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1. 发明授权

US07862512B2 Blood vessel endothelium function evaluating apparatus provided with an electronic control device 有权
标题翻译：具有电子控制装置的血管内皮功能评价装置
公开(公告)号：US07862512B2
公开(公告)日：2011-01-04
申请号：US11507564
申请日：2006-08-22
申请人： Katsushi Iikubo , Hidehito Sasaki , Hidenori Suzuki , Hiromasa Tsukahara , Chikao Harada , Hitoshi Hirano , Hiroshi Masuda
发明人： Katsushi Iikubo , Hidehito Sasaki , Hidenori Suzuki , Hiromasa Tsukahara , Chikao Harada , Hitoshi Hirano , Hiroshi Masuda
IPC分类号： A61B8/00
CPC分类号： A61B8/14 , A61B5/02007 , A61B5/1075 , A61B8/4218
摘要： An apparatus for measuring a short-axis image of a blood vessel under a skin of a living being, the apparatus including an ultrasonic probe including an ultrasonic array which has a plurality of ultrasonic transducers arranged in one direction in an emission surface and which emits, from the emission surface, an ultrasonic beam toward the blood vessel, the ultrasonic probe additionally including a main frame which is adapted to be placed on the skin of the living being, an x-axis supporting device which is supported by the main frame and which supports the ultrasonic array such that the ultrasonic array is rotatable about an x axis parallel to the direction of arrangement of the ultrasonic transducers in the emission surface, and an x-axis control device which controls a posture of the ultrasonic array supported by the x-axis supporting device such that in a y-z plane, the emission surface of the ultrasonic array is parallel to the blood vessel.
摘要翻译：一种用于测量生物皮肤下的血管的短轴图像的装置，该装置包括超声波探头，该超声波探头包括超声波阵列，该超声波阵列具有沿发射表面沿一个方向排列的多个超声波换能器，所述超声波探头从所述发射面向所述血管进行超声波束，所述超声波探头还包括适于放置在所述生物体的皮肤上的主框架，由所述主框架支撑的x轴支撑装置，支撑超声波阵列使得超声波阵列能够绕平行于发射表面中的超声波换能器的方向的x轴旋转;以及x轴控制装置，其控制由x轴支撑的超声波阵列的姿势，轴向支撑装置，使得在yz平面中，超声波阵列的发射表面平行于血管。

2. 发明申请

US20070044336A1 Sensor holding apparatus 失效
标题翻译：传感器固定装置
公开(公告)号：US20070044336A1
公开(公告)日：2007-03-01
申请号：US11507545
申请日：2006-08-22
申请人： Katsushi IIkubo , Hidehito Sasaki , Hidenori Suzuki , Hiromasa Tsukahara , Chikao Harada , Hitoshi Hirano , Hiroshi Masuda
发明人： Katsushi IIkubo , Hidehito Sasaki , Hidenori Suzuki , Hiromasa Tsukahara , Chikao Harada , Hitoshi Hirano , Hiroshi Masuda
IPC分类号： G01B5/004
CPC分类号： G01B5/0004 , A61B5/021 , A61B5/1455 , A61B8/00 , A61B8/4218
摘要： An apparatus for holding a sensor such that the sensor touches an object at an arbitrary position in a three-dimensional space, the apparatus including a base member; a rotatable member which is rotatable relative to the base member about a vertical axis line; a first link device including a first stationary link, a first movable link, and two first pivotable links which are pivotably connected to the first stationary link and the first movable link, such that the first stationary link, the first movable link, and the two first pivotable links cooperate with each other to define a quadrilateral, wherein the first stationary link is fixed to the rotatable member such that the first movable link is movable in a plane containing the axis line; a second link device including two second pivotable links, and a second stationary link and a second movable link which are pivotably connected to the two second pivotable links, such that the two second pivotable links, the second stationary link, and the second movable link cooperate with each other to define a quadrilateral, wherein the second stationary link is fixed to the first movable link such that the second movable link is movable in the plane containing the axis line, and wherein the second movable link supports the sensor; a first biasing device which produces a thrust having a directional component resisting a load applied to the first movable link; and a second biasing device which produces a thrust having a directional component resisting a load applied to the second movable link.
摘要翻译：一种用于保持传感器的装置，使得传感器在三维空间中的任意位置处接触物体，该装置包括基座部件; 可旋转构件，其可相对于所述基座构件绕垂直轴线旋转; 第一连杆装置，包括第一固定连杆，第一可移动连杆和两个可枢转地连接到第一固定连杆和第一可动连杆的第一可枢转连杆，使得第一固定连杆，第一可动连杆和两个第一可枢转连杆彼此协作以限定四边形，其中第一固定连杆固定到可旋转构件，使得第一可移动连杆可在包含轴线的平面中移动; 包括两个第二可枢转连杆的第二连杆装置，以及可枢转地连接到两个第二可枢转连杆的第二固定连杆和第二可动连杆，使得两个第二可枢转连杆，第二固定连杆和第二可移动连杆配合彼此定义四边形，其中所述第二固定连杆固定到所述第一可动连杆，使得所述第二可移动连杆在包含所述轴线的平面中可移动，并且其中所述第二可移动连杆支撑所述传感器; 第一偏置装置，其产生具有抵抗施加到第一可动连杆的负载的方向分量的推力; 以及第二偏置装置，其产生具有抵抗施加到第二可动连杆的负载的方向分量的推力。

3. 发明授权

US07412776B2 Sensor holding apparatus 失效
标题翻译：传感器固定装置
公开(公告)号：US07412776B2
公开(公告)日：2008-08-19
申请号：US11507545
申请日：2006-08-22
申请人： Katsushi Iikubo , Hidehito Sasaki , Hidenori Suzuki , Hiromasa Tsukahara , Chikao Harada , Hitoshi Hirano , Hiroshi Masuda
发明人： Katsushi Iikubo , Hidehito Sasaki , Hidenori Suzuki , Hiromasa Tsukahara , Chikao Harada , Hitoshi Hirano , Hiroshi Masuda
IPC分类号： G01B5/004 , E04G3/00
CPC分类号： G01B5/0004 , A61B5/021 , A61B5/1455 , A61B8/00 , A61B8/4218
摘要： An apparatus for holding a sensor such that the sensor touches an object at an arbitrary position in a three-dimensional space, the apparatus including a base member; a rotatable member which is rotatable relative to the base member about a vertical axis line; a first link device including a first stationary link, a first movable link, and two first pivotable links which are pivotably connected to the first stationary link and the first movable link, such that the first stationary link, the first movable link, and the two first pivotable links cooperate with each other to define a quadrilateral, wherein the first stationary link is fixed to the rotatable member such that the first movable link is movable in a plane containing the axis line; a second link device including two second pivotable links, and a second stationary link and a second movable link which are pivotably connected to the two second pivotable links, such that the two second pivotable links, the second stationary link, and the second movable link cooperate with each other to define a quadrilateral, wherein the second stationary link is fixed to the first movable link such that the second movable link is movable in the plane containing the axis line, and wherein the second movable link supports the sensor; a first biasing device which produces a thrust having a directional component resisting a load applied to the first movable link; and a second biasing device which produces a thrust having a directional component resisting a load applied to the second movable link.
摘要翻译：一种用于保持传感器的装置，使得传感器在三维空间中的任意位置处接触物体，该装置包括基座部件; 可旋转构件，其可相对于所述基座构件绕垂直轴线旋转; 第一连杆装置，包括第一固定连杆，第一可移动连杆和两个可枢转地连接到第一固定连杆和第一可动连杆的第一可枢转连杆，使得第一固定连杆，第一可动连杆和两个第一可枢转连杆彼此协作以限定四边形，其中第一固定连杆固定到可旋转构件，使得第一可移动连杆可在包含轴线的平面中移动; 包括两个第二枢转连杆的第二连杆装置，以及可枢转地连接到两个第二可枢转连杆的第二固定连杆和第二可动连杆，使得两个第二可枢转连杆，第二固定连杆和第二可移动连杆配合彼此定义四边形，其中所述第二固定连杆固定到所述第一可动连杆，使得所述第二可移动连杆在包含所述轴线的平面中可移动，并且其中所述第二可移动连杆支撑所述传感器; 第一偏置装置，其产生具有抵抗施加到第一可动连杆的负载的方向分量的推力; 以及第二偏置装置，其产生具有抵抗施加到第二可动连杆的负载的方向分量的推力。

4. 发明申请

US20070060818A1 Blood-vessel-endothelium-function inspecting apparatus 审中-公开
标题翻译：血管内皮功能检查仪
公开(公告)号：US20070060818A1
公开(公告)日：2007-03-15
申请号：US11506847
申请日：2006-08-21
申请人： Katsushi Iikubo , Hidehito Sasaki , Hidenori Suzuki , Hiromasa Tsukahara , Chikao Harada , Hitoshi Hirano , Hiroshi Masuda
发明人： Katsushi Iikubo , Hidehito Sasaki , Hidenori Suzuki , Hiromasa Tsukahara , Chikao Harada , Hitoshi Hirano , Hiroshi Masuda
IPC分类号： A61B8/00
CPC分类号： A61B5/1075 , A61B5/02007 , A61B5/489 , A61B5/6824 , A61B8/06 , A61B8/0858 , A61B8/4218 , A61B8/4281
摘要： An apparatus for inspecting a function of an endothelium of a blood vessel of a living being, by stopping, using an inflatable cuff wound around a forearm of the living being, a flow of blood in a blood vessel of the forearm, subsequently ending the stopping of the flow of blood, and causing an ultrasonic probe placed on a skin of an upper arm of the living being to emit, from an emission surface thereof, an ultrasonic wave toward a blood vessel under the skin, the apparatus including an elbow-portion support member which supports an elbow portion of the living being; and a hand-dorsal-portion support member which supports a dorsal portion of a hand of the living being and which cooperates with the elbow-portion support member to keep, in a space, the inflatable cuff wound around the forearm of the living being.
摘要翻译：一种用于通过停止使用在前臂的前臂上缠绕的活动的前臂的可充气的袖带来检查生物的血管的内皮的功能的装置，其中，所述前臂的血管中的血液流，随后结束停止的血液流动，并且使得放置在生物体的上臂的皮肤上的超声波探头从其发射表面向皮肤下方的血管发射超声波，该装置包括肘部支撑构件，支撑生命的肘部; 以及手背部支撑构件，其支撑生物的手的背部并且与肘部支撑构件协作以在空间中保持缠绕在生物的前臂周围的可充气袖带。

5. 发明申请

US20070055152A1 Blood-vessel-image measuring apparatus 有权
标题翻译：血管图像测定装置
公开(公告)号：US20070055152A1
公开(公告)日：2007-03-08
申请号：US11507564
申请日：2006-08-22
申请人： Katsushi Ukubo , Hidehito Sasaki , Hidenori Suzuki , Hiromasa Tsukahara , Chikao Harada , Hitoshi Hirano , Hiroshi Masuda
发明人： Katsushi Ukubo , Hidehito Sasaki , Hidenori Suzuki , Hiromasa Tsukahara , Chikao Harada , Hitoshi Hirano , Hiroshi Masuda
IPC分类号： A61B8/00
CPC分类号： A61B8/14 , A61B5/02007 , A61B5/1075 , A61B8/4218
摘要： An apparatus for measuring a short-axis image of a blood vessel under a skin of a living being, the apparatus including an ultrasonic probe including an ultrasonic array which has a plurality of ultrasonic transducers arranged in one direction in an emission surface and which emits, from the emission surface, an ultrasonic beam toward the blood vessel, the ultrasonic probe additionally including a main frame which is adapted to be placed on the skin of the living being, an x-axis supporting device which is supported by the main frame and which supports the ultrasonic array such that the ultrasonic array is rotatable about an x axis parallel to the direction of arrangement of the ultrasonic transducers in the emission surface, and an x-axis control device which controls a posture of the ultrasonic array supported by the x-axis supporting device such that in a y-z plane, the emission surface of the ultrasonic array is parallel to the blood vessel.
摘要翻译：一种用于测量生物皮肤下的血管的短轴图像的装置，该装置包括超声波探头，该超声波探头包括超声波阵列，该超声波阵列具有沿发射表面沿一个方向排列的多个超声波换能器，所述超声波探头从所述发射面向所述血管进行超声波束，所述超声波探头还包括适于放置在所述生物体的皮肤上的主框架，由所述主框架支撑的x轴支撑装置，支撑超声波阵列使得超声波阵列能够绕平行于发射表面中的超声波换能器的方向的x轴旋转;以及x轴控制装置，其控制由x轴支撑的超声波阵列的姿势，轴向支撑装置，使得在yz平面中，超声波阵列的发射表面平行于血管。

6. 发明申请

US20120116227A1 ULTRASONIC BLOOD VESSEL INSPECTING APPARATUS 有权
标题翻译：超声波血管检查装置
公开(公告)号：US20120116227A1
公开(公告)日：2012-05-10
申请号：US13383866
申请日：2009-07-16
申请人： Hidenori Suzuki , Katsushi Iikubo , Chikao Harada , Hiroshi Masuda
发明人： Hidenori Suzuki , Katsushi Iikubo , Chikao Harada , Hiroshi Masuda
IPC分类号： A61B8/14
CPC分类号： A61B8/0858 , A61B5/02007 , A61B8/4218 , A61B8/461 , A61B8/5207 , A61B8/5223 , A61B8/54 , G01S7/52073 , G01S7/52074 , G01S7/52079 , G01S15/8925 , G01S15/8936
摘要： An ultrasonic blood vessel inspecting apparatus provided with a longitudinal cross sectional blood vessel image generating portion configured to generate a longitudinal cross sectional image of a blood vessel located below a skin of a live body, on the basis of reflected wave signals of an ultrasonic wave by using an ultrasonic probe placed on the skin of said live body, includes: an index value calculating portion configured to calculate an index value indicative of a degree of clarity of an image which represents an intima-media complex of said blood vessel and which exists within said longitudinal cross sectional image of the blood vessel.
摘要翻译：一种超声波血管检查装置，其具有纵剖视血管图像生成部，其构造成基于超声波的反射波信号，生成位于活体皮肤下方的血管的纵截面图像使用放置在所述活体的皮肤上的超声波探头，包括：指标值计算部，被配置为计算表示代表所述血管的内膜 - 媒体复合体的图像的清晰度的指标值，所述血管的纵向横截面图像。

7. 发明授权

US08939908B2 Ultrasonic blood vessel inspecting apparatus 有权
标题翻译：超声波血管检查仪
公开(公告)号：US08939908B2
公开(公告)日：2015-01-27
申请号：US13383866
申请日：2009-07-16
申请人： Hidenori Suzuki , Katsushi Iikubo , Chikao Harada , Hiroshi Masuda
发明人： Hidenori Suzuki , Katsushi Iikubo , Chikao Harada , Hiroshi Masuda
IPC分类号： A61B6/00 , A61B8/08 , A61B5/02 , A61B8/00
CPC分类号： A61B8/0858 , A61B5/02007 , A61B8/4218 , A61B8/461 , A61B8/5207 , A61B8/5223 , A61B8/54 , G01S7/52073 , G01S7/52074 , G01S7/52079 , G01S15/8925 , G01S15/8936
摘要： An ultrasonic blood vessel inspecting apparatus provided with a longitudinal cross sectional blood vessel image generating portion configured to generate a longitudinal cross sectional image of a blood vessel located below a skin of a live body, on the basis of reflected wave signals of an ultrasonic wave by using an ultrasonic probe placed on the skin of said live body, includes: an index value calculating portion configured to calculate an index value indicative of a degree of clarity of an image which represents an intima-media complex of said blood vessel and which exists within said longitudinal cross sectional image of the blood vessel.
摘要翻译：一种超声波血管检查装置，其具有纵剖视血管图像生成部，其构造成基于超声波的反射波信号，生成位于活体皮肤下方的血管的纵截面图像使用放置在所述活体的皮肤上的超声波探头，包括：指标值计算部，被配置为计算表示代表所述血管的内膜 - 媒体复合体的图像的清晰度的指标值，所述血管的纵向横截面图像。

8. 发明申请

US20090036776A1 Apparatus for measuring inner diameter of tubular body of living being 审中-公开
标题翻译：用于测量管状体内径的装置
公开(公告)号：US20090036776A1
公开(公告)日：2009-02-05
申请号：US11654659
申请日：2007-01-18
申请人： Hiroshi Masuda , Hitoshi Hirano , Hidenori Suzuki , Chikao Harada
发明人： Hiroshi Masuda , Hitoshi Hirano , Hidenori Suzuki , Chikao Harada
IPC分类号： A61B8/00
CPC分类号： A61B5/1075 , A61B5/418 , A61B5/6824 , A61B5/6843 , A61B5/702 , A61B8/0858 , A61B8/40 , A61B8/4218 , A61B8/4281 , A61B8/4483 , G01B17/00
摘要： An apparatus for measuring an inner diameter of a tubular body present under a skin of a living being, by emitting an ultrasonic wave from an ultrasonic probe placed on the skin, the apparatus including a reflection-signal detecting portion which detects a reflection signal that is reflected from the tubular body when the ultrasonic wave is emitted from the ultrasonic probe; and an inner-diameter calculating portion which calculates the inner diameter of the tubular body, based on an interval between two groups of reflection waves which are contained by the detected reflection signal and which are reflected from two diametrically opposed portions of a wall of the tubular body, respectively.
摘要翻译：一种用于通过从放置在皮肤上的超声波探头发射超声波来测量存在于生物皮肤下的管状体的内径的装置，该装置包括反射信号检测部分，该反射信号检测部分检测反射信号是当超声波从超声波探头发射时，从管体反射; 以及内径计算部，其基于由所检测的反射信号包含的两组反射波之间的间隔计算管状体的内径，并且从管状壁的两个直径相对的部分反射身体。

9. 发明授权

US09545241B2 Blood vessel function inspecting apparatus 有权
标题翻译：血管功能检查仪
公开(公告)号：US09545241B2
公开(公告)日：2017-01-17
申请号：US14467889
申请日：2014-08-25
申请人： Hiroshi Masuda , Chikao Harada , Hidenori Suzuki
发明人： Hiroshi Masuda , Chikao Harada , Hidenori Suzuki
IPC分类号： A61B5/02 , A61B8/08 , A61B5/022 , A61B8/06 , A61B8/00 , A61B5/0225 , G01S15/89
CPC分类号： A61B8/485 , A61B5/02035 , A61B5/02225 , A61B5/0225 , A61B8/06 , A61B8/0858 , A61B8/0891 , A61B8/4218 , A61B8/488 , A61B8/5223 , G01S15/899
摘要： It is provided a blood vessel function inspecting apparatus including: a blood vessel diameter measuring portion configured to measure a diameter of a blood vessel; a blood vessel wall thickness measuring portion configured to measure a wall thickness of the blood vessel; and a blood vessel function index value calculating portion configured to calculate a function index value for diagnosing the blood vessel of its function, after releasing of the blood vessel from blood flow obstruction, by dividing an amount of dilatation of said diameter of the blood vessel continuously measured by said blood vessel diameter measuring portion, by the wall thickness measured by said blood vessel wall thickness measuring portion.
摘要翻译：本发明提供一种血管功能检查装置，包括：血管直径测量部，被配置为测量血管的直径; 构造成测量血管壁厚的血管壁厚测量部; 以及血管功能指标值计算部，其被配置为通过将所述血管直径的扩张量连续地除以从血流阻塞释放血液之后，计算用于诊断其功能的血管的功能指标值由所述血管直径测量部分测量由所述血管壁厚度测量部分测量的壁厚。

10. 发明授权

US09089306B2 Blood vessel ultrasonic image measuring method 有权
标题翻译：血管超声图像测量方法
公开(公告)号：US09089306B2
公开(公告)日：2015-07-28
申请号：US12734045
申请日：2008-09-16
申请人： Chikao Harada , Hiroshi Masuda , Hidenori Suzuki
发明人： Chikao Harada , Hiroshi Masuda , Hidenori Suzuki
IPC分类号： A61B5/00 , A61B8/00 , G01S7/52 , A61B8/08 , G01S15/89
CPC分类号： A61B5/489 , A61B5/6835 , A61B8/0891 , A61B8/4218 , A61B8/4281 , A61B8/4483 , A61B8/4494 , A61B8/464 , A61B8/488 , G01S7/52065 , G01S15/8925 , G01S15/8936
摘要： A blood vessel ultrasonic image measuring method capable of facilitating the positioning of an ultrasonic probe and acquiring sufficient positioning accuracy. Because of inclusion of an around-X-axis positioning step of causing a multiaxis driving device to position an ultrasonic probe such that distances from respective ultrasonic array probes to the center of a blood vessel are equalized, and an X-axis direction positioning step and an around-Z-axis positioning step of causing the multiaxis driving device to position the ultrasonic probe such that the image of the blood vessel is positioned at the center portion in the width direction of the first short axis image display area and the second short axis image display area, the positioning may be performed by using the positions in the longitudinal direction of the ultrasonic array probes relative to the blood vessel or the distances of the ultrasonic array probes to the blood vessel.
摘要翻译：一种血管超声波图像测量方法，其能够促进超声波探头的定位并获得足够的定位精度。由于包含使X轴方向定位工序和多轴驱动装置定位超声波探头的X轴定位步骤，使得从各个超声波阵列探针到血管中心的距离相等，绕Z轴定位步骤，使多轴驱动装置定位超声波探头，使得血管的图像位于第一短轴图像显示区域和第二短轴图像显示区域的宽度方向上的中心部分可以通过使用超声波阵列探针相对于血管的纵向方向的位置或超声阵列探针到血管的距离来进行定位。

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