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1. 发明申请

WO2007118209A3 APPARATUS AND METHOD FOR RAPID DETECTION OF ANALYTES 审中-公开
标题翻译：用于快速检测分析仪的装置和方法
公开(公告)号：WO2007118209A3
公开(公告)日：2008-09-04
申请号：PCT/US2007066172
申请日：2007-04-06
申请人： KIM LAB , JOE IKRO , KIM MYUNG L , PARK HOSHIN , MORLOK RYAN , SHINN ALAN , FAN CHIKO , ELIAS ELIAS
发明人： JOE IKRO , KIM MYUNG L , PARK HOSHIN , MORLOK RYAN , SHINN ALAN , FAN CHIKO , ELIAS ELIAS
IPC分类号： C12M1/34 , C12M3/00
CPC分类号： G01N33/569 , G01N21/6428 , G01N21/645 , G01N33/5308 , G01N2201/0221
摘要： The system of the present disclosure is a system for real time, rapid detection of a targetanalyte in a liquid sample, the system comprising: a sample holder (30) to hold the liquid sample wherein the sample holder is adapted and disposed for rotational motion; a optical source (22) to provide an excitation light beam to excite a fluorescence marker in the sample to emit an emission light; an objective lens (35) to focus the excitation light beam in the sample wherein at least a portion of the optical source is adapted and disposed for translational motion whereby the excitation light beam translates along at least a portion of the sample holder; a detector (70) to record the intensity of the emission light over the period of time; and a member (74) to calculate the number of cells or microorganisms in the sample from the recorded intensity of the emission light over the period of time.
摘要翻译：本公开的系统是用于实时，快速检测液体样品中的目标分析物的系统，该系统包括：样品保持器（30），用于保持液体样品，其中样品保持器适于并设置用于旋转运动; 提供激发光束以激发样品中的荧光标记物以发射发射光的光源（22）; 物镜（35），用于将激发光束聚焦在样品中，其中光源的至少一部分适于并设置用于平移运动，由此激发光束沿着样品保持器的至少一部分平移; 检测器（70），用于在一段时间内记录发射光的强度; 以及成员（74），用于根据记录的发射光强度在一段时间内计算样品中的细胞数量或微生物数量。

2. 发明申请

WO2008005880A2 ANTIBODIES FOR NOROVIRUS 审中-公开
标题翻译： NOROVIRUS的抗体
公开(公告)号：WO2008005880A2
公开(公告)日：2008-01-10
申请号：PCT/US2007072559
申请日：2007-06-29
申请人： KIM LAB , FRYE JANE CATHERINE , PARK HOSHIN , KIM MYUNG L
发明人： FRYE JANE CATHERINE , PARK HOSHIN , KIM MYUNG L
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K2039/53 , A61K2039/55516 , A61K2039/6081 , C07K16/10 , C12N2770/16022 , C12N2770/16034 , G01N33/56983 , G01N2333/08 , Y10S435/975
摘要： Norovirus antigen peptides are described having an amino acid sequence selected from the group consisting of SEQ ID NOS: 1-16, or fragments thereof. Such peptides can be used in the preparation of antiviral therapies such as vaccines, methods of preparing antibodies to the antigen peptides, methods of using the peptides or the corresponding antibodies for detection of norovirus, and compositions of the peptides, DNA and/or antibodies. A kit for the detection of norovirus is also provided.
摘要翻译：描述了具有选自SEQ ID NOS：1-16的氨基酸序列的诺如病毒抗原肽或其片段。这些肽可用于制备抗病毒疗法，例如疫苗，制备抗原肽抗体的方法，使用该肽或相应抗体检测诺罗病毒的方法，以及肽，DNA和/或抗体的组成。还提供了检测诺如病毒的试剂盒。

3. 发明申请

WO2010019698A2 INHIBITION OF CALICIVIRUS (NOROVIRUS) 审中-公开
标题翻译：猕猴桃（NOROVIRUS）的抑制
公开(公告)号：WO2010019698A2
公开(公告)日：2010-02-18
申请号：PCT/US2009053591
申请日：2009-08-12
申请人： ENVIRGEN INC , CHANG KYEONG-OK , PARK HOSHIN , JOE IKRO
发明人： CHANG KYEONG-OK , PARK HOSHIN , JOE IKRO
IPC分类号： A61K38/21 , A61K31/05 , A61K31/5685 , A61K31/7056 , A61P31/12
CPC分类号： A61K38/212 , A61K31/05 , A61K31/56 , A61K31/7056 , A61K38/217 , A61K2300/00
摘要： The invention provides a method of treatment or prophylaxis of Calicivirus infection, comprising administering a pharmaceutical composition comprising a compound selected from the group of compounds consisting of interferon-alpha (IFN-a), interferon-gamma (IFN-?), honokiol, magnolol, ribavirin, z-guggulsterone, and a combination thereof and a pharmaceutically-acceptable carrier to a patient having a Calicivirus infection, or at risk for becoming infected with a Calicivirus.
摘要翻译：本发明提供了一种治疗或预防杯状病毒感染的方法，包括给予包含选自干扰素-α（IFN-α），干扰素-γ（IFN-α），厚朴酚，厚朴酚，利巴韦林，z-吉格斯酮及其组合，以及药学上可接受的载体，其具有杯状病毒感染或患有杯状病毒感染的风险。

4. 发明申请

WO2006098752A3 ULTRASENSITIVE SENSOR AND RAPID DETECTION OF ANALYTES 审中-公开
标题翻译：超声传感器和快速检测分析仪
公开(公告)号：WO2006098752A3
公开(公告)日：2009-04-16
申请号：PCT/US2005026806
申请日：2005-07-29
申请人： KIM LAB
发明人： KIM MYUNG L , JOE IKRO , PARK HOSHIN
IPC分类号： G01N33/48 , C12Q1/00
CPC分类号： B82Y5/00 , B82Y10/00 , G01N33/54373
摘要： The present invention relates to systems and methods for real time, rapid detection, identification, and enumeration of a wide variety of analytes, which include but are not limited to, cells (Eukarya, Eubacteria, Archaea), microorganisms, organelles, viruses, proteins (recombinant or natural proteins), nucleic acids, prionss, and any chemical, metabolites, or biological markers. The systems and methods, which include the laser/optic/electronic units, the analytic software, the assay methods and reagents, and the hight throughput automation, are particularly adapted to detection, identification, and enumeration of pathogens and non-pathogens in contaminated foods, clinical samples, and environmental samples. Other microorganisms that can be detected with the present invention include clinical pathogens, protozoa and, viruses.
摘要翻译：本发明涉及用于多种分析物的实时，快速检测，鉴定和计数的系统和方法，其包括但不限于细胞（真核细菌，真细菌，古细菌），微生物，细胞器，病毒，蛋白质（重组或天然蛋白），核酸，朊病毒和任何化学，代谢物或生物标记物。包括激光/光学/电子单元，分析软件，测定方法和试剂以及高通量自动化的系统和方法特别适用于污染食品中病原体和非病原体的检测，鉴定和计数，临床样本和环境样品。可用本发明检测的其它微生物包括临床病原体，原生动物和病毒。

5. 发明申请

WO2006098752A9 ULTRASENSITIVE SENSOR AND RAPID DETECTION OF ANALYTES 审中-公开
标题翻译：超声传感器和快速检测分析仪
公开(公告)号：WO2006098752A9
公开(公告)日：2007-03-15
申请号：PCT/US2005026806
申请日：2005-07-29
申请人： KIM LAB
发明人： KIM MYUNG L , JOE IKRO , PARK HOSHIN
IPC分类号： G06F19/00 , G06K9/00
CPC分类号： B82Y5/00 , B82Y10/00 , G01N33/54373
摘要： The present invention relates to systems and methods for real time, rapid detection, identification, and enumeration of a wide variety of analytes, which include but are not limited to, cells (Eukarya, Eubacteria, Archaea), microorganisms, organelles, viruses, proteins (recombinant or natural proteins), nucleic acids, prionss, and any chemical, metabolites, or biological markers. The systems and methods, which include the laser/optic/electronic units, the analytic software, the assay methods and reagents, and the hight throughput automation, are particularly adapted to detection, identification, and enumeration of pathogens and non-pathogens in contaminated foods, clinical samples, and environmental samples. Other microorganisms that can be detected with the present invention include clinical pathogens, protozoa and, viruses.
摘要翻译：本发明涉及用于多种分析物的实时，快速检测，鉴定和计数的系统和方法，其包括但不限于细胞（真核细菌，真细菌，古细菌），微生物，细胞器，病毒，蛋白质（重组或天然蛋白），核酸，朊病毒和任何化学，代谢物或生物标记物。包括激光/光学/电子单元，分析软件，测定方法和试剂以及高通量自动化的系统和方法特别适用于污染食品中病原体和非病原体的检测，鉴定和计数，临床样本和环境样品。可用本发明检测的其它微生物包括临床病原体，原生动物和病毒。

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