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    • 2. 发明授权
    • Process for synthesis of N,N-disubstituted hydrazone
    • 合成N,N-二取代腙的方法
    • US4990625A
    • 1991-02-05
    • US445930
    • 1989-12-05
    • Tetsuo AritaMinoru MabuchiShoji UmeharaKiyoshi Sakai
    • Tetsuo AritaMinoru MabuchiShoji UmeharaKiyoshi Sakai
    • C07C249/16C07D209/86C09B26/02G03G5/06
    • C07C249/16C07D209/86G03G5/0616
    • A process for synthesizing an N,N-disubstituted hydrazone comprises carrying out nitrozation by adding an aqueous solution of sodium nitrite to a solution having one part by weight of an N,N-disubstituted amine dissolved in 3 to 30 parts by weight of an organic acid, then reducing the nitrozated product to an N,N-disubstituted hydrazine by adding a reducing agent to the mixture containing the nitrozated product, and thereafter adding to the mixture containing the N,N-disubstituted hydrazine a carbonyl compound of the formula: ##STR1## wherein A represents an aromatic hydrocarbon group or an aromatic heterocyclic group which may have a substituent, B represents a hydrogen atom, an alkyl group, an aryl group or an aromatic heterocyclic group, which may have a substituent, thereby performing condensation of the N,N-disubstituted hydrazine with the carbonyl compound.
    • 合成N,N-二取代腙的方法包括通过将亚硝酸钠水溶液加入到溶解有3重量份的N,N-二取代胺的溶液中进行硝化,所述N,N-二取代胺溶解在3-30重量份的有机 然后通过向含有硝基化产物的混合物中加入还原剂将硝化产物还原成N,N-二取代的肼,然后向含有N,N-二取代肼的混合物中加入下式的羰基化合物: 其中A表示可以具有取代基的芳香族烃基或芳香族杂环基,B表示可以具有取代基的氢原子,烷基,芳基或芳香族杂环基,由此进行 N,N-二取代肼与羰基化合物。