专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JPH03151982A METHOD AND DEVICE FOR PERCUTANEOUS ADMINISTRATION OF PROTAIN AND PEPTIDE DRUG 失效
公开(公告)号：JPH03151982A
公开(公告)日：1991-06-28
申请号：JP28738590
申请日：1990-10-26
申请人： KOREA RES INST CHEM TECH
发明人： LEE HAI BANG , SHIN BUNG CHUL
IPC分类号： A61M5/28 , A61K9/00 , A61K9/70 , A61M37/00 , A61N1/30
摘要： PURPOSE: To efficiently perform the endermism of a medicine by bringing protein or peptide medicine impregnated in a hydrophilic polymer into contact with an ionizing solvent composition to ionize it, forming a medicine supplying passage in the surface skin layer by a plurality of skin needles, and moving the medicine into the skin by an electrical force. CONSTITUTION: An ionizing solvent is injected into a solvent storing tank 2 through a solvent injection port 7 by an injector, a releasing paper 9 is removed from administrating equipment, and the administrating equipment is pressed onto the skin by use of an adhesive layer 6. Then, the ionizing solvent composition stored in the solvent storing tank 2 dissolves the medicine within a medicine support body 3, and the medicine ionized to positive ion or negative ion is moved on the skin side by the electric repelling force with an electrode 1. On the other hand, skin needles 4 adhered to a skin needle support body 5 thrusts the surface skin layer by the pressing force when the administrating equipment is adhered to the skin to form passages allowing the pass of the medicines. When the solvent is penetrated from the solvent storing tank 2, the skin needles 4 are pulled out from the skin as the skin needle support body 5 is swollen.

2. 发明专利

DK0509122T3 未知
公开(公告)号：DK0509122T3
公开(公告)日：1996-11-18
申请号：DK91106304
申请日：1991-04-19
申请人： KOREA RES INST CHEM TECH
发明人： LEE HAI BANG , SHIN BUNG CHUL
IPC分类号： A61M5/28 , A61K9/00 , A61K9/70 , A61M37/00 , A61N1/30

3. 发明专利

DE69122494D1 未知
公开(公告)号：DE69122494D1
公开(公告)日：1996-11-07
申请号：DE69122494
申请日：1991-04-19
申请人： KOREA RES INST CHEM TECH
发明人： LEE HAI BANG , SHIN BUNG CHUL
IPC分类号： A61M5/28 , A61K9/00 , A61K9/70 , A61M37/00 , A61N1/30

4. 发明专利

AT191732T 未知
公开(公告)号：AT191732T
公开(公告)日：2000-04-15
申请号：AT94927846
申请日：1994-09-16
申请人： KOREA RES INST CHEM TECH
发明人： YUK SOON HONG , CHO SUN HAENG , LEE HAI BANG
IPC分类号： B01D69/00 , A61K9/70 , B01D67/00 , B01D71/38 , B01D71/40 , C08J9/26 , C08J9/28
摘要： PCT No. PCT/KR94/00124 Sec. 371 Date Mar. 5, 1996 Sec. 102(e) Date Mar. 5, 1996 PCT Filed Sep. 16, 1994 PCT Pub. No. WO95/09195 PCT Pub. Date Apr. 6, 1995An alkanol permeation polymer membrane prepared by dissolving biocompatible, non-allergenic polymer capable of being dissolved in polar organic solvent in methylene chloride to prepare a first solution, dissolving cellulose or glycol type polyol compounds in cosolvent composed of alkanol and methylene chloride to prepare a second solution, and mixing the first solution with the second solution, casting the mixed solution on a glass plate with a controlled thickness and evaporating may control the release of drugs effectively.

5. 发明专利

DE69122494T2 未知
公开(公告)号：DE69122494T2
公开(公告)日：1997-02-06
申请号：DE69122494
申请日：1991-04-19
申请人： KOREA RES INST CHEM TECH
发明人： LEE HAI BANG , SHIN BUNG CHUL
IPC分类号： A61M5/28 , A61K9/00 , A61K9/70 , A61M37/00 , A61N1/30

6. 发明专利

AU5272801A Solid dispersion of ipriflavone for oral administration and its manufacturing methods 未知
公开(公告)号：AU5272801A
公开(公告)日：2002-02-25
申请号：AU5272801
申请日：2001-04-17
申请人： KOREA RES INST CHEM TECH
发明人： LEE HAI BANG , KHANG GIL SON , JEONG JE KYO , KU JEUNG , CHO SUN HANG
IPC分类号： C07D311/76 , A61K9/14 , A61K31/352 , A61K47/28 , A61P19/10 , A61K9/10
摘要： This invention relates to an ipriflavone-containing pharmaceutical agent for oral administration with improved bioavailability, wherein ipriflavone is solid-dispersed in the presence of a water-soluble polymer, an absorption fortifier, and an excipient while the crystal of said pharmaceutical agent is prepared in an amorphous form at the same time so that said ipriflavone can be enclosed in said water soluble polymer, and thus even a little amount as well as lower number of dosage of said ipriflavone pharmaceutical agent can increase the effective blood concentration of said ipriflavone pharmaceutical agent and the solubility for the body fluid in the gastrointestinal tract, thereby remarkably improving the bioavailability of said agent which can much reduce both the uncomfortableness in its usage and the burden that is usually laid on the gastrointestinal tract by a heavy dose and also increase the stability during a long-term storage.

7. 发明专利

ES2093652T3 未知
公开(公告)号：ES2093652T3
公开(公告)日：1997-01-01
申请号：ES91106304
申请日：1991-04-19
申请人： KOREA RES INST CHEM TECH
发明人： LEE HAI BANG , SHIN BUNG CHUL
IPC分类号： A61M5/28 , A61K9/00 , A61K9/70 , A61M37/00 , A61N1/30

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式