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1. 发明申请

US20070194222A1 NUCLEAR MEDICAL APPARATUS 有权
标题翻译：核医疗器械
公开(公告)号：US20070194222A1
公开(公告)日：2007-08-23
申请号：US11671233
申请日：2007-02-05
申请人： Takuzo Takayama , Katsuhiko Fujimoto , Shigeharu Ohyu , Yasuo Sakurai , Mariko Shibata , Atsuko Sugiyama , Keisuke Hashimoto
发明人： Takuzo Takayama , Katsuhiko Fujimoto , Shigeharu Ohyu , Yasuo Sakurai , Mariko Shibata , Atsuko Sugiyama , Keisuke Hashimoto
IPC分类号： G01T1/161
CPC分类号： G01T1/2985 , A61B6/4258 , G01T1/1663
摘要： A nuclear medical apparatus for obtaining a distribution of a radioisotope in a subject by administering to a subject a radioactive medicine labeled with a radioisotope, detecting gamma rays given off from the radioisotope in a gamma-ray detecting section and counting the detected gamma rays in a count section. A correcting section is provided to correct for a count taken at the count section, by use of collection efficiency data determined according to the gamma-ray detecting section and an energy the gamma rays possesses.
摘要翻译：一种用于通过向受试者施用用放射性同位素标记的放射性药物来检测受试者中放射性同位素分布的核医疗装置，其检测伽马射线检测部分中从放射性同位素发出的γ射线，并对所检测的γ射线进行计数计数部分。提供校正部分，以通过使用根据伽马射线检测部分确定的收集效率数据和伽马射线拥有的能量来校正在计数部分获得的计数。

2. 发明授权

US07854719B2 Method of introducing ultrasonic drug and apparatus thereof 有权
标题翻译：引入超声波药物的方法及其装置
公开(公告)号：US07854719B2
公开(公告)日：2010-12-21
申请号：US11617420
申请日：2006-12-28
申请人： Katsuhiko Fujimoto , Keisuke Hashimoto , Shigeharu Ohyu
发明人： Katsuhiko Fujimoto , Keisuke Hashimoto , Shigeharu Ohyu
IPC分类号： A61B17/20
CPC分类号： A61M37/0092 , A61M2037/0007
摘要： A method of introducing an ultrasonic drug includes irradiating a low frequency sound wave onto a subject, irradiating a high frequency ultrasonic wave onto a target region of the subject, and introducing the drug into the target region.
摘要翻译：引入超声波药物的方法包括将低频声波照射到被检体上，将高频超声波照射到被检体的目标区域，将药物引入目标区域。

3. 发明授权

US07470897B2 Nuclear medical apparatus 有权
标题翻译：核医疗器械
公开(公告)号：US07470897B2
公开(公告)日：2008-12-30
申请号：US11671233
申请日：2007-02-05
申请人： Takuzo Takayama , Katsuhiko Fujimoto , Shigeharu Ohyu , Yasuo Sakurai , Mariko Shibata , Atsuko Sugiyama , Keisuke Hashimoto
发明人： Takuzo Takayama , Katsuhiko Fujimoto , Shigeharu Ohyu , Yasuo Sakurai , Mariko Shibata , Atsuko Sugiyama , Keisuke Hashimoto
IPC分类号： G12B13/00
CPC分类号： G01T1/2985 , A61B6/4258 , G01T1/1663
摘要： A nuclear medical apparatus for obtaining a distribution of a radioisotope in a subject by administering to a subject a radioactive medicine labeled with a radioisotope, detecting gamma rays given off from the radioisotope in a gamma-ray detecting section and counting the detected gamma rays in a count section. A correcting section is provided to correct for a count taken at the count section, by use of collection efficiency data determined according to the gamma-ray detecting section and an energy the gamma rays possesses.
摘要翻译：一种用于通过向受试者施用用放射性同位素标记的放射性药物来检测受试者中放射性同位素分布的核医疗装置，其检测伽马射线检测部分中从放射性同位素发出的γ射线，并对所检测的γ射线进行计数计数部分。提供校正部分，以通过使用根据伽马射线检测部分确定的收集效率数据和伽马射线拥有的能量来校正在计数部分获得的计数。

4. 发明授权

US08107589B2 Radiotherapeutic system and radiotherapeutic dose distribution measuring method 有权
标题翻译：放射治疗系统和放射治疗剂量分布测量方法
公开(公告)号：US08107589B2
公开(公告)日：2012-01-31
申请号：US12336919
申请日：2008-12-17
申请人： Yasuo Sakurai , Shigeharu Ohyu , Kyojiro Nambu , Motoji Haragashira , Masahiro Kumakura , Mariko Shibata , Katsuhiko Fujimoto , Yoichi Takada
发明人： Yasuo Sakurai , Shigeharu Ohyu , Kyojiro Nambu , Motoji Haragashira , Masahiro Kumakura , Mariko Shibata , Katsuhiko Fujimoto , Yoichi Takada
IPC分类号： A61N5/10
CPC分类号： A61N5/1048 , A61B6/027 , A61B6/4291
摘要： A detector having a collimator in a position at a specific angle with respect to a therapeutic X-ray beam is mounted to selectively detect only scattering radiation in the direction. To three-dimensionally obtain a distribution of places where scattering occurs in a patient body, a detector is rotated during irradiation and scattering radiation is measured from all of directions. After that, a reconstructing process is performed, and a distribution of occurrence of scattering radiation in the subject is three-dimensionally imaged. Since angles and amounts of X-rays scattered by Compton scattering are known theoretically, if scattering radiation at a certain angle can be detected, the number of scattering radiation at other angles can be also estimated. On the basis of the theory, images of distribution of scattering radiation sources are converted to images of distribution of absorption of radiation.
摘要翻译：具有相对于治疗性X射线束在特定角度的准直器的检测器被安装成选择性地仅检测该方向上的散射辐射。为了三维地获得在患者体内发生散射的位置的分布，在照射期间旋转检测器并且从所有方向测量散射辐射。之后，进行重建处理，并且对被摄体的散射辐射的发生分布进行三维成像。由于通过康普顿散射散射的X射线的角度和数量在理论上是已知的，因此如果能够检测到某一角度的散射辐射，则可以估计其他角度的散射辐射的数量。在理论的基础上，将散射辐射源分布的图像转换为辐射吸收分布的图像。

5. 发明申请

US20090161818A1 RADIOTHERAPEUTIC SYSTEM AND RADIOTHERAPEUTIC DOSE DISTRIBUTION MEASURING METHOD 有权
标题翻译：放射治疗系统和放射治疗剂量分布测量方法
公开(公告)号：US20090161818A1
公开(公告)日：2009-06-25
申请号：US12336919
申请日：2008-12-17
申请人： Yasuo Sakurai , Shigeharu Ohyu , Kyojiro Nambu , Motoji Haragashira , Masahiro Kumakura , Mariko Shibata , Katsuhiko Fujimoto , Yoichi Takada
发明人： Yasuo Sakurai , Shigeharu Ohyu , Kyojiro Nambu , Motoji Haragashira , Masahiro Kumakura , Mariko Shibata , Katsuhiko Fujimoto , Yoichi Takada
IPC分类号： A61B6/00 , A61N5/10
CPC分类号： A61N5/1048 , A61B6/027 , A61B6/4291
摘要： A detector having a collimator in a position at a specific angle with respect to a therapeutic X-ray beam is mounted to selectively detect only scattering radiation in the direction. To three-dimensionally obtain a distribution of places where scattering occurs in a patient body, a detector is rotated during irradiation and scattering radiation is measured from all of directions. After that, a reconstructing process is performed, and a distribution of occurrence of scattering radiation in the subject is three-dimensionally imaged. Since angles and amounts of X-rays scattered by Compton scattering are known theoretically, if scattering radiation at a certain angle can be detected, the number of scattering radiation at other angles can be also estimated. On the basis of the theory, images of distribution of scattering radiation sources are converted to images of distribution of absorption of radiation.
摘要翻译：具有相对于治疗性X射线束在特定角度的准直器的检测器被安装成选择性地仅检测该方向上的散射辐射。为了三维地获得在患者体内发生散射的位置的分布，在照射期间旋转检测器并且从所有方向测量散射辐射。之后，进行重建处理，并且对被摄体的散射辐射的发生分布进行三维成像。由于通过康普顿散射散射的X射线的角度和数量在理论上是已知的，因此如果能够检测到某一角度的散射辐射，则可以估计其他角度的散射辐射的数量。在理论的基础上，将散射辐射源分布的图像转换为辐射吸收分布的图像。

6. 发明授权

US5465625A Heat measurement apparatus for inspecting therapeutic energy waves 失效
标题翻译：用于检查治疗能量波的热测量装置
公开(公告)号：US5465625A
公开(公告)日：1995-11-14
申请号：US280546
申请日：1994-07-26
申请人： Katsuhiko Fujimoto , Satoshi Aida , Masamichi Oyanagi , Nobuki Kudo
发明人： Katsuhiko Fujimoto , Satoshi Aida , Masamichi Oyanagi , Nobuki Kudo
IPC分类号： A61B17/00 , A61B17/22 , G01H3/00 , G01H3/12 , G01H11/08 , G01L11/00 , G01L7/00 , G01K1/08
CPC分类号： G01H3/125 , A61B17/22029 , G01H3/005 , A61B2017/00712
摘要： This invention relates to a heat measurement apparatus for inspecting therapeutic energy waves, e.g. shock waves or ultrasonic waves. The heat measurement apparatus for inspecting focal position and pressure of therapeutic energy waves comprises a heat sensing sheet which changes visually or electrically according to the heat, and a marker for setting the focal position, mounted on the heat sensing sheet.
摘要翻译：本发明涉及一种用于检查治疗能量波的热测量装置，冲击波或超声波。用于检查治疗能量波的焦点位置和压力的热测量装置包括根据热量在视觉上或电气上变化的热敏片以及安装在感热片上的用于设置焦点位置的标记。

7. 发明授权

US6093148A Ultrasonic wave diagnosis apparatus 失效
标题翻译：超声波诊断仪
公开(公告)号：US6093148A
公开(公告)日：2000-07-25
申请号：US50001
申请日：1998-03-30
申请人： Katsuhiko Fujimoto
发明人： Katsuhiko Fujimoto
IPC分类号： A61B17/22 , A61B18/00 , A61N7/00 , A61B8/00
CPC分类号： A61N7/00
摘要： When an affected region is greater than a focal point of a therapy ultrasonic wave, a therapy region is set in a way to include the affected region. The focal point of the therapy ultrasonic wave is moved along a planned course designed based on the therapy region, so that it is possible to treat that whole affected region greater than the focal point. In the present invention, before an actual therapy, that is, before irradiation with the therapy ultrasonic wave, a therapy simulation is made to see whether or not a better treatment is carried out. In the therapy simulation, an applicator is moved in accordance with a planned course designed based on the therapy region. During the movement, the internal region of a human subject is continuously scanned and imaged by the ultrasonic probe. A cross-sectional image obtained is displayed together with a focal point marker representing the focal point. In this way, the applicator is moved along an actual planned course and, by observing a positional relation between the subject and the focal point, accurate checking is made to see whether or not the therapy region is set relative to the affected region.
摘要翻译：当受影响区域大于治疗超声波的焦点时，设置治疗区域以包括受影响区域。治疗超声波的焦点沿着基于治疗区域设计的计划过程移动，使得可以将整个受影响区域视为大于焦点。在本发明中，在实际治疗之前，即在用治疗超声波照射之前，进行治疗模拟，以判断是否进行更好的治疗。在治疗模拟中，根据基于治疗区域设计的计划过程来移动施放器。在运动期间，人体受试者的内部区域被超声波探头连续扫描和成像。所获得的横截面图像与表示焦点的焦点标记一起显示。以这种方式，施加器沿着实际的计划过程移动，并且通过观察被检体和焦点之间的位置关系，进行准确的检查以确定治疗区域是否相对于受影响区域设定。

8. 发明授权

US5897495A Ultrasonic wave medical treatment apparatus suitable for use under guidance of magnetic resonance imaging 失效
标题翻译：超声波医疗器械适用于磁共振成像引导下使用
公开(公告)号：US5897495A
公开(公告)日：1999-04-27
申请号：US727036
申请日：1996-10-08
申请人： Satoshi Aida , Mariko Shibata , Katsuhiko Fujimoto , Yoshiharu Ishibashi , Takuji Suzuki , Yasutoshi Ishihara , Kazuya Okamoto
发明人： Satoshi Aida , Mariko Shibata , Katsuhiko Fujimoto , Yoshiharu Ishibashi , Takuji Suzuki , Yasutoshi Ishihara , Kazuya Okamoto
IPC分类号： A61B5/055 , A61B18/00 , A61B19/00 , A61F7/00 , A61N7/02 , G01R33/28
CPC分类号： A61N7/022 , A61N7/02 , G01R33/28 , A61B2090/374
摘要： An ultrasonic wave medical treatment apparatus capable of preventing the displacement of the focal point of the ultrasonic waves from the treatment target portion within the patient, eliminating a need for re-positioning of the ultrasonic wave applicator with respect to the patient, and taking MR images to be utilized during the treatment at a high resolution. In this apparatus, the ultrasonic wave applicator can be integrally incorporated within a treatment table for carrying the patient into the MRI gantry for taking the MR images. The surface coil for taking the MR images can be provided on a surface film of a water bag in the ultrasonic wave applicator, or on a body cavity probe on which the ultrasonic transducer is also provided. The mixing rate of the coupling fluid can be adjusted, and the impedance matching between the ultrasonic transducer and the driving circuit can be maintained by minimizing the reflected electric power from the ultrasonic transducer.
摘要翻译：一种超声波医疗处理装置，其能够防止超声波的焦点从患者体内的治疗对象部位移位，消除了超声波施加器相对于患者重新定位的需要，并且取MR图像以高分辨率在治疗期间使用。在该装置中，超声波施加器可以整体地结合在处理台内，用于将病人携带到用于拍摄MR图像的MRI台架中。用于拍摄MR图像的表面线圈可以设置在超声波施加器中的水袋的表面膜上，也可以设置在也设置有超声波换能器的体腔探针上。可以调节耦合流体的混合速率，并且可以通过使来自超声换能器的反射电力最小化来维持超声换能器与驱动电路之间的阻抗匹配。

9. 发明授权

US5722411A Ultrasound medical treatment apparatus with reduction of noise due to treatment ultrasound irradiation at ultrasound imaging device 失效
标题翻译：超声波治疗装置，超声波成像装置处理超声波照射引起的噪声降低
公开(公告)号：US5722411A
公开(公告)日：1998-03-03
申请号：US681451
申请日：1996-07-23
申请人： Takuji Suzuki , Satoshi Aida , Katsuhiko Fujimoto , Mariko Shibata , Yoshiharu Ishibashi , Mamoru Izumi , Shiroh Saitoh , Kazuya Okamoto
发明人： Takuji Suzuki , Satoshi Aida , Katsuhiko Fujimoto , Mariko Shibata , Yoshiharu Ishibashi , Mamoru Izumi , Shiroh Saitoh , Kazuya Okamoto
IPC分类号： A61B5/055 , A61B8/00 , A61B17/00 , A61B19/00 , A61N7/02 , G01R33/28 , G01R33/48
CPC分类号： G01R33/28 , A61N7/02 , G01R33/4804 , A61B2017/00694 , A61B2017/00707 , A61B2017/00716 , A61B2090/374 , A61B2090/504 , A61B5/055 , A61B6/506 , A61B8/00
摘要： An ultrasound medical treatment apparatus includes an ultrasound applicator for applying ultrasound irradiation to a treatment target. The treatment apparatus also includes an ultrasound imaging device that transmits ultrasound pulses to image the treatment target. The treatment apparatus is capable of reducing noises occurring at an ultrasound imaging device due to the ultrasound irradiation generated by the ultrasound application during ultrasound medical treatment. The noises may be reduced by increasing a transmission power of the ultrasound pulses. Alternatively, the noises may be reduced by subtracting pre-recorded noise components from the ultrasound pulses received by the ultrasound imaging device, where the pre-recorded noise components are characteristic of noise occurring at the ultrasound imaging device due to the ultrasound irradiation generated by the ultrasound applicator.
摘要翻译：超声波医疗装置包括用于对治疗对象进行超声波照射的超声波施加器。治疗装置还包括超声波成像装置，其发射超声脉冲以对治疗目标进行成像。该处理装置能够在超声波医疗中由于超声波应用产生的超声波照射而能够减少超声波摄像装置产生的噪声。可以通过增加超声脉冲的发射功率来减小噪声。或者，可以通过从由超声成像装置接收的超声波脉冲中减去预先记录的噪声分量来减少噪声，其中预先记录的噪声分量是由于由超声成像装置产生的超声波照射而在超声成像装置处发生的噪声的特征超声波施加器。

10. 发明授权

US5590653A Ultrasonic wave medical treatment apparatus suitable for use under guidance of magnetic resonance imaging 失效
标题翻译：超声波医疗器械适用于磁共振成像引导下使用
公开(公告)号：US5590653A
公开(公告)日：1997-01-07
申请号：US207670
申请日：1994-03-09
申请人： Satoshi Aida , Mariko Shibata , Katsuhiko Fujimoto , Yoshiharu Ishibashi , Takuji Suzuki , Yasutoshi Ishihara , Kazuya Okamoto
发明人： Satoshi Aida , Mariko Shibata , Katsuhiko Fujimoto , Yoshiharu Ishibashi , Takuji Suzuki , Yasutoshi Ishihara , Kazuya Okamoto
IPC分类号： A61B5/055 , A61B18/00 , A61B19/00 , A61F7/00 , A61N7/02 , G01R33/28
CPC分类号： A61N7/022 , A61N7/02 , G01R33/28 , A61B2090/374
摘要： An ultrasonic wave medical treatment apparatus capable of preventing the displacement of the focal point of the ultrasonic waves from the treatment target portion within the patient, eliminating a need for re-positioning of the ultrasonic wave applicator with respect to the patient, and taking MR images to be utilized during the treatment at a high resolution. In this apparatus, the ultrasonic wave applicator can be integrally incorporated within a treatment table for carrying the patient into the MRI gantry for taking the MR images. The surface coil for taking the MR images can be provided on a surface film of a water bag in the ultrasonic wave applicator, or on a body cavity probe on which the ultrasonic transducer is also provided. The mixing rate of the coupling fluid can be adjusted, and the impedance matching between the ultrasonic transducer and the driving circuit can be maintained by minimizing the reflected electric power from the ultrasonic transducer.
摘要翻译：一种超声波医疗处理装置，其能够防止超声波的焦点从患者体内的治疗对象部位移位，消除了超声波施加器相对于患者重新定位的需要，并且取MR图像以高分辨率在治疗期间使用。在该装置中，超声波施加器可以整体地结合在处理台内，用于将病人携带到用于拍摄MR图像的MRI台架中。用于拍摄MR图像的表面线圈可以设置在超声波施加器中的水袋的表面膜上，也可以设置在也设置有超声波换能器的体腔探针上。可以调节耦合流体的混合速率，并且可以通过使来自超声换能器的反射电力最小化来维持超声换能器与驱动电路之间的阻抗匹配。

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