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1. 发明授权

US5908386A Fast MRI for assessment of myocardial perfusion with arrythmia insensitive magnetization preparation 失效
标题翻译：快速MRI用于评估心肌灌注与arrythmia不敏感磁化准备
公开(公告)号：US5908386A
公开(公告)日：1999-06-01
申请号：US766863
申请日：1996-12-13
申请人： Kamil Ugurbil , Nikolaos V. Tsekos , Michael G. Garwood
发明人： Kamil Ugurbil , Nikolaos V. Tsekos , Michael G. Garwood
IPC分类号： G01R33/561 , G01R33/563 , A61B5/055
CPC分类号： G01R33/56341 , G01R33/561
摘要： Contrast preparation based on Modified Driven Equilibrium Fourier Transfer generates T1 weighted images for assessment of the myocardial perfusion with contrast agent first-pass kinetics. The preparation scheme produces T1 contrast with insensitivity to arrhythmias in prospectively triggered sequential imaging thereby eliminating one of the major sources of problems in potential patient studies with previously employed contrast preparations schemes.
摘要翻译：基于改进驱动平衡傅立叶转移的对比制备产生T1加权图像，用于用造影剂首过动力学评估心肌灌注。该准备方案产生T1对比，对前瞻性触发顺序成像中的心律失常不敏感，从而消除了先前使用的对比剂制剂方案的潜在患者研究中的一个主要问题来源。

2. 发明授权

US07279899B2 Contrast from rotating frame relaxation by adiabatic pulses 有权
标题翻译：对比由绝热脉冲旋转框架松弛
公开(公告)号：US07279899B2
公开(公告)日：2007-10-09
申请号：US11244815
申请日：2005-10-06
申请人： Shalom Michaeli , Michael G. Garwood , Kamil Ugurbil , Dennis J. Sorce
发明人： Shalom Michaeli , Michael G. Garwood , Kamil Ugurbil , Dennis J. Sorce
IPC分类号： G01V3/00
CPC分类号： G01R33/446 , G01R33/50
摘要： This document discusses, among other things, a system and method for modulating transverse and longitudinal relaxation time contrast in a rotating frame based on a train of radio frequency pulses.
摘要翻译：本文件尤其涉及一种用于基于一串射频脉冲调制旋转帧中的横向和纵向弛豫时间对比度的系统和方法。

3. 发明授权

US06650116B2 Method and system for NMR using adiabatic RF pulses producing spatially quadratic phase 有权
标题翻译： NMR的方法和系统使用绝热RF脉冲产生空间二次相
公开(公告)号：US06650116B2
公开(公告)日：2003-11-18
申请号：US09961502
申请日：2001-09-24
申请人： Michael G. Garwood , Kamil Ugurbil , Lance DelaBarre , Patrick Bolan
发明人： Michael G. Garwood , Kamil Ugurbil , Lance DelaBarre , Patrick Bolan
IPC分类号： G01V300
CPC分类号： G01R33/4616 , G01R33/483
摘要： A method and system for performing MRI and NMR spectroscopy that improves the dynamic range of the received signal by using adiabatic RF pulses for spin excitation rather than for spin inversion. The preferred adiabatic RF excitation produces a spatially varying phase across the slab, and a sharp slab profile. The phase variation is divided up by a phase-encoding gradient into voxels having a phase variation that is negligible over the width of the voxel. The phase variation in the slab-select direction is, on the whole, large enough that the peak amplitude of the received signal is reduced and the signal width broadened. This reduces the dynamic range required of the analog to digital converter used in a NMR system. A NMR system suitable for carrying out the methods of the invention is also disclosed.
摘要翻译：用于执行MRI和NMR光谱的方法和系统，其通过使用绝热RF脉冲进行自旋激励而不是自旋反转来改善接收信号的动态范围。优选的绝热RF激发产生横跨板坯的空间变化的相位，并且产生锋利的板坯轮廓。相位变化通过相位编码梯度被划分成具有在体素的宽度上可忽略的相位变化的体素。平板选择方向的相位变化总体上足够大，使得接收信号的峰值幅度减小并且信号宽度变宽。这降低了在NMR系统中使用的模数转换器所需的动态范围。还公开了适用于实施本发明方法的NMR系统。

4. 发明授权

US09671481B2 Method for reducing power deposition in magnetic resonance imaging using multiband pulses and multichannel transmission 有权
公开(公告)号：US09671481B2
公开(公告)日：2017-06-06
申请号：US13995875
申请日：2011-12-20
申请人： Kamil Ugurbil
发明人： Kamil Ugurbil
IPC分类号： G01R33/54 , G01R33/483 , G01R33/3415 , G01R33/561
CPC分类号： G01R33/543 , G01R33/3415 , G01R33/4835 , G01R33/5612
摘要： A method is provided for substantially simultaneously manipulating spins in a plurality of slice locations using a magnetic resonance imaging (“MRI”) system that includes a radio frequency (“RF”) coil array composed of a plurality of RF coil elements, and in which power deposition, which may be measured as specific absorption rate (“SAR”), is reduce A plurality of slice locations to be substantially simultaneously manipulated with the MRI system are selected, and an RF transmission map (B1+map) is provided for each of the plurality of RF coil elements. A subset of slice locations to be manipulated by each of the RF coil elements is then selected using the provided RF transmission maps. Using the selected subsets of slice locations, an RF pulse to be transmitted by each of the RF coil elements is designed. The designed RF pulses are then substantially simultaneously transmitted by the MRI system to substantially simultaneously manipulate spins in each o the plurality of slice locations.

5. 发明申请

US20130342206A1 Method for Rapid Whole Brain Magnetic Resonance Imaging with Contrast Preparation 有权
标题翻译：快速全脑磁共振成像与对比准备的方法
公开(公告)号：US20130342206A1
公开(公告)日：2013-12-26
申请号：US13995869
申请日：2011-12-20
申请人： Kamil Ugurbil
发明人： Kamil Ugurbil
IPC分类号： G01R33/561
CPC分类号： G01R33/561 , G01R33/4835 , G01R33/5602
摘要： A method for acquiring image data from a plurality of slice locations in a subject with a magnetic resonance imaging (MRI) system is provided. The method includes directing the MRI system to perform a pulse sequence that includes performing a contrast preparation module configured to generate contrast-encoded longitudinal magnetization and an image encoding module configured to acquire image data from multiple slice locations substantially simultaneously. The contrast preparation module generally includes tipping longitudinal magnetization into the transverse plane to produce transverse magnetization, generating contrast-prepared transverse magnetization by establishing an image contrast in the transverse magnetization, and tipping the contrast-prepared magnetization back along the longitudinal axis to produce the contrast-encoded longitudinal magnetization.
摘要翻译：提供了一种利用磁共振成像（MRI）系统从受试者的多个切片位置获取图像数据的方法。该方法包括引导MRI系统执行脉冲序列，该脉冲序列包括执行配置成生成对比度编码的纵向磁化的对比度准备模块和被配置为基本上同时从多个切片位置获取图像数据的图像编码模块。造影剂制备模块通常包括将纵向磁化倾斜到横向平面中以产生横向磁化，通过在横向磁化中建立图像对比度产生对比度制备的横向磁化，以及沿着纵轴倾斜对比度制备的磁化以产生对比度 - 编码纵向磁化。

6. 发明申请

US20060255806A1 Assymetric radio frequency magnetic line array 有权
标题翻译：对称射频磁线阵列
公开(公告)号：US20060255806A1
公开(公告)日：2006-11-16
申请号：US11415366
申请日：2006-05-01
申请人： J. Vaughan , Gregor Adriany , Kamil Ugurbil
发明人： J. Vaughan , Gregor Adriany , Kamil Ugurbil
IPC分类号： G01V3/00
CPC分类号： G01R33/34046 , G01R33/3453
摘要： An apparatus comprises a radio frequency magnetic field unit to generate a desired magnetic field. In one embodiment, the radio frequency magnetic field unit includes a first aperture that is substantially unobstructed and a second aperture contiguous to the first aperture. In an alternative embodiment, the radio frequency magnetic field unit includes a first side aperture, a second side aperture and one or more end apertures. In one embodiment of a method, a current element is removed from a radio frequency magnetic field unit to form a magnetic field unit having an aperture. In an alternative embodiment, two current elements located opposite from one another in a radio frequency magnetic field unit are removed to form a magnetic filed unit having a first side aperture and a second side aperture.
摘要翻译：一种装置包括用于产生期望磁场的射频磁场单元。在一个实施例中，射频磁场单元包括基本无障碍的第一孔和与第一孔邻接的第二孔。在替代实施例中，射频磁场单元包括第一侧孔，第二侧孔和一个或多个端孔。在一种方法的一个实施例中，从射频磁场单元移除电流元件以形成具有孔径的磁场单元。在替代实施例中，移除在射频磁场单元中彼此相对定位的两个电流元件，以形成具有第一侧孔和第二侧孔的磁场单元。

7. 发明申请

US20050116715A1 Parallel transceiver for nuclear magnetic resonance system 有权
标题翻译：用于核磁共振系统的并行收发器
公开(公告)号：US20050116715A1
公开(公告)日：2005-06-02
申请号：US10957870
申请日：2004-10-04
申请人： J. Vaughan , Gregor Adriany , Kamil Ugurbil , John Strupp , Peter Andersen
发明人： J. Vaughan , Gregor Adriany , Kamil Ugurbil , John Strupp , Peter Andersen
IPC分类号： G01R33/32 , G01R33/34 , G01R33/3415 , G01V3/00 , G21K20060101
CPC分类号： G01R33/34046 , G01R33/246 , G01R33/3415
摘要： An excitation and detection circuit having individually controllable elements for use with a multi-element radio frequency coil. Characteristics of the driving signal, including, for example, the phase, amplitude, frequency and timing, from each element of the circuit is separately controllable using small signals. Negative feedback for the driving signal associated with each coil element is derived from a receiver coupled to that coil element.
摘要翻译：激励和检测电路具有用于与多元件射频线圈一起使用的独立可控元件。来自电路的每个元件的驱动信号的特性，包括例如相位，幅度，频率和定时的特性可以使用小信号单独控制。与每个线圈元件相关联的驱动信号的负反馈从耦合到该线圈元件的接收器导出。

8. 发明授权

US10684337B2 Multiband RF/MRI pulse design for multichannel transmitter 有权
公开(公告)号：US10684337B2
公开(公告)日：2020-06-16
申请号：US14762093
申请日：2014-01-24
申请人： Xiaoping Wu , Pierre-Francois Van De Moortele , Sebastian Schmitter , Kamil Ugurbil , Edward Auerbach
发明人： Xiaoping Wu , Pierre-Francois Van De Moortele , Sebastian Schmitter , Kamil Ugurbil , Edward Auerbach
IPC分类号： G01R33/54 , A61B5/00 , A61B5/055 , G01R33/36 , G01R33/48 , G01R33/483 , G01R33/24
摘要： A method for designing one or more multichannel, multiband radio frequency (“RF”) pulses for use with a magnetic resonance imaging (“MRI”) system is provided. The method includes determining a number of RF amplitude modulations and a number of RF phase modulations for each channel in a multichannel RF coil by minimizing an objective function that includes a complex-valued vector. The objective function also contains a system matrix that accounts for both a spatial sensitivity profile of each channel in the multichannel RF coil and a magnetic field map for each excitation band in the multiband RF pulse.

9. 发明授权

US09915717B2 Method for rapid whole brain magnetic resonance imaging with contrast preparation 有权
公开(公告)号：US09915717B2
公开(公告)日：2018-03-13
申请号：US13995869
申请日：2011-12-20
申请人： Kamil Ugurbil
发明人： Kamil Ugurbil
IPC分类号： G01V3/00 , G01R33/561 , G01R33/483 , G01R33/56
CPC分类号： G01R33/561 , G01R33/4835 , G01R33/5602
摘要： A method for acquiring image data from a plurality of slice locations in a subject with a magnetic resonance imaging (MRI) system is provided. The method includes directing the MRI system to perform a pulse sequence that includes performing a contrast preparation module configured to generate contrast-encoded longitudinal magnetization and an image encoding module configured to acquire image data from multiple slice locations substantially simultaneously. The contrast preparation module generally includes tipping longitudinal magnetization into the transverse plane to produce transverse magnetization, generating contrast-prepared transverse magnetization by establishing an image contrast in the transverse magnetization, and tipping the contrast-prepared magnetization back along the longitudinal axis to produce the contrast-encoded longitudinal magnetization.

10. 发明申请

US20120056620A1 MULTIPLICATIVE INCREASE IN MRI DATA ACQUISITION WITH MULTI-BAND RF EXCITATION PULSES IN A SIMULTANEOUS IMAGE REFOCUSING PULSE SEQUENCE 有权
标题翻译：在同时成像的图像重聚脉冲序列中，采用多波段RF激励脉冲进行磁共振数据采集的多重增加
公开(公告)号：US20120056620A1
公开(公告)日：2012-03-08
申请号：US13118179
申请日：2011-05-27
申请人： David FEINBERG , Kamil Ugurbil
发明人： David FEINBERG , Kamil Ugurbil
IPC分类号： G01R33/48
CPC分类号： G01R33/4835 , G01R33/561 , G01R33/5611 , G01R33/5615
摘要： Disclosed are methods and systems for carrying out super-multiplexed magnetic resonance imaging that entwines techniques previously used individually and independently of each other in Simultaneous Echo (of Imaging) Refocusing (SER or SIR) and Multi-Band (MB) excitation, in a single pulse sequence that provides a multiplication rather than summation of desirable effects while suppressing undesirable effects of each of the techniques that previously were used independently.
摘要翻译：公开了用于进行超多重磁共振成像的方法和系统，其在单次同时回波（成像）重聚焦（SER或SIR）和多频带（MB）激励中单独地并且彼此独立地相互混合，在单个脉冲序列提供乘法而不是期望效应的求和，同时抑制先前独立使用的每种技术的不期望的影响。

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