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1. 发明申请

WO2010086829A3 ABSORBENT ARTICLES CONTAINING A MULTIFUNCTIONAL GEL 审中-公开
标题翻译：含有多功能凝胶的吸收制品
公开(公告)号：WO2010086829A3
公开(公告)日：2010-12-29
申请号：PCT/IB2010050416
申请日：2010-01-29
申请人： KIMBERLY CLARK CO , YAHIAOUI ALI , KRAUTKRAMER CANDACE DYAN , LATIMER MARGARET G , LINTON JACK NELSON , ROSS RUSSELL F , DENNIS MELISSA JEAN , WOLTMAN GARRY ROLAND
发明人： YAHIAOUI ALI , KRAUTKRAMER CANDACE DYAN , LATIMER MARGARET G , LINTON JACK NELSON , ROSS RUSSELL F , DENNIS MELISSA JEAN , WOLTMAN GARRY ROLAND
IPC分类号： A61F13/511 , A61F13/53 , A61F13/58 , A61L15/60
CPC分类号： A61L15/58 , A61F13/82 , A61F2013/530481 , A61L15/60
摘要： Improved skin-adhesive compositions for bonding a substrate, such as an absorbent article, to skin are disclosed. More particularly, the skin-adhesive composition has an improved, yet gentle, adhesion to the skin of a user, while maintaining strong, effective bonding to various inanimate, non-skin substrates. In one embodiment, the skin- adhesive composition can provide one or more skin benefit agents to the user. The skin-adhesive composition may be applied to an absorbent article, such as a panty-liner, sanitary napkin, or an incontinence article, for directly adhering the article to the skin of a user.
摘要翻译：公开了用于将基底（例如吸收性物品）粘合到皮肤上的改进的皮肤粘合剂组合物。更具体地说，所述皮肤 - 粘合剂组合物对使用者的皮肤具有改善的但温和的粘附性，同时保持与各种无生命的非皮肤基质的强有力的结合。在一个实施方案中，该皮肤粘合剂组合物可以向使用者提供一种或多种皮肤有益剂。该皮肤粘合剂组合物可以用于吸收性物品，例如卫生护垫，卫生巾或失禁用品，用于直接将物品粘附到使用者的皮肤上。

2. 发明申请

WO2011080649A3 PUNCTURE RESISTANT FABRIC 审中-公开
标题翻译：防刺穿织物
公开(公告)号：WO2011080649A3
公开(公告)日：2011-11-17
申请号：PCT/IB2010055883
申请日：2010-12-16
申请人： KIMBERLY CLARK CO , MACDONALD JOHN GAVIN , ROSS RUSSELL F , RYU JINHO
发明人： MACDONALD JOHN GAVIN , ROSS RUSSELL F , RYU JINHO
IPC分类号： D06M11/78 , D06M11/45 , D06M13/12
CPC分类号： D06M11/45 , D06M11/46 , D06M11/79 , D06M13/123 , D06M13/507 , D06M13/513 , D06M15/39 , D06M15/423 , D06M15/643 , D06M15/6436 , D06M23/08 , Y10T442/2615 , Y10T442/273 , Y10T442/2803 , Y10T442/603
摘要： The present invention is generally directed to a nonwoven fabric having a plurality of coated fibers, the coating including silane and dialdehyde, and, in certain embodiments, further including particles.
摘要翻译：本发明总体上涉及具有多根涂覆纤维的非织造织物，所述涂层包括硅烷和二醛，并且在某些实施方案中，还包括颗粒。

3. 发明申请

WO2011080678A2 WEARABLE ARTICLE THAT STIFFENS UPON SUDDEN FORCE 审中-公开
标题翻译：令人震惊的文章，强化了对强大的力量
公开(公告)号：WO2011080678A2
公开(公告)日：2011-07-07
申请号：PCT/IB2010056034
申请日：2010-12-22
申请人： KIMBERLY CLARK CO , SAWYER LAWRENCE , JOHNSON ERIC D , MCMANUS JAMES D , MACDONALD JOHN GAVIN , ROSS RUSSELL F
发明人： SAWYER LAWRENCE , JOHNSON ERIC D , MCMANUS JAMES D , MACDONALD JOHN GAVIN , ROSS RUSSELL F
IPC分类号： A61F5/058 , D06M10/00 , D06M11/01 , D06M11/78 , D06M13/12
CPC分类号： A61F13/04 , A61L15/12 , D06M13/123 , D06M13/513 , D06M23/08
摘要： A wearable article made from a nonwoven fabric that includes a plurality of coated fibers. The coated fibers have an exterior surface and a coating composition on at least a portion of the exterior surface. The coating composition includes an aminofunctionalized silane and a dialdehyde, where the weight percent of the dialdehyde in the coating composition is greater than the weight percent of the silane in the coating composition. The wearable article can be a wrap, brace, support, compression hosiery, bandage or compress. When worn, the wearable article is initially flexible but becomes rigid and stiff when the coated fibers experience a sudden force or impact. The wearable article does not include a fluid.
摘要翻译：一种由包括多根被覆纤维的无纺布制成的可穿戴物品。涂覆的纤维在外表面的至少一部分上具有外表面和涂料组合物。涂料组合物包括氨基官能化硅烷和二醛，其中涂料组合物中二醛的重量百分比大于涂料组合物中硅烷的重量百分数。可穿戴物品可以是包裹，支撑，支撑，压缩袜，绷带或压缩。当穿着时，可穿戴物品最初是柔性的，但是当涂覆的纤维经受突然的力或冲击时变得刚性和刚性。可穿戴物品不包括流体。

4. 发明申请

WO2012090103A3 THERMOPLASTIC COMPOSITIONS FOR SHEET MATERIALS HAVING IMPROVED TENSILE PROPERTIES 审中-公开
标题翻译：具有改进拉伸性能的材料的热塑性组合物
公开(公告)号：WO2012090103A3
公开(公告)日：2012-11-15
申请号：PCT/IB2011055559
申请日：2011-12-08
申请人： KIMBERLY CLARK CO , ROSS RUSSELL F , NG WING-CHAK , MACDONALD JOHN GAVIN
发明人： ROSS RUSSELL F , NG WING-CHAK , MACDONALD JOHN GAVIN
IPC分类号： C08L23/00 , C08J5/18 , C08K3/00 , C08K7/00 , D01F6/04
CPC分类号： C08L23/10 , B82Y30/00 , C08L2205/02
摘要： Disclosed is a thermoplastic composition suitable for forming sheet materials with improved tensile properties. The thermoplastic composition includes from about 1 to about 98 weight percent of a fiber-forming or film-forming polymer, from about 1 to about 98 weight percent of a low melt flow rate polymer having a melt flow rate less than 20 grams per 10 minutes, and from about 0.1 to about 10 weight percent of nanoparticles. The nanoparticles may be cylindrical nanoparticles having an average aspect ratio greater than about 1 and less than about 500.
摘要翻译：公开了一种适合于形成具有改善的拉伸性能的片材的热塑性组合物。热塑性组合物包括约1至约98重量％的成纤或成膜聚合物，约1至约98重量％的熔体流动速率小于20克/ 10分钟的低熔体流动速率聚合物，和约0.1至约10重量％的纳米颗粒。纳米颗粒可以是具有大于约1且小于约500的平均纵横比的圆柱形纳米颗粒。

5. 发明申请

WO2012117302A3 TRANSDERMAL PATCH CONTAINING MICRONEEDLES 审中-公开
标题翻译：包含麦克风的透皮配对
公开(公告)号：WO2012117302A3
公开(公告)日：2012-11-08
申请号：PCT/IB2012050203
申请日：2012-01-16
申请人： KIMBERLY CLARK CO , ROSS RUSSELL F
发明人： ROSS RUSSELL F
IPC分类号： A61M37/00 , A61M35/00
CPC分类号： A61M5/14248 , A61K9/0021 , A61M37/0015 , A61M2037/0023 , A61M2037/003 , A61M2037/0038 , A61M2037/0061
摘要： A transdermal patch that can easily deliver a controlled volume of a fluidic drug compound to the skin is provided. More particularly, the patch contains a microneedle assembly that is configured to be placed in fluid communication with a drug delivery assembly. The microneedle assembly contains a support and a plurality of microneedles that extend outwardly from the support. The microneedles are formed with one or more channels of a certain dimension such that passive capillary flow drives the flow of the drug compound. The drug delivery system contains a reservoir for the drug compound that is in fluid communication with -a rate control membrane that helps control the flow rate of the drug compound by modulating its pressure downstream from the reservoir. A release member is also positioned adjacent to the microneedle and drug delivery assemblies. Prior to use, the release member acts as a barrier to the flow of the drug compound and thus inhibits premature leakage. In this manner, the patch can initially be provided in an "inactive" configuration in which the drug compound is securely retained. When it is desired to release the drug compound, the patch can simply be activated by at least partially separating the release member from the drug delivery and microneedle assemblies.
摘要翻译：提供了可以容易地将受控体积的流体药物化合物递送至皮肤的透皮贴剂。更具体地，补片包含配置成与药物输送组件流体连通的微针组件。微针组件包含支撑件和从支撑件向外延伸的多个微针。微针形成有一个或多个具有一定尺寸的通道，使得被动毛细管流驱动药物化合物的流动。药物递送系统包含与速率控制膜流体连通的药物化合物的储存器，其通过调节其从储存器下游的压力来帮助控制药物化合物的流速。释放构件也邻近微针和药物输送组件定位。在使用之前，释放构件作为药物化合物流动的屏障，从而抑制过早的渗漏。以这种方式，补片最初可以以其中药物化合物被牢固地保持的“无活性”构型提供。当需要释放药物化合物时，可以通过至少部分地将释放构件与药物递送和微针组件分离来简单地活化贴剂。

6. 发明申请

WO2015168219A8 CONTROLLER PORTION OF TRANSDERMAL DRUG DELIVERY APPARATUS AND METHODS 审中-公开
标题翻译：超导药物输送装置和方法的控制部分
公开(公告)号：WO2015168219A8
公开(公告)日：2016-12-01
申请号：PCT/US2015028164
申请日：2015-04-29
申请人： KIMBERLY CLARK CO
发明人： BAKER ANDREW T , GADSBY ELIZABETH DEIBLER , ROSS RUSSELL F , HAGAN LUKE
IPC分类号： A61M37/00
CPC分类号： A61M37/00 , A61M2037/0023
摘要： A controller, which may be used in a transdermal drug delivery apparatus, includes a housing, a pushing mechanism mounted for moving relative to the housing, a force provider positioned between the housing and the pushing mechanism for moving the pushing mechanism relative to the housing, and a latching mechanism for selectively restricting and allowing relative movement between the housing and the pushing mechanism. The pushing mechanism may be configured for pushing against a reservoir of the transdermal drug delivery apparatus. The latching mechanism may include flexible arms extending between the opposite ends of the latching mechanism, and the latching mechanism may be configured so that the arms release the pushing mechanism in response to the opposite ends being forced toward one another.
摘要翻译：可用于透皮药物输送装置的控制器包括壳体，安装成相对于壳体移动的推动机构，位于壳体和推动机构之间的力提供件，用于相对于壳体移动推动机构，以及用于选择性地限制和允许壳体和推动机构之间的相对运动的闭锁机构。推动机构可以被配置为推动透皮药物递送装置的储存器。闩锁机构可以包括在闩锁机构的相对端部之间延伸的柔性臂，并且闩锁机构可以被构造成使得臂相对于相对的端部被迫朝向彼此而释放推动机构。

7. 发明申请

WO2011070457A3 TRANSDERMAL DELIVERY DEVICE 审中-公开
标题翻译：超传送装置
公开(公告)号：WO2011070457A3
公开(公告)日：2011-11-17
申请号：PCT/IB2010055093
申请日：2010-11-09
申请人： KIMBERLY CLARK CO , ROSS RUSSELL F
发明人： ROSS RUSSELL F
IPC分类号： A61M37/00 , A61M5/158
CPC分类号： A61M37/0015 , A61M2037/0023 , A61M2037/0038
摘要： The present invention relates generally to a transdermal delivery device which is suitable for the transdermal delivery or removal of substances, and in particular relates to a transdermal delivery device having a support and a plurality of microneedles projecting outwardly from the support, at least one microneedle including a channel positioned on the exterior surface which aligns with at least one aperture being formed in the support.
摘要翻译：本发明一般涉及适合于透皮递送或去除物质的透皮递送装置，并且具体涉及一种透皮递送装置，其具有支撑体和从支撑体向外突出的多个微针，至少一个微针包括定位在外表面上的通道，其与形成在支撑件中的至少一个孔对准。

8. 发明公开

EP3137152A4 DRAPED MICRONEEDLE ARRAY 有权转让
公开(公告)号：EP3137152A4
公开(公告)日：2018-03-14
申请号：EP15785673
申请日：2015-04-29
申请人： KIMBERLY CLARK CO
发明人： BAKER ANDREW T , GADSBY ELIZABETH DEIBLER , ROSS RUSSELL F
IPC分类号： A61M37/00 , A61B5/15 , B29C35/08 , B29L31/00
CPC分类号： A61M37/0015 , A61B5/150022 , A61B5/150435 , A61B5/150984 , A61M2037/0038 , A61M2037/0053 , B29C35/0805 , B29L2031/753
摘要： The configuration of an elongate aperture in a membrane draped over a microneedle assembly may be controlled by controlling the manner in which the aperture is formed and/or by controlling the manner in which the membrane is draped. At least a portion of the membrane may be spaced apart from a microneedle so that a gap is defined between the membrane and the microneedle. The gap may be configured for at least partially controlling the formation of the elongate aperture. The shape of the gap may optionally be at least partially defined by a pleat in the membrane. Any pleats may be aligned in a predetermined manner. The elongate aperture may be formed by a piercing member that is passed through a hole in the microneedle assembly prior to piercing the membrane. The piercing member may be a laser beam.

9. 发明公开

EP3137150A4 RECEPTACLE PORTION OF TRANSDERMAL DRUG DELIVERY APPARATUS AND METHODS 有权转让
公开(公告)号：EP3137150A4
公开(公告)日：2017-12-13
申请号：EP15785287
申请日：2015-04-29
申请人： KIMBERLY CLARK CO
发明人： BAKER ANDREW T , GADSBY ELIZABETH DEIBLER , ROSS RUSSELL F , HAGAN LUKE
IPC分类号： A61M37/00 , A61M35/00
CPC分类号： A61M37/0015 , A61M2037/0023
摘要： A receptacle, which may be suitable for use as a portion of a transdermal drug delivery apparatus, may include a housing for being fastened to the user, a force provider that is elastic, at least one deformable component, and a microneedle assembly movably mounted to the housing for moving inwardly and outwardly relative to the housing. The force provider may be positioned between the housing and the microneedle assembly for forcing the microneedle assembly outwardly relative to the housing and against the skin of the user. The at least one deformable component may be connected between the microneedle assembly and the housing for both allowing relative movement between the microneedle assembly and the housing, and at least partially restricting the microneedle assembly from falling away from the housing. An arresting member may be positioned between the housing and the microneedle assembly for restricting any movement of at least tips of microneedles of the microneedle assembly into an interior of the housing.

10. 发明公开

EP2961469A4 DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：EP2961469A4
公开(公告)日：2016-10-26
申请号：EP14756540
申请日：2014-02-28
申请人： KIMBERLY CLARK CO
发明人： BAKER ANDREW , ROSS RUSSELL F , HAGAN LUKE
IPC分类号： A61M37/00
CPC分类号： A61M37/0015 , A61M2037/0023 , A61M2037/003 , A61M2037/0038 , A61M2037/0061 , A61M2210/04
摘要： A drug delivery device is disclosed that may include a skin penetrating assembly having a support defining an upper surface and a lower surface. The skin penetrating assembly may also include a plurality of skin penetrating members extending outwardly from the lower surface. Each skin penetrating member may define a channel for receiving a drug formulation. In addition, the device may include a reservoir positioned adjacent to the upper surface of the support for initially retaining the drug formulation. The reservoir may include a top surface and a bottom surface and may define a plurality of passages extending between the top and bottom surfaces. The passages may be configured such that the drug formulation is retained within the passages against gravity.

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