专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP1637532A1 FUSED PYRIMIDINE DERIVATIVE 审中-公开
标题翻译： KONDENSIERTES PYRIMIDINDERIVAT
公开(公告)号：EP1637532A1
公开(公告)日：2006-03-22
申请号：EP04729197.6
申请日：2004-04-23
申请人： KYOWA HAKKO KOGYO CO., LTD.
发明人： NAKAJIMA, Takao , UENO, Kimihisa , NOMOTO, Yuji , MATSUMOTO, Yuichi , YANO, Hiroshi , NAKANISHI, Satoshi , TAKASAKI, Kotaro , KUSAKA, Hideaki
IPC分类号： C07D487/14 , A61K31/519 , A61P3/10 , A61P9/10 , A61P13/12 , A61P25/00 , A61P27/02
CPC分类号： C07D487/14
摘要： The present invention provides a fused pyrimidine derivative having an insulin secretion stimulating activity represented by Formula (I):

{wherein R 1 represents a hydrogen atom, lower alkyl, or the like; n represents an integer of 0 to 3; and X 1 and X 2 may be the same or different and each represents a hydrogen atom, lower alkyl, or the like; and formula (II):

represents formula (III):

[wherein X--Y--Z represents R 2 C=CR 3 -NR 4 (wherein R 2 , R 3 and R 4 may be the same or different and each represents a hydrogen atom, lower alkyl, or the like)]}, or a pharmaceutically acceptable salt thereof.
摘要翻译：本发明提供具有由式（I）表示的胰岛素分泌刺激活性的稠合嘧啶衍生物：其中R 1表示氢原子，低级烷基等; n表示0〜3的整数， X 1和X 2可以相同或不同，各自表示氢原子，低级烷基等; 和式（II）表示式（III）：[其中X-Y-Z表示R 2 C = CR 3 -NR 4（其中R 2，R 3和R 4可以相同或不同，氢原子，低级烷基等）]}或其药学上可接受的盐。

2. 发明公开

EP1092435A1 REMEDIES FOR DIABETES 有权
标题翻译：抗炎药物MEDIKAMENTE
公开(公告)号：EP1092435A1
公开(公告)日：2001-04-18
申请号：EP99926903.8
申请日：1999-07-02
申请人： KYOWA HAKKO KOGYO CO., LTD.
发明人： SHIMADA, Junichi , OHTA, Yoshihisa , TAKASAKI, Kotaro , SUDA, Miho , KUSAKA, Hideaki , YANO, Hiroshi , NAKANISHI, Satoshi , MATSUDA, Yuzuru
IPC分类号： A61K31/505
CPC分类号： C07D487/14 , A61K31/505 , A61K31/519 , Y10S514/866
摘要： A medicament for the therapeutic treatment of diabetes which comprises as an active ingredient a compound represented by the general formula (I):
wherein R 1 represents a hydrogen atom, a lower alkyl group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted aromatic heterocyclic group, R 2 represents a hydrogen atom, a lower alkyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted aromatic heterocyclic group, R 3 represents a hydrogen atom, a lower alkyl group or a substituted or unsubstituted aralkyl group, X 1 and X 2 independently represent a hydrogen atom, a lower alkyl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted aryl group, and the symbol "n" represents an integer of from 0 to 3, or a physiologically acceptable salt thereof.
摘要翻译：一种用于治疗糖尿病的药物，其包含作为活性成分的由通式（I）表示的化合物：其中R 1表示氢原子，低级烷基，取代或未取代的芳基，或取代或未取代的芳族杂环基，R 2表示氢原子，低级烷基，取代或未取代的芳烷基，取代或未取代的芳基或取代或未取代的芳族杂环基，R 3，表示氢原子，低级烷基或取代或未取代的芳烷基，X 1和X 2独立地表示氢原子，低级烷基，取代或未取代的芳烷基或取代或未取代的芳基组，符号“n”表示0〜3的整数，或其生理上可接受的盐。

3. 发明授权

EP0610519B1 ANTI-HIV DRUG 失效
标题翻译：抗艾滋病药物
公开(公告)号：EP0610519B1
公开(公告)日：1999-12-01
申请号：EP94908806.6
申请日：1993-08-20
申请人： KYOWA HAKKO KOGYO CO., Ltd.
发明人： YANO, Hiroshi , NAKANISHI, Satoshi , MATSUDA, Yuzuru , NONOMURA, Yoshiaki , SASAKI, Hiroyuki
IPC分类号： A61K31/34 , A61K31/365 , C07D307/92 , C07D493/06 , A61K31/00
CPC分类号： A61K31/365 , A61K31/00 , A61K31/34

4. 发明授权

EP1092435B1 REMEDIES FOR DIABETES 有权
标题翻译：抗糖尿病药物
公开(公告)号：EP1092435B1
公开(公告)日：2007-04-04
申请号：EP99926903.8
申请日：1999-07-02
申请人： KYOWA HAKKO KOGYO CO., LTD.
发明人： SHIMADA, Junichi , OHTA, Yoshihisa , TAKASAKI, Kotaro , SUDA, Miho , KUSAKA, Hideaki , YANO, Hiroshi , NAKANISHI, Satoshi , MATSUDA, Yuzuru
IPC分类号： A61K31/505 , A61K31/519 , C07D487/14
CPC分类号： C07D487/14 , A61K31/505 , A61K31/519 , Y10S514/866
摘要： Remedies for diabetes which contain as the active ingredient compounds represented by general formula (I) or physiologically acceptable salts thereof wherein R1 represents hydrogen, lower alkyl, optionally substituted aryl or optionally substituted heteroaryl; R2 represents hydrogen, lower alkyl, optionally substituted aralkyl, optionally substituted aryl or optionally substituted heteroaryl; R3 represents hydrogen, lower alkyl or optionally substituted aralkyl; X?1 and X2¿ independently represent each hydrogen, lower alkyl, optionally substituted aralkyl or optionally substituted aryl; and n is an integer of from 0 to 3.

5. 发明公开

EP0610519A1 ANTI-HIV DRUG 失效
标题翻译：抗HIV-MEDIKAMENT。
公开(公告)号：EP0610519A1
公开(公告)日：1994-08-17
申请号：EP94908806.6
申请日：1993-08-20
申请人： KYOWA HAKKO KOGYO CO., LTD.
发明人： YANO, Hiroshi , NAKANISHI, Satoshi , MATSUDA, Yuzuru , NONOMURA, Yoshiaki , SASAKI, Hiroyuki
IPC分类号： A61K31/34 , A61K31/365 , C07D307/92 , C07D493/06
CPC分类号： A61K31/365 , A61K31/00 , A61K31/34
摘要： An anti-HIV drug containing a myosin light-chain kinase inhibitor such as wortmannin or MS-444 as the active ingredient.
摘要翻译：含有肌球蛋白轻链激酶抑制剂如渥曼青霉素或MS-444的抗HIV药物作为活性成分。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式