专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US5994553A Method for preparing 2-mercaptothiazole 失效
标题翻译： 2-巯基噻唑的制备方法
公开(公告)号：US5994553A
公开(公告)日：1999-11-30
申请号：US211446
申请日：1998-12-15
申请人： Katsumasa Harada , Akio Matsushita , Taku Nakamura , Katsuhiko Mizutare , Takafumi Hirakawa , Ken Ikuno , Noriaki Iwase
发明人： Katsumasa Harada , Akio Matsushita , Taku Nakamura , Katsuhiko Mizutare , Takafumi Hirakawa , Ken Ikuno , Noriaki Iwase
IPC分类号： C07D277/20 , C07D277/36
CPC分类号： C07D277/36
摘要： Disclosed is a method for preparing 2-mercaptothiazole, which comprises adding a dithiocarbamate salt represented by the formula (1): ##STR1## wherein M is a cation, to a chloroacetaldehyde solution in the presence of an acid.
摘要翻译：公开了一种2-巯基噻唑的制备方法，该方法包括在酸存在下，向氯乙醛溶液中加入由式（1）表示的二硫代氨基甲酸盐：其中M为阳离子。

2. 发明授权

US08450319B2 Pyrrolopyridazinone compound 失效
标题翻译：吡咯并哒嗪酮化合物
公开(公告)号：US08450319B2
公开(公告)日：2013-05-28
申请号：US12087864
申请日：2007-01-16
申请人： Masahiko Hagihara , Masayuki Tanaka , Tetsushi Katsube , Makoto Okudo , Noriaki Iwase , Manabu Shigetomi , Tomoko Kanda , Takayuki Nakanishi
发明人： Masahiko Hagihara , Masayuki Tanaka , Tetsushi Katsube , Makoto Okudo , Noriaki Iwase , Manabu Shigetomi , Tomoko Kanda , Takayuki Nakanishi
IPC分类号： C07D487/04 , A61K31/5025 , A61P29/00
CPC分类号： C07D487/04
摘要： The present invention discloses a pyrrolopyridazinone compound represented by the formula (1): useful, for example, as an anti-inflammatory agent or an inhibitor of respiratory tract contraction.
摘要翻译：本发明公开了由式（1）表示的吡咯并哒嗪酮化合物：例如可用作抗炎剂或呼吸道收缩抑制剂。

3. 发明申请

US20130109653A1 Substituted Pyridine Compound 有权
标题翻译：取代的吡啶化合物
公开(公告)号：US20130109653A1
公开(公告)日：2013-05-02
申请号：US13809115
申请日：2011-07-08
申请人： Tsuyoshi Nakamura , Hidenori Namiki , Naoki Terasaka , Akiko Shima , Masahiko Hagihara , Noriaki Iwase , Katsunori Takata , Osamu Kikuchi , Kazunari Tsuboike , Hiroyuki Setoguchi , Kenji Yoneda , Hidetoshi Sunamoto , Koji Ito
发明人： Tsuyoshi Nakamura , Hidenori Namiki , Naoki Terasaka , Akiko Shima , Masahiko Hagihara , Noriaki Iwase , Katsunori Takata , Osamu Kikuchi , Kazunari Tsuboike , Hiroyuki Setoguchi , Kenji Yoneda , Hidetoshi Sunamoto , Koji Ito
IPC分类号： C07D401/14 , C07D417/14 , C07F7/18 , C07D413/14
CPC分类号： C07D401/14 , C07D413/14 , C07D417/14 , C07F7/1804
摘要： The present invention provides a substituted pyridine compound or a pharmacologically acceptable salt thereof which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a compound represented by a general formula (I), wherein R1 is H, optionally substituted alkyl, OH, optionally substituted alkoxy, alkylsulfonyl, optionally substituted amino, carboxy, optionally substituted carbonyl, CN, halogeno, optionally substituted phenyl, optionally substituted aromatic heterocyclyl, optionally substituted saturated heterocyclyl, optionally substituted saturated heterocyclyloxy or optionally substituted saturated heterocyclylcarbonyl, etc., and the like.
摘要翻译：本发明提供了具有优异的CETP抑制活性并可用作药物的取代的吡啶化合物或其药学上可接受的盐。本发明提供由通式（I）表示的化合物，其中R 1为H，任选取代的烷基，OH，任选取代的烷氧基，烷基磺酰基，任选取代的氨基，羧基，任选取代的羰基，CN，卤代，任选取代的苯基，任选取代的芳族杂环基，任选取代的饱和杂环基，任选取代的饱和杂环氧基或任选取代的饱和杂环基羰基等，等等。

4. 发明授权

US07188593B2 Controller for automobile 失效
标题翻译：汽车控制器
公开(公告)号：US07188593B2
公开(公告)日：2007-03-13
申请号：US11129484
申请日：2005-05-16
申请人： Noriaki Iwase , Haruyuki Urushihata , Hisashi Iida
发明人： Noriaki Iwase , Haruyuki Urushihata , Hisashi Iida
IPC分类号： F01L1/34
CPC分类号： F02D13/0238 , F01L1/34 , F01L13/0015 , F01L2001/0537 , F01L2800/00 , F01L2820/041 , F01L2820/042 , F02D13/0207 , F02D41/1402 , F02D2041/001 , F02D2041/1433 , Y02T10/18
摘要： A control duty is obtained, which asymptotically makes the output of a control subject consistent with an output of a reference model. The output of the control subject simulates a dynamic characteristic of a variable valve timing controller, and the output of the reference model simulates an ideal input-output characteristic of the variable valve timing. The control duty makes a difference between the output of the reference model and an actual valve timing small enough. A parameter of a controller is consecutively corrected to make the difference small by means of a parameter correcting mechanism when the dynamic characteristic of the variable valve timing controller is varied due to a variation of an operating environment thereof so that the difference becomes large.
摘要翻译：获得控制任务，其渐近地使控制主体的输出与参考模型的输出一致。控制对象的输出模拟可变气门正时控制器的动态特性，参考模型的输出模拟可变气门正时的理想输入输出特性。控制负载使参考模型的输出与实际阀正时间之间的差值小。当可变气门正时控制器的动态特性由于其操作环境的变化而变化以使差异变大时，通过参数校正机构连续校正控制器的参数以使差异较小。

5. 发明授权

US08170779B2 Abnormality diagnosis device for exhaust heat recovery equipment 失效
标题翻译：废热回收设备异常诊断装置
公开(公告)号：US08170779B2
公开(公告)日：2012-05-01
申请号：US12537468
申请日：2009-08-07
申请人： Noriaki Iwase , Naoyuki Kamiya
发明人： Noriaki Iwase , Naoyuki Kamiya
IPC分类号： G06F19/00 , F01N3/02 , F01N11/00 , F01P7/16 , F01P1/06
CPC分类号： F01N5/02 , F01N11/00 , Y02T10/16 , Y02T10/47
摘要： An abnormality diagnosis device is for an exhaust heat recovery equipment including an exhaust heat absorption part absorbing exhaust heat from an engine, a heat release part releasing at least part of the heat absorbed by the absorption part to engine coolant, a circulation loop passing through the absorption part and the release part, the medium circulating around the loop, and an opening and closing valve disposed in the loop between the absorption part and the release part. The equipment closes the valve to stop circulation of the medium when coolant temperature is a preset temperature or above. The device includes an abnormality determination device for determining whether the valve is in an abnormal opening state based on a heat amount transmitted from exhaust heat to coolant through the equipment, when coolant temperature is the preset temperature or above and thereby the valve is closed if the valve is normal.
摘要翻译：异常诊断装置是一种排气热回收设备，其包括吸收来自发动机的排热的排气吸热部，将吸收部吸收的热量的至少一部分释放到发动机冷却剂的散热部，通过吸收部分和释放部分，围绕环路循环的介质，以及设置在吸收部分和释放部分之间的环中的开闭阀。当冷却液温度为预设温度或以上时，设备关闭阀门以停止介质循环。该装置包括异常判定装置，用于当冷却剂温度为预设温度或以上时，基于从废热传递到冷却剂通过设备的热量来判断阀是否处于异常打开状态，从而如果阀门关闭阀门正常。

6. 发明申请

US20100031646A1 ABNORMALITY DIAGNOSIS DEVICE FOR EXHAUST HEAT RECOVERY EQUIPMENT 失效
标题翻译：异常热回收设备异常诊断装置
公开(公告)号：US20100031646A1
公开(公告)日：2010-02-11
申请号：US12537468
申请日：2009-08-07
申请人： Noriaki Iwase , Naoyuki Kamiya
发明人： Noriaki Iwase , Naoyuki Kamiya
IPC分类号： F01N5/02 , F01N11/00
CPC分类号： F01N5/02 , F01N11/00 , Y02T10/16 , Y02T10/47
摘要： An abnormality diagnosis device is for an exhaust heat recovery equipment including an exhaust heat absorption part absorbing exhaust heat from an engine, a heat release part releasing at least part of the heat absorbed by the absorption part to engine coolant, a circulation loop passing through the absorption part and the release part, the medium circulating around the loop, and an opening and closing valve disposed in the loop between the absorption part and the release part The equipment closes the valve to stop circulation of the medium when coolant temperature is a preset temperature or above. The device includes an abnormality determination device for determining whether the valve is in an abnormal opening state based on a heat amount transmitted from exhaust heat to coolant through the equipment, when coolant temperature is the preset temperature or above and thereby the valve is closed if the valve is normal.
摘要翻译：异常诊断装置是一种排气热回收设备，其包括吸收来自发动机的排热的排气吸热部，将吸收部吸收的热量的至少一部分释放到发动机冷却剂的散热部，通过吸收部分和释放部分，围绕环路循环的介质，以及设置在吸收部分和释放部分之间的环路中的打开和关闭阀当冷却剂温度为预设温度时，设备关闭阀门以停止介质的循环或以上。该装置包括异常判定装置，用于当冷却剂温度为预设温度或以上时，基于从废热传递到冷却剂通过设备的热量来判断阀是否处于异常打开状态，从而如果阀门关闭阀门正常。

7. 发明申请

US20090036453A1 Pyrrolopyridazinone Compound 失效
公开(公告)号：US20090036453A1
公开(公告)日：2009-02-05
申请号：US12087864
申请日：2007-01-16
申请人： Masahiko Hagihara , Masayuki Tanaka , Tetsushi Katsube , Makoto Okudo , Noriaki Iwase , Manabu Shigetomi , Tomoko Kanda , Takayuki Nakanishi
发明人： Masahiko Hagihara , Masayuki Tanaka , Tetsushi Katsube , Makoto Okudo , Noriaki Iwase , Manabu Shigetomi , Tomoko Kanda , Takayuki Nakanishi
IPC分类号： A61K31/5025 , C07D487/02 , A61P11/00 , A61P9/00 , A61P37/00
CPC分类号： C07D487/04
摘要： The present invention discloses a pyrrolopyridazinone compound represented by the formula (1): wherein R1 represents C1-C2 alkyl group or halogeno C1-C2 alkyl group, R2 repersents C3-C5 cycloalkyl group, (C3-C5 cycloalkyl)C1-C2 alkyl group or C1-C3 alkyl group, R3 represents hydrogen atom, or methylene group or cis-vinylene group for forming substituted oxygen-containing hetero ring in combination with group —O—R2, R4 represents hydrogen atom, halogen atom, C1-C8 alkyl group, C2-C6 alkenyl group, C2-C6 alkynyl group, hydroxy C3-C6 alkenyl group, hydroxy C3-C6 alkynyl group, C1-C6 alkyl group substituted by substituent(s) selected from Substituent group (a), C3-C6 cycloalkyl group which may be substituted by substituent(s) selected from Substituent group (b), “C1-C3 alkyl group which is substituted by C3-C6 cycloalkyl group which may be substituted by substituent(s) selected from Substituent group (b), and which may be substituted by a hydroxy group”, an aromatic ring group or heteroaromatic ring group each of which may be substituted by a substituent(s) selected from Substituent group (c) or “C1-C2 alkyl group which is substituted by aromatic ring group or heteroaromatic ring group each of which may be substituted by group(s) selected from Substituent group (c), and which may be substituted by a hydroxy group”, Substituent group (a) represents a halogen atom, hydroxy group, cyano group, carboxy group, C1-C5 alkoxy group, halogeno C1-C4 alkoxy group, C3-C6 cycloalkoxy group, (C3-C6 cycloalkyl)C1-C2 alkoxy group, C1-C4 alkoxycarbonyl group, C2-C4 alkanoyl group, C2-C4 alkanoyloxy group or C1-C4 alkyl-substituted amino group, Substituent group (b) represents a hydroxy group or a halogen atom, Substituent group (c) represents a halogen atom, a hydroxy group, a cyano group, a nitro group, a carboxy group, C1-C5 alkoxy group, C1-C4 alkoxycarbonyl group, C2-C4 alkanoyloxy group, C1-C4 alkyl-substituted amino group or a C1-C4 alkyl group which may be substituted by a substituent(s) selected from the group consisting of (a halogen atom, a hydroxy group and a carboxy group), or a pharmaceutically acceptable salt thereof.

8. 发明申请

US20060075981A1 Controller for automobile 失效
标题翻译：汽车控制器
公开(公告)号：US20060075981A1
公开(公告)日：2006-04-13
申请号：US11129484
申请日：2005-05-16
申请人： Noriaki Iwase , Haruyuki Urushihata , Hisashi Iida
发明人： Noriaki Iwase , Haruyuki Urushihata , Hisashi Iida
IPC分类号： F01L1/34
CPC分类号： F02D13/0238 , F01L1/34 , F01L13/0015 , F01L2001/0537 , F01L2800/00 , F01L2820/041 , F01L2820/042 , F02D13/0207 , F02D41/1402 , F02D2041/001 , F02D2041/1433 , Y02T10/18
摘要： A control duty is obtained, which asymptotically makes the output of a control subject consistent with an output of a reference model. The output of the control subject simulates a dynamic characteristic of a variable valve timing controller, and the output of the reference model simulates an ideal input-output characteristic of the variable valve timing. The control duty makes a difference between the output of the reference model and an actual valve timing small enough. A parameter of a controller is consecutively corrected to make the difference small by means of a parameter correcting mechanism when the dynamic characteristic of the variable valve timing controller is varied due to a variation of an operating environment thereof so that the difference becomes large.
摘要翻译：获得控制任务，其渐近地使控制主体的输出与参考模型的输出一致。控制对象的输出模拟可变气门正时控制器的动态特性，参考模型的输出模拟可变气门正时的理想输入输出特性。控制负载使参考模型的输出与实际阀正时间之间的差值小。当可变气门正时控制器的动态特性由于其操作环境的变化而变化以使差异变大时，通过参数校正机构连续校正控制器的参数以使差异较小。

9. 发明申请

US20140213549A9 Substituted Pyridine Compound 有权
标题翻译：取代的吡啶化合物
公开(公告)号：US20140213549A9
公开(公告)日：2014-07-31
申请号：US13809115
申请日：2011-07-08
申请人： Tsuyoshi Nakamura , Hidenori Namiki , Naoki Terasaka , Akiko Shima , Masahiko Hagihara , Noriaki Iwase , Katsunori Takata , Osamu Kikuchi , Kazunari Tsuboike , Hiroyuki Setoguchi , Kenji Yoneda , Hidetoshi Sunamoto , Koji Ito
发明人： Tsuyoshi Nakamura , Hidenori Namiki , Naoki Terasaka , Akiko Shima , Masahiko Hagihara , Noriaki Iwase , Katsunori Takata , Osamu Kikuchi , Kazunari Tsuboike , Hiroyuki Setoguchi , Kenji Yoneda , Hidetoshi Sunamoto , Koji Ito
IPC分类号： C07D401/14 , C07D417/14 , C07F7/18 , C07D413/14
CPC分类号： C07D401/14 , C07D413/14 , C07D417/14 , C07F7/1804
摘要： The present invention provides a substituted pyridine compound or a pharmacologically acceptable salt thereof which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a compound represented by a general formula (I), wherein R1 is H, optionally substituted alkyl, OH, optionally substituted alkoxy, alkylsulfonyl, optionally substituted amino, carboxy, optionally substituted carbonyl, CN, halogeno, optionally substituted phenyl, optionally substituted aromatic heterocyclyl, optionally substituted saturated heterocyclyl, optionally substituted saturated heterocyclyloxy or optionally substituted saturated heterocyclylcarbonyl, etc., and the like.
摘要翻译：本发明提供了具有优异的CETP抑制活性并可用作药物的取代的吡啶化合物或其药学上可接受的盐。本发明提供由通式（I）表示的化合物，其中R 1为H，任选取代的烷基，OH，任选取代的烷氧基，烷基磺酰基，任选取代的氨基，羧基，任选取代的羰基，CN，卤代，任选取代的苯基，任选取代的芳族杂环基，任选取代的饱和杂环基，任选取代的饱和杂环氧基或任选取代的饱和杂环基羰基等，等等。

10. 发明申请

US20140005143A2 Substituted PyridineCompound 有权
标题翻译：取代的吡啶化合物
公开(公告)号：US20140005143A2
公开(公告)日：2014-01-02
申请号：US13809115
申请日：2011-07-08
申请人： Tsuyoshi Nakamura , Hidenori Namiki , Naoki Terasaka , Akiko Shima , Masahiko Hagihara , Noriaki Iwase , Katsunori Takata , Osamu Kikuchi , Kazunari Tsuboike , Hiroyuki Setoguchi , Kenji Yoneda , Hidetoshi Sunamoto , Koji Ito
发明人： Tsuyoshi Nakamura , Hidenori Namiki , Naoki Terasaka , Akiko Shima , Masahiko Hagihara , Noriaki Iwase , Katsunori Takata , Osamu Kikuchi , Kazunari Tsuboike , Hiroyuki Setoguchi , Kenji Yoneda , Hidetoshi Sunamoto , Koji Ito
IPC分类号： C07D401/14 , C07D417/14 , C07F7/18 , C07D413/14
CPC分类号： C07D401/14 , C07D413/14 , C07D417/14 , C07F7/1804
摘要： The present invention provides a substituted pyridine compound or a pharmacologically acceptable salt thereof which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a compound represented by a general formula (I), wherein R1 is H, optionally substituted alkyl, OH, optionally substituted alkoxy, alkylsulfonyl, optionally substituted amino, carboxy, optionally substituted carbonyl, CN, halogeno, optionally substituted phenyl, optionally substituted aromatic heterocyclyl, optionally substituted saturated heterocyclyl, optionally substituted saturated heterocyclyloxy or optionally substituted saturated heterocyclylcarbonyl, etc., and the like.
摘要翻译：本发明提供了具有优异的CETP抑制活性并可用作药物的取代的吡啶化合物或其药学上可接受的盐。本发明提供由通式（I）表示的化合物，其中R 1为H，任选取代的烷基，OH，任选取代的烷氧基，烷基磺酰基，任选取代的氨基，羧基，任选取代的羰基，CN，卤代，任选取代的苯基，任选取代的芳族杂环基，任选取代的饱和杂环基，任选取代的饱和杂环氧基或任选取代的饱和杂环基羰基等，等等。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式