束或从中空纤维束除去介质。流入或流出室与基本上圆形或半圆形的通道相邻，该通道被设计为在中空纤维的端部的方向上开口，并连接到过滤装置的入口或出口。通道与中空纤维束大致中心配置，优选具有在流动方向上减小的横截面积，并且还优选具有小于中空纤维束直径的外径。还提供了一种用于过滤装置的端盖，其作为与设置成在布置在过滤器装置壳体中的中空纤维束的中空纤维的端部的方向上开口的基本上圆形或半圆形通道相邻的流入或流出室可连接到端盖。基本上圆形或半圆形的管道连接到端盖的入口或出口，其与中空纤维束大致中心地布置，具有在流动方向上减小的横截面面积，并且具有小于保持中空纤维束的端盖的区域的内径。

3. 发明授权

US06641731B1 Filter device 有权
标题翻译：过滤装置
公开(公告)号：US06641731B1
公开(公告)日：2003-11-04
申请号：US09464605
申请日：1999-12-15
申请人： Klaus Heilmann , Gerhard Breith , Igor Raiko , Roland Sander , Steffen Fritzsche
发明人： Klaus Heilmann , Gerhard Breith , Igor Raiko , Roland Sander , Steffen Fritzsche
IPC分类号： B01D6302
CPC分类号： B01D46/0004 , A61M1/16 , B01D61/30 , B01D63/02 , B01D65/00 , B01D2265/05 , B01D2313/06 , B01D2313/21
摘要： A filter device for mass exchange between two media separated by a membrane is disclosed. The device provides for low-stress transfer of blood flow from the connection area of the filter device to the fibers of a hollow fiber bundle. Relatively uniform utilization of the fibers is provided by a membrane in the form of a hollow fiber bundle whose fiber cavities form a first flow space. At least one inflow or outflow chamber is connected to the first flow space for supplying a medium to the hollow fiber bundle or removing a medium from the hollow fiber bundle. The inflow or outflow chamber is adjacent to an essentially circular or semicircular channel which is designed to be open in the direction of the ends of the hollow fibers and is connected to an inlet or outlet of the filter device. The channel is arranged approximately centrally with the hollow fiber bundle.
摘要翻译：公开了一种用于通过膜分离的两种介质之间的质量交换的过滤装置。该装置提供从过滤装置的连接区域到中空纤维束的纤维的低流量的血液流动。纤维的相对均匀的利用由中空纤维束形式的膜提供，其纤维腔形成第一流动空间。至少一个流入或流出室连接到第一流动空间，用于向中空纤维束供应介质或从中空纤维束中移除介质。流入或流出室与基本上圆形或半圆形的通道相邻，该通道被设计为在中空纤维的端部的方向上开口，并连接到过滤装置的入口或出口。通道与中空纤维束大致中心配置。

4. 发明授权

US06419825B1 Closure element 有权
标题翻译：封闭元素
公开(公告)号：US06419825B1
公开(公告)日：2002-07-16
申请号：US09441182
申请日：1999-11-15
申请人： Uwe Hahmann , Christian Sauerwald , Klaus Heilmann , Gerhard Breith , Steffen Fritzsche , Igor Raiko
发明人： Uwe Hahmann , Christian Sauerwald , Klaus Heilmann , Gerhard Breith , Steffen Fritzsche , Igor Raiko
IPC分类号： A61M3920
CPC分类号： A61M39/20 , A61M1/169 , B01D61/30 , B01D65/00 , B01D65/022
摘要： A closure element for sterile closure of connections, in particular connections of filter modules for dialysis, hemofiltration or ultrafiltration is described. A closure element with a simple design that provides a reliable seal is formed by having the closure element include a wall with an automatically closing slit-shaped indentation which when closed creates a germ-proof seal. The sealing element is used for sterile closure of connections of medical items, as well as for the medical items themselves.
摘要翻译：描述了用于无菌封闭连接的闭合元件，特别是用于透析，血液滤过或超滤的过滤器模块的连接。具有提供可靠密封的简单设计的封闭元件通过具有封闭元件包括具有自动闭合的狭缝形凹陷的壁而形成，其在闭合时形成防菌密封。密封元件用于无菌封闭医疗用品的连接以及医疗用品本身。

5. 发明授权

US06858137B2 Filter module having a closure element 有权
标题翻译：过滤器模块具有闭合元件
公开(公告)号：US06858137B2
公开(公告)日：2005-02-22
申请号：US10052768
申请日：2002-01-18
申请人： Uwe Hahmann , Christian Sauerwald , Klaus Heilmann , Gerhard Breith , Steffen Fritzsche
发明人： Uwe Hahmann , Christian Sauerwald , Klaus Heilmann , Gerhard Breith , Steffen Fritzsche
IPC分类号： A61M1/14 , A61M1/16 , A61M39/20 , B01D61/30 , B01D65/00 , B01D65/02
CPC分类号： A61M39/20 , A61M1/169 , B01D61/30 , B01D65/00 , B01D65/022
摘要： A closure element for sterile closure of connections, in particular connections of filter modules for dialysis, hemofiltration or ultrafiltration is described. A closure element with a simple design that provides a reliable seal is formed by having the closure element include a wall with an automatically closing slit-shaped indentation which when closed creates a germ-proof seal. The sealing element is used for sterile closure of connections of medical items, as well as for the medical items themselves.
摘要翻译：描述了用于无菌封闭连接的闭合元件，特别是用于透析，血液滤过或超滤的过滤器模块的连接。具有提供可靠密封的简单设计的封闭元件通过具有封闭元件包括具有自动闭合的狭缝形凹陷的壁而形成，其在闭合时形成防菌密封。密封元件用于无菌封闭医疗用品的连接以及医疗用品本身。

6. 发明授权

US08182686B2 Hollow fiber membrane separation device 有权
标题翻译：中空纤维膜分离装置
公开(公告)号：US08182686B2
公开(公告)日：2012-05-22
申请号：US11991913
申请日：2006-06-08
申请人： Friedrich Witthaus , Gerhard Breith
发明人： Friedrich Witthaus , Gerhard Breith
IPC分类号： B01D63/00 , C02F1/44
CPC分类号： B01D63/02 , B01D2313/20
摘要： A hollow fiber membrane separation device with two flow spaces, of which a first space is formed by the capillary tube passages of a hollow-fiber bundle cast at its ends into a sealing compound, and a second space is formed by a housing enclosing the fiber bundle. The first space is sealed off by caps, placed on the sealing compounds, with seals running over the peripheral areas of the sealing compounds. The housing, into which the hollow-fiber bundle is drawn, at each end of its casing has tooth-like or pinnacle-like projections formed by axial notches or indentations running out freely. The tooth-like or pinnacle-like projections have extensions extending from the sides of the projections and extending to the adjacent tooth-like or pinnacle-like projection.
摘要翻译：一种具有两个流动空间的中空纤维膜分离装置，其第一空间由其端部处于密封化合物的中空纤维束的毛细管通道形成，并且第二空间由围绕纤维的壳体形成束。第一个空间由盖子封闭，放置在密封化合物上，密封件运行在密封化合物的周边区域上。中空纤维束被拉出的壳体在其壳体的每个端部处具有由轴向凹口或凹陷自由流出形成的齿状或巅峰状突起。牙形或巅峰状突起具有从突出部的侧面延伸并延伸到相邻的齿状或尖顶状突出部的延伸部。

7. 发明申请

US20090301961A1 Hollow Fiber Membrane Separation Device 有权
标题翻译：中空纤维膜分离装置
公开(公告)号：US20090301961A1
公开(公告)日：2009-12-10
申请号：US11991913
申请日：2006-06-08
申请人： Friedrich Witthaus , Gerhard Breith
发明人： Friedrich Witthaus , Gerhard Breith
IPC分类号： B01D29/13
CPC分类号： B01D63/02 , B01D2313/20
摘要： The present invention refers to a hollow fiber membrane separation device with two flow spaces, of which a first space is formed by the capillary tube passages of a hollow-fiber bundle cast at its ends into a sealing compound, and a second space is formed by a housing enclosing the fiber bundle, wherein the first space is sealed off by caps, placed on the sealing compounds, with seals running over the peripheral areas of the sealing compounds, and wherein the housing, into which the hollow-fiber bundle is drawn, at each end of its casing has tooth-like or pinnacle-like projections formed by axial notches or indentations running out freely. According to the invention, the housing has, between the tooth-like or pinnacle-like projections, extensions extending from said projections and extending to the adjacent tooth-like or pinnacle-like projection.
摘要翻译：本发明涉及一种具有两个流动空间的中空纤维膜分离装置，其中，第一空间由其末端浇注成密封化合物的中空纤维束的毛细管通道形成，第二空间由围绕所述纤维束的壳体，其中所述第一空间由盖子封闭，放置在所述密封化合物上，密封件在所述密封化合物的周边区域上延伸，并且其中所述中空纤维束被拉出的所述壳体，在其壳体的每一端具有由轴向凹口或凹陷自由流出形成的齿状或巅峰状突起。根据本发明，壳体在齿状或巅峰状突起之间具有从所述凸起延伸并延伸到相邻的齿状或顶点状突出部的延伸部。

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