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    • 6. 发明申请
    • METHOD FOR PREPARING AMICARBAZONE
    • 制备AMICARBAZONE的方法
    • US20150336906A1
    • 2015-11-26
    • US14761594
    • 2014-01-22
    • KS LABORATORIES CO., LTD.
    • Keun Sik KIMYeon Tak CHOI
    • C07D249/12C07C269/04C07C271/08
    • A01N47/38C07C269/04C07C271/08C07C281/02C07D249/12
    • The present invention relates to a method for preparing amicarbazone by using amino-triazolinone, which is an intermediate compound, and relates to a method for preparing amicarbazone, comprising the steps of: obtaining hydrazine carboxylic acid represented by 5 chemical formula (V) by reacting acylhydrazide represented by chemical formula (II) and a carbamating agent represented by chemical formula (III) or (IV); reacting the obtained hydrazine carboxylic acid represented by chemical formula (V) and hydrazine hydrate in the presence of a base catalyst; and reacting the obtained compound represented by chemical formula (I) 10 and an alkyl isocyanate represented by chemical formula (IV) in the presence of a base catalyst. Amino-triazolinone and amicarbazone would be stably produced by the present invention without safety gear and safety facilities for the leakage of phosgene, which has been conventionally used as a reactant.
    • 本发明涉及通过使用作为中间体化合物的氨基 - 三唑啉酮制备氨基脲的方法,涉及一种制备氨基咔唑酮的方法,该方法包括以下步骤:通过使化学式(Ⅴ)表示的肼羧酸通过 由化学式(II)表示的酰基酰肼和由化学式(III)或(IV)表示的氨基甲酸酯化剂; 在碱催化剂存在下,使所得化学式(V)的肼羧酸与水合肼反应; 在碱催化剂的存在下,使由化学式(I)10表示的所得化合物与由化学式(Ⅳ)表示的异氰酸烷基酯反应。 氨基三唑啉酮和氨基咔唑酮可以通过本发明稳定地生产,没有安全装置和用于作为反应物常规使用的光气泄漏的安全设施。