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1. 发明申请

US20060271097A1 Electrolytically detachable implantable devices 审中-公开
标题翻译：电解离子可植入装置
公开(公告)号：US20060271097A1
公开(公告)日：2006-11-30
申请号：US11140690
申请日：2005-05-31
申请人： Kamal Ramzipoor , Scott McGill , Michael Wallace , Sarah Young , Russell Ford
发明人： Kamal Ramzipoor , Scott McGill , Michael Wallace , Sarah Young , Russell Ford
IPC分类号： A61M29/00
CPC分类号： A61B17/12145 , A61B17/12022 , A61B17/12113 , A61B2017/12063
摘要： Described herein are electrolytically detachable implantable devices and assemblies. In particular, implantable devices and assemblies that are flexible in or near the electrolytically erodable junction region are provided. Also provided are methods of using the devices and assemblies.
摘要翻译：这里描述的是电解可拆卸的可植入装置和组件。特别地，提供了在电解可腐蚀的接合区域中或其附近柔性的可植入装置和组件。还提供了使用装置和组件的方法。

2. 发明申请

US20050137647A1 Method of intravascularly delivering stimulation leads into direct contact with tissue 失效
标题翻译：血管内传递刺激的方法导致与组织的直接接触
公开(公告)号：US20050137647A1
公开(公告)日：2005-06-23
申请号：US10744853
申请日：2003-12-22
申请人： Michael Wallace , Kamal Ramzipoor , Robert Garabedian , Robert Abrams
发明人： Michael Wallace , Kamal Ramzipoor , Robert Garabedian , Robert Abrams
IPC分类号： A61N1/05 , A61N1/18
CPC分类号： A61N1/0529 , A61N1/0531 , A61N1/0534
摘要： A method of treating a disorder in a patient is provided. The method comprises delivering a stimulation lead within a blood vessel, intralumenally puncturing a wall of the blood vessel to create an exit point, and then introducing the stimulation lead through the exit point into direct contact with tissue the stimulation of which treats the disorder. Optionally, the method comprises implanting a source of stimulation within the patient's body, and then electrically coupling the proximal end of the stimulation lead to the implanted stimulation source. Using the stimulation lead, the tissue can then be stimulated in order to treat the disorder.
摘要翻译：提供了一种治疗患者疾病的方法。该方法包括在血管内递送刺激引线，腔内穿刺血管的壁以产生出口点，然后将刺激引线通过出口点直接接触组织，其刺激治疗病症。可选地，该方法包括将刺激源植入患者体内，然后将刺激引线的近端电耦合到植入的刺激源。使用刺激铅，然后可以刺激组织以治疗该疾病。

3. 发明申请

US20060135986A1 Vaso-occlusive device having pivotable coupling 失效
标题翻译：具有可枢转耦合的血管闭塞装置
公开(公告)号：US20060135986A1
公开(公告)日：2006-06-22
申请号：US11022189
申请日：2004-12-22
申请人： Michael Wallace , Kamal Ramzipoor
发明人： Michael Wallace , Kamal Ramzipoor
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/12154 , A61B2017/00477 , A61B2017/12054 , A61B2017/12063 , A61B2017/12095
摘要： An assembly for occluding a vascular site (e.g., an aneurysm) of a human or veterinary patient includes a vaso-occlusive member, a pusher member having a distal end and a severable junction located proximal to the distal end, and a pivotable coupling that couples the pusher member to the occlusive member. A delivery catheter can be used to deliver the vaso-occlusive member to the vascular site. A method of using the assembly to occlude an aneurysm having an aneurysmal sac and an aneurysmal neck, comprises locating the catheter within the aneurysmal neck, and manipulating the pusher member to place the vaso-occlusive member within the aneurysmal sac. The method further comprises severing the severable junction to detach the vaso-occlusive member from the pusher member. As a result, an axial force is applied by the vaso-occlusive member in a proximal direction, which buckles the pivotable coupling to laterally deflect the axial force. The lateral deflection of the axial force caused by the buckling of the pivotable coupling prevents the catheter from being displaced from the aneurysmal neck by the axial force.
摘要翻译：用于闭塞人或兽医患者的血管部位（例如，动脉瘤）的组件包括血管闭塞构件，具有远端的推动器构件和位于远端附近的可分离接合部以及可枢转联接件推动器构件到闭塞构件。输送导管可用于将血管闭塞成员递送至血管部位。一种使用所述组件闭塞具有动脉瘤囊和动脉瘤颈部的动脉瘤的方法，包括将所述导管定位在所述动脉瘤颈内，以及操纵所述推动器构件以将所述血管闭塞构件置于所述动脉瘤囊内。该方法还包括切断可分开的连接点以将血管闭塞构件与推动器构件分离。结果，轴向力由近端方向由血管闭塞构件施加，该近侧方向使可枢转联接器弯曲以横向偏转轴向力。由可枢转联轴器的弯曲引起的轴向力的横向偏转防止导管通过轴向力从动脉瘤颈部移位。

4. 发明授权

US09314289B2 Cleaning device and methods 有权
标题翻译：清洁装置和方法
公开(公告)号：US09314289B2
公开(公告)日：2016-04-19
申请号：US13591991
申请日：2012-08-22
申请人： Michael Wallace , David S. Utley , Brent Gerberding , Robert Garabedian
发明人： Michael Wallace , David S. Utley , Brent Gerberding , Robert Garabedian
IPC分类号： A61B1/00 , A61B18/00 , A61B18/04 , A61B17/00 , A61B17/32
CPC分类号： A61B18/00 , A61B17/00234 , A61B18/04 , A61B2017/320008 , A61B2017/320012
摘要： An apparatus for treating tissue within a lumen may include a therapeutic or diagnostic instrument. A cleaning device may also be supported by the instrument. The cleaning device has a portion of a cleaning surface positioned proximal to the distal end of the cleaning device.
摘要翻译：用于治疗管腔内的组织的装置可以包括治疗或诊断仪器。清洁装置也可以由仪器支撑。清洁装置具有位于清洁装置的远端附近的清洁表面的一部分。

5. 发明申请

US20120108771A1 SUCCINATE-CONTAINING POLYMERIZATION CATALYST SYSTEM USING BMDS FOR PREPARATION OF POLYPROPYLENE FILM GRADE RESINS 审中-公开
标题翻译：使用BMDS制备聚丙烯薄膜树脂的含SUCCIY聚合催化剂体系
公开(公告)号：US20120108771A1
公开(公告)日：2012-05-03
申请号：US12938803
申请日：2010-11-03
申请人： Kenneth P. Blackmon , Joseph L. Thorman , Shabbir Ahmedbhai Malbari , Michael Wallace
发明人： Kenneth P. Blackmon , Joseph L. Thorman , Shabbir Ahmedbhai Malbari , Michael Wallace
IPC分类号： C08F4/602
CPC分类号： C08F10/00 , C08F110/06 , C08F4/6465 , C08F4/651 , C08F2500/04 , C08F2500/15 , C08F2500/18 , C08F2500/26
摘要： It has been discovered that using n-butylmethyldimethoxysilane (BMDS) as an external electron donor for succinate-containing Ziegler-Natta catalysts can provide a catalyst system that may prepare polypropylene films with improved properties. The catalyst systems of the invention provide for controlled chain defects/defect distribution and thus a regulated microtacticity along with broadened molecular weight distribution.
摘要翻译：已经发现，使用正丁基甲基二甲氧基硅烷（BMDS）作为含琥珀酸的齐格勒 - 纳塔催化剂的外部电子给体可提供可制备具有改进性能的聚丙烯膜的催化剂体系。本发明的催化剂体系提供受控的链缺陷/缺陷分布，从而提供调节的微量活性以及扩大的分子量分布。

6. 发明授权

US07851578B2 Succinate-containing polymerization catalyst system using n-butylmethyldimethoxysilane for preparation of polypropylene film grade resins 失效
标题翻译：含琥珀酸的聚合催化剂体系采用正丁基甲基二甲氧基硅烷制备聚丙烯薄膜级树脂
公开(公告)号：US07851578B2
公开(公告)日：2010-12-14
申请号：US11958874
申请日：2007-12-18
申请人： Kenneth P. Blackmon , Joseph L. Thorman , Shabbir Ahmedbhai Malbari , Michael Wallace
发明人： Kenneth P. Blackmon , Joseph L. Thorman , Shabbir Ahmedbhai Malbari , Michael Wallace
IPC分类号： C08F110/06
CPC分类号： C08F10/06 , C08F110/06 , Y02P20/52 , C08F4/6465 , C08F4/651 , C08F2500/12 , C08F2500/15 , C08F2500/04 , C08F2500/18
摘要： It has been discovered that using n-butylmethyldimethoxysilane (BMDS) as an external electron donor for succinate-containing Ziegler-Natta catalysts can provide a catalyst system that may prepare polypropylene films with improved properties. The catalyst systems of the invention provide for controlled chain defects/defect distribution and thus a regulated microtacticity along with broadened molecular weight distribution.
摘要翻译：已经发现，使用正丁基甲基二甲氧基硅烷（BMDS）作为含琥珀酸的齐格勒 - 纳塔催化剂的外部电子给体可提供可制备具有改进性能的聚丙烯膜的催化剂体系。本发明的催化剂体系提供受控的链缺陷/缺陷分布，从而提供调节的微量活性以及扩大的分子量分布。

7. 发明申请

US20090315258A1 INTERACTIVE GAME BOARD SYSTEM INCORPORATING CAPACITIVE SENSING AND IDENTIFICATION OF GAME PIECES 有权
标题翻译：兼容游戏板的电容式感应和识别的交互式游戏板系统
公开(公告)号：US20090315258A1
公开(公告)日：2009-12-24
申请号：US12488493
申请日：2009-06-19
申请人： Michael Wallace , Philip Trevor Odom
发明人： Michael Wallace , Philip Trevor Odom
IPC分类号： A63F3/00
CPC分类号： A63F3/00643 , A63F2003/00662 , A63F2009/2486 , G06F3/044
摘要： An interactive game board system includes a game board, a plurality of capacitive sensors embedded in the game board, a microprocessor with input channels for the capacitive sensors, computer memory means, software instructions and data for directing an interactive game, one or more playing pieces with electrically an conductive portion, and power supply means. An interactive game board system includes interdigitated sensors. An interactive game board system includes capacitive sensors operating in dynamic sensing mode. An interactive game board system includes means for identifying individual game pieces. A method of providing an interactive game board system includes providing a game board, providing capacitive sensors, providing a microprocessor with input channels for the sensors, providing, computer memory means with software instructions for operating the interactive game system, providing a plurality of game pieces with an electrically conductive portion, detecting the presence or absence of game pieces in the vicinity of the sensors, determining the future direction of game play based upon the detecting step, and providing directive feedback to game players based upon the determining step. A method of providing an interactive game board system includes identifying individual game pieces.
摘要翻译：交互式游戏板系统包括游戏板，嵌入在游戏板中的多个电容式传感器，具有用于电容式传感器的输入通道的微处理器，计算机存储装置，用于引导交互式游戏的软件指令和数据，一个或多个播放片具有导电部分和电源装置。交互式游戏板系统包括叉指传感器。交互式游戏板系统包括以动态感测模式操作的电容式传感器。交互式游戏板系统包括用于识别各个游戏件的装置。提供交互式游戏板系统的方法包括提供游戏板，提供电容式传感器，为微处理器提供用于传感器的输入通道，提供具有用于操作交互式游戏系统的软件指令的计算机存储装置，提供多个游戏件具有导电部分，检测传感器附近的游戏块的存在或不存在，基于检测步骤确定游戏的未来方向，并且基于确定步骤向游戏玩家提供指示反馈。提供交互式游戏板系统的方法包括识别各个游戏片段。

8. 发明申请

US20080167480A1 PROCESSES FOR PREPARING PYRROLES 审中-公开
标题翻译：制备吡咯的方法
公开(公告)号：US20080167480A1
公开(公告)日：2008-07-10
申请号：US11762274
申请日：2007-06-13
申请人： Michael Wallace
发明人： Michael Wallace
IPC分类号： C07D207/30
CPC分类号： C07D207/416 , C07D207/34
摘要： The present invention relates to an improved synthesis of pyrrole capping group precursors.
摘要翻译：本发明涉及吡咯封端基前体的改进合成。

9. 发明申请

US20080161515A1 Succinate-Containing Polymerization Catalyst System Using n-Butylmethyldimethoxysilane for Preparation of Polypropylene Film Grade Resins 失效
标题翻译：使用正丁基甲基二甲氧基硅烷制备聚丙烯薄膜级树脂的含琥珀酸酯聚合催化剂体系
公开(公告)号：US20080161515A1
公开(公告)日：2008-07-03
申请号：US11958874
申请日：2007-12-18
申请人： Kenneth P. Blackmon , Joseph L. Thorman , Shabbir Ahmedbhai Malbari , Michael Wallace
发明人： Kenneth P. Blackmon , Joseph L. Thorman , Shabbir Ahmedbhai Malbari , Michael Wallace
IPC分类号： C08F110/06 , C08F2/00 , B01J31/14 , B01J31/00
CPC分类号： C08F10/06 , C08F110/06 , Y02P20/52 , C08F4/6465 , C08F4/651 , C08F2500/12 , C08F2500/15 , C08F2500/04 , C08F2500/18
摘要： It has been discovered that using n-butylmethyldimethoxysilane (BMDS) as an external electron donor for succinate-containing Ziegler-Natta catalysts can provide a catalyst system that may prepare polypropylene films with improved properties. The catalyst systems of the invention provide for controlled chain defects/defect distribution and thus a regulated microtacticity along with broadened molecular weight distribution.
摘要翻译：已经发现，使用正丁基甲基二甲氧基硅烷（BMDS）作为含琥珀酸的齐格勒 - 纳塔催化剂的外部电子给体可提供可制备具有改进性能的聚丙烯膜的催化剂体系。本发明的催化剂体系提供受控的链缺陷/缺陷分布，从而提供调节的微量活性以及扩大的分子量分布。

10. 发明申请

US20070233202A1 METHOD OF STIMULATION FASTIGIUM NUCLEUS TO TREAT NEUROLOGICAL DISORDERS 有权
标题翻译：刺激核仁治疗神经病变的方法
公开(公告)号：US20070233202A1
公开(公告)日：2007-10-04
申请号：US11761330
申请日：2007-06-11
申请人： Michael Wallace , James Makous
发明人： Michael Wallace , James Makous
IPC分类号： A61N1/04
CPC分类号： A61N1/36082 , A61N1/36103
摘要： A method of treating a neurological disorder comprises introducing an electrical stimulation lead within a patient's head, locating the stimulation lead within the 4th ventricle of the patient's head, and placing the stimulation lead adjacent the fastigium nucleus of the patient's brain. The method may further comprise stimulating the fastigium nucleus with the stimulation lead to treat the neurological disorder, for example, by increasing the flow of blood within the patient's brain.
摘要翻译：治疗神经障碍的方法包括在患者头部内引入电刺激引线，将刺激引线定位在患者头部的第4 脑室内，并将刺激引线放置在邻近于病人的大脑该方法可以进一步包括用刺激引线刺激快镰核，以治疗神经障碍，例如通过增加患者脑内血液的流动。

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