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1. 发明授权

US06468230B2 Core wire with shapeable tip 失效
公开(公告)号：US06468230B2
公开(公告)日：2002-10-22
申请号：US10035706
申请日：2001-12-21
申请人： Ketan P. Muni , Sivette Lam , Juan T. Domingo , Gholam-Reza Zadno-Azizi
发明人： Ketan P. Muni , Sivette Lam , Juan T. Domingo , Gholam-Reza Zadno-Azizi
IPC分类号： A61B500
CPC分类号： C22F1/006 , A61M25/09 , A61M2025/09175 , A61M2025/1093
摘要： The present invention provides an improved core wire for use in a medical catheter. In one aspect, the invention provides a core wire with a shapeable tip and method of using the same. A core wire previously made superelastic is subject to additional processing to remove its superelasticity thereby allowing the material to be shapeable to aid in advancing the core wire through a blood vessel or other body cavities. In another aspect of the present invention, a method is provided for securing the core wire to the distal end of an elongated catheter tubular body. The tubular body is mechanically crimped onto the core wire to secure the core wire in place. This crimping method has been found to increase the strength of the bond between the core wire and the catheter tube so that greater pull force is required to break the core wire off from the catheter.

2. 发明授权

US06190332B1 Core wire with shapeable tip 失效
标题翻译：具有可塑尖端的芯线
公开(公告)号：US06190332B1
公开(公告)日：2001-02-20
申请号：US09026357
申请日：1998-02-19
申请人： Ketan P. Muni , Sivette Lam , Juan T. Domingo , Gholam-Reza Zadno-Azizi , Samuel Omaleki , Isaac J. Kim , Celso J. Bagaoisan
发明人： Ketan P. Muni , Sivette Lam , Juan T. Domingo , Gholam-Reza Zadno-Azizi , Samuel Omaleki , Isaac J. Kim , Celso J. Bagaoisan
IPC分类号： A61B500
CPC分类号： C22F1/006 , A61M25/09 , A61M2025/09175 , A61M2025/1093
摘要： The present invention provides an improved core wire for use in a medical catheter. In one aspect, the invention provides a core wire with a shapeable tip and method of manufacturing the same. A core wire previously made superelastic is subject to additional processing to remove its superelasticity thereby allowing the material to be shapeable to aid in advancing the core wire through a blood vessel or other body cavities. In another aspect of the present invention, a method is provided for securing the core wire to the distal end of an elongated catheter tubular body. The tubular body is mechanically crimped onto the core wire to secure the core wire in place. This crimping method has been found to increase the strength of the bond between the core wire and the catheter tube so that greater pull force is required to break the core wire off from the catheter.
摘要翻译：本发明提供一种用于医疗导管的改进的芯线。一方面，本发明提供一种具有可成形尖端的芯线及其制造方法。预先制成超弹性的芯线经受额外的处理以去除其超弹性，从而允许材料可成型以帮助将芯线推进通过血管或其它体腔。在本发明的另一方面，提供了一种用于将芯线固定到细长导管管体的远端的方法。将管状体机械地压接在芯线上以将芯线固定到位。已经发现这种卷曲方法增加了芯线和导管之间的结合强度，使得需要更大的拉力来将芯线从导管断开。

3. 发明授权

US06375629B1 Core wire with shapeable tip 有权
标题翻译：具有可塑尖端的芯线
公开(公告)号：US06375629B1
公开(公告)日：2002-04-23
申请号：US09690588
申请日：2000-10-17
申请人： Ketan P. Muni , Sivette Lam , Juan T. Domingo , Gholam-Reza Zadno-Azizi , Samuel Omaleki , Isaac J. Kim , Celso J. Bagaoisan
发明人： Ketan P. Muni , Sivette Lam , Juan T. Domingo , Gholam-Reza Zadno-Azizi , Samuel Omaleki , Isaac J. Kim , Celso J. Bagaoisan
IPC分类号： A61B500
CPC分类号： C22F1/006 , A61M25/09 , A61M2025/09175 , A61M2025/1093
摘要： The present invention provides an improved core wire for use in a medical catheter. In one aspect, the invention provides a core wire with a shapeable tip and method of manufacturing the same. A core wire previously made superelastic is subject to additional processing to remove its superelasticity thereby allowing the material to be shapeable to aid in advancing the core wire through a blood vessel or other body cavities. In another aspect of the present invention, a method is provided for securing the core wire to the distal end of an elongated catheter tubular body. The tubular body is mechanically crimped onto the core wire to secure the core wire in place. This crimping method has been found to increase the strength of the bond between the core wire and the catheter tube so that greater pull force is required to break the core wire off from the catheter.
摘要翻译：本发明提供一种用于医疗导管的改进的芯线。一方面，本发明提供一种具有可成形尖端的芯线及其制造方法。预先制成超弹性的芯线经受额外的处理以去除其超弹性，从而允许材料可成型以帮助将芯线推进通过血管或其它体腔。在本发明的另一方面，提供了一种用于将芯线固定到细长导管管体的远端的方法。将管状体机械地压接在芯线上以将芯线固定到位。已经发现这种卷曲方法增加了芯线和导管之间的结合强度，使得需要更大的拉力来将芯线从导管断开。

4. 发明授权

US06355016B1 Catheter core wire 有权
标题翻译：导管芯线
公开(公告)号：US06355016B1
公开(公告)日：2002-03-12
申请号：US09253971
申请日：1999-02-22
申请人： Celso J. Bagaoisan , Ketan P. Muni , Gholam-Reza Zadno-Azizi , Sivette Lam , Juan T. Domingo , Isaac J. Kim , Samuel L. Omaleki , Jefferey C. Bleam
发明人： Celso J. Bagaoisan , Ketan P. Muni , Gholam-Reza Zadno-Azizi , Sivette Lam , Juan T. Domingo , Isaac J. Kim , Samuel L. Omaleki , Jefferey C. Bleam
IPC分类号： A61M2900
CPC分类号： A61M25/104 , A61M25/09 , A61M25/09033 , A61M2025/09175 , A61M2025/1093 , C22F1/006
摘要： Disclosed herein is an improved core wire for use in a medical catheter. In one aspect, a tapering core wire is incorporated into the distal end of a catheter. The catheter has a tubular body. Both ends of an inflatable balloon are mounted to the tubular body. The core wire extends from the distal end of the tubular body. In one embodiment, substantially all of the taper of the core wire occurs in the extending portion of the core wire over a length of at least 15 mm but no more than 60 mm. In another aspect, a core wire with a shapeable tip and method of manufacturing the same are provided. A core wire previously made superelastic is subject to additional processing to remove its superelasticity thereby allowing the material to be shapeable to aid in advancing the core wire through a blood vessel or other body cavities. In another aspect of the present invention, a method is provided for securing the core wire to the distal end of an elongated catheter tubular body. The tubular body is mechanically crimped onto the core wire to secure the core wire in place. This crimping method has been found to increase the strength of the bond between the core wire and the catheter tube so that greater pull force is required to break the core wire off from the catheter.
摘要翻译：本文公开了一种用于医疗导管的改进的芯线。在一个方面，锥形芯线被并入导管的远端。导管具有管状体。可充气气囊的两端安装在管状体上。芯线从管状体的远端延伸。在一个实施例中，芯线的基本上所有的锥形在芯线的延伸部分中发生长度至少为15mm但不大于60mm。另一方面，提供了具有可成形尖端的芯线及其制造方法。预先制成超弹性的芯线经受额外的处理以去除其超弹性，从而允许材料可成型以帮助将芯线推进通过血管或其它体腔。在本发明的另一方面，提供了一种用于将芯线固定到细长导管管体的远端的方法。将管状体机械地压接在芯线上以将芯线固定到位。已经发现这种卷曲方法增加了芯线和导管之间的结合强度，使得需要更大的拉力来将芯线从导管断开。

5. 发明授权

US06554795B2 Balloon catheter and method of manufacture 失效
标题翻译：球囊导管及制造方法
公开(公告)号：US06554795B2
公开(公告)日：2003-04-29
申请号：US09026225
申请日：1998-02-19
申请人： Celso J. Bagaoisan , Ketan P. Muni , Hung V. Ha , Sivette Lam , Gholam-Reza Zadno-Azizi , Mukund R. Patel
发明人： Celso J. Bagaoisan , Ketan P. Muni , Hung V. Ha , Sivette Lam , Gholam-Reza Zadno-Azizi , Mukund R. Patel
IPC分类号： A61M2900
CPC分类号： A61M25/1029 , A61M25/0009 , A61M25/1034 , B29C55/04
摘要： Disclosed herein is a compliant catheter balloon with an improved elastic response and reduced longitudinal expansion, and a method of forming the same. The balloon comprises a SEBS block copolymer, which is longitudinally pre-stretched during the balloon manufacture process. In order to control the working length of a balloon on a catheter, at least one adhesive stop is provided on the catheter which prevents adhesive from wicking into the working length of the balloon. Preferably, a pair of thermoset tubings with an outer diameter size close to the size of the inner diameter of the balloon are inserted on the distal portion of the catheter. After the proper placement of the balloon, the adhesive is applied at the balloon's proximal and distal ends. As the adhesive wicks to the balloon, the thermoset tubings will eventually stop the adhesive to prevent further wicking of adhesive into the balloon's working length. In another aspect of the present invention, there is provided a method of manufacturing a balloon catheter to improve centering of the balloon on the catheter. After a balloon tubing is stretched, the stretched tubing is clamped to a fixture and stabilized at about 100° C. for 15 minutes. This stabilization step ensures that a balloon mounted on a catheter will inflate in a uniform manner.
摘要翻译：本文公开了一种具有改进的弹性响应和减小的纵向膨胀的柔顺导管气囊及其形成方法。气球包含SEBS嵌段共聚物，其在球囊制造过程中被纵向预拉伸。为了控制导管上的气球的工作长度，在导管上提供至少一个粘合阻挡件，其防止粘合剂吸入气球的工作长度。优选地，具有接近球囊内径尺寸的外径尺寸的一对热固管插入导管的远端部分。在适当放置气囊之后，将粘合剂施加在气囊的近端和远端。当粘合剂吸入气球时，热固性管将最终停止粘合剂，以防止粘合剂进一步吸入气囊的工作长度。在本发明的另一方面，提供一种制造球囊导管以改善球囊在导管上的对中的方法。在气囊管被拉伸之后，将拉伸的管道夹紧到夹具上并在约100℃下稳定15分钟。该稳定步骤确保安装在导管上的气囊将以均匀的方式充气。

6. 发明授权

US08747389B2 Systems for treating disorders of the ear, nose and throat 有权
标题翻译：用于治疗耳朵，鼻子和喉咙疾病的系统
公开(公告)号：US08747389B2
公开(公告)日：2014-06-10
申请号：US11789704
申请日：2007-04-24
申请人： Eric Goldfarb , John Y. Chang , William M. Facteau , Sivette Lam , Hung V. Ha , Isaac J. Kim , Ketan P. Muni
发明人： Eric Goldfarb , John Y. Chang , William M. Facteau , Sivette Lam , Hung V. Ha , Isaac J. Kim , Ketan P. Muni
IPC分类号： A61K9/22
CPC分类号： A61M29/02 , A61M25/0041 , A61M25/0045 , A61M25/0662 , A61M25/09 , A61M25/10 , A61M25/1002 , A61M2025/0046 , A61M2025/0681 , A61M2025/1086 , A61M2029/025 , A61M2210/0618 , A61M2210/0681 , A61M2230/005
摘要： Devices, systems and methods useable for dilating the ostia of paranasal sinuses and/or other passageways within the ear, nose or throat. A dilation catheter device and system is constructed in a manner that facilitates ease of use by the operator and, in at least some cases, allows the dilation procedure to be performed by a single operator. Additionally, the dilation catheter device and system may be useable in conjunction with an endoscope and/or a fluoroscope to provide for easy manipulation and positioning of the devices and real time visualization of the entire procedure or selected portions thereof. In some embodiments, an optional handle may be used to facilitate grasping or supporting a device of the present invention as well as another device (e.g., an endoscope) with a single hand.
摘要翻译：可用于扩张鼻窦口和/或耳，鼻或咽喉内其他通道的口腔的装置，系统和方法。膨胀导管装置和系统以促进操作者易于使用的方式构造，并且在至少一些情况下允许扩张程序由单个操作者执行。此外，扩张导管装置和系统可以与内窥镜和/或荧光镜结合使用，以提供装置的容易操作和定位以及整个程序或其选定部分的实时可视化。在一些实施例中，可以使用可选的手柄来便于用单手抓握或支撑本发明的装置以及另一装置（例如，内窥镜）。

7. 发明申请

US20080195041A1 Systems and methods for transnasal dilation of passageways in the ear, nose and throat 有权
标题翻译：鼻，鼻和喉部通道经鼻扩张的系统和方法
公开(公告)号：US20080195041A1
公开(公告)日：2008-08-14
申请号：US11789704
申请日：2007-04-24
申请人： Eric Goldfarb , John Y. Chang , William M. Facteau , Sivette Lam , Hung V. Ha , Isaac J. Kim , Ketan P. Muni
发明人： Eric Goldfarb , John Y. Chang , William M. Facteau , Sivette Lam , Hung V. Ha , Isaac J. Kim , Ketan P. Muni
IPC分类号： A61M29/02
CPC分类号： A61M29/02 , A61M25/0041 , A61M25/0045 , A61M25/0662 , A61M25/09 , A61M25/10 , A61M25/1002 , A61M2025/0046 , A61M2025/0681 , A61M2025/1086 , A61M2029/025 , A61M2210/0618 , A61M2210/0681 , A61M2230/005
摘要： Devices, systems and methods useable for dilating the ostia of paranasal sinuses and/or other passageways within the ear, nose or throat. A dilation catheter device and system is constructed in a manner that facilitates ease of use by the operator and, in at least some cases, allows the dilation procedure to be performed by a single operator. Additionally, the dilation catheter device and system may be useable in conjunction with an endoscope and/or a fluoroscope to provide for easy manipulation and positioning of the devices and real time visualization of the entire procedure or selected portions thereof. In some embodiments, an optional handle may be used to facilitate grasping or supporting a device of the present invention as well as another device (e.g., an endoscope) with a single hand.
摘要翻译：可用于扩张鼻窦口和/或耳，鼻或咽喉内其他通道的口腔的装置，系统和方法。膨胀导管装置和系统以促进操作者易于使用的方式构造，并且在至少一些情况下允许扩张程序由单个操作者执行。此外，扩张导管装置和系统可以与内窥镜和/或荧光镜结合使用，以提供装置的简单操作和定位以及整个程序或其选定部分的实时可视化。在一些实施例中，可以使用可选的手柄来便于用单手抓握或支撑本发明的装置以及另一装置（例如，内窥镜）。

8. 发明授权

US5868705A Pre-stretched catheter balloon 失效
标题翻译：预先拉伸的导管球囊
公开(公告)号：US5868705A
公开(公告)日：1999-02-09
申请号：US812140
申请日：1997-03-06
申请人： Celso J. Bagaoisan , Ketan P. Muni , Hung V. Ha , Sivette Lam , Gholan-Reza Zadno-Azizi
发明人： Celso J. Bagaoisan , Ketan P. Muni , Hung V. Ha , Sivette Lam , Gholan-Reza Zadno-Azizi
IPC分类号： A61B17/22 , A61F2/958 , A61M1/00 , A61M25/00 , A61M29/02 , B29C55/04 , A61M29/00
CPC分类号： B29C55/04 , A61B17/22 , A61L29/00 , A61M25/0009 , A61M25/0054 , A61M25/0075 , A61M25/09 , A61M25/09033 , A61M25/1011 , A61M25/1018 , A61M25/104 , A61B2017/22067 , A61B2017/22084 , A61B2217/005 , A61M2025/0018 , A61M2025/0081 , A61M2025/0183 , A61M2025/09008 , A61M2025/09175 , A61M2025/1015 , A61M2025/1031 , A61M2025/1052 , A61M2025/1079 , A61M2025/109 , A61M2025/1093 , A61M25/0026 , A61M25/0068 , A61M25/007 , A61M25/10 , A61M25/1027
摘要： Disclosed herein is a compliant catheter balloon with an improved elastic response and reduced longitudinal expansion, and a method of forming the same. The balloon comprises a SEBS block copolymer, which is longitudinally prestretched during the balloon manufacture process.
摘要翻译：本文公开了一种具有改进的弹性响应和减小的纵向膨胀的柔顺导管气囊及其形成方法。气球包含SEBS嵌段共聚物，其在球囊制造过程中被纵向预拉伸。

9. 发明授权

US09399121B2 Systems and methods for transnasal dilation of passageways in the ear, nose or throat 有权
标题翻译：鼻，鼻或喉部通道经鼻扩张的系统和方法
公开(公告)号：US09399121B2
公开(公告)日：2016-07-26
申请号：US12496226
申请日：2009-07-01
申请人： Eric Goldfarb , John Y. Chang , William M. Facteau , Sivette Lam , Hung V. Ha , Isaac J. Kim , Ketan P. Muni
发明人： Eric Goldfarb , John Y. Chang , William M. Facteau , Sivette Lam , Hung V. Ha , Isaac J. Kim , Ketan P. Muni
IPC分类号： A61M29/02 , A61M25/00 , A61M25/10
CPC分类号： A61B17/24 , A61B6/12 , A61B6/487 , A61B2017/246 , A61M25/0041 , A61M25/09 , A61M25/1002 , A61M29/02 , A61M2025/1079 , A61M2025/1086 , A61M2210/0618 , A61M2210/0681 , A61M2230/005
摘要： A dilation catheter device and system for dilating an opening in a paranasal sinus and/or other passageways within the ear, nose or throat is disclosed. A dilation catheter device and system is constructed in a manner that facilitates ease of use by the operator and, in at least some cases, allows the dilation procedure to be performed by a single operator. Additionally, the dilation catheter device and system may be useable in conjunction with an endoscope and/or a fluoroscope to provide for easy manipulation and positioning of the devices and real time visualization of the entire procedure or selected portions thereof. In some embodiments, shaft markers are disposed on a shaft of the dilation catheter and have a light color to contrast with a dark color of the dilation catheter shaft. The high contrast between the markers and catheter shaft allows for easy viewing of the markers in low light and operation conditions.
摘要翻译：公开了一种扩张导管装置和系统，用于扩张鼻窦和/或耳朵，鼻子或喉部内的其它通道中的开口。膨胀导管装置和系统以促进操作者易于使用的方式构造，并且在至少一些情况下允许扩张程序由单个操作者执行。此外，扩张导管装置和系统可以与内窥镜和/或荧光镜结合使用，以提供装置的容易操作和定位以及整个程序或其选定部分的实时可视化。在一些实施例中，轴标记设置在扩张导管的轴上并且具有与扩张导管轴的深色对比的浅色。标记和导管轴之间的高对比度允许在低光和操作条件下容易地观察标记。

10. 发明授权

US09095364B2 Device and method for dilating an airway stenosis 有权
标题翻译：扩张气道狭窄的装置和方法
公开(公告)号：US09095364B2
公开(公告)日：2015-08-04
申请号：US13551849
申请日：2012-07-18
申请人： Ketan P. Muni , Randy S. Chan , Sivette Lam , Shrirang V. Ranade
发明人： Ketan P. Muni , Randy S. Chan , Sivette Lam , Shrirang V. Ranade
IPC分类号： A61B5/05 , A61B17/24 , A61M16/04 , A61M29/02 , A61B6/12 , A61M16/00 , A61M16/08 , A61M25/00
CPC分类号： A61B17/24 , A61B6/12 , A61M16/0057 , A61M16/04 , A61M16/0438 , A61M16/044 , A61M16/0445 , A61M16/0463 , A61M16/0486 , A61M16/0488 , A61M16/0816 , A61M25/0026 , A61M25/007 , A61M29/02 , A61M2205/32 , A61M2205/6081
摘要： A medical device and a system and for dilating a stenotic airway of a patient are described. The medical device comprises a proximal end, a distal end, and a shaft system having an inflation lumen and a ventilation lumen the proximal end. The shaft system has a proximal shaft section and a distal shaft section. An inflatable balloon is attached to the distal shaft section in a position that is proximal to the distal end. The ventilating tip is distal to the balloon on the distal shaft section and has one or more radially facing openings. A method for treating a stenotic airway includes inserting the medical device into a patient's airway, and dilating and ventilating the airway.
摘要翻译：描述了医疗装置和系统，并且用于扩张患者的狭窄气道。医疗装置包括近端，远端以及具有充气腔和远端的通气腔的轴系。轴系具有近轴部分和远侧轴部分。可膨胀的气球在远端轴部分附近位于远端的位置。通气尖端在远侧轴部分上的球囊的远侧，并且具有一个或多个径向面对的开口。用于治疗狭窄性气道的方法包括将医疗装置插入患者的气道中，并使气道扩张和通气。

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