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1. 发明申请

US20100292282A1 SYNTHESIS AND CRYSTALLINE FORMS OF CB-1 ANTAGONIST/INVERSE AGONIST 审中-公开
标题翻译： CB-1 ANTAGONIST / INVERSE AGONIST的合成和结晶形式
公开(公告)号：US20100292282A1
公开(公告)日：2010-11-18
申请号：US12681797
申请日：2008-10-20
申请人： Kevin R. Campos , Cheng-Yi Chen , Jennifer R. Foley , Michael Hillier , Wendy S. Jen , Amude M. Kassim , Artis Klapars , Andrey V. Peresypkin , Thorsten Rosner , Cecile G. Savarin , Matthew Tudge , Narayan Variankaval , Vicky Vydra , Dalian Zhao
发明人： Kevin R. Campos , Cheng-Yi Chen , Jennifer R. Foley , Michael Hillier , Wendy S. Jen , Amude M. Kassim , Artis Klapars , Andrey V. Peresypkin , Thorsten Rosner , Cecile G. Savarin , Matthew Tudge , Narayan Variankaval , Vicky Vydra , Dalian Zhao
IPC分类号： A61K31/4245 , C07D413/10 , C07D271/113 , C07C255/53 , A61P3/04 , A61P3/10 , A61P25/28
CPC分类号： C07D271/113 , C07C255/53 , C07D413/10
摘要： The present invention relates to a process for producing crystalline 3-[(1S)-1-(1-{(S)-(4-chlorophenyl)[3-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)phenyl]methyl}azetidin-3-yl)-2-fluoro-2-methyl-propyl]-5-fluorobenzonitrile, and novel salts, solvates, hydrates and polymorphs thereof.
摘要翻译：本发明涉及3 - [（1S）-1-（1 - {（S） - （4-氯苯基）[3-（5-氧代-4,5-二氢-1,3， 4-二唑-2-基）苯基]甲基}氮杂环丁烷-3-基）-2-氟-2-甲基 - 丙基] -5-氟苄腈及其新的盐，溶剂合物，水合物和多晶型物。

2. 发明申请

US20100041893A1 FORMATION OF TETRA-SUBSTITUTED ENAMIDES AND STEREOSELECTIVE REDUCTION THEREOF 审中-公开
标题翻译：四唑替代方法的形成及其选择性减少
公开(公告)号：US20100041893A1
公开(公告)日：2010-02-18
申请号：US12603901
申请日：2009-10-22
申请人： KEVIN R. CAMPOS , Artis Klapars , J. Christopher McWilliams , C. Scott Shultz , Debra J. Wallace , Alex M. Chen , Lisa F. Frey , Andrey V. Peresypkin , Yaling Wang , Robert M. Wenslow , Cheng-Yi Chen
发明人： KEVIN R. CAMPOS , Artis Klapars , J. Christopher McWilliams , C. Scott Shultz , Debra J. Wallace , Alex M. Chen , Lisa F. Frey , Andrey V. Peresypkin , Yaling Wang , Robert M. Wenslow , Cheng-Yi Chen
IPC分类号： C07D211/72 , C07C233/00
CPC分类号： C07C231/18 , C07C253/14 , C07C309/73 , C07D213/64 , C07C255/56
摘要： The present invention is directed to a practical process for the preparation of an enamide (II) by palladium catalyzed coupling of a primary amide (IV) with a compound of structural formula (III), as shown below: As well as to crystalline forms of a compound produced by this process, in particular, an anhydrous crystal form, Form B, and crystalline solvates falling into three patterns, Type 1, Type 2, and Type 3, and crystalline intermediate compounds produced in the process. Still further, the present invention relates to the stereoselective reduction of the tetrasubstituted enamide (II) to the corresponding amide (I).
摘要翻译：本发明涉及通过主要酰胺（IV）与结构式（III）的化合物的钯催化偶联制备烯酰胺（II）的实际方法，如下所示：除了结晶形式通过该方法制备的化合物，特别是无水晶体形式B和分解成三种图案的晶体溶剂化物，类型1，类型2和类型3以及在该方法中产生的结晶中间体化合物。此外，本发明涉及四取代的酰胺（II）与相应的酰胺（I）的立体选择性还原。

3. 发明授权

US07629470B2 Formation of tetra-substituted enamides and stereoselective reduction thereof 失效
标题翻译：四取代烯酰胺的形成及其立体选择性还原
公开(公告)号：US07629470B2
公开(公告)日：2009-12-08
申请号：US11629005
申请日：2005-07-01
申请人： Kevin R. Campos , Artis Klapars , J. Christopher McWilliams , C. Scott Shultz , Debra J. Wallace , Alex M. Chen , Lisa F. Frey , Andrey V. Peresypkin , Yaling Wang , Robert M. Wenslow , Cheng-Yi Chen
发明人： Kevin R. Campos , Artis Klapars , J. Christopher McWilliams , C. Scott Shultz , Debra J. Wallace , Alex M. Chen , Lisa F. Frey , Andrey V. Peresypkin , Yaling Wang , Robert M. Wenslow , Cheng-Yi Chen
IPC分类号： C07D213/63
CPC分类号： C07C231/18 , C07C253/14 , C07C309/73 , C07D213/64 , C07C255/56
摘要： The present invention is directed to a practical process for the preparation of an enamide (II) by palladium catalyzed coupling of a primary amide (IV) with a compound of structural formula (III), as shown below: As well as to crystalline forms of a compound produced by this process, in particular, an anhydrous crystal form, Form B, and crystalline solvates falling into three patterns, Type 1, Type 2, and Type 3, and crystalline intermediate compounds produced in the process. Still further, the present invention relates to the stereoselective reduction of the tetrasubstituted enamide (II) to the corresponding amide (I).
摘要翻译：本发明涉及通过主要酰胺（IV）与结构式（III）的化合物的钯催化偶联制备烯酰胺（II）的实际方法，如下所示：除了结晶形式通过该方法制备的化合物，特别是无水晶体形式B和分解成三种图案的晶体溶剂化物，类型1，类型2和类型3以及在该方法中产生的结晶中间体化合物。此外，本发明涉及四取代的酰胺（II）与相应的酰胺（I）的立体选择性还原。

4. 发明申请

US20090018340A1 Formation of Tetra-Substituted Enamides and Stereoselective Reduction Thereof 失效
标题翻译：四取代酰胺的形成及其立体选择性还原
公开(公告)号：US20090018340A1
公开(公告)日：2009-01-15
申请号：US11629005
申请日：2005-07-01
申请人： Kevin R. Campos , Artis Klapars , J. Christopher McWilliams , C. Scott Shultz , Debra J. Wallace , Alex M. Chen , Lisa F. Frey , Andrey V. Peresypkin , Yaling Wang , Robert M. Wenslow , Cheng-Yi Chen
发明人： Kevin R. Campos , Artis Klapars , J. Christopher McWilliams , C. Scott Shultz , Debra J. Wallace , Alex M. Chen , Lisa F. Frey , Andrey V. Peresypkin , Yaling Wang , Robert M. Wenslow , Cheng-Yi Chen
IPC分类号： C07D213/64 , C07C255/50
CPC分类号： C07C231/18 , C07C253/14 , C07C309/73 , C07D213/64 , C07C255/56
摘要： The present invention is directed to a practical process for the preparation of an enamide (II) by palladium catalyzed coupling of a primary amide (IV) with a compound of structural formula (III), as shown below: As well as to crystalline forms of a compound produced by this process, in particular, an anhydrous crystal form, Form B, and crystalline solvates falling into three patterns, Type 1, Type 2, and Type 3, and crystalline intermediate compounds produced in the process. Still further, the present invention relates to the stereoselective reduction of the tetrasubstituted enamide (II) to the corresponding amide (I).
摘要翻译：本发明涉及通过主要酰胺（IV）与结构式（III）的化合物的钯催化偶联制备烯酰胺（II）的实际方法，如下所示：除了结晶形式通过该方法制备的化合物，特别是无水晶体形式B和分解成三种图案的晶体溶剂化物，类型1，类型2和类型3以及在该方法中产生的结晶中间体化合物。此外，本发明涉及四取代的酰胺（II）与相应的酰胺（I）的立体选择性还原。

5. 发明申请

US20110157677A1 ELECTROWETTING DISPLAY AND PIXEL ARRAY SUBSTRATE THEREOF AND ELECTROWETTING DISPLAY PIXEL STRUCTURE THEREOF 失效
标题翻译：电镀显示器和像素阵列基板及其电子显示器像素结构
公开(公告)号：US20110157677A1
公开(公告)日：2011-06-30
申请号：US12979327
申请日：2010-12-28
申请人： Cheng-Yi Chen , Chih-Yuan Wang
发明人： Cheng-Yi Chen , Chih-Yuan Wang
IPC分类号： G02B26/00
CPC分类号： G02B26/004
摘要： An electrowetting display, a pixel array substrate thereof, and an electrowetting display pixel structure thereof are provided. The electrowetting display pixel structure is disposed on a substrate. The electrowetting display pixel structure includes a pixel electrode, a hydrophobic insulating layer and a wall. The pixel electrode is covered by the hydrophobic insulating layer. The wall is disposed on the hydrophobic insulating layer. The wall has a first side surface, a second side surface and at least one opening penetrating the first side surface and the second side surface. The opening is used for fluid medium to flow therethrough.
摘要翻译：提供电润湿显示器，其像素阵列基板及其电润湿显示像素结构。电润湿显示像素结构设置在基板上。电润湿显示像素结构包括像素电极，疏水绝缘层和壁。像素电极被疏水性绝缘层覆盖。壁设置在疏水绝缘层上。该壁具有第一侧表面，第二侧表面和穿过第一侧表面和第二侧表面的至少一个开口。开口用于流体介质流过其中。

6. 发明授权

US07708407B2 Eye tracking compensated method and device thereof 有权
标题翻译：眼睛跟踪补偿方法及其装置
公开(公告)号：US07708407B2
公开(公告)日：2010-05-04
申请号：US11818414
申请日：2007-06-14
申请人： Fu-Chi Yang , Chia-Hang Lee , Cheng-Yi Chen , I-Lin Ho
发明人： Fu-Chi Yang , Chia-Hang Lee , Cheng-Yi Chen , I-Lin Ho
IPC分类号： A61B3/14 , G09G5/00
CPC分类号： G06T5/003 , G06T5/50 , G06T7/20 , G06T2207/10016 , G06T2207/20201 , G09G3/3611 , G09G2320/0261
摘要： Motion blur associated with hold-type display devices may be reduced by eye tracking compensation. Eye tracking compensation may depend on the magnitude and direction of a motion vector, which may be used to generate a human-vision image compensation signal. An original input image signal and the human-vision image compensation signal may be used to generate and output a compensated image signal. As a result, motion blur arising from eye tracking characteristics is reduced.
摘要翻译：与保持型显示设备相关的运动模糊可以通过眼睛跟踪补偿来减少。眼睛跟踪补偿可以取决于运动矢量的大小和方向，运动矢量可用于产生人类视觉图像补偿信号。可以使用原始输入图像信号和人像图像补偿信号来生成并输出补偿图像信号。结果，减少了由眼睛跟踪特性引起的运动模糊。

7. 发明申请

US20070148095A1 Fluorescent magnetic nanoparticles with specific targeting functions 审中-公开
标题翻译：具有特定靶向功能的荧光磁性纳米颗粒
公开(公告)号：US20070148095A1
公开(公告)日：2007-06-28
申请号：US11430894
申请日：2006-05-10
申请人： Ming-Yao Chen , Chi-Min Chau , Hsiang Huang , Cheng-Yi Chen , Pei-Shin Jiang , Chin-I Lin
发明人： Ming-Yao Chen , Chi-Min Chau , Hsiang Huang , Cheng-Yi Chen , Pei-Shin Jiang , Chin-I Lin
IPC分类号： A61K49/10 , C07K16/46
CPC分类号： A61K49/0002 , A61K41/00 , A61K49/0032 , A61K49/0052 , A61K49/0054 , A61K49/0093
摘要： Magnetic nanoparticles with fluorescent properties and specific targeting functions. The fluorescent magnetic nanoparticle includes a magnetic nanoparticle, a biocompatible polymer chemically modifying the magnetic nanoparticle, a fluorescent dye coupled to the biocompatible polymer, and a specific targeting agent coupled to the biocompatible polymer. The fluorescent and magnetic properties of the nanoparticles provide different types of signal sources and therefore, prompt imaging using different types of imaging techniques to reconfirm foci is feasible.
摘要翻译：具有荧光性质和特异性靶向功能的磁性纳米颗粒。荧光磁性纳米颗粒包括磁性纳米颗粒，化学修饰磁性纳米颗粒的生物相容性聚合物，与生物相容性聚合物偶联的荧光染料和与生物相容性聚合物偶联的特异性靶向剂。纳米颗粒的荧光和磁性能提供不同类型的信号源，因此，使用不同类型的成像技术进行即时成像，以重新确认病灶是可行的。

8. 发明授权

US06915668B2 Wearable electrode apparatus and manufacture thereof 有权
标题翻译：可穿戴电极装置及其制造
公开(公告)号：US06915668B2
公开(公告)日：2005-07-12
申请号：US10704620
申请日：2003-11-12
申请人： Hong-Hsu Huang , Cheng-Yi Chen , Chun-Jong Kuo
发明人： Hong-Hsu Huang , Cheng-Yi Chen , Chun-Jong Kuo
IPC分类号： A61N1/04 , D04B1/14 , D04B1/24 , D04B1/22
CPC分类号： A61N1/0484 , A61N1/0408 , A61N1/0452 , A61N1/0456 , A61N1/0492 , D04B1/14 , D04B1/24 , D10B2401/16
摘要： The invention provides a wearable electrode apparatus and manufacture thereof. The wearable electrode apparatus includes a garment and 2M terminals. The garment includes 2M electrically conductive portions. Each of the terminals is disposed on one of the 2M electrically conductive portions, respectively, for purpose of connection with an external apparatus. In particular, a semi-garment is first formed and cut out from a fabric according to a pattern of the garment. The electrically conductive portions are formed together with or after the formation of the semi-garment. Then, the semi-garment with the electrically conductive portions is formed into the garment.
摘要翻译：本发明提供一种耐磨电极装置及其制造方法。可佩戴电极装置包括衣服和2M个终端。该服装包括2M导电部分。为了与外部设备连接，每个端子分别设置在2M导电部分中的一个上。特别地，根据衣服的图案，首先形成半成衣并从织物切出。导电部分与半服装形成在一起或之后形成。然后，将具有导电部分的半衣形成为衣服。

9. 发明授权

US08830306B2 Image controllers and display devices 有权
标题翻译：图像控制器和显示设备
公开(公告)号：US08830306B2
公开(公告)日：2014-09-09
申请号：US12683249
申请日：2010-01-06
申请人： Cheng-Yi Chen , Pot-Sun Lin , Ying-Jen Chen , Chun-Jui Wang
发明人： Cheng-Yi Chen , Pot-Sun Lin , Ying-Jen Chen , Chun-Jui Wang
IPC分类号： H04N15/00 , G09G3/00 , G02B27/26 , H04N13/04
CPC分类号： G09G3/003 , G02B27/26 , H04N13/324 , H04N13/337
摘要： A representative display device includes a display module, a polarization controller and a compensator. Each pixel region of the display module has a first sub-pixel region, a second sub-pixel region and a third sub-pixel region respectively providing a first light, a second light and a third light of the same polarization. The polarization controller has control regions that control the polarization of the light passing therethrough. The compensator has first compensating regions, second compensating regions and third compensating regions corresponding to the first sub-pixel regions, the second sub-pixel regions and the third sub-pixel regions, respectively. The compensations of phase retardation of the first light, the second light and the third light generated by passing through the first compensating regions, the second compensating regions and the third compensating regions are different from one another.
摘要翻译：代表性的显示装置包括显示模块，偏振控制器和补偿器。显示模块的每个像素区域具有分别提供具有相同偏振的第一光，第二光和第三光的第一子像素区域，第二子像素区域和第三子像素区域。偏振控制器具有控制通过其中的光的偏振的控制区域。补偿器具有分别对应于第一子像素区域，第二子像素区域和第三子像素区域的第一补偿区域，第二补偿区域和第三补偿区域。通过第一补偿区域，第二补偿区域和第三补偿区域产生的第一光，第二光和第三光的相位延迟的补偿彼此不同。

10. 发明申请

US20130335413A1 SYSTEM AND METHOD FOR ESTIMATING CONSTRUCTION DURATION 审中-公开
标题翻译：用于估计施工期限的系统和方法
公开(公告)号：US20130335413A1
公开(公告)日：2013-12-19
申请号：US13495286
申请日：2012-06-13
申请人： Wei-Chih Wang , Cheng-Yi Chen , Shao-Wei Weng
发明人： Wei-Chih Wang , Cheng-Yi Chen , Shao-Wei Weng
IPC分类号： G06T17/00
CPC分类号： G06Q10/06
摘要： A system and method for estimating construction duration. The system includes a three-dimensional (3D) building information model (BIM) module, a duration estimation module, and a 4D BIM module. The 3D BIM module constructs a 3D BIM based on inputted modeling instructions and generates quantity information corresponding to the 3D BIM. The duration estimation module calculates duration information for construction work based on inputted construction condition information and the quantity information of the 3D BIM produced. The 4D BIM module constructs a 4D BIM based on the 3D BIM and the duration information. Thus, the present invention can automatically calculate the quantity of building materials, estimate the construction duration, establish a construction progress table, and demonstrate the construction progress of the 4D BIM in an animated way, replacing the traditional way of manually processing information for duration estimation.
摘要翻译：一种用于估计施工持续时间的系统和方法。该系统包括三维（3D）建筑信息模型（BIM）模块，持续时间估计模块和4D BIM模块。 3D BIM模块基于输入的建模指令构建3D BIM，并生成与3D BIM对应的数量信息。持续时间估计模块基于输入的构造条件信息和所生产的3D BIM的数量信息来计算施工作业的持续时间信息。 4D BIM模块基于3D BIM和持续时间信息构建4D BIM。因此，本发明可以自动计算建筑材料的数量，估计施工时间，建立施工进度表，并以动画方式展示4D BIM的施工进度，取代传统的手动处理信息的方式进行持续时间估计。

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