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1. 发明授权

US07465747B2 Fluorescent label compounds 有权
标题翻译：荧光标签化合物
公开(公告)号：US07465747B2
公开(公告)日：2008-12-16
申请号：US10506242
申请日：2003-03-10
申请人： Kazuko Matsumoto , Jingli Yuan , Guilan Wang , Mingqian Tan
发明人： Kazuko Matsumoto , Jingli Yuan , Guilan Wang , Mingqian Tan
IPC分类号： C07D401/02 , A61K31/44
CPC分类号： C07D213/36 , C07D401/14 , G01N33/533
摘要： It is intended to provide novel labeling reagents characterized by having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.), easily forming a complex together with a rare earth ion, the complex being stable in an aqueous solution, and having a sufficient fluorescence intensity and a long fluorescence life time regardless of buffer types; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence assay method using the above fluorescent label; etc. Namely, labeling reagents comprising a compound having a 2,2′:6′,2″-tripyridine skeleton or a 2,6-dipyrazolopyridine skeleton and having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.) and a group capable of forming a complex together with a rare earth ion; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence labeling method using the above complex as a label; and a fluorescence assay method using the above fluorescent label.
摘要翻译：旨在提供新颖的标记试剂，其特征在于具有能够与待标记的物质结合的基团（例如生物物质，生理活性物质等），容易与稀土离子一起形成络合物，该复合物在水溶液中稳定，并且具有足够的荧光强度和长的荧光寿命，而不管缓冲液类型如何; 由上述标记试剂与稀土离子组成的络合物; 含有上述复合物的荧光标记物; 使用上述荧光标记物的荧光检测方法; 即，包括具有2,2'：6'，2“ - 三吡啶骨架或2,6-二吡唑并吡啶骨架的化合物的标记试剂，并具有能够结合待标记的物质的基团（例如，生物物质，生理活性物质等）和能够与稀土离子一起形成络合物的基团; 由上述标记试剂与稀土离子组成的络合物; 含有上述复合物的荧光标记物; 使用上述复合物作为标签的荧光标记方法; 和使用上述荧光标记物的荧光测定方法。

2. 发明申请

US20050255465A1 Novel fluorescent label compounds 有权
标题翻译：新型荧光标记化合物
公开(公告)号：US20050255465A1
公开(公告)日：2005-11-17
申请号：US10506242
申请日：2003-03-10
申请人： Kazuko Matsumoto , Jingli Yuan , Guilan Wang , Mingqian Tan
发明人： Kazuko Matsumoto , Jingli Yuan , Guilan Wang , Mingqian Tan
IPC分类号： C07D213/36 , C07D213/38 , C07D401/14 , C07D409/14 , C07D491/14 , C07D498/22 , C07F5/00 , C12Q1/68 , G01N33/533
CPC分类号： C07D213/36 , C07D401/14 , G01N33/533
摘要： It is intended to provide novel labeling reagents characterized by having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.), easily forming a complex together with a rare earth ion, the complex being stable in an aqueous solution, and having a sufficient fluorescence intensity and a long fluorescence life time regardless of buffer types; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence assay method using the above fluorescent label; etc. Namely, labeling reagents comprising a compound having a 2,2′:6′,2″-tripyridine skeleton or a 2,6-dipyrazolopyridine skeleton and having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.) and a group capable of forming a complex together with a rare earth ion; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence labeling method using the above complex as a label; and a fluorescence assay method using the above fluorescent label.
摘要翻译：旨在提供新颖的标记试剂，其特征在于具有能够与待标记的物质结合的基团（例如生物物质，生理活性物质等），容易与稀土离子一起形成络合物，该复合物在水溶液中稳定，并且具有足够的荧光强度和长的荧光寿命，而不管缓冲液类型如何; 由上述标记试剂与稀土离子组成的络合物; 含有上述复合物的荧光标记物; 使用上述荧光标记物的荧光检测方法; 即，包括具有2,2'：6'，2“ - 三吡啶骨架或2,6-二吡唑并吡啶骨架的化合物的标记试剂，并具有能够结合待标记的物质的基团（例如，生物物质，生理活性物质等）和能够与稀土离子一起形成络合物的基团; 由上述标记试剂与稀土离子组成的络合物; 含有上述复合物的荧光标记物; 使用上述复合物作为标签的荧光标记方法; 和使用上述荧光标记物的荧光测定方法。

3. 发明申请

US20110062430A1 BLUE LIGHT EMITTING NANOMATERIALS AND SYNTHESIS THEREOF 审中-公开
标题翻译：蓝光发射纳米材料及其合成
公开(公告)号：US20110062430A1
公开(公告)日：2011-03-17
申请号：US12994273
申请日：2009-06-01
申请人： Franciscus Cornelis Jacobus Maria van Veggel , Mingqian Tan , Venkataramanan Mahalingam , Vasanthakumaran Sudarsan
发明人： Franciscus Cornelis Jacobus Maria van Veggel , Mingqian Tan , Venkataramanan Mahalingam , Vasanthakumaran Sudarsan
IPC分类号： H01L51/54 , H01L33/32 , C01B35/00 , C01B21/00 , C09K11/02 , C09K11/62 , C01F17/00 , B82Y40/00
CPC分类号： C09K11/62 , B82Y30/00 , C01B21/0632 , C01P2002/52 , C01P2002/72 , C01P2002/84 , C01P2004/04 , C01P2004/64 , H05B33/145
摘要： Methods for the production of a blue light emitting nanomaterial are provided comprising nitriding Group 13 metals to produce nitrided Group 13 metals and doping the nitrided Group 13 metals with a dopant, particularly an M2+ dopant, such as Mg2+ or Zn2+, to produce doped nanoparticles. Blue light emitting nanocomposites on other materials, such as SiO2 or TiO2, are also provided. Blue light emitting nanomaterials and nanocomposites also can be coupled to photonic crystals. Nanocrystal-based electroluminescence device are also disclosed.
摘要翻译：提供了制造蓝色发光纳米材料的方法，其包括氮化第13族金属以产生氮化的第13族金属，并用掺杂剂，特别是M2 +掺杂剂（例如Mg 2+或Zn 2+）掺杂氮化的第13族金属，以产生掺杂的纳米颗粒。还提供了在其它材料上的蓝光发射纳米复合材料，例如SiO 2或TiO 2。蓝光发射纳米材料和纳米复合材料也可以耦合到光子晶体。还公开了纳米晶体电致发光器件。

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