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2. 发明申请

WO2009053889A3 MANIPULATION OF PARTICLES BY DIELECTROPHORESIS 审中-公开
标题翻译：电泳法处理颗粒
公开(公告)号：WO2009053889A3
公开(公告)日：2009-10-15
申请号：PCT/IB2008054305
申请日：2008-10-20
申请人： KONINKL PHILIPS ELECTRONICS NV , COLLINS PAUL L
发明人： COLLINS PAUL L
IPC分类号： B03C5/02
CPC分类号： B03C5/028
摘要： The present invention provides a dielectrophoretic device for manipulation of at least a first and a second type of particles (1, 2) present in a sample fluid. The device comprises at least one array (3) of electrodes (4), the array (3) comprising at least a plurality of electrodes (4) in a first region (5) and a plurality of electrodes (4) in a second region (6), driving means (32) for driving the electrodes (4) of the first and second region (5, 6) of the array (3) to generate a travelling wave dielectrophoretic force to be exerted on the at least first and second types of particles (1, 2), and a controller (30) for controlling the driving means (32), the controller (30) being adapted for first driving the electrodes (4) of the first and second region (5, 6) with a same driving signal and subsequently changing the driving signal to electrodes (4) of at least one of the first and second region (5, 6) so as to separate at least some particles (1) of the first type from the particles (2) of the second type. The present invention also provides a method for forming such a dielectrophoretic device, a method for manipulation of at least a first and a second type of particles (1, 2) present in a sample fluid and a controller (30) for controlled driving of electrodes (4) of such a dielectrophoretic device.
摘要翻译：本发明提供了用于操纵存在于样品流体中的至少第一和第二类型颗粒（1,2）的介电泳装置。该装置包括至少一个电极（4）阵列（3），阵列（3）包括第一区域（5）中的至少多个电极（4）和第二区域中的多个电极（4）（6）;驱动装置（32），用于驱动阵列（3）的第一和第二区域（5,6）的电极（4），以产生行波介电泳力，以施加在至少第一和第二（1,2）的类型和用于控制驱动装置（32）的控制器（30），控制器（30）适于首先驱动第一和第二区域（5,6）的电极（4）利用相同的驱动信号并且随后改变驱动信号到第一和第二区域（5,6）中的至少一个的电极（4），以便将至少一些第一类型的颗粒（1）与颗粒（ 2）的第二种类型。本发明还提供了一种用于形成这种介电泳装置的方法，一种用于操作存在于样本流体中的至少第一和第二类型颗粒（1,2）的方法以及用于受控驱动电极的控制器（30）（4）这种介电泳装置。

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