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1. 发明授权

US08524918B2 Atropisomer of pyrrole derivative 有权
标题翻译：吡咯衍生物的倾向异构体
公开(公告)号：US08524918B2
公开(公告)日：2013-09-03
申请号：US12576091
申请日：2009-10-08
申请人： Kazumasa Aoki , Hiroyuki Tsuruoka , Noriyuki Hayashi , Juri Yoshida , Yusuke Asoh
发明人： Kazumasa Aoki , Hiroyuki Tsuruoka , Noriyuki Hayashi , Juri Yoshida , Yusuke Asoh
IPC分类号： C07D207/30 , A61K31/40
CPC分类号： C07D207/34
摘要： [Object] A prophylactic or therapeutic agent for a cardiovascular disease is provided.[Means for Resolution] An atropisomer of a compound represented by the following general formula (I): (wherein R1 is a C1-C3 alkyl group or a hydroxy-C1-C3 alkyl group; and R2 is a hydrogen atom or a C1-C3 alkoxy group).
摘要翻译：提供了一种用于心血管疾病的预防或治疗剂。 [解决方法]由以下通式（I）表示的化合物的阻转异构体：（其中R1是C1-C3烷基或羟基-C1-C3烷基; R2是氢原子或C1- C3烷氧基）。

2. 发明申请

US20100093826A1 ATROPISOMER OF PYRROLE DERIVATIVE 有权
标题翻译：光子衍生物的ATROPISOMER
公开(公告)号：US20100093826A1
公开(公告)日：2010-04-15
申请号：US12576091
申请日：2009-10-08
申请人： Kazumasa Aoki , Hiroyuki Tsuruoka , Noriyuki Hayashi , Juri Yoshida , Yusuke Asoh
发明人： Kazumasa Aoki , Hiroyuki Tsuruoka , Noriyuki Hayashi , Juri Yoshida , Yusuke Asoh
IPC分类号： A61K31/40 , C07D207/34 , A61P9/00 , A61P9/12 , A61P9/10
CPC分类号： C07D207/34
摘要： [Object] A prophylactic or therapeutic agent for a cardiovascular disease is provided.[Means for Resolution] An atropisomer of a compound represented by the following general formula (I): (wherein R1 is a C1-C3 alkyl group or a hydroxy-C1-C3 alkyl group; and R2 is a hydrogen atom or a C1-C3 alkoxy group).
摘要翻译：提供了一种用于心血管疾病的预防或治疗剂。 [解决方法]由以下通式（I）表示的化合物的阻转异构体：（其中R1是C1-C3烷基或羟基-C1-C3烷基; R2是氢原子或C1- C3烷氧基）。

3. 发明申请

US20110263544A1 1-Phenylpyrrole Derivatives 有权
标题翻译： 1-苯基吡咯衍生物
公开(公告)号：US20110263544A1
公开(公告)日：2011-10-27
申请号：US13122239
申请日：2009-10-07
申请人： John Nuss , Matthew Williams , Raju Mohan , Richard Martin , Tie-Lin Wang , Hiroyuki Tsuruoka , Kazumasa Aoki , Masatoshi Honzumi , Yusuke Asoh , Keiji Saito , Tsuyoshi Homma
发明人： John Nuss , Matthew Williams , Raju Mohan , Richard Martin , Tie-Lin Wang , Hiroyuki Tsuruoka , Kazumasa Aoki , Masatoshi Honzumi , Yusuke Asoh , Keiji Saito , Tsuyoshi Homma
IPC分类号： A61K31/635 , A61K31/402 , A61P9/10 , C12N5/071 , A61P13/12 , A61P5/42 , A61P7/10 , C07D207/34 , A61P9/12
CPC分类号： C07D207/34
摘要： The present invention comprises a compound for the prevention and/or treatment of cardiovascular diseases, nephropathy, fibrosis, primary aldosteronism or edema. The compound is of the following general formula (I): wherein R1 represents a C1-C3 alkyl group; R2 represents a hydroxy-C1-C4 alkyl group and the like; R3 represents a halogeno group, a halogeno-C1-C3 alkyl group and the like; R4 represents a hydrogen atom, a halogeno group and the like, —R5 represents a sulfamoyl group or a C1-C3 alkylsulfonyl group; R6 represents a hydrogen atom, a halogeno group and the like] or an N-oxide, atropisomer of the foregoing, or pharmaceutically acceptable salt of the foregoing.
摘要翻译：本发明包括用于预防和/或治疗心血管疾病，肾病，纤维化，原发性醛固酮增多症或水肿的化合物。该化合物具有以下通式（I）：其中R 1表示C 1 -C 3烷基; R2表示羟基-C1-C4烷基等; R 3表示卤代基，卤代-C 1 -C 3烷基等; R4表示氢原子，卤代基等，-R5表示氨磺酰基或C1-C3烷基磺酰基; R6表示氢原子，卤代基等]或上述的N-氧化物，阻转异构体或上述的药学上可接受的盐。

4. 发明授权

US08642640B2 1-phenylpyrrole derivatives 有权
标题翻译： 1-苯基吡咯衍生物
公开(公告)号：US08642640B2
公开(公告)日：2014-02-04
申请号：US13122239
申请日：2009-10-07
申请人： John Nuss , Matthew Williams , Raju Mohan , Richard Martin , Tie-Lin Wang , Hiroyuki Tsuruoka , Kazumasa Aoki , Masatoshi Honzumi , Yusuke Asoh , Keiji Saito , Tsuyoshi Homma
发明人： John Nuss , Matthew Williams , Raju Mohan , Richard Martin , Tie-Lin Wang , Hiroyuki Tsuruoka , Kazumasa Aoki , Masatoshi Honzumi , Yusuke Asoh , Keiji Saito , Tsuyoshi Homma
IPC分类号： A61K31/40 , C07D207/08
CPC分类号： C07D207/34
摘要： The present invention comprises a compound for the prevention and/or treatment of cardiovascular diseases, nephropathy, fibrosis, primary aldosteronism or edema. The compound is of the following general formula (I): wherein R1 represents a C1-C3 alkyl group; R2 represents a hydroxy-C1-C4 alkyl group and the like; R3 represents a halogeno group, a halogeno-C1-C3 alkyl group and the like; R4 represents a hydrogen atom, a halogeno group and the like, —R5 represents a sulfamoyl group or a C1-C3 alkylsulfonyl group; R6 represents a hydrogen atom, a halogeno group and the like] or an N-oxide, atropisomer of the foregoing, or pharmaceutically acceptable salt of the foregoing.
摘要翻译：本发明包括用于预防和/或治疗心血管疾病，肾病，纤维化，原发性醛固酮增多症或水肿的化合物。该化合物具有以下通式（I）：其中R 1表示C 1 -C 3烷基; R2表示羟基-C1-C4烷基等; R 3表示卤代基，卤代-C 1 -C 3烷基等; R4表示氢原子，卤代基等，-R5表示氨磺酰基或C1-C3烷基磺酰基; R6表示氢原子，卤代基等]或上述的N-氧化物，阻转异构体或上述的药学上可接受的盐。

5. 发明申请

US20110263673A1 Atropisomers of (Hydroxyalkyl) Pyrrole Derivatives 有权
标题翻译：（羟烷基）吡咯衍生物的阻转异构体
公开(公告)号：US20110263673A1
公开(公告)日：2011-10-27
申请号：US13122147
申请日：2009-10-07
申请人： John Nuss , Matthew Williams , Raju Mohan , Richard Martin , Tie-Lin Wang , Kazumasa Aoki , Hiroyuki Tsuruoka , Noriyuki Hayashi , Tsuyoshi Homma
发明人： John Nuss , Matthew Williams , Raju Mohan , Richard Martin , Tie-Lin Wang , Kazumasa Aoki , Hiroyuki Tsuruoka , Noriyuki Hayashi , Tsuyoshi Homma
IPC分类号： A61K31/40 , C12N5/071 , A61P3/10 , A61P9/10 , C07D207/34 , A61P9/00
CPC分类号： C07D207/34
摘要： The present invention comprises a compound for the prevention and/or treatment of cardiovascular diseases. The compound is an atropisomer of a compound represented by the following general formula (I): wherein R1 represents a C1-C3 alkyl group; R2 represents a 2-hydroxy-C4-C6 alkyl group; R3 represents a halogeno group, a halogeno-C1-C3 alkyl group and the like; R4 represents a hydrogen atom, a halogeno group and the like; R5 represents a C1-C3 alkyl group; and R6 represents a hydrogen atom, a halogeno group and the like] or atropisomers thereof.
摘要翻译：本发明包括用于预防和/或治疗心血管疾病的化合物。该化合物是由以下通式（I）表示的化合物的阻转异构体：其中R1表示C1-C3烷基; R2表示2-羟基-C4-C6烷基; R 3表示卤代基，卤代-C 1 -C 3烷基等; R4代表氢原子，卤代基等; R5代表C1-C3烷基; R6表示氢原子，卤代基等]或它们的阻转异构体。

6. 发明授权

US08487117B2 Atropisomers of (hydroxyalkyl) pyrrole derivatives 有权
标题翻译：（羟烷基）吡咯衍生物的阻转异构体
公开(公告)号：US08487117B2
公开(公告)日：2013-07-16
申请号：US13122147
申请日：2009-10-07
申请人： John Nuss , Matthew Williams , Raju Mohan , Richard Martin , Tie-Lin Wang , Kazumasa Aoki , Hiroyuki Tsuruoka , Noriyuki Hayashi , Tsuyoshi Homma
发明人： John Nuss , Matthew Williams , Raju Mohan , Richard Martin , Tie-Lin Wang , Kazumasa Aoki , Hiroyuki Tsuruoka , Noriyuki Hayashi , Tsuyoshi Homma
IPC分类号： C07D207/30 , A61K31/40
CPC分类号： C07D207/34
摘要： The present invention comprises a compound for the prevention and/or treatment of cardiovascular diseases. The compound is an atropisomer of a compound represented by the following general formula (I): wherein R1 represents a C1-C3 alkyl group; R2 represents a 2-hydroxy-C4-C6 alkyl group; R3 represents a halogeno group, a halogeno-C1-C3 alkyl group and the like; R4 represents a hydrogen atom, a halogeno group and the like; R5 represents a C1-C3 alkyl group; and R6 represents a hydrogen atom, a halogeno group and the like] or atropisomers thereof.
摘要翻译：本发明包括用于预防和/或治疗心血管疾病的化合物。该化合物是由以下通式（I）表示的化合物的阻转异构体：其中R1表示C1-C3烷基; R2表示2-羟基-C4-C6烷基; R 3表示卤代基，卤代-C 1 -C 3烷基等; R4代表氢原子，卤代基等; R5代表C1-C3烷基; R6表示氢原子，卤代基等]或它们的阻转异构体。

7. 发明授权

US07891663B2 Overlapped conveyance detection apparatus for printing sheet 有权
标题翻译：用于打印纸的重叠传送检测装置
公开(公告)号：US07891663B2
公开(公告)日：2011-02-22
申请号：US12052851
申请日：2008-03-21
申请人： Hiroyuki Tsuruoka
发明人： Hiroyuki Tsuruoka
IPC分类号： B65H7/02
CPC分类号： B65H7/12 , B65H2511/512 , B65H2511/524 , B65H2515/82 , B65H2553/30 , B65H2553/52 , B65H2220/01 , B65H2220/03
摘要： In an apparatus which detects overlapped conveyance of a printing sheet using ultrasonic wave attenuation, when a printing sheet with an IC tag is conveyed, the position of the IC tag on the printing sheet is acquired. By reference to the acquired IC tag position, overlapped conveyance detection is performed at a position which is not under the influence of the IC tag.
摘要翻译：在使用超声波衰减来检测打印纸的重叠传送的装置中，当传送具有IC标签的打印纸时，获取IC标签在打印纸上的位置。通过参照获取的IC标签位置，在不受IC标签影响的位置进行重叠输送检测。

8. 发明申请

US20050193813A1 Liquid level sensor switch 有权
标题翻译：液位传感器开关
公开(公告)号：US20050193813A1
公开(公告)日：2005-09-08
申请号：US11073287
申请日：2005-03-04
申请人： Hiroyuki Tsuruoka , Sadayoshi Oshima , Yuich Auchi
发明人： Hiroyuki Tsuruoka , Sadayoshi Oshima , Yuich Auchi
IPC分类号： G01F23/60 , G01F23/52
CPC分类号： G01F23/703
摘要： A liquid level sensor-switch capable of effectively reducing variations in levels detected depending on directions in which it is inclined. The sensor-switch has a case, a guide rod formed therein, a float mounted on the guide rod with a clearance and being movable in the vertical direction along the guide rod in the case, an electrode plate attached to the bottom of the float and a pair of terminals disposed on both sides of the guide rod on the inside bottom of the case, wherein the float moves downward as the level of liquid lowers and it detects a specified low level by contacting the electrode plate with the paired terminals to make conductive a circuit formed between the terminals. It is featured by the fact that a pair of protrusions for restricting a biased movement of the float with respect to the guide rod are provided on both sides of the guide rod on the inside bottom of the case in a direction with a specified angle to a direction of arrangement of the paired terminals.
摘要翻译：一种液面传感器开关，其能够有效地减少根据倾斜方向检测的水平的变化。传感器开关具有壳体，形成在其中的导杆，浮子，其安装在引导杆上，具有间隙，并且可沿壳体中的导杆在垂直方向上移动，附接到浮子底部的电极板，一对端子，其设置在壳体的内底部的导杆的两侧，其中，当液面降低时，浮子向下移动，并且通过使电极板与成对端子接触来检测到指定的低电平，以使导电形成在端子之间的电路。其特征在于，用于限制浮子相对于导杆的偏置运动的一对突起在与壳体的指定角度相关联的方向上设置在壳体内底部的导杆的两侧配对终端的布置方向。

9. 发明申请

US20090085284A1 OVERLAPPED CONVEYANCE DETECTION APPARATUS FOR PRINTING SHEET 有权
标题翻译：用于印刷板的重叠输送检测装置
公开(公告)号：US20090085284A1
公开(公告)日：2009-04-02
申请号：US12052851
申请日：2008-03-21
申请人： Hiroyuki Tsuruoka
发明人： Hiroyuki Tsuruoka
IPC分类号： B65H7/02
CPC分类号： B65H7/12 , B65H2511/512 , B65H2511/524 , B65H2515/82 , B65H2553/30 , B65H2553/52 , B65H2220/01 , B65H2220/03
摘要： In an apparatus which detects overlapped conveyance of a printing sheet using ultrasonic wave attenuation, when a printing sheet with an IC tag is conveyed, the position of the IC tag on the printing sheet is acquired. By reference to the acquired IC tag position, overlapped conveyance detection is performed at a position which is not under the influence of the IC tag.
摘要翻译：在使用超声波衰减来检测打印纸的重叠传送的装置中，当传送具有IC标签的打印纸时，获取IC标签在打印纸上的位置。通过参照获取的IC标签位置，在不受IC标签影响的位置进行重叠输送检测。

10. 发明授权

US07077003B2 Liquid level sensor switch 有权
标题翻译：液位传感器开关
公开(公告)号：US07077003B2
公开(公告)日：2006-07-18
申请号：US11073287
申请日：2005-03-04
申请人： Hiroyuki Tsuruoka , Sadayoshi Oshima , Yuich Auchi
发明人： Hiroyuki Tsuruoka , Sadayoshi Oshima , Yuich Auchi
IPC分类号： G01F23/70
CPC分类号： G01F23/703
摘要： A liquid level sensor-switch capable of effectively reducing variations in levels detected depending on directions in which it is inclined. The sensor-switch has a case, a guide rod formed therein, a float mounted on the guide rod with a clearance and being movable in the vertical direction along the guide rod in the case, an electrode plate attached to the bottom of the float and a pair of terminals disposed on both sides of the guide rod on the inside bottom of the case, wherein the float moves downward as the level of liquid lowers and it detects a specified low level by contacting the electrode plate with the paired terminals to make conductive a circuit formed between the terminals. It is featured by the fact that a pair of protrusions for restricting a biased movement of the float with respect to the guide rod are provided on both sides of the guide rod on the inside bottom of the case in a direction with a specified angle to a direction of arrangement of the paired terminals.
摘要翻译：一种液面传感器开关，其能够有效地减少根据倾斜方向检测的水平的变化。传感器开关具有壳体，形成在其中的导杆，浮子，其安装在引导杆上，具有间隙，并且可沿壳体中的导杆在垂直方向上移动，附接到浮子底部的电极板，一对端子，其设置在壳体的内底部的导杆的两侧，其中，随着液面降低，浮子向下移动，并且通过使电极板与成对的端子接触来检测到指定的低电平，从而导电形成在端子之间的电路。其特征在于，用于限制浮子相对于导杆的偏置运动的一对突起在与壳体的指定角度相关联的方向上设置在壳体内底部的导杆的两侧配对终端的布置方向。

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