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1. 发明授权

US10253309B2 Apparatus for separating fine particles using magnetophoresis, and method for separating fine particles using same 有权
公开(公告)号：US10253309B2
公开(公告)日：2019-04-09
申请号：US13821477
申请日：2011-08-19
申请人： Ki Ho Han , Hwan Yong Lee , Song I Han , Seon Young Kim , In Hak Choi
发明人： Ki Ho Han , Hwan Yong Lee , Song I Han , Seon Young Kim , In Hak Choi
IPC分类号： C12N13/00 , C07H1/08 , B03C1/033 , B03C1/32 , G01N27/74 , G01N15/10
摘要： The present invention relates to an apparatus for separating fine particles using magnetophoresis, and to a method for separating fine particles using same, and particularly, to an apparatus for separating fine particles using magnetophoresis, which includes a fine, patterned magnetic structure capable of quickly and efficiently separating even particles that are weakly magnetized and coupled to fine particles, and to a method for separating fine particles using same.

2. 发明申请

US20130189755A1 APPARATUS FOR SEPARATING FINE PARTICLES USING MAGNETOPHORESIS, AND METHOD FOR SEPARATING FINE PARTICLES USING SAME 审中-公开
标题翻译：使用磁分离分离精细颗粒的装置以及使用其分离精细颗粒的方法
公开(公告)号：US20130189755A1
公开(公告)日：2013-07-25
申请号：US13821477
申请日：2011-08-19
申请人： Ki Ho Han , Hwan Yong Lee , Song l Han , Seon Young Kim , In Hak Choi
发明人： Ki Ho Han , Hwan Yong Lee , Song l Han , Seon Young Kim , In Hak Choi
IPC分类号： C12N13/00 , C07H1/08
CPC分类号： C12N13/00 , B03C1/0335 , B03C1/32 , B03C2201/18 , B03C2201/26 , C07H1/08 , G01N15/1056 , G01N27/745
摘要： The present invention relates to an apparatus for separating fine particles using magnetophoresis, and to a method for separating fine particles using same, and particularly, to an apparatus for separating fine particles using magnetophoresis, which includes a fine, patterned magnetic structure capable of quickly and efficiently separating even particles that are weakly magnetized and coupled to fine particles, and to a method for separating fine particles using same.
摘要翻译：本发明涉及使用磁电泳分离细颗粒的装置，以及使用其分离细颗粒的方法，特别涉及一种使用磁电泳分离细颗粒的装置，其包括精细的图案化磁结构，其能够快速和有效地分离微弱磁化并耦合到细颗粒的颗粒，以及使用其分离细颗粒的方法。

3. 发明授权

US09075066B2 CST1, DCC1, IFITM1 or MELK as markers for diagnosing stomach cancer 有权
标题翻译： CST1，DCC1，IFITM1或MELK作为诊断胃癌的标记物
公开(公告)号：US09075066B2
公开(公告)日：2015-07-07
申请号：US12679879
申请日：2009-04-21
申请人： Hee Gu Lee , Eun Young Song , Min Ah Kang , Jong Tae Kim , Jae Wha Kim , Young Il Yeom , Seon Young Kim , Kyung Chan Park
发明人： Hee Gu Lee , Eun Young Song , Min Ah Kang , Jong Tae Kim , Jae Wha Kim , Young Il Yeom , Seon Young Kim , Kyung Chan Park
IPC分类号： G01N33/53 , G01N33/574 , C12Q1/68
CPC分类号： G01N33/57446 , C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , G01N2500/04
摘要： The present invention relates to a biomarker for gastric cancer, CST1 (cysteine proteinase inhibitor, type 2 family), DCC1 (Defective in sister chromatid cohesion homolog 1), IFITM1 (interferon induced transmembrane protein 1) or MELK (maternal embryonic leucine zipper kinase). More particularly, the present invention relates to a diagnostic composition for gastric cancer comprising an agent measuring the expression level of CST1, DCC1, IFITM1 or MELK, a kit comprising the composition, a method for detecting the marker, and a method for screening a therapeutic agent for gastric cancer using the marker.
摘要翻译：本发明涉及胃癌生物标志物，CST1（半胱氨酸蛋白酶抑制剂，2型家族），DCC1（姐妹染色单体内聚同系物1缺陷），IFITM1（干扰素诱导的跨膜蛋白1）或MELK（母体白蛋白亮氨酸拉链激酶）。更具体地，本发明涉及用于胃癌的诊断组合物，其包含测量CST1，DCC1，IFITM1或MELK的表达水平的试剂，包含该组合物的试剂盒，用于检测标记物的方法和用于筛选治疗使用标记的胃癌药物。

4. 发明申请

US20130190200A1 SNP FOR PREDICTING THE SENSITIVITY TO ANTICANCER TARGETED THERAPEUTIC FORMULATION 审中-公开
标题翻译：用于预测抗精神病药物治疗药物灵敏度的SNP
公开(公告)号：US20130190200A1
公开(公告)日：2013-07-25
申请号：US13704423
申请日：2010-12-08
申请人： Jin Cheon Kim , Yong Sung Kim , Seon Young Kim , Dong Hyung Cho
发明人： Jin Cheon Kim , Yong Sung Kim , Seon Young Kim , Dong Hyung Cho
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/156
摘要： The present invention relates to a single nucleotide polymorphism (SNP) for predicting the sensitivity to an anticancer targeted therapeutic formulation, a polynucleotide containing the same, and a method for predicting the sensitivity to an anticancer targeted therapeutic formulation. According to the present invention, it is possible to predict the sensitivity of each individual to a certain anticancer targeted therapeutic formulation, using a small amount of a sample taken from a patient and thus to select a most suitable targeted therapeutic formulation over the entire duration of treatment for the patient.
摘要翻译：本发明涉及用于预测对抗癌靶向治疗制剂的敏感性的单核苷酸多态性（SNP），含有该制剂的多核苷酸，以及预测对抗癌靶向治疗剂型的敏感性的方法。根据本发明，可以使用少量来自患者的样品来预测每个个体对某种抗癌靶向治疗剂型的敏感性，从而在整个持续时间内选择最合适的靶向治疗制剂治疗病人。

5. 发明授权

US06484515B2 Pulse tube refrigerator 失效
标题翻译：脉管冰箱
公开(公告)号：US06484515B2
公开(公告)日：2002-11-26
申请号：US09992863
申请日：2001-11-27
申请人： Seon Young Kim , Dong Kon Hwang
发明人： Seon Young Kim , Dong Kon Hwang
IPC分类号： F25B900
CPC分类号： F25B9/145 , F02G1/043 , F02G2243/50 , F04B35/045 , F25B9/14 , F25B2309/001 , F25B2309/1406 , F25B2309/1408 , F25B2309/1412 , F25B2309/1421 , F25B2309/1423
摘要： A pulse tube refrigerator is provided. A pulse tube is inserted into a regenerator such that the central axis of the pulse tube parallels the central axis of the regenerator and that a U-shaped working gas channel is formed by the pulse tube and the regenerator. It is possible to refrigerate more members by increasing the available area of a cold head formed in a cold heat exchanger. It is possible to reduce a restriction on the installing space of a refrigerating unit by reducing the length of the refrigerating unit. It is possible to reduce manufacturing cost by reducing the number of sealing members for the combination of a sealed cell.
摘要翻译：提供脉冲管式冰箱。将脉冲管插入再生器中，使得脉冲管的中心轴与再生器的中心轴平行，并且由脉冲管和再生器形成U形工作气体通道。通过增加在冷热交换器中形成的冷头的可用面积可以冷却更多的部件。通过减小制冷单元的长度，可以减少制冷机组的安装空间的限制。通过减少用于密封电池组合的密封构件的数量，可以降低制造成本。

6. 发明授权

US06209328B1 Oil-free compressor-integrated pulse tube refrigerator 失效
标题翻译：无油压缩机集成脉冲管冰箱
公开(公告)号：US06209328B1
公开(公告)日：2001-04-03
申请号：US09359315
申请日：1999-07-23
申请人： Seon Young Kim , Kee Yong Hong , Sung Tae Kim
发明人： Seon Young Kim , Kee Yong Hong , Sung Tae Kim
IPC分类号： F25B900
CPC分类号： F04B35/045 , F02G2243/52 , F25B9/145 , F25B2309/001 , F25B2309/003 , F25B2309/006 , F25B2309/1417 , F25B2309/1424
摘要： A compressor integrated pulse tube refrigerator of an oil free type is disclosed. The refrigerator includes a driving unit including a sealed casing having a cylinder disposed at an upper center portion of the same and a working gas filled therein, a linear motor installed in the interior of the sealed casing for generating a driving force, a driving shaft which is engaged to a rotor of the linear motor and linearly reciprocates, a piston connected with the driving shaft and inserted in the cylinder and reciprocating together with the driving shaft for thereby pumping a working gas, and a plurality of elastic guide support members provided in the interior of the sealed casing; and a refrigerating unit, for thereby implementing a stable reciprocating movement between a cylinder and a piston in a state that an outer surface of the piston does not contact with an inner surface of the cylinder.
摘要翻译：公开了一种无油型压缩机集成脉冲管制冷器。冰箱包括驱动单元，该驱动单元包括密封壳体，该密封壳体具有设置在其上部的中心部分处的气缸和填充在其中的工作气体;安装在密封壳体内部以产生驱动力的线性马达;驱动轴，与线性电动机的转子接合并直线往复运动，活塞与驱动轴连接并插入到气缸中并与驱动轴一起往复运动，从而泵送工作气体;以及多个弹性引导支撑构件，密封外壳内部; 以及制冷单元，从而在活塞的外表面不与气缸的内表面接触的状态下实现气缸和活塞之间的稳定的往复运动。

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