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    • 1. 发明授权
    • Implantable infusion pump
    • 植入式输液泵
    • US5908414A
    • 1999-06-01
    • US961372
    • 1997-10-30
    • Karl-Heinz OttoManfred WielandHans BaumannJorg-Roger Peters
    • Karl-Heinz OttoManfred WielandHans BaumannJorg-Roger Peters
    • A61M5/142A61M5/168A61K9/22
    • A61M5/14276A61M2005/14264A61M2205/0244A61M5/16804
    • An improved implantable infusion pump comprises a propellant chamber, a medicament chamber, and a throttle section. Enclosed within the throttle section is a medicament delivery system comprising a chip having a fluid path etched in an upper surface, inlet and outlet depressions formed in the chip lower and upper surfaces respectively, and a channel formed through the chip connecting the inlet with the fluid path. A planar cover, preferably transparent, covers the chip upper surface. A pair of wafers surround the chip within the throttle section and pair of silicon coatings are positioned between the chip and the pair of wafers. Various bores, apertures, and recesses are formed in the wafers, the cover, and the coatings, for permitting the medicament fluid to pass through the throttle section. An alternate embodiment employs a plurality of fluid paths and a plurality of outlets permitting different throttle resistance.
    • 改进的可植入输注泵包括推进剂室,药物室和节流部分。 封闭在节流部内的药物输送系统包括:具有在上表面蚀刻的流体路径的芯片,分别形成在芯片下表面和上表面中的入口和出口凹部;以及通过将入口与流体连接的芯片形成的通道 路径。 优选透明的平面覆盖物覆盖芯片上表面。 一对晶片围绕节流部分内的芯片,一对硅涂层位于芯片和一对晶片之间。 在晶片,盖子和涂层中形成各种孔,孔和凹槽,用于允许药物流体通过节流部分。 替代实施例采用多个流体路径和允许不同节流阻力的多个出口。