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1. 发明申请

US20050170353A1 Gene examination method for judging the onset risk of glaucoma 审中-公开
标题翻译：用于判断青光眼发病风险的基因检查方法
公开(公告)号：US20050170353A1
公开(公告)日：2005-08-04
申请号：US10509595
申请日：2003-03-19
申请人： Kaoru Asano , Takayuki Takahata , Shigehiro Numada , Akinori Masago , Yasuhiro Kouchi
发明人： Kaoru Asano , Takayuki Takahata , Shigehiro Numada , Akinori Masago , Yasuhiro Kouchi
IPC分类号： C12Q1/68 , G01N33/68
CPC分类号： G01N33/6893 , C12Q1/6883 , C12Q2600/156 , G01N33/6887 , G01N2800/168
摘要： To provide a gene examination method for predicting the onset risk of glaucoma based on the relation between a glaucoma-associated gene and the onset of glaucoma, the onset of glaucoma in future is predicted by using as an indication mutations in the gene region involving the code region and/or the upstream region of a glaucoma-associated gene. In the base sequence represented by SEQ ID NO:1, mutation(s) in at least one of the following positions are detected, i.e., the 194-, 199-, 324-, 1051-, 1084-, 1627-, 1685-, 1756-, 1853-, 2830-, 3371-, 4037- and 4364-positions.
摘要翻译：为了提供基于青光眼相关基因与青光眼发生之间的关系来预测青光眼的发病风险的基因检查方法，通过使用涉及代码的基因区域中的指示突变来预测未来的青光眼发作区域和/或青光眼相关基因的上游区域。在由SEQ ID NO：1表示的碱基序列中，检测至少一个以下位置的突变，即194-，199-，324-，1051-，1084-，1627-，1685- ，1756-，1853-，2830-，3371-4037-和4364-位。

2. 发明申请

US20070179771A1 Medical simulation system, computer system and computer program product 审中-公开
标题翻译：医疗仿真系统，计算机系统和计算机程序产品
公开(公告)号：US20070179771A1
公开(公告)日：2007-08-02
申请号：US11698393
申请日：2007-01-26
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike , Takayuki Takahata
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike , Takayuki Takahata
IPC分类号： G06G7/48 , G06G7/58
CPC分类号： G09B23/00
摘要： A medical simulation system has a replacing section for replacing at least a part of a plurality of biological function state values represented by the biological model and a simulating section for generating post-replacement simulated biological response on the basis of the biological model which reflects the replaced value.
摘要翻译：一种医疗模拟系统具有替换部分，用于代替由生物模型表示的多个生物功能状态值的至少一部分，以及用于根据反映替换的生物模型产生替代后模拟生物反应的模拟部分值。

3. 发明申请

US20070118347A1 Medical simulation system and computer program product 审中-公开
标题翻译：医疗仿真系统和计算机程序产品
公开(公告)号：US20070118347A1
公开(公告)日：2007-05-24
申请号：US11602685
申请日：2006-11-21
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike , Takayuki Takahata
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike , Takayuki Takahata
IPC分类号： G06G7/48 , G06G7/58
CPC分类号： G09B23/28
摘要： A medical simulation system includes a biological response inputting section that receives input of biological response information indicating an actual biological response of biological body, a biological model generating section that generates a biological model for reproduction of simulated response simulating the actual biological response, a pathologic condition characteristics acquiring section that acquires pathologic condition characteristics information indicating characteristics of pathologic condition of the biological body based on the generated biological model, and an outputting section that outputs the biological response information and the pathologic condition characteristics information.
摘要翻译：医疗模拟系统包括：生物反应输入部，其接收表示生物体的实际生物反应的生物反应信息的输入;生物模型生成部，其生成模拟实际生物反应的模拟响应的生物体模型;病理状态特征获取部，其基于生成的生物体模型获取表示生物体的病理状态的特征的病理状况特征信息，以及输出部，其输出生物反应信息和病理状况特征信息。

4. 发明授权

US07971425B2 Urea concentration identifying system, method for indentifying urea concentration and automobile exhaust gas reducing system using same, and method for reducing automobile exhaust gas 有权
标题翻译：尿素浓度识别系统，用于鉴别尿素浓度的方法和使用其的汽车废气还原系统，以及用于减少汽车废气的方法
公开(公告)号：US07971425B2
公开(公告)日：2011-07-05
申请号：US10527255
申请日：2003-09-10
申请人： Takayuki Takahata , Toshiaki Kawanishi , Kiyoshi Yamagishi
发明人： Takayuki Takahata , Toshiaki Kawanishi , Kiyoshi Yamagishi
IPC分类号： F01N3/00
CPC分类号： F01N3/208 , B01D53/90 , B01D53/9495 , F01N11/00 , F01N2550/05 , F01N2610/02 , F01N2610/14 , F01N2900/1811 , F01N2900/1818 , G01N27/18 , Y02A50/2325 , Y02T10/24 , Y02T10/47
摘要： The concentration of the urea of a urea solution is identified accurately and immediately. A pulse voltage is applied for a predetermined time to a urea concentration identifying sensor heater including a heater and an identifying liquid temperature sensor provided in the vicinity of the heater, a urea solution to be identified is heated by the heater, and the concentration of the urea is identified with a voltage output difference V0 corresponding to a temperature difference between an initial temperature and a peak temperature in the identifying liquid temperature sensor.
摘要翻译：精确而准确地鉴定尿素溶液的尿素浓度。向包括加热器的加热器和识别液体温度传感器的尿素浓度识别传感器加热器施加脉冲电压达预定时间，待识别的尿素溶液被加热器加热，并且浓度尿素被识别为与识别液体温度传感器中的初始温度和峰值温度之间的温度差相对应的电压输出差V0。

5. 发明申请

US20090123923A1 Method for obtaining information regarding quantity of DNA after non-methylated cytosine converting treatment in analysis of DNA methylation 审中-公开
标题翻译：在DNA甲基化分析中获得非甲基化胞嘧啶转化处理后的DNA量的方法
公开(公告)号：US20090123923A1
公开(公告)日：2009-05-14
申请号：US11987461
申请日：2007-11-30
申请人： Noriaki Yamamoto , Masahiro Kajita , Takayuki Takahata , Ayako Sakai , Hideki Ishihara
发明人： Noriaki Yamamoto , Masahiro Kajita , Takayuki Takahata , Ayako Sakai , Hideki Ishihara
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6851 , C12Q2523/125 , C12Q2531/113
摘要： The present invention provides an easy and accurate method for obtaining information regarding a quantity of DNA included in a sample used for analyzing a methylation of a target DNA, comprising steps of: treating a biological sample containing DNA including the target DNA with a non-methylated cytosine converting agent for converting non-methylated cytosine of the DNA into another base; and obtaining information regarding a quantity of DNA included in the sample treated in the treating step by using an oligonucleotide complementary to a cytosine-free region of the target DNA.
摘要翻译：本发明提供了一种用于获得关于用于分析靶DNA的甲基化的样品中包含的DNA量的信息的简单且准确的方法，包括以下步骤：用含有非甲基化的DNA包含靶DNA的生物样品用于将DNA的非甲基化胞嘧啶转化成另一种碱基的胞嘧啶转化剂; 并且通过使用与靶DNA的无胞嘧啶区域互补的寡核苷酸获得关于处理步骤中处理的样品中包含的DNA的量的信息。

6. 发明授权

US07367711B2 Type identification system for diesel oil and method for identifying type of diesel oil 有权
标题翻译：柴油机型识别系统及柴油机型识别方法
公开(公告)号：US07367711B2
公开(公告)日：2008-05-06
申请号：US10564332
申请日：2004-07-09
申请人： Toshiaki Kawanishi , Takayuki Takahata , Kiyoshi Yamagishi
发明人： Toshiaki Kawanishi , Takayuki Takahata , Kiyoshi Yamagishi
IPC分类号： G01N25/00
CPC分类号： F02D41/0025 , F02D19/0628 , F02D19/0634 , F02D19/0649 , F02D2200/0611 , G01N25/18 , G01N33/2829 , Y02T10/36
摘要： Apparatus and method for identifying type and distillation properties of light oil. A pulse voltage is applied for a predetermined period of time to a liquid type identification sensor heater comprising a heater and an identification liquid temperature sensor provided in the vicinity of the heater; the light oil to be identified is heated by the heater; and the liquid type is identified with a voltage output difference V0, corresponding to a temperature difference between the initial temperature and the peak temperature of the identification liquid temperature sensor.
摘要翻译：识别轻油类型和蒸馏性能的装置和方法。将脉冲电压施加到包括加热器的液体型识别传感器加热器和设置在加热器附近的识别液体温度传感器的预定时间段; 要识别的轻油被加热器加热; 以对应于识别液体温度传感器的初始温度和峰值温度之间的温度差的电压输出差V 0来识别液体类型。

7. 发明申请

US20070054409A1 Urea concentration identification device for urea solution 有权
标题翻译：尿素溶液尿素浓度鉴定装置
公开(公告)号：US20070054409A1
公开(公告)日：2007-03-08
申请号：US10571358
申请日：2004-09-10
申请人： Shinichi Inoue , Akiko Kubota , Takayuki Takahata
发明人： Shinichi Inoue , Akiko Kubota , Takayuki Takahata
IPC分类号： G01N33/00 , G01N25/00
CPC分类号： G01N25/18 , F01N3/2066 , F01N11/00 , F01N2610/02 , F01N2610/10 , F01N2610/148 , F01N2900/1818 , Y02T10/47 , Y10T436/171538
摘要： A urea concentration identification device comprising a concentration identification sensor unit (2) and a support unit (4) attached at the bottom end thereof with this sensor unit and provided at the top end thereof with a mounting unit (4a) to a urea solution tank opening. The concentration identification sensor unit (2) has an indirectly-heated concentration detector and liquid temperature detector provided with metal fins (21c),(22c), respectively, for heat-exchanging with urea solution. The concentration identification sensor unit (2) is provided with a cover member (2d) that forms an opposite-ends-opened urea solution induction passage so as to surround the metal fins (21c), (22c). A single-pulse voltage is applied to the heating element of the indirectly-heated concentration detector to heat it, and a urea concentration is identified at an identification operation unit based on an output from a concentration detection circuit including the temperature sensing element of the indirectly-heated concentration detector and the liquid temperature detector.
摘要翻译：一种尿素浓度识别装置，包括浓度识别传感器单元（2）和支撑单元（4），所述浓度识别传感器单元（2）和所述支撑单元（4）的底端附接有所述传感器单元，并且在其顶端处设置有安装单元（4a）到尿素溶液坦克开浓度识别传感器单元（2）具有分别具有用于与尿素溶液进行热交换的金属翅片（21c），（22c）的间接加热浓度检测器和液体温度检测器。浓度识别传感器单元（2）设置有形成以包围金属翅片（21c），（22c）的相反端开口的尿素溶液输送通路的盖部件（2d）。将单脉冲电压施加到间接加热浓度检测器的加热元件以加热，并且基于来自包括间接地温度感测元件的浓度检测电路的输出，在识别操作单元处识别尿素浓度加热浓度检测器和液体温度检测器。

8. 发明申请

US20060005620A1 Flow rate measuring method and flowmeter, flow rate measuring section package used for them and flow rate measuring unit using them, and piping leakage inspection device using flowmeter 有权
标题翻译：流量测量方法和流量计，用于它们的流量测量部件和使用它们的流量测量单元，以及使用流量计的管道泄漏检测装置
公开(公告)号：US20060005620A1
公开(公告)日：2006-01-12
申请号：US11198799
申请日：2005-08-05
申请人： Atsushi Koike , Toshiaki Kawanishi , Toshimi Nakamura , Takayuki Takahata , Kiyoshi Yamagishi
发明人： Atsushi Koike , Toshiaki Kawanishi , Toshimi Nakamura , Takayuki Takahata , Kiyoshi Yamagishi
IPC分类号： G01F1/68
CPC分类号： G01M3/2807 , G01F1/68 , G01F1/6847 , G01F1/699 , G01F7/00
摘要： Measurements are obtained by a computing unit based on an output Vh from an indirectly-heated constant-temperature controlling flow rate measuring section (16) and an output Vout from a two-constant-point temperature difference detecting flow rate measuring sections (18a, 18b). In the flow rate measuring section (16), a heating element (163) is feedback-controlled based on a detected temperature by a heat sensing element (162) to obtain an output Vh based on the feedback-controlled condition. An output Vout is obtained from flow rate measuring sections (18a, 18b) based on the detected temperature difference between a heat sensing element (182) disposed on the liquid-flow-direction upstream side of the flow-rate measuring section (16) and a temperature sensing element disposed on the downstream side. A computing unit outputs as a measurement a flow rate obtained based on the output Vh in a flow rate region where a flow rate is larger than a predetermined boundary flow rate, and outputs as a measurement a flow rate obtained based on the output Vout in a flow rate region where it is less than a boundary flow rate. Accordingly, a flow rate is measured with good precision and sensitivity over a wide flow rate range from a trace-amount flow rate region to a comparatively large flow rate region.
摘要翻译：由计算单元基于来自间接加热的恒温控制流量测量部（16）的输出Vh和来自两个恒定点温度差检测流量测量部（18a， 18 b）。在流量测量部分（16）中，基于检测到的温度由热敏元件（162）反馈控制加热元件（163），以基于反馈控制条件获得输出Vh。基于流量测量部（16）的液流方向上游侧设置的感热元件（182）之间的检测温差，从流量测量部（18a，18b）获得输出Vout，）和设置在下游侧的温度感测元件。计算单元作为测量输出在流量大于预定边界流量的流量区域中基于输出Vh获得的流量，并作为测量输出基于输出Vout获得的流量流量区域小于边界流量。因此，在从微量流量区域到较大流量区域的宽流量范围内，以高精度和高灵敏度测量流量。

9. 发明申请

US20110166792A1 INSULIN RESISTANCE EVALUATION SUPPORTING SYSTEM, INSULIN RESISTANCE EVALUATION SUPPORTING METHOD, AND COMPUTER PROGRAM PRODUCT 审中-公开
标题翻译：胰岛素抵抗评估支持系统，胰岛素抵抗评估支持方法和计算机程序产品
公开(公告)号：US20110166792A1
公开(公告)日：2011-07-07
申请号：US12979985
申请日：2010-12-28
申请人： Takayuki Takahata
发明人： Takayuki Takahata
IPC分类号： G01N33/48 , G06F19/00
CPC分类号： G16H50/50 , A61B5/14532
摘要： The present invention provides an insulin resistance evaluation supporting system, an insulin resistance evaluation supporting method, and a computer program product that can reduce the burden on a subject necessary to estimate biological information relating to the insulin resistance compared with that in conventional examples. An insulin resistance evaluation supporting system 1 includes an input/output interface 11f that receives input of information relating to a glucose concentration, an insulin concentration, and a free fatty acid concentration in blood obtained by measuring the subject, a CPU 11a that estimates a glucose uptake rate of the subject based on the information relating to the glucose concentration, the insulin concentration, and the free fatty acid concentration in the blood whose input has been received, and an image output interface 11g that outputs the estimated glucose uptake rate.
摘要翻译：本发明提供了一种胰岛素抵抗评估支持系统，胰岛素抵抗评估支持方法和计算机程序产品，其与现有实施例相比可以减少估计与胰岛素抵抗有关的生物学信息所必需的受试者的负担。胰岛素抵抗力评价支援系统1包括：输入输出接口11f，其输入与通过测定对象而得到的血液中的葡萄糖浓度，胰岛素浓度，游离脂肪酸浓度有关的信息，基于与已经接收到输入的血液中的葡萄糖浓度，胰岛素浓度和游离脂肪酸浓度相关的信息的受试者的摄取率和输出估计的葡萄糖摄取率的图像输出界面11g。

10. 发明授权

US07829024B2 Urea concentration identification device for urea solution 有权
标题翻译：尿素溶液尿素浓度鉴定装置
公开(公告)号：US07829024B2
公开(公告)日：2010-11-09
申请号：US10571357
申请日：2004-09-10
申请人： Kenjiro Izutani , Takayuki Takahata
发明人： Kenjiro Izutani , Takayuki Takahata
IPC分类号： G01N33/00 , G01N25/00 , G01N15/06
CPC分类号： F01N11/00 , F01N3/2066 , F01N2550/05 , F01N2610/02 , F01N2610/10 , F01N2610/148 , F01N2900/1818 , G01N25/18 , Y02T10/47
摘要： A urea concentration identification device comprising a concentration identification sensor unit (2) and a support unit (4) attached at the bottom end thereof with this sensor unit and provided at the top end thereof with a mounting unit (4a) to a urea solution tank opening. The concentration identification sensor unit (2) has an indirectly-heated concentration detector and liquid temperature detector provided with metal fins (21c),(22c), respectively, for heat-exchanging with urea solution. The concentration identification sensor unit (2) is provided with a cover member (2d) that forms an opposite-ends-opened urea solution induction passage so as to surround the metal fins (21c),(22c), and an enclosure (2e) that forms communication holes (26),(27) in the top and bottom end plate thereof (2e1),(2e2). A single-pulse voltage is applied to the heating element of the indirectly-heated concentration detector to heat it, and a urea concentration is identified at an identification operation unit based on an output from a concentration detection circuit including the temperature sensing element of the indirectly-heated concentration detector and the liquid temperature detector.
摘要翻译：一种尿素浓度识别装置，包括浓度识别传感器单元（2）和在其底端附接有该传感器单元的支撑单元（4），并且在其顶端处设置有安装单元（4a）到尿素溶液罐开放浓度识别传感器单元（2）具有间接加热的浓度检测器和液温检测器，分别具有用于与尿素溶液进行热交换的金属翅片（21c），（22c）。浓度识别传感器单元（2）设置有形成围绕金属翅片（21c），（22c）的外壳（2e）的两端开口的尿素溶液导入通路的盖部件（2d）在其顶板和底端板（2e1），（2e2）中形成连通孔（26），（27）。将单脉冲电压施加到间接加热浓度检测器的加热元件以加热，并且基于来自包括间接地温度感测元件的浓度检测电路的输出在识别操作单元处识别尿素浓度 - 加热浓度检测器和液体温度检测器。

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