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1. 发明授权

US06213981B1 Self-administration device for liquid medicines 有权
标题翻译：液体药物自我管理装置
公开(公告)号：US06213981B1
公开(公告)日：2001-04-10
申请号：US09256998
申请日：1999-02-25
申请人： Katsuhiro Hiejima , Takeshi Mori
发明人： Katsuhiro Hiejima , Takeshi Mori
IPC分类号： A61M5178
CPC分类号： A61M5/1424 , A61M2005/1405
摘要： A liquid medicine self-administration device which is capable of administering a liquid medicine to a patient in a single shot and with which the refilling of the liquid medicine can be performed by a one-touch operation. The device includes a casing 1 having two open ends, a port portion 2 closing one of the open ends of the casing, a reservoir 3 attached to the port portion 2 and capable of being easily deformed by pressing and of being restored to its original shape. A pushing means 4 is slidably inserted into the other open end of the casing 1 and is adapted to press and deform the reservoir 3. The pushing means 4 comprises a cylindrical member 41 inserted into the casing 1 so as to be able to slide along the inner wall of the casing 1 and a spring 42 housed within the cylindrical member 41. The device operates such that when the cylindrical member 41 is pushed down by the pushing means 4, the cylindrical member 41 is automatically held in engagement with an engaging hook 5 while engagement of the cylindrical member 41 with the engaging hook is released by a push-button operation.
摘要翻译：一种液体药物自给药装置，其能够一次性地向患者施用液体药物，并且可以通过一次触摸操作进行液体药物的补充。该装置包括具有两个开口端的壳体1，封闭壳体的开口端中的一个的端口部分2，附接到端口部分2并且能够通过按压容易地变形并且恢复到其原始形状的储存器3 。推动装置4可滑动地插入壳体1的另一开口端，并且适于压缩和变形储存器3.推动装置4包括插入壳体1中的圆柱形构件41，以便能够沿着壳体1的内壁和容纳在圆柱形构件41内的弹簧42.该装置操作使得当圆柱形构件41被推动装置4向下推动时，圆柱形构件41自动地与接合钩5卡合同时通过按钮操作来释放圆柱形构件41与接合钩的接合。

2. 发明授权

US5931193A Flow rate control device having priming mechanism 失效
标题翻译：具有启动机构的流量控制装置
公开(公告)号：US5931193A
公开(公告)日：1999-08-03
申请号：US862436
申请日：1997-05-23
申请人： Katsuhiro Hiejima , Takeshi Mori
发明人： Katsuhiro Hiejima , Takeshi Mori
IPC分类号： A61M5/168 , A61M5/14 , A61M39/22
CPC分类号： A61M39/225 , A61M2005/1403 , Y10T137/87394
摘要： A flow rate control device which does not constitute an obstruction when it is connected to a liquid medicine continuous injector, which is not influenced by the body temperature of a patient and which can perform a priming operation of the liquid medicine continuous injector in a short period of time is disclosed. The control device is provided with a reservoir, a flow rate control tube and a release valve, which are preferably incorporated in a housing. The housing is provided with a through hole such that the reservoir can be pressed by a pressing means, and is also provided with a liquid medicine inlet and a liquid medicine outlet for the reservoir. A check valve is preferably provided in the liquid medicine inlet and the flow rate control tube and the release valve are provided in the liquid medicine outlet. The flow rate control tube and the release valve are provided coaxially with each other or in parallel with each other.
摘要翻译：一种流量控制装置，其在连接到液体药物连续注射器时不构成阻塞物，其不受患者体温的影响，并且能够在短时间内进行液体药物连续注射器的起动操作的时间被披露。控制装置设置有优选地并入壳体中的储存器，流量控制管和释放阀。壳体设置有通孔，使得储存器可以被按压装置按压，并且还设置有用于储存器的液体药物入口和液体药物出口。止液阀优选设置在液体药物入口中，流量控制管和释放阀设置在药液出口中。流量控制管和释放阀彼此同轴或彼此平行地设置。

3. 发明授权

US5891102A Self-administration device for liquid drugs 失效
标题翻译：液体药物自我管理装置
公开(公告)号：US5891102A
公开(公告)日：1999-04-06
申请号：US835571
申请日：1997-04-09
申请人： Katsuhiro Hiejima , Takeshi Mori
发明人： Katsuhiro Hiejima , Takeshi Mori
IPC分类号： A61J1/14 , A61M5/14 , A61M5/142 , A61M5/178
CPC分类号： A61M5/1424 , A61M2005/1405
摘要： A self-administration device includes a cylindrical casing opened at one end but closed at the opposite end. The closed opposite end is provided with a drug inflow port and a drug outflow port. An easily deformable and restorable reservoir is housed in the casing and is held by the closed end of the casing. The inflow port and outflow port are opened to the interior of the reservoir while a pushing device is provided at the open end of the casing and is movable along an inner wall of the casing to exert a pressure on the reservoir. A control device is provided for adjusting a moving distance of the pushing device to control a dosage of a liquid drug.
摘要翻译：自动管理装置包括在一端开口但在相对端封闭的圆柱形壳体。封闭的相对端设置有药物流入口和药物流出口。容易变形和可恢复的储存器容纳在壳体中并由壳体的封闭端保持。流入口和流出口在储存器的内部开口，而推动装置设置在壳体的开口端，并且能够沿壳体的内壁移动以在储存器上施加压力。提供一种控制装置，用于调节推动装置的移动距离以控制液体药物的剂量。

4. 发明授权

US06565531B1 Drug solution delivery device 失效
标题翻译：药液输送装置
公开(公告)号：US06565531B1
公开(公告)日：2003-05-20
申请号：US09666591
申请日：2000-09-20
申请人： Takeshi Mori , Katsuhiro Hiejima , Kazuhiko Nishiyama
发明人： Takeshi Mori , Katsuhiro Hiejima , Kazuhiko Nishiyama
IPC分类号： A61M520
CPC分类号： A61M5/1454 , A61M5/31515
摘要： A drug solution delivery device comprises barrel (1) provided with a port at a distal end thereof and opened at a proximal end thereof, gasket (2) fluid-tightly and slidably arranged in the barrel, cylindrical connecting member (3) having proximal end (32) and distal end (31) to which gasket (2) is releasably connected, plunger (4) removably connected to proximal end (32) of connecting member (3), and pressed helical spring (5) arranged between gasket (2) and connecting member (3).
摘要翻译：药液输送装置包括在其远端处设置有开口并在其近端开口的桶（1），流体紧密且可滑动地布置在桶中的垫圈（2），具有近端的圆柱形连接构件（3）（32）和可释放地连接有垫圈（2）的远端（31），可移除地连接到连接构件（3）的近端（32）的柱塞（4）和布置在垫圈（2）之间的按压螺旋弹簧）和连接构件（3）。

5. 发明授权

US6027491A Self-administration device for liquid drugs 失效
标题翻译：液体药物自我管理装置
公开(公告)号：US6027491A
公开(公告)日：2000-02-22
申请号：US40291
申请日：1998-03-18
申请人： Katsuhiro Hiejima , Takeshi Mori
发明人： Katsuhiro Hiejima , Takeshi Mori
IPC分类号： A61M5/14 , A61M5/142 , A61K9/22 , A61M5/20
CPC分类号： A61M5/1424 , A61M2005/1405
摘要： A self-administration device for liquid drugs, which can be filled in a short time without troubles such as leakage and is capable of a pushing operation in one-touch. The self-administration device for liquid drugs includes a casing 1; a port portion 2; a reservoir 3 having an open end which is closed by the port portion 2 and is capable of being restored to its original shape; and pushing means 4 for pushing the reservoir 3, wherein the reservoir 3 is pressed by the pushing means 4 to inject the liquid drug. The pushing means 4 includes a cylindrical member inserted slidably into the inner wall of the casing 1, and a spring member housed in the cylindrical member. The cylindrical member and the port position 2 are respectively provided with a male hook 425 and a female hook 25, for acting as detachable mutual engagement means.
摘要翻译：一种用于液体药物的自我管理装置，其可以在短时间内填充而没有诸如泄漏的麻烦，并且能够一触即发地推动操作。用于液体药物的自我管理装置包括壳体1; 端口部分2; 具有开口端的贮存器3，该开口端由端口部分2封闭并且能够恢复到其初始形状; 以及用于推动储存器3的推压装置4，其中储存器3被推压装置4按压以注射液体药物。推动装置4包括可滑动地插入壳体1的内壁的圆柱形构件和容纳在圆柱形构件中的弹簧构件。圆柱形构件和端口位置2分别设置有阳钩425和阴钩25，用于用作可拆卸的相互接合装置。

6. 发明授权

US6139530A Liquid medicine injection apparatus utilizing negative pressure 有权
标题翻译：液体药物注射装置利用负压
公开(公告)号：US6139530A
公开(公告)日：2000-10-31
申请号：US273252
申请日：1999-03-22
申请人： Katsuhiro Hiejima , Takeshi Mori
发明人： Katsuhiro Hiejima , Takeshi Mori
IPC分类号： A61M5/20 , A61M5/145 , A61M37/00
CPC分类号： A61M5/14526
摘要： A liquid medicine injection apparatus which is capable of injecting a liquid medicine at an accurate flow rate and which does not require an excessively strong force for filling the apparatus with the liquid medicine. The apparatus includes a barrel 1 provided with a port 11 at the distal end thereof and a shaft 12 extending along the longitudinal axis thereof, a hollow plunger 2 provided at its distal end with a first gasket 3 inserted into the barrel 1 while allowing the shaft 12 of the barrel to pass therethrough, and also provided at the proximal end thereof with a closing member 4 having a vent hole 41; a second gasket 5 connected to the proximal end of the shaft 12; and outside air releasing means 6 for allowing the space between the first and second gaskets to communicate with the outside air. With such an arrangement, a liquid medicine is filled into the barrel 1 due to a negative pressure generated in a third space 25 when the plunger 2 is advanced while the liquid medicine is expelled outside due to a vacuum generated in a second space 24 when the plunger 2 is moved backward.
摘要翻译：一种液体药剂注射装置，其能够以精确的流量喷射液体药剂，并且不需要过大的力来用液体药剂填充装置。该装置包括在其远端设置有端口11的筒1和沿其纵向轴线延伸的轴12;中空柱塞2，其远端设置有插入筒1中的第一垫圈3，同时允许轴 12的筒体通过，并且在其近端还设置有具有通气孔41的封闭构件4; 连接到轴12的近端的第二垫圈5; 以及用于允许第一和第二垫圈之间的空间与外部空气连通的外部空气释放装置6。通过这样的配置，由于当柱塞2前进时由于在第三空间25中产生的负压，由于在第二空间24中产生的真空而将液体药物排出到外部时，液体药物被填充到筒体1中，柱塞2向后移动。

7. 发明授权

US08845591B2 Self-administration device for liquid medicine 有权
标题翻译：液体药物自体装置
公开(公告)号：US08845591B2
公开(公告)日：2014-09-30
申请号：US12659615
申请日：2010-03-15
申请人： Akihiko Ishizaki , Katsuhiro Hiejima , Tomohiro Uchimura
发明人： Akihiko Ishizaki , Katsuhiro Hiejima , Tomohiro Uchimura
IPC分类号： A61M5/178 , A61M37/00 , A61M5/00 , A61M5/142
CPC分类号： A61M5/1424 , A61M5/14212 , A61M2005/1405
摘要： A liquid medicine self-administration device including a flexible reservoir, an operating member, a pushing member to move with respect to the operating member and to induce pressure deformation of the reservoir, and engaging means engages the operating member. With the operating member engaged by the engaging means, the pushing member is relatively moved to the operating member based on restoring force of a spring member to push the reservoir by the pushing member. By disengaging means moving in unison with the pushing member, the engaging means is released from an engaged state with respect to the operating member, when the pushing member has moved to a predetermined location while pushing the reservoir.
摘要翻译：一种液体药物自我管理装置，包括柔性储存器，操作构件，相对于操作构件移动并且引起储存器的压力变形的推动构件，以及接合装置接合操作构件。通过由接合装置接合的操作构件，推动构件基于弹簧构件的恢复力相对移动到操作构件，以通过推动构件推动储存器。通过与推动构件一体移动的脱离装置，当推动构件已经移动到预定位置同时推动储存器时，接合装置相对于操作构件从接合状态释放。

8. 发明授权

US07282041B2 Multi lumen catheter 有权
标题翻译：多腔导管
公开(公告)号：US07282041B2
公开(公告)日：2007-10-16
申请号：US10606374
申请日：2003-06-26
申请人： Junichi Igarashi , Katsuhiro Hiejima
发明人： Junichi Igarashi , Katsuhiro Hiejima
IPC分类号： A61M3/00
CPC分类号： A61M25/003 , A61M1/3661 , A61M25/0032 , A61M25/0068 , A61M25/0074 , A61M25/0075 , A61M25/10 , A61M2025/0031
摘要： A multi lumen catheter including an inner tube having a front tip, an outer tube, a tube or lumen for inserting a guide wire, a blood extraction lumen and a blood return lumen which are formed in the outer tube and inner tube, respectively, or both in the outer tube, wherein the inner tube is inserted in the outer tube, and allowed to slide relative thereto, and the front tip is jointed to the front end of the outer tube to shut off communication of the lumens with the exterior. A multi-lumen catheter with balloon includes a balloon provided on a tabular body at a front end thereof, a blood return port and a blood extraction port provided in the tubular body on opposite sides of the balloon, and an outer cylinder slidable on the tubular body to close the blood extraction and blood return ports and the balloon.
摘要翻译：一种多腔导管，其包括分别形成在外管和内管中的具有前端，外管，管或内腔的内管，用于插入引导线，血液提取腔和血液回流腔，或两者都在外管中，其中内管插入外管中并允许其相对于其滑动，并且前尖端接合到外管的前端以切断腔与外部的连通。具有气囊的多腔导管包括设置在其前端的平板状体上的气囊，设置在所述管状体中的血液返回口和血液提取口，所述血液回收口和血液抽出口在所述气囊的相对侧上设置，身体关闭血液提取和血液回流口和气球。

9. 发明授权

US5927326A Multi stage type flow rate switching device 失效
标题翻译：多级式流量开关装置
公开(公告)号：US5927326A
公开(公告)日：1999-07-27
申请号：US892159
申请日：1997-07-14
申请人： Katsuhiro Hiejima , Yosuke Naoki
发明人： Katsuhiro Hiejima , Yosuke Naoki
IPC分类号： A61M39/00 , A61M5/14 , A61M5/168 , A61M1/14
CPC分类号： A61M5/141 , A61M5/16877 , Y10T137/87338 , Y10T137/87523
摘要： A multi-stage type flow rate switching device is provided which simplifies switching of flow paths and which rarely causes erroneous operation. The multi-stage type flow rate switching device includes a constant flow rate path 2 and a variable flow rate path 3 arranged in parallel between a liquid medicine flow inlet port 1 and a liquid medicine flow outlet port 4 where the variable flow rate path 3 can change the flow rate by means of a three-way stopcock 33. Although the flow rate can be switched in four stages when one variable flow rate path 3 is arranged as shown by FIG. 1, the flow rate can be switched in further multi-stages by providing two or more of the variable flow rate paths 3.
摘要翻译：提供了一种多级式流量切换装置，其简化了流路的切换，很少引起误操作。多级式流量切换装置包括在液体药物流入口1和液体药物流出口4之间并联配置的恒定流量路径2和可变流量路径3，其中可变流量路径3可以通过三通旋塞阀33来改变流量。尽管当一个可变流速路径3如图3所示排列时，流量可以分四个阶段进行切换。如图1所示，可以通过提供两个或更多个可变流量路径3来进一步多级切换流量。

10. 发明授权

US5839470A Three-way stopcock and flow rate control device in use thereof 失效
标题翻译：三通旋塞阀和流量控制装置在使用中
公开(公告)号：US5839470A
公开(公告)日：1998-11-24
申请号：US832510
申请日：1997-04-03
申请人： Katsuhiro Hiejima , Yosuke Naoki
发明人： Katsuhiro Hiejima , Yosuke Naoki
IPC分类号： F16K5/04 , A61M5/168 , A61M39/00 , A61M39/22 , F16K11/085 , F16K37/00 , G05D7/00 , F16K11/08
CPC分类号： A61M39/223 , A61M5/16877 , Y10T137/86871 , Y10T137/87322
摘要： A three-way stopcock and a flow rate control device having a flow rate control unit for controlling the flow rate by flow resistances of flow rate control tubes. The three-way stopcock includes a plug portion in a cylindrical shape having a liquid path in a T-like shape, a cylindrical portion having two flow inlet ports and one flow outlet port, into which the plug portion can be inserted rotatably and in a liquid tight fit, and a switch lever capable of attachably and detachably engaging with the plug portion, wherein when the liquid path of the plug portion communicates with the flow outlet portion of the cylindrical portion by rotation of the plug portion by the switching lever, the liquid path of the plug portion communicates with at least one of the two flow inlet ports of the cylindrical portion.
摘要翻译：三通旋塞阀和流量控制装置，具有流量控制单元，用于通过流量控制管的流量阻力来控制流量。三通旋塞阀包括具有T型液体通道的圆柱形形状的塞子部分，具有两个流入口和一个流出口的圆柱形部分，该塞子部分可以可旋转地插入其中液密配合，以及能够可插拔地与插塞部接合的开关杆，其中当插头部分的液体路径通过开关杆旋转插头部分而与圆柱形部分的流出口部分连通时，插头部分的液体路径与圆柱形部分的两个流入口中的至少一个连通。

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