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1. 发明申请

WO2011080700A1 METHOD FOR CALCULATING LOCAL SPECIFIC ENERGY ABSORPTION RATE (SAR) IN NUCLEAR MAGNETIC RESONANCE 审中-公开
标题翻译：计算核磁共振中局部特定能量吸收率（SAR）的方法
公开(公告)号：WO2011080700A1
公开(公告)日：2011-07-07
申请号：PCT/IB2010/056095
申请日：2010-12-28
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , VOIGT, Tobias, Ratko , KATSCHER, Ulrich , HOMANN, Hanno, Heyke
发明人： VOIGT, Tobias, Ratko , KATSCHER, Ulrich , HOMANN, Hanno, Heyke
IPC分类号： G01R33/28 , G01R33/56 , G01R33/58
CPC分类号： G01R33/288 , G01R33/246 , G01R33/443 , G01R33/543 , G01R33/546 , G01R33/5608
摘要： A method for calculating a local specific energy absorption rate (SAR) on basis of an electric parameter and the mass density of a segmented geometry of an object and a magnetic field vector distribution of a radio frequency (RF) antenna. The values of the electric parameter and the mass density are pre-determined values, while the magnetic field vector distribution is estimated by a magnetic field mapping method based on a magnetic resonance (MR) scan. The magnetic field mapping method based on a magnetic resonance scan can be a Bi mapping method. The invention also relates to a magnetic resonance system by means of which SAR calculation can be done in a relatively short period of time. The invention also relates to a computer program comprising instructions for calculating a local specific energy absorption rate (SAR) according to the above mentioned method. The SAR calculation used in the above mentioned method, system and program is done in the relatively short period of time and as such is practicable in a clinical setting.
摘要翻译：一种用于根据电参数和物体的分段几何形状的质量密度和射频（RF）天线的磁场矢量分布来计算局部比能吸收率（SAR）的方法。电参数和质量密度的值是预定值，而通过基于磁共振（MR）扫描的磁场映射方法来估计磁场矢量分布。基于磁共振扫描的磁场映射方法可以是Bi映射方法。本发明还涉及一种磁共振系统，通过该系统可以在相对较短的时间内进行SAR计算。本发明还涉及一种包括根据上述方法计算局部比能吸收率（SAR）的指令的计算机程序。上述方法，系统和程序中使用的SAR计算在相对较短的时间内完成，因此在临床环境中可行。

2. 发明申请

WO2011086512A1 ELECTRIC PROPERTIES TOMOGRAPHY IMAGING METHOD AND SYSTEM 审中-公开
标题翻译：电性质地图成像方法与系统
公开(公告)号：WO2011086512A1
公开(公告)日：2011-07-21
申请号：PCT/IB2011/050146
申请日：2011-01-13
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , VOIGT, Tobias, Ratko , KATSCHER, Ulrich , ROZIJN, Thomas, Hendrik , HARVEY, Paul, Royston , HOMANN, Hanno, Heyke , FINDEKLEE, Christian , HANSIS, Eberhard, Sebastian
发明人： VOIGT, Tobias, Ratko , KATSCHER, Ulrich , ROZIJN, Thomas, Hendrik , HARVEY, Paul, Royston , HOMANN, Hanno, Heyke , FINDEKLEE, Christian , HANSIS, Eberhard, Sebastian
IPC分类号： G01R33/48 , G01R33/14 , A61B5/055
CPC分类号： G01R33/48 , A61B5/0536 , A61B5/055 , G01R33/246 , G01R33/443
摘要： The invention relates to a magnetic resonance method of electric properties tomography imaging of an object, the method comprising: - applying an excitation RF field to the object via a coil at a first spatial coil position (402), acquiring resulting magnetic resonance signals via a receiving channel from the object, determining from the acquired magnetic resonance signals a first phase distribution and a first amplitude of a given magnetic field component of the excitation RF field of the coil at the first coil position (402), repeating these steps with a coil at a second different spatial coil position (404), to obtain a second phase distribution, determining a phase difference between the first and second phase distribution, - determining a first and a second complex permittivity of the object, the first complex permittivity comprising the first amplitude of the given magnetic field component and the second complex permittivity comprising the second amplitude of the given magnetic field component and the phase difference, - equating the first complex permittivity and the second complex permittivity for receiving a final equation and determining from the final equation a phase of the given magnetic field component for the first coil position (402).
摘要翻译：本发明涉及一种物体的电性能断层摄影成像的磁共振方法，该方法包括： - 通过第一空间线圈位置（402）上的线圈将激发RF场施加到物体上，通过经由从所述对象接收信道，从所获取的磁共振信号确定所述线圈在所述第一线圈位置（402）处的所述激励RF场的给定磁场分量的第一相位分布和第一振幅，用线圈重复这些步骤在第二不同空间线圈位置（404）处，以获得第二相位分布，确定所述第一和第二相位分布之间的相位差， - 确定所述对象的第一和第二复介电常数，所述第一复介电常数包括所述第一和第二相位分布给定磁场分量的振幅和包括给定磁f的第二振幅的第二复介电常数相位差， - 将第一复介电常数和第二复介电常数相等于接收最终方程，并从最终方程确定用于第一线圈位置（402）的给定磁场分量的相位。

3. 发明申请

WO2013024449A1 REDUCING THE RADIO-FREQUENCY TRANSMIT FIELD IN A PREDETERMINED VOLUME DURING MAGNETIC RESONANCE IMAGING 审中-公开
标题翻译：在磁共振成像期间减少预测体积中的无线电频率发射
公开(公告)号：WO2013024449A1
公开(公告)日：2013-02-21
申请号：PCT/IB2012/054163
申请日：2012-08-15
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , HOMANN, Hanno Heyke , GRAESSLIN, Ingmar , KATSCHER, Ulrich , VOIGT, Tobias Ratko , DÖSSEL, Olaf Helmut , SEITZ, Sebastian Alfred
发明人： HOMANN, Hanno Heyke , GRAESSLIN, Ingmar , KATSCHER, Ulrich , VOIGT, Tobias Ratko , DÖSSEL, Olaf Helmut , SEITZ, Sebastian Alfred
IPC分类号： G01R33/561 , G01R33/28
CPC分类号： G01R33/36 , G01R33/285 , G01R33/288 , G01R33/5612
摘要： Embodiments of the invention relate to a magnetic resonance imaging system (300) for acquiring magnetic resonance data (358) from a subject (318) that may comprise an electrically conductive object (e.g. an implant or a medical device). The magnetic resonance imaging system comprises a radio-frequency transmitter (314) for generating a radio-frequency transmit field for acquiring the magnetic resonance data using a radio-frequency antenna (310). The radio-frequency transmitter has multiple transmit channels. The radio-frequency antenna comprises multiple antenna elements (312) each adapted to connect to an antenna element. According to an embodiment of the invention, the amplitude and phase values of the RF transmit field of each of the transmit channels are selected such that the magnetic field generated by the RF antenna is minimized at the location of the electrically conductive object, thereby reducing RF heating of the object.
摘要翻译：本发明的实施例涉及一种用于从可包括导电物体（例如，植入物或医疗装置）的被摄体（318）获取磁共振数据（358）的磁共振成像系统（300）。磁共振成像系统包括用于使用射频天线（310）产生用于获取磁共振数据的射频发射场的射频发射机（314）。射频发射机具有多个发射信道。射频天线包括各自适于连接到天线元件的多个天线元件（312）。根据本发明的实施例，选择每个发射信道的RF发射场的幅度和相位值，使得由RF天线产生的磁场在导电物体的位置处最小化，从而减少RF 加热物体。

4. 发明申请

WO2009118702A3 FLIP ANGLE IMAGING WITH IMPROVED B1 MAPPING FOR MULTI-RF TRANSMIT SYSTEMS 审中-公开
公开(公告)号：WO2009118702A3
公开(公告)日：2009-10-01
申请号：PCT/IB2009/051258
申请日：2009-03-26
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , NEHRKE, Kay , BOERNERT, Peter , VOIGT, Tobias Ratko , KATSCHER, Ulrich
发明人： NEHRKE, Kay , BOERNERT, Peter , VOIGT, Tobias Ratko , KATSCHER, Ulrich
IPC分类号： G01R33/3415 , G01R33/565
摘要： A magnetic resonance method includes performing a plurality of magnetic resonance excitation operations each using a different sub-set of a set of radio frequency transmit coils (30), each sub-set including more than one radio frequency transmit coil, acquiring magnetic resonance data responsive to each said magnetic resonance excitation operation, and computing a B1 or flip angle map for each radio frequency transmit coil of the set of radio frequency transmit coils based on the acquired magnetic resonance data. A magnetic resonance method includes performing an actual flip angle mapping (AFI) sequence using a radio frequency transmit coil (32) with a ratio TR 1 : TR 2 of the TR times of the AFI sequence selected to be rational, acquiring magnetic resonance data responsive to said AFI sequence, and computing a B1 or flip angle map for the radio frequency transmit coil based on the acquired magnetic resonance data.

5. 发明申请

WO2009118688A1 DETERMINATION OF LOCAL SAR IN VIVO AND ELECTRICAL CONDUCTIVITY MAPPING 审中-公开
标题翻译：局部SAR在血液和电导率测绘中的测定
公开(公告)号：WO2009118688A1
公开(公告)日：2009-10-01
申请号：PCT/IB2009/051231
申请日：2009-03-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WEISS, Steffen , KATSCHER, Ulrich , VERNICKEL, Peter , VOIGT, Tobias Ratko , FINDEKLEE, Christian
发明人： WEISS, Steffen , KATSCHER, Ulrich , VERNICKEL, Peter , VOIGT, Tobias Ratko , FINDEKLEE, Christian
IPC分类号： G01R33/58 , A61B5/053
CPC分类号： G01R33/583 , A61B5/055 , G01R33/288
摘要： A magnetic resonance imaging apparatus produces calculations of local specific energy absorption rates (SAR) by calculating an electrical permittivity map of a subject. The electric permittivity is calculated by measuring the components of the B 1 field induced by a radio frequency (RF) coil (16). The H x and Hy components of the B 1 field can be directly measured. The H z component is measured by encoding it into the phase of the resonance signals. Alternately, H z can be calculated by solving Gauss's law for magnetism. H z can also be estimated by finding the z component of the electric field. In the specific case of a birdcage RF coil, H z can be estimated by using a model of the RF coil and a subject, a model of the RF coil alone, or setting H z to a constant.
摘要翻译：磁共振成像装置通过计算受试者的电容率图来产生局部比能吸收率（SAR）的计算。通过测量由射频（RF）线圈（16）感应的B1场的分量来计算电容率。可以直接测量B1场的Hx和Hy分量。通过对谐振信号的相位进行编码来测量Hz分量。或者，可以通过求解磁性的高斯定律来计算Hz。 Hz也可以通过找到电场的z分量来估计。在鸟笼RF线圈的具体情况下，可以通过使用RF线圈和对象的模型，单独的RF线圈的模型或将Hz设置为常数来估计Hz。

6. 发明申请

WO2010018504A2 METHOD AND MONITORING DEVICE FOR PERFORMING AN RF-SAFE MIT SCAN 审中-公开
标题翻译：用于执行RF安全麻省扫描的方法和监控装置
公开(公告)号：WO2010018504A2
公开(公告)日：2010-02-18
申请号：PCT/IB2009/053453
申请日：2009-08-07
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VERNICKEL, Peter , MAZURKEWITZ, Peter , WIRTZ, Daniel , LEUSSLER, Christoph , KATSCHER, Ulrich , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH
发明人： VERNICKEL, Peter , MAZURKEWITZ, Peter , WIRTZ, Daniel , LEUSSLER, Christoph , KATSCHER, Ulrich
IPC分类号： A61B5/05 , G01V3/10
CPC分类号： A61B5/0536 , A61B5/0522
摘要： A method and a monitoring device for performing an RF-safe MIT scan is disclosed in which it is prevented that an RF exposure, especially a specific absorption rate (SAR), imposed on an examination object, especially a patient, exceeds certain limit values during a magnetic induction tomography (MIT) scan. This is achieved on the one hand by an RF simulation method for simulating intended MIT operating parameters and calculating a resulting RF exposure of the object, and on the other hand by a monitoring device for monitoring the RF power which is applied to the object.
摘要翻译：公开了用于执行RF安全MIT扫描的方法和监视装置，其中防止施加在检查对象，特别是患者上的RF暴露，特别是特定吸收率（SAR）超过某些限制值磁感应断层扫描（MIT）扫描。这一方面通过用于模拟预期的MIT操作参数并计算所得到的对象的RF曝光的RF模拟方法，另一方面由用于监视施加到对象的RF功率的监视装置来实现。

7. 发明申请

WO2006067727A2 MAGNETIC RESONANCE IMAGING SYSTEM AND METHOD 审中-公开
标题翻译：磁共振成像系统及方法
公开(公告)号：WO2006067727A2
公开(公告)日：2006-06-29
申请号：PCT/IB2005/054312
申请日：2005-12-19
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KATSCHER, Ulrich , FINDEKLEE, Christian , VERNICKEL, Peter , LEUSSLER, Christoph
发明人： KATSCHER, Ulrich , FINDEKLEE, Christian , VERNICKEL, Peter , LEUSSLER, Christoph
CPC分类号： G01R33/3607 , G01R33/5611
摘要： The present invention relates to a magnetic resonance imaging system (1) comprising a plurality of RF coils (4) forming a multi-coil array and furthermore to a magnetic resonance imaging method for such a system. In order to provide an MR imaging system and method in which a desired excitation pattern is achieved in a simple way, it is suggested to utilize an analytical procedure how to combine the single coil elements to obtain the most homogeneous Bl excitation possible with a given coil array. In other words, the homogeneity of the Bl field is improved in a very simple way. The sensitivity of each RF coil (4) of the coil array is scaled or weighted by a complex factor, i.e. phase and amplitude of each coil drive signal is adjusted accordingly. These complex factors are determined analytically utilizing the sensitivities S (8) of the coil elements (4) and the desired excitation pattern P (IO, 11). The invention allows an optimized control of the field distribution (RF shimming) for arbitrary RF coil arrays. With the invention a fast and easy independent phase and amplitude control of the coil elements (4) is provided for reducing body- induced RF non- uniformities, which appear in high field MR systems.
摘要翻译：本发明涉及包括形成多线圈阵列的多个RF线圈（4）以及此类系统的磁共振成像方法的磁共振成像系统（1）。为了提供其中以简单的方式实现期望的激励模式的MR成像系统和方法，建议使用如何组合单个线圈元件以获得可用于给定线圈的最均匀的B1激励的分析程序阵列。换句话说，Bl场的均匀性以非常简单的方式得到改善。线圈阵列的每个RF线圈（4）的灵敏度被复合因子缩放或加权，即相应地调整每个线圈驱动信号的相位和幅度。利用线圈元件（4）的灵敏度S（8）和期望的激励模式P（IO，11）来分析地确定这些复杂因素。本发明允许对任意RF线圈阵列的场分布（RF匀场）的优化控制。利用本发明，提供了线圈元件（4）的快速且容易的独立相位和幅度控制，用于减少出现在高场MR系统中的体引起的RF非均匀性。

8. 发明申请

WO2011086477A1 THERAPEUTIC APPARATUS 审中-公开
标题翻译：治疗设备
公开(公告)号：WO2011086477A1
公开(公告)日：2011-07-21
申请号：PCT/IB2011/050038
申请日：2011-01-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KATSCHER, Ulrich , LIPS, Oliver , FINDEKLEE, Christian , LEUSSLER, Christoph , NEHRKE, Kay , WIRTZ, Daniel , OVERWEG, Johannes, Adrianus
发明人： KATSCHER, Ulrich , LIPS, Oliver , FINDEKLEE, Christian , LEUSSLER, Christoph , NEHRKE, Kay , WIRTZ, Daniel , OVERWEG, Johannes, Adrianus
IPC分类号： A61N7/02 , A61N1/40 , A61N5/10 , A61B17/00 , A61B19/00
CPC分类号： A61N5/1064 , A61B2017/00084 , A61B2090/374 , A61N1/403 , A61N5/10 , A61N5/1084 , A61N7/00 , A61N7/02 , A61N2005/007 , A61N2005/1055 , G01R33/4804 , G01R33/4808
摘要： The invention provides for a therapeutic apparatus comprising a tissue heating system (302, 480, 482). The therapeutic apparatus further comprises a magnetic resonance imaging system (300) for acquiring magnetic resonance thermometry data (366) from nuclei of a subject (318) located within an imaging volume (330). The therapeutic apparatus further comprises a radiation therapy system (304, 592) for irradiating an irradiation volume (316, 516) of the subject, wherein the irradiation volume is within the imaging volume. The therapeutic apparatus further comprises a controller (354) for controlling the therapeutic apparatus. The controller is adapted for acquiring (100, 210) magnetic resonance thermometry data repeatedly using the magnetic resonance imaging system. The controller is adapted for heating (102, 208) at least the irradiation volume using the tissue heating system. The heating is controlled using the magnetic resonance thermometry data. The controller is adapted for irradiating (104, 208) the irradiation volume.
摘要翻译：本发明提供一种包括组织加热系统（302,480,482）的治疗设备。治疗装置还包括用于从位于成像体积（330）内的对象（318）的核获取磁共振测温数据（366）的磁共振成像系统（300）。治疗装置还包括用于照射受试者的照射体积（316,516）的放射治疗系统（304,592），其中照射体积在成像体积内。治疗装置还包括用于控制治疗仪的控制器（354）。控制器适于使用磁共振成像系统重复地获取（100,210）磁共振测温数据。控制器适于使用组织加热系统加热（102,208）至少照射体积。使用磁共振测温数据来控制加热。控制器适于照射（104,208）照射体积。

9. 发明申请

WO2011015983A1 APPARATUS AND METHOD FOR DETERMINING AT LEAST ONE ELECTROMAGNETIC QUANTITY 审中-公开
标题翻译：用于确定最小一个电磁数量的装置和方法
公开(公告)号：WO2011015983A1
公开(公告)日：2011-02-10
申请号：PCT/IB2010/053497
申请日：2010-08-02
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , VERNICKEL, Peter , KATSCHER, Ulrich , GLEICH, Bernhard , RAHMER, Jürgen, Erwin
发明人： VERNICKEL, Peter , KATSCHER, Ulrich , GLEICH, Bernhard , RAHMER, Jürgen, Erwin
IPC分类号： A61B5/05
CPC分类号： A61B5/05 , A61B5/0515 , A61B5/7221 , A61B2562/0223
摘要： The present invention relates to an apparatus (100) for determining at least one electromagnetic quantity characterizing an electromagnetic property of an object, in particular a human body, wherein said object contains magnetic particles. The apparatus (100) applying the known principle of Magnetic Particle Imaging (MPI) comprises selection means for generating a magnetic selection field (50) having the known field pattern showing a field free point (FFP), drive means for changing the position in space of the FFP by means of a magnetic drive field, receiving means for acquiring detection signals depending on the magnetization of the magnetic particles within a field of view (28) and a reconstruction unit (152) for reconstructing a particle distribution quantity depending on the detection signals. The apparatus (100) further comprises a control unit (150) for controlling the receiving means for acquiring a first set of detection signals corresponding to a first drive field frequency and a second set of detection signals corresponding to a second drive field frequency, with both drive field frequencies differing from each other. The control unit (15) further controls the reconstruction unit (152) for reconstructing a first particle distribution quantity depending on the first set of detection signals and a second particle distribution quantity depending on the second set of detection signals. The apparatus (100) further comprises a determination unit (160) for determining the electromagnetic quantity depending on the first and second particle distribution quantity. The present invention further relates to a corresponding method as well as to a computer program.
摘要翻译：本发明涉及一种用于确定表征物体特别是人体的电磁特性的至少一个电磁量的装置（100），其中所述物体包含磁性颗粒。应用已知的磁性粒子成像原理（MPI）的装置（100）包括用于产生具有示出场自由点（FFP）的已知场图案的磁选择场（50）的选择装置，用于改变空间位置的驱动装置通过磁驱动场的FFP的接收装置，用于根据视野内的磁性粒子的磁化获取检测信号的接收装置（28）和用于根据检测重建粒子分布量的重建单元（152）信号。所述设备（100）还包括控制单元（150），用于控制所述接收装置，用于获取对应于第一驱动场频率的第一组检测信号和对应于第二驱动场频率的第二组检测信号，驱动场频率彼此不同。控制单元（15）进一步控制重建单元（152），用于根据第一组检测信号重建第一粒子分布量，并根据第二组检测信号控制第二粒子分布量。该设备（100）还包括用于根据第一和第二粒子分布量来确定电磁量的确定单元（160）。本发明还涉及相应的方法以及计算机程序。

10. 发明申请

WO2010032193A1 RF SHIMMING WITH RF POWER REGULARIZATION USING A MULTI-CHANNEL RF TRANSMIT SYSTEM FOR MRI 审中-公开
标题翻译：使用多通道射频发射系统进行射频功率定量的射频成像
公开(公告)号：WO2010032193A1
公开(公告)日：2010-03-25
申请号：PCT/IB2009/054014
申请日：2009-09-15
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KATSCHER, Ulrich , GRAESSLIN, Ingmar
发明人： KATSCHER, Ulrich , GRAESSLIN, Ingmar
IPC分类号： G01R33/3415
CPC分类号： G01R33/3415 , G01R33/288 , G01R33/5612 , G01R33/5659
摘要： A magnetic resonance system comprises: a magnetic resonance scanner (12) including a multi-channel RF transmit system (32, 34); an RF shimming processor (50) configured to compute complex amplitude values for operative channels of the multi-channel RF transmit system based on a figure-of-merit (70) comprising a weighted combination of a B1 uniformity measure and a total power measure; and an RF transmit sub-system (30) configured to drive the multi-channel RF transmit system to excite magnetic resonance using the complex amplitude values computed by the RF shimming processor for the operative channels of the multi-channel RF transmit system.
摘要翻译：磁共振系统包括：包括多通道RF发射系统（32,34）的磁共振扫描仪（12）; RF匀场处理器（50），被配置为基于包括B1均匀度测量和总功率测量的加权组合的品质因数（70）来计算所述多通道RF发射系统的操作信道的复振幅值; 以及RF发射子系统（30），其被配置为使用由所述RF匀场处理器为所述多声道RF发射系统的操作信道计算的复振幅值来驱动所述多声道RF发射系统以激励磁共振。

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