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    • 6. 发明申请
    • ULTRASONIC TREATMENT CHAMBER FOR PREPARING ANTIMICROBIAL FORMULATIONS
    • 用于制备抗微生物制剂的超声处理室
    • WO2009083909A2
    • 2009-07-09
    • PCT/IB2008055517
    • 2008-12-23
    • KIMBERLY CLARK COJANSSEN ROBERT ALLENWENZEL SCOTT WKOENIG DAVID WILLIAMEHLERT THOMAS DAVIDZHUANG SHIMINGAHLES JOHN GLENRASMUSSEN PAUL WARRENROFFERS STEVE
    • JANSSEN ROBERT ALLENWENZEL SCOTT WKOENIG DAVID WILLIAMEHLERT THOMAS DAVIDZHUANG SHIMINGAHLES JOHN GLENRASMUSSEN PAUL WARRENROFFERS STEVE
    • B01F11/0258B01F2215/0009B01F2215/045B01F2215/0454
    • An ultrasonic mixing system having a treatment chamber in which antimicrobial agents, particularly, hydrophobic antimicrobial agents, can be mixed with one or more formulations is disclosed. Specifically, the treatment chamber has an elongate housing through which a formulation and antimicrobial agents flow longitudinally from a first inlet port and a second inlet port to an outlet port thereof. An elongate ultrasonic waveguide assembly extends within the housing and is operable at a predetermined ultrasonic frequency to ultrasonically energize the formulation and antimicrobial agents within the housing. An elongate ultrasonic horn of the waveguide assembly is disposed at least in part intermediate the inlet and outlet ports, and has a plurality of discrete agitating members in contact with and extending transversely outward from the horn intermediate the inlet and outlet ports in longitudinally spaced relationship with each other. The horn and agitating members are constructed and arranged for dynamic motion of the agitating members relative to the horn at the predetermined frequency and to operate in an ultrasonic cavitation mode of the agitating members corresponding to the predetermined frequency and the formulation and antimicrobial agents being mixed in the chamber.
    • 公开了一种具有处理室的超声波混合系统,其中抗微生物剂,特别是疏水性抗微生物剂可以与一种或多种制剂混合。 具体而言,处理室具有细长壳体,制剂和抗微生物剂通过该壳体纵向地从第一入口端口和第二入口端口流向其出口端口。 细长的超声波导组件在外壳内延伸并且可以预定的超声频率操作以超声地激励外壳内的制剂和抗微生物剂。 波导组件的细长超声波喇叭筒至少部分地设置在入口和出口端口的中间,并且具有多个分立的搅动构件,该喇叭状件与喇叭口接触并从喇叭口横向向外延伸,入口和出口之间以纵向间隔的关系与 彼此。 喇叭和搅动构件被构造和布置成用于搅动构件相对于喇叭以预定频率进行动态运动并且以与预定频率相对应的搅动构件的超声空化模式进行操作,并且制剂和抗微生物剂被混入 房间。
    • 8. 发明申请
    • ULTRASONIC TREATMENT CHAMBER FOR INCREASING THE SHELF LIFE OF FORMULATIONS
    • 超声波治疗室用于增加制剂寿命
    • WO2009083906A2
    • 2009-07-09
    • PCT/IB2008055514
    • 2008-12-23
    • KIMBERLY CLARK COKOENIG DAVID WILLIAMAHLES JOHN GLENEHLERT THOMAS DAVIDJANSSEN ROBERT ALLENRASMUSSEN PAUL WARRENROFFERS STEVEWENZEL SCOTT WZHUANG SHIMING
    • KOENIG DAVID WILLIAMAHLES JOHN GLENEHLERT THOMAS DAVIDJANSSEN ROBERT ALLENRASMUSSEN PAUL WARRENROFFERS STEVEWENZEL SCOTT WZHUANG SHIMING
    • B01D19/0094B01D19/0078
    • An ultrasonic treatment system having a treatment chamber for treating a formulation to increase the shelf life thereof. In one embodiment, the shelf life is produced by degassing the formulation using the treatment chamber. Specifically, the treatment chamber has an elongate housing through which a formulation flows longitudinally from an inlet port to a first outlet port and a second outlet port thereof. An elongate ultrasonic waveguide assembly extends within the housing and is operable at a predetermined ultrasonic frequency to ultrasonically energize the formulation within the housing. An elongate ultrasonic horn of the waveguide assembly is disposed at least in part intermediate the inlet and outlet ports, and has a plurality of discrete agitating members in contact with and extending transversely outward from the horn intermediate the inlet and outlet ports in longitudinally spaced relationship with each other. The horn and agitating members are constructed and arranged for dynamic motion of the agitating members relative to the horn at the predetermined frequency and to operate in an ultrasonic cavitation mode of the agitating members corresponding to the predetermined frequency and the formulation being treated in the chamber.
    • 一种超声处理系统,其具有用于处理制剂以增加其保质期的处理室。 在一个实施方案中,通过使用处理室对制剂进行脱气而产生保质期。 具体地说,处理室具有细长的外壳,制剂通过该外壳纵向从入口端口流向第一出口和第二出口。 细长的超声波波导组件在壳体内延伸并且可以预定的超声频率操作以超声波地激励壳体内的配方。 波导组件的细长的超声波喇叭至少部分地设置在入口和出口的中间,并且具有多个离散的搅拌构件,其与入口和出口端口处的喇叭的横向外部接触并向外延伸,与纵向间隔开的关系 彼此。 喇叭和搅拌构件被构造和布置成用于以预定频率相对于喇叭的动态运动,并且以对应于预定频率的搅拌构件的超声空化模式和在腔室中处理的配方进行操作。