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1. 发明授权

US08637589B2 Silicone prepolymer solutions 有权
标题翻译：硅氧烷预聚物溶液
公开(公告)号：US08637589B2
公开(公告)日：2014-01-28
申请号：US12962575
申请日：2010-12-07
申请人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
发明人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
IPC分类号： G02B1/04
CPC分类号： C08F230/08 , C08K5/06 , C08L39/06 , G02B1/043 , C08L43/04
摘要： In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译：一方面，本发明涉及包含硅氧烷预聚物和溶剂的硅氧烷预聚物组合物。可以提供具有增加的平均硅含量的可溶性硅氧烷预聚物，从而获得所需的氧渗透性。通过选择和改变溶剂分子结构，可以提供亲水性和疏水性之间的所需平衡的溶剂，导致模制的聚合物膜和表现出极少的或不存在的眼睛刺激并且表现出高度透明的产品的制品。该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

2. 发明申请

US20110077322A1 Silicone Prepolymer Solutions 有权
标题翻译：硅酮预聚物解决方案
公开(公告)号：US20110077322A1
公开(公告)日：2011-03-31
申请号：US12962575
申请日：2010-12-07
申请人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
发明人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
IPC分类号： G02B1/04
CPC分类号： C08F230/08 , C08K5/06 , C08L39/06 , G02B1/043 , C08L43/04
摘要： In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译：一方面，本发明涉及包含硅氧烷预聚物和溶剂的硅氧烷预聚物组合物。可以提供具有增加的平均硅含量的可溶性硅氧烷预聚物，从而获得所需的氧渗透性。通过选择和改变溶剂分子结构，可以提供亲水性和疏水性之间的所需平衡的溶剂，导致模制的聚合物膜和表现出极少的或不存在的眼睛刺激并且表现出高度透明的产品的制品。该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

3. 发明申请

US20080081850A1 PROCESS FOR PRODUCING HYDROLYSIS-RESISTANT SILICONE COMPOUNDS 审中-公开
标题翻译：生产抗水解硅酮化合物的方法
公开(公告)号：US20080081850A1
公开(公告)日：2008-04-03
申请号：US11561525
申请日：2006-11-20
申请人： Kazuhiko Fujisawa , Masataka Nakamura , Mitsuru Yokota
发明人： Kazuhiko Fujisawa , Masataka Nakamura , Mitsuru Yokota
IPC分类号： G02B1/04
CPC分类号： C07F7/0876 , C07F7/0838
摘要： In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译：一方面，本发明涉及耐水解硅氧烷化合物。特别地，公开了空间位阻的耐水解硅氧烷化合物和改进的纯度耐水解硅氧烷化合物。还公开了制备耐水解硅氧烷化合物的方法; 所公开流程的产品; 包含所公开的化合物和所公开方法的产物的组合物和聚合物; 和眼科镜片，例如隐形眼镜，眼内透镜，人造角膜和眼镜镜片，包括所公开的组合物，公开的聚合物，公开的化合物和所公开的方法的产品。该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

4. 发明申请

US20120065348A1 SOLUBLE SILICONE PREPOLYMERS 有权
标题翻译：可溶性硅酮预处理剂
公开(公告)号：US20120065348A1
公开(公告)日：2012-03-15
申请号：US13300576
申请日：2011-11-19
申请人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
发明人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
IPC分类号： C08F30/08 , G02C7/04
CPC分类号： G02B1/043 , C07F7/0838 , C08F220/26 , C08F220/38 , C08F220/56 , C08F230/08
摘要： In one aspect, the invention relates to silicon-based prepolymers. The disclosed prepolymers exhibit satisfactory solubility in aqueous solutions or hydrophilic solutions and can overcome undesirable shrinkage, expansion, and related problems possessed by conventional silicone monomers and related conventional polymerization techniques by producing hydrogels from a crosslinkable prepolymer. Also disclosed are polymers and molded articles produced from the disclosed prepolymers, which attain a satisfactory oxygen permeability. Also disclosed are methods for producing the disclosed prepolymers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译：一方面，本发明涉及硅基预聚物。所公开的预聚物在水溶液或亲水溶液中表现出令人满意的溶解性，并且可以通过从可交联预聚物生产水凝胶来克服常规硅氧烷单体和相关常规聚合技术所具有的不期望的收缩，膨胀和相关问题。还公开了由公开的预聚物制备的聚合物和模塑制品，其获得令人满意的氧气渗透性。还公开了制备所公开的预聚物的方法。该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

5. 发明申请

US20080081894A1 HYDROLYSIS-RESISTANT SILICONE COMPOUNDS 有权
标题翻译：耐水解硅酮化合物
公开(公告)号：US20080081894A1
公开(公告)日：2008-04-03
申请号：US11561456
申请日：2006-11-20
申请人： Kazuhiko Fujisawa , Masataka Nakamura , Mitsuru Yokota , Douglas G. Vanderlaan
发明人： Kazuhiko Fujisawa , Masataka Nakamura , Mitsuru Yokota , Douglas G. Vanderlaan
IPC分类号： C08G77/04 , C07F7/04
CPC分类号： C07F7/0872 , C07F7/0838 , C07F7/0876 , C07F7/21 , C08F30/08 , C08G77/20 , G02B1/043
摘要： In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译：一方面，本发明涉及耐水解硅氧烷化合物。特别地，公开了空间位阻的耐水解硅氧烷化合物和改进的纯度耐水解硅氧烷化合物。还公开了制备耐水解硅氧烷化合物的方法; 所公开流程的产品; 包含所公开的化合物和所公开方法的产物的组合物和聚合物; 和眼科镜片，例如隐形眼镜，眼内透镜，人造角膜和眼镜镜片，包括所公开的组合物，公开的聚合物，公开的化合物和所公开的方法的产品。该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

6. 发明授权

US08053539B2 Siloxanyl materials for molded plastics 有权
标题翻译：用于模制塑料的硅氧烷材料
公开(公告)号：US08053539B2
公开(公告)日：2011-11-08
申请号：US11609677
申请日：2006-12-12
申请人： Masataka Nakamura , Kazuhiko Fujisawa , Mitsuru Yokota
发明人： Masataka Nakamura , Kazuhiko Fujisawa , Mitsuru Yokota
IPC分类号： C08F30/08 , C08G77/60 , C08G77/04
CPC分类号： C08G77/14 , C08F220/26 , C08F230/08 , C08G77/045
摘要： In one aspect, the invention relates to compositions comprising siloxanyl compounds comprising the structure: or residues thereof. Such compositions can be suitable for producing molded articles, can be excellent in transparency, hydrophilicity, and oxygen permeability, and can have a low modulus of elasticity and/or an excellent optical quality, so as to be suitable for ophthalmic lenses such as contact lenses and intraocular lenses. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译：在一个方面，本发明涉及包含结构或其残基的含有硅氧烷基化合物的组合物。这样的组合物可以适用于制造模塑制品，透明性，亲水性和透氧性优异，并且可以具有低弹性模量和/或优异的光学质量，以适用于眼镜片如隐形眼镜和眼内透镜。该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

7. 发明申请

US20090171026A1 SILICONE PREPOLYMER SOLUTIONS 有权
标题翻译：硅胶预处理溶液
公开(公告)号：US20090171026A1
公开(公告)日：2009-07-02
申请号：US12060536
申请日：2008-04-01
申请人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
发明人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
IPC分类号： C08L83/06 , C08G77/04
CPC分类号： C08F230/08 , C08K5/06 , C08L39/06 , G02B1/043 , C08L43/04
摘要： In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译：一方面，本发明涉及包含硅氧烷预聚物和溶剂的硅氧烷预聚物组合物。可以提供具有增加的平均硅含量的可溶性硅氧烷预聚物，从而获得所需的氧渗透性。通过选择和改变溶剂分子结构，可以提供亲水性和疏水性之间的所需平衡的溶剂，导致模制的聚合物膜和表现出极少的或不存在的眼睛刺激并且表现出高度透明的产品的制品。该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

8. 发明授权

US07329694B2 Ocular lens 有权
标题翻译：眼镜片
公开(公告)号：US07329694B2
公开(公告)日：2008-02-12
申请号：US10488089
申请日：2001-08-28
申请人： Masataka Nakamura , Kazuhiko Fujisawa , Naoki Shimoyama , Mitsuru Yokota
发明人： Masataka Nakamura , Kazuhiko Fujisawa , Naoki Shimoyama , Mitsuru Yokota
IPC分类号： G02B1/04
CPC分类号： C08F20/58 , G02B1/043 , C08L33/26 , C08L33/24 , C08L43/04
摘要： This invention provides an ophthalmic lens of high tensile elongation (i.e., that does not break easily). It is an ophthalmic lens comprising, as a polymerization component, monomers represented by formula (a) below: wherein, in formula (a), R1 is H or a methyl group; R2 is a group that is selected from alkyl groups with 1 to 8 carbon atoms, aralkyl groups with 7 to 12 carbon atoms and aryl groups with 6 to 10 carbon atoms; L1 is a substituent that is selected from ethylene groups, 1,2-propylene groups, 1,3-propylene groups and 1,4-butylene groups; and L2 is a substituent that is selected from methylene groups, ethylene groups, 1,2-propylene groups, 1,3-propylene groups and 1,4-butylene groups.
摘要翻译：本发明提供了一种具有高拉伸伸长率（即不容易破裂）的眼科镜片。作为聚合成分的眼用透镜，含有由下式（a）表示的单体：式（a）中，R 1为H或甲基; R 2是选自具有1至8个碳原子的烷基，具有7至12个碳原子的芳烷基和具有6至10个碳原子的芳基的基团; L 1是选自亚乙基，1,2-亚丙基，1,3-亚丙基和1,4-亚丁基的取代基; L 2是选自亚甲基，亚乙基，1,2-亚丙基，1,3-亚丙基和1,4-亚丁基的取代基。

9. 发明授权

US08399539B2 Soluble silicone prepolymers 有权
标题翻译：可溶性硅氧烷预聚物
公开(公告)号：US08399539B2
公开(公告)日：2013-03-19
申请号：US13300576
申请日：2011-11-19
申请人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
发明人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
IPC分类号： C08F290/06 , C08F283/12 , G02B1/04 , G02C7/00
CPC分类号： G02B1/043 , C07F7/0838 , C08F220/26 , C08F220/38 , C08F220/56 , C08F230/08
摘要： In one aspect, the invention relates to silicon-based prepolymers. The disclosed prepolymers exhibit satisfactory solubility in aqueous solutions or hydrophilic solutions and can overcome undesirable shrinkage, expansion, and related problems possessed by conventional silicone monomers and related conventional polymerization techniques by producing hydrogels from a crosslinkable prepolymer. Also disclosed are polymers and molded articles produced from the disclosed prepolymers, which attain a satisfactory oxygen permeability. Also disclosed are methods for producing the disclosed prepolymers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译：一方面，本发明涉及硅基预聚物。所公开的预聚物在水溶液或亲水溶液中表现出令人满意的溶解性，并且可以通过从可交联预聚物生产水凝胶来克服常规硅氧烷单体和相关常规聚合技术所具有的不期望的收缩，膨胀和相关问题。还公开了由公开的预聚物制备的聚合物和模塑制品，其获得令人满意的氧气渗透性。还公开了制备所公开的预聚物的方法。该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

10. 发明授权

US07897654B2 Silicone prepolymer solutions 有权
标题翻译：硅氧烷预聚物溶液
公开(公告)号：US07897654B2
公开(公告)日：2011-03-01
申请号：US12060536
申请日：2008-04-01
申请人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
发明人： Kazuhiko Fujisawa , Mitsuru Yokota , Masataka Nakamura
IPC分类号： G02B1/04
CPC分类号： C08F230/08 , C08K5/06 , C08L39/06 , G02B1/043 , C08L43/04
摘要： In one aspect, the invention relates to silicone prepolymer compositions comprising a silicone prepolymer and a solvent. A soluble silicone prepolymer can be provided having increased average silicon content, thereby attaining a desired oxygen permeability. A solvent can be provided with a desired balance between hydrophilicity and hydrophobicity by selection and modification of the solvent molecular structure, resulting in molded polymer films and articles that exhibit minimal or nonexistent eye irritation and exhibit highly transparent products. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译：一方面，本发明涉及包含硅氧烷预聚物和溶剂的硅氧烷预聚物组合物。可以提供具有增加的平均硅含量的可溶性硅氧烷预聚物，从而获得所需的氧渗透性。通过选择和改变溶剂分子结构，可以提供亲水性和疏水性之间的所需平衡的溶剂，导致模制的聚合物膜和表现出极少的或不存在的眼睛刺激并且表现出高度透明的产品的制品。该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

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