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1. 发明申请

WO2016088013A1 REGISTRATION OF OPTICAL SHAPE SENSING TOOL 审中-公开
标题翻译：光学感应工具注册
公开(公告)号：WO2016088013A1
公开(公告)日：2016-06-09
申请号：PCT/IB2015/059205
申请日：2015-11-30
申请人： KONINKLIJKE PHILIPS N.V.
发明人： BHARAT, Shyam , DEHGHAN MARVAST, Ehsan , FLEXMAN, Molly Lara , KRUECKER, Jochen , DREYER, Marissa Patricia , TAHMASEBI MARAGHOOSH, Amir Mohammad
IPC分类号： A61B17/34 , A61B5/06 , A61N5/10
CPC分类号： A61B8/0841 , A61B5/061 , A61B8/58 , A61B17/3403 , A61B34/20 , A61B2017/3411 , A61B2017/3413 , A61B2034/2061 , A61N5/1007
摘要： An intervention system employs an optical shape sensing tool (32) (e.g., a brachytherapy needle having embedded optical fiber(s)) and a grid (50, 90) for guiding an insertion of the optical shape sensing tool (32) into an anatomical region relative to a grid coordinate system. The intervention system further employs a registration controller (74) for reconstructing a segment or an entirety of a shape of the optical shape sensing tool (32) relative to a needle coordinate system, and for registering the needle coordinate system to the grid coordinate system as a function of a reconstructed segment/entire shape of the optical shape sensing tool (32) relative to the grid (50, 90) (i.e., reconstruction of a segment/entire shape of the OSS needle inserted into/through the grid serving as a basis for the grid/needle coordinate system registration).
摘要翻译：介入系统采用光学形状感测工具（32）（例如，具有嵌入式光纤的近距离放射治疗针）和用于将光学形状感测工具（32）插入到解剖学中的格栅（50,90）区域相对于网格坐标系。介入系统还采用对准控制器（74），用于相对于针坐标系重建光学形状检测工具（32）的形状的一部分或全部，并且用于将针坐标系记录到网格坐标系中，作为相对于格栅（50,90）的光学形状检测工具（32）的重建段/整个形状的功能（即，重新插入插入/穿过格栅的OSS针的整个形状/ 网格/针坐标系注册的基础）。

2. 发明申请

WO2015169498A1 TREATMENT PLANNING SYSTEM 审中-公开
标题翻译：治疗计划系统
公开(公告)号：WO2015169498A1
公开(公告)日：2015-11-12
申请号：PCT/EP2015/056108
申请日：2015-03-23
申请人： KONINKLIJKE PHILIPS N.V. , SUNNYBROOK HEALTH SCIENCES CENTRE
发明人： AMTHOR, Thomas Erik , UHLEMANN, Falk , BHARAT, Shyam , DEHGHAN MARVAST, Ehsan , KUNG, Cynthia Ming-fu , RAVI, Ananth , KRUECKER, Jochen
IPC分类号： A61N5/10
CPC分类号： A61N5/103 , A61N5/1027 , A61N2005/1041
摘要： The generation of the pattern and for the adaptation to the specific geometry requires a lot of manual work. It is an object of the invention to simplify the workflow for the clinician during treatment planning. This object is achieved by a treatment planning system configured for determining a set of catheter or needle insertion positions to be used during treatment comprising. The treatment planning system comprises an image providing module for providing a medical image from which at least one treatment target structure can be derived. Further the treatment planning system comprises a pattern providing module for providing one or a set of standard patterns for catheter or needle insertion comprising a plurality of catheter or needle insertion positions, wherein the catheter or needle positions relate to treatment positions in the at least one treatment target structure.
摘要翻译：模式的生成和适应特定几何需要大量的人工工作。本发明的一个目的是简化治疗计划期间临床医生的工作流程。该目的通过一种治疗计划系统来实现，所述治疗计划系统被配置用于确定在治疗期间使用的一组导管或针插入位置，包括。治疗计划系统包括用于提供医学图像的图像提供模块，从该图像可以导出至少一个治疗目标结构。此外，治疗计划系统包括模式提供模块，用于提供包括多个导管或针插入位置的导管或针插入的一个或一组标准图案，其中导管或针位置涉及至少一个治疗中的治疗位置目标结构。

3. 发明申请

WO2015087217A1 REAL-TIME FUSION OF ANATOMICAL ULTRASOUND INFORMATION AND RADIATION DELIVERY INFORMATION FOR RADIATION THERAPIES 审中-公开
标题翻译：解剖学信息的实时融合和辐射治疗的辐射传递信息
公开(公告)号：WO2015087217A1
公开(公告)日：2015-06-18
申请号：PCT/IB2014/066616
申请日：2014-12-05
申请人： KONINKLIJKE PHILIPS N.V.
发明人： BHARAT, Shyam , DEHGHAN MARVAST, Ehsan , JAIN, Ameet Kumar , TAHMASEBI MARAGHOOSH, Amir Mohammad , VIGNON, Francois Guy Gerard Marie
IPC分类号： A61N5/10 , A61B19/00
CPC分类号： A61N5/1039 , A61B6/032 , A61B8/0833 , A61B8/4483 , A61B8/483 , A61B2090/3929 , A61N5/1038 , A61N5/1067 , A61N2005/1051 , A61N2005/1058 , A61N2005/1061
摘要： A radiation therapy delivery system (10) includes an ultrasound imaging unit (26), a radiation therapy delivery mechanism (12, 56, 70, 88), a plurality of fiducials (22, 90) located internal to the subject, an image fusion unit (40), and a delivery evaluation unit (38). The ultrasound imaging unit (26) includes a transducer (30) that emits ultrasonic sound waves to image in real-time an anatomic portion of a subject (16) in a first coordinate system. The radiation therapy delivery mechanism (12, 56, 70, 88) delivers amounts of therapeutic radiation in the anatomic portion of the subject in a second coordinate system. The fiducials (22, 90) include implants or a trans-rectal ultrasound probe (80). The image fusion unit (40) registers locations of the plurality of fiducials to at least one of the first and the second coordinate system and tracks the locations of the fiducials in real-time. The delivery evaluation unit (38) identifies locations and the amounts of delivered therapeutic radiation relative to the imaged real-time anatomic portion of the subject.
摘要翻译：放射治疗递送系统（10）包括超声成像单元（26），放射线治疗递送机构（12,56,70,88），位于对象内部的多个基准点（22,90），图像融合单元（40）和传送评估单元（38）。超声波成像单元（26）包括发射超声波以实时成像第一坐标系中的被摄体（16）的解剖部分的换能器（30）。辐射治疗递送机构（12,56,70,88）在第二坐标系统中在受试者的解剖部分中传送治疗辐射量。基准（22,90）包括植入物或经直肠超声探头（80）。图像融合单元（40）将多个基准的位置记录到第一和第二坐标系中的至少一个，并且实时地跟踪基准的位置。递送评估单元（38）识别相对于被摄体的被成像的实时解剖部分递送的治疗辐射的位置和量。

4. 发明申请

WO2014091330A1 ASSISTING APPARATUS FOR ASSISTING IN PERFORMING A BRACHYTHERAPY 审中-公开
标题翻译：辅助设备进行BRACHYTHERAPY的协助
公开(公告)号：WO2014091330A1
公开(公告)日：2014-06-19
申请号：PCT/IB2013/059989
申请日：2013-11-08
申请人： KONINKLIJKE PHILIPS N.V.
发明人： DEHGHAN MARVAST, Ehsan , TAHMASEBI MARAGHOOSH, Amir Mohammad , BHARAT, Shyam , DALAL, Sandeep M. , KUNG, Cynthia Ming-fu , KRUECKER, Jochen
IPC分类号： A61N5/10 , A61B8/08 , G06T5/50 , G06T7/00 , A61B19/00
CPC分类号： A61N5/1071 , A61B8/0833 , A61B8/0841 , A61B8/4245 , A61B8/483 , A61B8/5269 , A61B2017/3411 , A61B2034/104 , A61B2034/2051 , A61B2090/378 , A61N5/1007 , A61N5/1027 , A61N5/103 , A61N5/1048 , A61N2005/1012 , A61N2005/1024 , A61N2005/1074
摘要： The invention relates to an assisting apparatus for assisting in performing brachytherapy. The position of an introduction element (17) like a catheter is tracked particularly by using electromagnetic tracking, while a group of seeds is introduced into a living object (2). This provides a rough knowledge about the position of the seeds within the object. An ultrasound image showing the group is generated depending on the tracked position of the introduction element and, thus, depending on the rough knowledge about the position of the seeds, in order to optimize the ultrasound visualization with respect to showing the introduced seeds. Based on this optimized ultrasound visualization the position of a seed of the group is determined, thereby allowing for an improved determination of seed positions and correspondingly for an improved brachytherapy performed based on the determined positions.
摘要翻译：本发明涉及一种用于辅助进行近距离放射治疗的辅助装置。特别是通过使用电磁跟踪来跟踪导管元件（17）的位置，同时将一组种子引入到活体（2）中。这提供了关于种子在对象内的位置的粗略知识。取决于导入元件的跟踪位置产生示出组的超声波图像，并且因此根据关于种子位置的粗略知识来生成，以便优化关于显示引入的种子的超声可视化。基于这种优化的超声可视化，确定组的种子的位置，从而允许改善种子位置的确定，并且相应地基于确定的位置进行改进的近距离放射治疗。

5. 发明申请

WO2014013418A2 DETERMINATION APPARATUS FOR DETERMINING THE POSE AND SHAPE OF AN INTRODUCTION ELEMENT 审中-公开
标题翻译：用于确定引言元素的位置和形状的确定装置
公开(公告)号：WO2014013418A2
公开(公告)日：2014-01-23
申请号：PCT/IB2013/055813
申请日：2013-07-15
申请人： KONINKLIJKE PHILIPS N.V.
发明人： BHARAT, Shyam , DEHGHAN MARVAST, Ehsan , KRUECKER, Jochen , KUNG, Cynthia, Ming-fu
IPC分类号： A61N5/10
CPC分类号： A61N5/1007 , A61B2034/2051 , A61B2034/2055 , A61B2090/378 , A61N5/1027 , A61N5/103 , A61N2005/1012 , A61N2005/1018
摘要： The invention relates to a determination apparatus for determining the pose and shape of an introduction element like a catheter within a living being, wherein the introduction element (12) is adapted to be used by a brachytherapy apparatus for introducing a radiation source (10) close to a target object (11) to be treated. A position determination element (27) like guidewire (20) with an electromagnetic tracking element (16) is introduced into the introduction element (12) such that it is arranged at different locations within the introduction element (12), wherein the positions of the position determination element (27) within the introduction element (12) are determined. The determined positions are then acquired depending on the determined positions for determining the pose and shape of the introduction element within the living being. This can lead to a determination procedure with reduced user interaction, thereby simplifying the determination procedure for the user.
摘要翻译：本发明涉及一种确定装置，用于确定诸如导管在内的导入元件的姿势和形状，其中引入元件（12）适于由近距离放射治疗装置使用以将辐射源（10）接近到待处理的目标物体（11）。具有电磁跟踪元件（16）的类似导丝（20）的位置确定元件（27）被引入到引入元件（12）中，使得其布置在引入元件（12）内的不同位置处，其中确定引入元件（12）内的位置确定元件（27）。然后根据用于确定生物体内的引入元件的姿势和形状的确定位置获取确定的位置。这可以导致具有减少的用户交互的确定过程，从而简化了用户的确定过程。

6. 发明申请

WO2017089360A1 STRUCTURED FINDING OBJECTS FOR INTEGRATION OF THIRD PARTY APPLICATIONS IN THE IMAGE INTERPRETATION WORKFLOW 审中-公开
标题翻译：在图像解释工作流程中集成第三方应用程序的结构化查找对象
公开(公告)号：WO2017089360A1
公开(公告)日：2017-06-01
申请号：PCT/EP2016/078478
申请日：2016-11-22
申请人： KONINKLIJKE PHILIPS N.V.
发明人： SEVENSTER, Merlijn , MANKOVICH, Gabriel, Ryan , TELLIS, Ranjith, Naveen , DEHGHAN MARVAST, Ehsan , QIAN, Yuechen
IPC分类号： G06F19/00
CPC分类号： G06F19/321 , G06F3/0481 , G06F17/241 , G06F17/243 , G06F17/248 , G06F17/28 , G06F19/00 , G06T7/0012 , G16H10/60 , G16H15/00 , G16H40/63
摘要： A radiology workstation (16) includes a display device (25) and at least one user input device (20, 22, 24). A server computer (10) is programmed to operate with the radiology workstation to perform the radiology reading task (14) including a radiology reading support method comprising: receiving user input identifying a radiological finding; retrieving a structured finding object (SFO) template for the radiological finding; displaying an SFO annotation graphical user interface (GUI) dialog (40) having annotation data entry fields for annotating the retrieved SFO template; building an SFO (60) representing the radiological finding by annotating the SFO template via the SFO GUI dialog; and generating natural language text describing the radiological finding from the SFO. Application program interface (API) action rules (54) may be applied to determine whether the SFO being built satisfies any API action rule, and if so a corresponding application program is invoked.
摘要翻译：放射工作站（16）包括显示设备（25）和至少一个用户输入设备（20,22,24）。服务器计算机（10）被编程为与放射工作站一起操作以执行包括放射学阅读支持方法的放射学阅读任务（14），所述放射学阅读支持方法包括：接收识别放射学发现的用户输入; 检索用于放射性发现的结构化查找对象（SFO）模板; 显示具有用于注释所检索的SFO模板的注释数据输入字段的SFO注释图形用户界面（GUI）对话框（40）通过SFO GUI对话框注释SFO模板来建立表示放射性发现的SFO（60）; 并产生描述来自SFO的放射性发现的自然语言文本。可以应用应用程序接口（API）动作规则（54）来确定正在构建的SFO是否满足任何API动作规则，并且如果是，则调用相应的应用程序。

7. 发明申请

WO2017071965A1 ADAPTIVE TREATMENT PLANNING FOR HYPERTHERMIA-ENHANCED RADIATION THERAPY 审中-公开
标题翻译：高温放射治疗的适应性治疗计划
公开(公告)号：WO2017071965A1
公开(公告)日：2017-05-04
申请号：PCT/EP2016/074609
申请日：2016-10-13
申请人： KONINKLIJKE PHILIPS N.V.
发明人： BHARAT, Shyam , ANAND, Ajay , STARUCH, Robert, Michael , SETHURAMAN, Shriram , PARTHASARATHY, Vijay , DEHGHAN MARVAST, Ehsan
IPC分类号： A61N5/10 , A61N7/02
CPC分类号： A61N5/1048 , A61N5/1037 , A61N5/1038 , A61N5/1039 , A61N7/02 , A61N2005/1087
摘要： A method includes generating a hyperthermia heat plan for tissue of interest, generating a hyperthermia adapted radiation therapy plan for the tissue of interest, controlling a heat source (126) to deliver heat to the tissue of interest according to the hyperthermia heat plan, and controlling a radiation source of a radiation therapy system (100) to deliver radiation to the tissue of interest according to the hyperthermia adapted radiation therapy plan. A system includes a radiation treatment planner (124) configured to generate a hyperthermia adapted radiation therapy plan for the tissue of interest, a radiation therapy system (100) configured to deliver radiation in accordance with the hyperthermia adapted radiation therapy plan, and a hyperthermia heat delivery system (126) configured to deliver heat in accordance with a hyperthermia plan.
摘要翻译：一种方法包括生成感兴趣组织的高热加热计划，生成针对感兴趣组织的高热适应放射疗法计划，控制热源（126）以将热量传递至感兴趣组织并且控制放射疗法系统（100）的辐射源以根据适合高热的放射疗法计划向所关注的组织递送辐射。一种系统包括：辐射治疗计划器（124），被配置为生成针对感兴趣组织的高热适应放射疗法计划;辐射治疗系统（100），被配置为根据高热适应放射疗法计划递送辐射;以及高温热量输送系统（126），其被配置为根据高热计划输送热量。

8. 发明申请

WO2016092463A1 ADAPTIVE PLANNING AND DELIVERY OF HIGH DOSE RATE BRACHYTHERAPY 审中-公开
标题翻译：自适应规划和交付高剂量率的BRACHYTHERAPY
公开(公告)号：WO2016092463A1
公开(公告)日：2016-06-16
申请号：PCT/IB2015/059429
申请日：2015-12-08
申请人： KONINKLIJKE PHILIPS N.V.
发明人： DEHGHAN MARVAST, Ehsan , BHARAT, Shyam , KRUECKER, Jochen
IPC分类号： A61N5/10
CPC分类号： A61N5/1027 , A61B2034/2051 , A61B2034/2055 , A61B2034/2061 , A61B2034/2065 , A61B2090/378 , A61N5/1038 , A61N5/1067
摘要： A system for dynamic localization of medical instruments includes an ultrasound imaging system (110) configured to image a volume where one or more medical instruments are deployed. A registration module (136) registers two images of the one or more medical instruments to compute a transform between the two images, the two images being separated in time. A planning module (142) is configured to have positions of the volume and the one or more medical instruments updated based on the transform and, in turn, update a treatment plan in accordance with the updated positions such that changes in the volume and positions of the one or more medical instruments are accounted for in the updated plan.
摘要翻译：用于医疗器械的动态定位的系统包括：超声成像系统（110），被配置为对部署了一个或多个医疗器械的体积进行成像。注册模块（136）登记一个或多个医疗器械的两个图像以计算两个图像之间的变换，两个图像在时间上分离。规划模块（142）被配置为具有基于变换而更新体积和一个或多个医疗仪器的位置，并且依次更新根据更新位置的治疗计划，使得体积和位置的变化一个或多个医疗器械在更新的计划中被计入。

9. 发明申请

WO2016059498A1 SYSTEM FOR REAL-TIME ORGAN SEGMENTATION AND TOOL NAVIGATION DURING TOOL INSERTION IN INTERVENTIONAL THERAPY AND METHOD OF OPEPERATION THEREOF 审中-公开
标题翻译：传统治疗工具插入期间实时机构分类和工具导航系统及其开发方法
公开(公告)号：WO2016059498A1
公开(公告)日：2016-04-21
申请号：PCT/IB2015/057466
申请日：2015-09-30
申请人： KONINKLIJKE PHILIPS N.V. , SUNNYBROOK HEALTH SCIENCES CENTRE
发明人： BHARAT, Shyam , DEHGHAN MARVAST, Ehsan , KRUECKER, Jochen , RAVI, Ananth , UHLEMANN, Falk , KUNG, Cynthia Ming-fu , AMTHOR, Thomas Erik
IPC分类号： A61B19/00
CPC分类号： G06T7/0012 , A61B5/4381 , A61B34/20 , A61B90/37 , A61B2034/2051 , A61B2090/364 , A61B2090/378 , G06T7/10 , G06T2207/10132
摘要： An interventional therapy system (100, 200, 300, 900) may include at least one controller (102, 202, 910) which may obtain a reference image dataset (540) of an object of interest (OOI); segment the reference image dataset to determine peripheral outlines (545) of the OOI in the plurality image slices; acquire a current image of the OOI (548) using an ultrasound probe (114, 224); select a peripheral outline (CBS, 545) of a selected image slice of the plurality of slices of the reference image dataset which is determined to correspond to the current image; and/or modify the selected peripheral outline of the image slice of the plurality of slices of the reference image dataset in accordance with at least one deformation vector (549).
摘要翻译：介入治疗系统（100,200,300,900）可以包括至少一个控制器（102,202,910），其可以获得感兴趣对象（50I）的参考图像数据集（540）; 分割参考图像数据集以确定多个图像切片中的OOI的外围轮廓（545）; 使用超声探头（114,224）获取所述OOI（548）的当前图像; 选择被确定为对应于当前图像的参考图像数据集的多个切片的选定图像切片的外围轮廓（CBS，545）; 和/或根据至少一个变形向量（549）修改参考图像数据集的多个切片的所选择的外围轮廓。

10. 发明申请

WO2015145300A2 QUALITY ASSURANCE AND DATA COORDINATION FOR ELECTROMAGNETIC TRACKING SYSTEMS 审中-公开
标题翻译：电磁跟踪系统的质量保证和数据协调
公开(公告)号：WO2015145300A2
公开(公告)日：2015-10-01
申请号：PCT/IB2015/051924
申请日：2015-03-17
申请人： KONINKLIJKE PHILIPS N.V.
发明人： BHARAT, Shyam , DEHGHAN MARVAST, Ehsan , KUNG, Cynthia Ming-fu , TAHMASEBI MARAGHOOSH, Amir Mohammad , DALAL, Sandeep M. , KRUECKER, Jochen , BONILLAS VACA, Antonio , STANTON, Douglas Allen
IPC分类号： A61B17/34
CPC分类号： A61B34/20 , A61B5/062 , A61B17/3403 , A61B2017/00274 , A61B2017/00725 , A61B2017/3411 , A61B2034/2051 , A61B2560/0223 , A61N5/1001 , A61N5/1027 , A61N5/1075 , A61N2005/1012
摘要： An electromagnetic ("EM") tracking configuration system employs an EM quality assurance ("EMQA") (30) and EM data coordination ("DC") system (70). For the EMQA system (30), an EM sensor block (40) includes EM sensor(s) (22) positioned and oriented to represent a simulated electromagnetic tracking of interventional tool(s) inserted through electromagnetic sensor block (40) into an anatomical region. As an EM field generator (20) generates an EM field (21) encircling EM sensor(s) (22), an EMQA workstation (50) tests an EM tracking accuracy of an insertion of the interventional tool(s) through the EM sensor block (40) into the anatomical region. For the EMDC system (70), as EM field generator (20) generates EM field (21) encircling a mechanical interaction of EM calibration tool(s) (80) with a grid (120) for guiding interventional tool(s) through gird (120) into an anatomical region, the electromagnetic data coordination workstation (90) establishes a coordination system for electromagnetically tracking an insertion of the interventional tool(s) through grid (120) into the anatomical region.
摘要翻译：电磁（“EM”）跟踪配置系统采用EM质量保证（“EMQA”）（30）和EM数据协调（“DC”）系统（70）。对于EMQA系统（30），EM传感器块（40）包括被定位和定向以表示对通过电磁传感器块（40）插入的介入工具进行模拟电磁跟踪的EM传感器（22），进入解剖学地区。当EM场发生器（20）产生包围EM传感器（22）的EM场（21）时，EMQA工作站（50）测试通过EM传感器插入介入工具的EM跟踪精度块（40）进入解剖区域。对于EMDC系统（70），当EM场发生器（20）产生包围EM校准工具（80）与网格（120）的机械相互作用的EM场（21），以引导介入工具穿过网格（120）进入解剖区域时，电磁数据协调工作站（90）建立用于电磁追踪介入工具穿过网格（120）插入解剖区域的协调系统。

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