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1. 发明授权

US4359578A Naphthyridine derivatives and salts thereof useful as antibacterial agents 失效
标题翻译：萘吡啶衍生物及其盐可用作抗菌剂
公开(公告)号：US4359578A
公开(公告)日：1982-11-16
申请号：US68966
申请日：1979-08-23
申请人： Jun-ichi Matsumoto , Yoshiyuki Takase , Yoshiro Nishimura
发明人： Jun-ichi Matsumoto , Yoshiyuki Takase , Yoshiro Nishimura
IPC分类号： C07D213/74 , C07D213/75 , C07D213/77 , C07D471/04 , A61K31/495
CPC分类号： C07D213/74 , C07D213/75 , C07D213/77 , C07D471/04 , Y10S514/96 , Y10S514/962
摘要： This invention relates to 1,8-naphthyridine compounds of the formula ##STR1## wherein X is a halogen atom especially fluorine atom,R.sub.1 is an ethyl group or a vinyl group, andR.sub.2 is a hydrogen atom or a lower alkyl group, their salts and processes for the preparation of them.The 1,8-naphthyridine compounds and their salts are useful as antibacterial agents and intermediates thereof.

2. 发明授权

US4352803A Novel naphthyridine derivatives, intermediates thereof, processes for preparation thereof, and use thereof 失效
标题翻译：新型萘啶衍生物，其中间体，其制备方法及其用途
公开(公告)号：US4352803A
公开(公告)日：1982-10-05
申请号：US264824
申请日：1981-05-18
申请人： Jun-ichi Matsumoto , Yoshiyuki Takase , Yoshiro Nishimura
发明人： Jun-ichi Matsumoto , Yoshiyuki Takase , Yoshiro Nishimura
IPC分类号： C07D213/74 , C07D213/75 , C07D213/77 , C07D471/04 , A61K31/495
CPC分类号： C07D213/74 , C07D213/75 , C07D213/77 , C07D471/04 , Y10S514/96 , Y10S514/962
摘要： This invention relates to 1,8-naphthyridine compounds of the formula ##STR1## wherein X is a halogen atom especially fluorine atom,R.sub.1 is an ethyl group or a vinyl group, andR.sub.2 is a hydrogen atom or a lower alkyl group, their salts and processes for the preparation of them.The 1,8-naphthyridine compounds and their salts are useful as antibacterial agents and intermediates thereof.
摘要翻译：本发明涉及下式的1,8-萘啶化合物，其中X是卤原子，特别是氟原子，R 1是乙基或乙烯基，R 2是氢原子或低级烷基，它们的盐以及它们的制备过程。 1,8-萘啶化合物及其盐可用作抗菌剂及其中间体。

3. 发明授权

US4341784A Naphthyridine derivatives 失效
标题翻译：萘啶衍生物
公开(公告)号：US4341784A
公开(公告)日：1982-07-27
申请号：US187081
申请日：1980-09-15
申请人： Jun-ichi Matsumoto , Yoshiyuki Takase , Yoshiro Nishimura
发明人： Jun-ichi Matsumoto , Yoshiyuki Takase , Yoshiro Nishimura
IPC分类号： C07D487/02 , A61K31/435 , A61P31/04 , C07D471/04 , A61K31/44
CPC分类号： C07D471/04 , Y02P20/55
摘要： The present invention provides a 1,8-naphthyridine compound of the formula ##STR1## wherein R is hydrogen, methyl, ethyl or propyl, and a nontoxic pharmaceutically acceptable salt thereof, and a process for preparing a 1,8-naphthyridine compound of the above formula which comprises(A) reacting a compound of the formula ##STR2## wherein Y is halogen, lower alkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, lower alkylsulfonyloxy or arylsulfonyloxy, and R.sub.1 is hydrogen or lower alkyl,with a compound of the formula ##STR3## wherein R.sub.2 is hydrogen or a protective group for the amino group, and R is as defined above,and when a reaction product in which R.sub.1 is lower alkyl and/or R.sub.2 is the amino protective group is obtained, treating it with an acid or base, and/or reductively cleaving it,(B) decomposing a compound of the formula ##STR4## wherein A .crclbar. is a fluorine-containing anion, and R.sub.1 and R.sub.2 are as defined above,and when a reaction product in which R.sub.1 is lower alkyl and/or R.sub.2 is the amino protective group is obtained, treating it with an acid or base, and/or reductively cleaving it,(C) treating a compound of the formula ##STR5## wherein R'.sub.1 is hydrogen or lower alkyl, R'.sub.2 is hydrogen or a protective group for the amino group, provided that R'.sub.1 and R'.sub.2 are not hydrogen atoms at the same time, and R is as defined above,with an acid or base, and/or reductively cleaving it, and optionally converting the resulting compound to a nontoxic pharmaceutically acceptable salt thereof.The 1,8-naphthyridine compound is useful as an antibacterial agent.
摘要翻译：本发明提供式IMA图示的1,8-萘啶化合物，其中R是氢，甲基，乙基或丙基，及其无毒的药学上可接受的盐，以及制备1,8-萘啶化合物的方法其包含（A）使式（I）的化合物其中Y为卤素，低级烷氧基，低级烷硫基，低级烷基亚磺酰基，低级烷基磺酰基，低级烷基磺酰氧基或芳基磺酰氧基，R 1为氢或低级烷基，其中R2是氢或氨基保护基的式“IMAGE”，R的定义同上，当R1是低级烷基和/或R2是氨基保护基的反应产物得到时，将其处理（B）分解其中A（ - ）为含氟阴离子的式“IMAGE”的化合物，并且R 1和R 2如上所定义，当反应其中R1是低级烷基和/或 r R2是得到的氨基保护基团，用酸或碱处理，和/或还原性地裂解它;（C）处理下式化合物其中R'1是氢或低级烷基，R'2 是氢或氨基的保护基团，条件是R 1和R 2不同时为氢原子，R为如上所定义，与酸或碱反应，和/或还原性地裂解，和任选地将所得化合物转化为无毒的药学上可接受的盐。 1,8-萘啶化合物可用作抗菌剂。

4. 发明授权

US4017622A Piperazine derivatives 失效
标题翻译：哌嗪衍生物
公开(公告)号：US4017622A
公开(公告)日：1977-04-12
申请号：US545549
申请日：1975-01-30
申请人： Shinsaku Minami , Jun-Ichi Matsumoto , Minoru Sugita , Masanao Shimizu , Yoshiyuki Takase , Shinichi Nakamura
发明人： Shinsaku Minami , Jun-Ichi Matsumoto , Minoru Sugita , Masanao Shimizu , Yoshiyuki Takase , Shinichi Nakamura
IPC分类号： C07D215/56 , C07D401/04 , C07D471/04 , C07D295/10
CPC分类号： C07D401/04 , C07D215/56 , C07D471/04
摘要： Piperazine derivatives of the following formula ##STR1## wherein A and B are a carbon atom or a nitrogen atom except the case where both A and B are nitrogen atoms,R.sub.1 is hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a benzyl group or acetyl group;R.sub.2 is a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a benzyl group or a vinyl group; andR.sub.3 is hydrogen atom or an alkyl group having 1 to 6 carbon atoms, and pharmaceutically acceptable salts thereof.
摘要翻译：除了A和B都是氮原子，R1是氢原子，具有1至4个碳原子的烷基，苄基以外的其中A和B是碳原子或氮原子的下式的哌嗪衍生物，组或乙酰基; R2是氢原子，碳原子数1〜4的烷基，苄基或乙烯基; R3为氢原子或碳原子数为1〜6的烷基，及其药学上可接受的盐。

5. 发明授权

US3962443A Antibacterial pharmaceutical compositions and processes for preparation thereof 失效
标题翻译：抗菌药物组合物及其制备方法
公开(公告)号：US3962443A
公开(公告)日：1976-06-08
申请号：US551923
申请日：1975-02-21
申请人： Shinsaku Minami , Jun-ichi Matsumoto , Kazuyo Kawaguchi , Shinsaku Mishio , Masanao Shimizu , Yoshiyuki Takase , Shinichi Nakamura
发明人： Shinsaku Minami , Jun-ichi Matsumoto , Kazuyo Kawaguchi , Shinsaku Mishio , Masanao Shimizu , Yoshiyuki Takase , Shinichi Nakamura
IPC分类号： A61K31/505
摘要： This invention provides compounds of the following formula ##SPC1##Wherein R.sub.1 is a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a hydroxyalkyl group having 2 to 4 carbon atoms, a benzyl group, a benzyl group subsituted by methoxy, a phenyl group, a propargyl group or an acyl group; R.sub.2 is hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an alkyl group having 2 to 4 carbon atoms substituted by hydroxy or halogen, a vinyl group, an allyl group, or a benzyl group R.sub.3 is a hydrogen atom or an alkyl group having 1 to 6 carbon atoms;And salts thereof, and processes for preparing them. Some of the compounds have antibacterial activities.
摘要翻译：本发明提供下式的化合物，其中R 1是氢原子，具有1至4个碳原子的烷基，具有2至4个碳原子的羟基烷基，苄基，被甲氧基取代的苄基，苯基，炔丙基或酰基; R2为氢原子，碳原子数为1〜4的烷基，被羟基或卤素取代的碳原子数为2〜4的烷基，乙烯基，烯丙基或苄基R 3为氢原子或烷基具有1至6个碳原子的基团; 及其制备方法及其制备方法。一些化合物具有抗菌活性。

6. 发明授权

US07723615B2 Fluororesin composition and electric wire 有权
标题翻译：氟树脂组成和电线
公开(公告)号：US07723615B2
公开(公告)日：2010-05-25
申请号：US11920442
申请日：2006-05-17
申请人： Hideki Kono , Kenji Ishii , Yoshiyuki Takase , Sadashige Irie , Takahiro Kitahara
发明人： Hideki Kono , Kenji Ishii , Yoshiyuki Takase , Sadashige Irie , Takahiro Kitahara
IPC分类号： H01B7/00
CPC分类号： H01B3/445 , C08L27/18 , C08L2205/02 , C09D127/18 , C08L2666/04
摘要： A fluororesin composition including a tetrafluoroethylene/hexafluoropropylene-based copolymer and 0.01 to 3 parts by mass per 100 parts the copolymer of a polytetrafluoroethylene having a standard specific gravity of 2.15 to 2.30, and being obtained by mixing an aqueous dispersion of the tetrafluoroethylene/hexafluoropropylene-based copolymer with an aqueous dispersion of the polytetrafluoroethylene, causing coagulation, drying the polymer mixture and melt-extruding the same.
摘要翻译：包含四氟乙烯/六氟丙烯基共聚物的氟树脂组合物和每100份0.01至3质量份的标准比重为2.15至2.30的聚四氟乙烯的共聚物，通过将四氟乙烯/六氟丙烯基共聚物的水分散体，与聚四氟乙烯的水分散体共聚，引起凝结，干燥聚合物混合物并熔融挤出。

7. 发明申请

US20070112155A1 Process for production of fluorine-containing polymers and fluorine-containing polymers 有权
标题翻译：含氟聚合物和含氟聚合物的制备方法
公开(公告)号：US20070112155A1
公开(公告)日：2007-05-17
申请号：US10579790
申请日：2004-11-19
申请人： Yoshiyuki Takase , Kenji Ishii , Shouji Fukuoka
发明人： Yoshiyuki Takase , Kenji Ishii , Shouji Fukuoka
IPC分类号： C08F16/24
CPC分类号： C08F14/18 , C08F8/00 , C08F14/22 , C08F14/24 , C08F14/26 , C08F14/28 , C08F114/22 , C08F114/24 , Y10T428/3154
摘要： It is an object of the present invention to provide a method of producing a fluoropolymer high in terminal group stability and excellent in moldability. The present invention relates to a method of producing a fluoropolymer by which a melt-processable fluoropolymer (A) having a specific unstable terminal group or groups (P) is subjected to melt-kneading in a kneader comprising a stabilization treatment zone to thereby produce a fluoropolymer (B) resulting from conversion of said specific unstable terminal group or groups (P) to —CF2H, said specific unstable terminal group or groups (P) comprising alkoxycarbonyl groups, fluoroalkoxycarbonyl groups and/or carboxyl group quaternary nitrogen compound salts, the melt-kneading being carried out in the absence or presence of an alkali metal element or alkaline earth metal element, the mass of said alkali metal element or alkaline earth metal element being not greater than 2 ppm of the composition under melt-kneading, and the melt-kneading in said stabilization treatment zone being carried out in the presence of water.
摘要翻译：本发明的目的是提供一种制备端基稳定性高，成型性优异的含氟聚合物的方法。本发明涉及一种含氟聚合物的制造方法，其中将具有特定不稳定末端基的可熔融加工的含氟聚合物（A）或基团（P）在包含稳定化处理区域的捏和机中进行熔融捏合，从而产生所述特定的不稳定末端基团（P）转化为-CF 2 H所得的含氟聚合物（B），所述特定的不稳定末端基团（P）或包含烷氧基羰基的基团（P），氟代烷氧基羰基和/或羧基季氮化合物盐，在不存在或存在碱金属元素或碱土金属元素的情况下进行熔融捏合，所述碱金属元素或碱土金属元素的质量不大于在熔融捏合下的组合物和在所述稳定化处理区域中的熔融捏合在水的存在下进行。

8. 发明授权

US08080195B2 Process for production of fluorine-containing polymers and fluorine-containing polymers 有权
标题翻译：含氟聚合物和含氟聚合物的制备方法
公开(公告)号：US08080195B2
公开(公告)日：2011-12-20
申请号：US10579790
申请日：2004-11-19
申请人： Yoshiyuki Takase , Kenji Ishii , Shouji Fukuoka
发明人： Yoshiyuki Takase , Kenji Ishii , Shouji Fukuoka
IPC分类号： B27N3/08
CPC分类号： C08F14/18 , C08F8/00 , C08F14/22 , C08F14/24 , C08F14/26 , C08F14/28 , C08F114/22 , C08F114/24 , Y10T428/3154
摘要： A method of producing a fluoropolymer by which a melt-processable fluoropolymer (A) having a specific unstable terminal group or groups (P) is subjected to melt-kneading in a kneader having a stabilization treatment zone to thereby produce a fluoro-polymer (B) resulting from conversion of the specific unstable terminal group or groups (P) to —CF2H. The specific unstable terminal group or groups (P) include alkoxycarbonyl groups, fluoroalkoxycarbonyl groups and/or carboxyl group quaternary nitrogen compound salts, the melt-kneading is carried out in the absence or presence of an alkali metal element or alkaline earth metal element, the content of the alkali metal element or alkaline earth metal element is not greater than 2 ppm of the composition under melt-kneading, and the melt-kneading in the stabilization treatment zone is carried out in the presence of water. A fluoro-polymerised material is also disclosed.
摘要翻译：在具有稳定化处理区域的捏合机中对具有特定不稳定末端基团（P）的可熔融加工的含氟聚合物（A）进行熔融混炼的含氟聚合物的制造方法，由此制造氟聚合物）由特定的不稳定末端基团（P）转化为-CF 2 H而得到。特定的不稳定末端基（P）包括烷氧基羰基，氟代烷氧基羰基和/或羧基季氮化合物盐，在不存在或不存在碱金属元素或碱土金属元素的情况下进行熔融混炼，在熔融捏合下，碱金属元素或碱土金属元素的含量不超过组合物的2ppm，稳定化处理区的熔融捏合在水的存在下进行。还公开了氟聚合材料。

9. 发明授权

US07724451B2 Lens assembly and imaging device 有权
标题翻译：镜头组件和成像装置
公开(公告)号：US07724451B2
公开(公告)日：2010-05-25
申请号：US12016002
申请日：2008-01-17
申请人： Yoshiyuki Takase
发明人： Yoshiyuki Takase
IPC分类号： G02B7/02
CPC分类号： G02B7/026 , G02B7/021 , H04N5/2254
摘要： A lens assembly includes: a lens group including a plurality of lenses; and a lens holder accommodating the lens group and having an opening in each of a front end face of the lens holder and a rear end face of the lens holder. The opening of the front end face has a smaller diameter than an outer diameter of a foremost lens accommodated in a foremost end face side of the lens holder, the lens holder includes a spacer ring disposed on a rear side of a rearmost lens accommodated in a rearmost end face side of the lens holder, the spacer ring abutting on a peripheral portion of the rearmost lens to keep a space between a rear face of the rearmost lens and the rear end face of the lens holder, and the lens holder holds a rear face of the spacer ring by thermal caulking.
摘要翻译：透镜组件包括：包括多个透镜的透镜组; 以及容纳透镜组并且在透镜保持件的前端面和透镜保持件的后端面中的每一个中具有开口的透镜架。前端面的开口部具有比容纳在透镜保持件的最前端面侧的最前端的透镜的外径小的透镜保持架，该透镜保持架具有配置在最后部透镜的背面侧的间隔环，隔离环抵靠在最后面的透镜的周边部分上，以保持最后面的透镜的后表面和透镜保持器的后端面之间的空间，并且透镜保持器保持后部通过热铆接的间隔环的表面。

10. 发明授权

US07604861B2 Fluororesin composition, process for preparing the same and cable coated with the same 有权
标题翻译：氟树脂组合物，其制备方法和用其涂覆的电缆
公开(公告)号：US07604861B2
公开(公告)日：2009-10-20
申请号：US11640281
申请日：2006-12-18
申请人： Masayuki Namimatsu , Yoshiyuki Hiraga , Yoshiyuki Takase , Tadahiro Yabu
发明人： Masayuki Namimatsu , Yoshiyuki Hiraga , Yoshiyuki Takase , Tadahiro Yabu
IPC分类号： B32B15/02 , H01B7/00 , B32B15/08
CPC分类号： H01B3/445 , C08L27/18 , C08L2205/02 , C09D127/18 , Y10T428/249953 , Y10T428/2933 , Y10T428/294 , Y10T428/3154 , Y10T428/31544 , Y10T428/31678 , C08L2666/04
摘要： The present invention provides a fluororesin composition, which is excellent in moldability and crack resistance, a process for preparing the composition and a cable evenly coated with the composition. Specifically, the present invention provides a fluororesin composition wherein polytetrafluoroethylene is compounded to a terpolymer comprising tetrafluoroethylene, hexafluoropropylene and perfluoroalkyl vinylether. Also, the present invention provides a process for preparing the composition which comprises kneading with a multi-screw kneader. Furthermore, the present invention provides a cable which is coated with the resin.
摘要翻译：本发明提供了一种成型性和抗龟裂性优异的氟树脂组合物，制备该组合物的方法和均匀涂覆该组合物的电缆。具体地说，本发明提供一种氟树脂组合物，其中聚四氟乙烯与包含四氟乙烯，六氟丙烯和全氟烷基乙烯基醚的三元共聚物配混。此外，本发明提供了一种制备组合物的方法，其包括用多螺杆混炼机捏合。此外，本发明提供了涂覆有树脂的电缆。

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