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    • 1. 发明授权
    • Pipette mechanism
    • 移液器机构
    • US4763535A
    • 1988-08-16
    • US004864
    • 1987-01-20
    • Kenneth RaininHaakon T. Magnussen, Jr.Roy P. Moeller
    • Kenneth RaininHaakon T. Magnussen, Jr.Roy P. Moeller
    • B01L3/02G01N1/14
    • B01L3/0224
    • A dashpot piston mounted in a closed chamber is coupled by an axially movable shaft to a pipette piston to regulate return movement of the pipette piston within a pipette cylinder to draw fluid into the cylinder. The dashpot shaft is movable within limits relative to the dashpot piston to accommodate a blow-out of residual fluid from the pipette by the shaft driving the pipette piston beyond a home position to blow residual fluid from the pipette cylinder. An air inlet port in the bottom of the chamber allows air to be drawn into the chamber with upward movement of the dashpot piston while a valve adjacent to the air inlet port opens in response to downward movement of the dashpot piston to exit air from the chamber. Control of the relative sizes of the air inlet port and valve outlet regulates the relative rates of upward and downward piston movement in the cylinder. The dashpot piston carries a movable plate of a variable capacitor transducer for monitoring the position of the pipette piston within the pipette cylinder.
    • 安装在封闭室中的缓冲器活塞通过可轴向移动的轴联接到移液管活塞,以调节移液管活塞在移液管气缸内的返回运动,以将流体吸入气缸。 缓冲器轴可相对于缓冲器活塞在极限内移动,以通过驱动移液管活塞的轴超过原始位置来容纳来自移液管的剩余流体的吹出,以吹送来自移液管的残余流体。 在室的底部的空气入口允许空气随着缓冲器活塞的向上运动而被吸入室中,同时与空气入口相邻的阀响应于缓冲器活塞向下移动以从腔室排出空气而打开 。 控制进气口和阀门出口的相对尺寸可调节气缸中上下活塞运动的相对速率。 缓冲器活塞承载可变电容换能器的可移动板,用于监测移液管活塞在移液管内的位置。
    • 7. 发明申请
    • STABILIZED ELECTRON MULTIPLIER ANODE
    • 稳定电子倍增阳极
    • US20130015767A1
    • 2013-01-17
    • US13184022
    • 2011-07-15
    • Urs SteinerRoy P. MoellerDavid Deford
    • Urs SteinerRoy P. MoellerDavid Deford
    • H01J43/30
    • H01J3/36H01J43/30H01J49/02H01J49/26
    • Methods and systems to compensate for distortions created by dynamic voltage applied to an electron multiplier used in mass spectrometry. An electron multiplier has a cathode end accepting ion flow, an opposite emitter end and an interior surface. The electron multiplier produces an electron output from ions colliding with the interior surface. A variable power supply has a voltage output coupled to the cathode end and the emitter end of the electron multiplier. The voltage output changes dynamically to adjust the electron output from the electron multiplier. An anode is located in proximity to the electron multiplier. An electrometer is coupled to the anode in proximity to the electron multiplier to measure the current generated by the electron output. A low pass filter circuit is coupled to the emitter end to the ground of the electrometer to attenuate emitter voltage changes. A bias circuit is coupled to the emitter end to stabilize emitter to anode voltage difference.
    • 用于补偿由施加到质谱仪中使用的电子倍增器的动态电压产生的失真的方法和系统。 电子倍增器具有阴极端接受离子流,相对的发射极端和内表面。 电子倍增器产生离子与内表面碰撞的电子输出。 可变电源具有耦合到电子倍增器的阴极端和发射极端的电压输出。 电压输出动态变化,以调整电子倍增器的电子输出。 阳极位于电子倍增器附近。 靠近电子倍增器的静电计耦合到阳极,以测量由电子输出产生的电流。 低通滤波器电路被耦合到发射极端到静电计的地面以衰减发射极电压变化。 偏置电路耦合到发射极端以稳定发射极与阳极的电压差。