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    • 2. 发明专利
    • Solid lipid particle preparation
    • 固体脂质制剂
    • JP2006232731A
    • 2006-09-07
    • JP2005049757
    • 2005-02-24
    • Kanebo Cosmetics Inc株式会社カネボウ化粧品
    • KUSUMARU MASAFUMIIWAMOTO YOSHIKO
    • A61K8/06A61K8/00A61K8/30A61K8/55A61K8/58A61Q5/00A61Q19/00
    • PROBLEM TO BE SOLVED: To provide a solid lipid particle emulsion which can be easily manufactured and is excellent in shelf stability.
      SOLUTION: The solid lipid particle emulsion is obtained by dispersing a lipid oil phase component comprising components (A), (B) and (C) in an aqueous phase, wherein component (A) is a triglyceride and/or a wax ester in a solid or paste form at room temperature, component (B) is a straight chain saturated higher alcohol with 12 or more carbons and component (C) is a hydrogenated phospholipid containing ≥60 mass% phosphatidylcholin. The solid lipid particle emulsion can be easily manufactured, is excellent in shelf stability and is excellent in functional characteristics when used as an external preparation.
      COPYRIGHT: (C)2006,JPO&NCIPI
    • 要解决的问题:提供可以容易地制造并且具有优异的贮存稳定性的固体脂质颗粒乳液。 解决方案:固体脂质颗粒乳液通过将包含组分(A),(B)和(C)的脂质油相组分分散在水相中而获得,其中组分(A)是甘油三酯和/或蜡 酯(B)是具有12个或更多个碳的直链饱和高级醇,组分(C)是含有≥60质量%磷脂酰胆碱的氢化磷脂。 固体脂质颗粒乳剂可以容易地制造,贮存稳定性优异,作为外用剂时的功能特性优异。 版权所有(C)2006,JPO&NCIPI