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1. 发明申请

US20110046538A1 COMBINATION OF A LIGHT RAY WITH A CYTOCHROME C OXIDASE SUBSTRATE PARTICULARLY FOR IMPROVING THE APPEARANCE OF THE SKIN AND/OR HAIR 有权
标题翻译：光照与细胞色素C氧化物底物的组合特别用于改善皮肤和/或头发的外观
公开(公告)号：US20110046538A1
公开(公告)日：2011-02-24
申请号：US12866575
申请日：2009-02-06
申请人： Julien Laboureau , Quang Lan Nguyen , Dang-Man Pham
发明人： Julien Laboureau , Quang Lan Nguyen , Dang-Man Pham
IPC分类号： A61N5/06 , A61K38/16 , A61Q19/00 , A61Q5/00
CPC分类号： A61K41/00 , A61K8/19 , A61K8/494 , A61K8/66 , A61K38/1709 , A61K45/06 , A61K2800/81 , A61K2800/92 , A61N5/0617 , A61Q7/00 , A61Q19/007 , A61Q19/02 , A61Q19/08 , C12Y109/03001
摘要： The invention relates to the combination of a light ray with a cytochrome C oxydase substrate particularly for improving the appearance of the skin and/or the hair. The invention more particularly relates to a method for a cosmetic treatment particularly for improving the appearance of the skin and/or the hair that comprises the simultaneous and/or sequential administration of a) at least one cytochrome C oxydase substrate and/or at least one agent increasing the expression of said substrate; and b) at least one light radiation having at least one predominant wavelength that activates the cytochrome C oxydase. More particularly, said light radiation has at least one predominant wavelength activating the cytochrome C oxydase, that ranges from 550 to 1000 nm, in particular from 550 to 800 nm, preferably from 620 to 700 nm, and more preferably from 640 to 680 nm; the method comprises applying a dose preferably ranging from 0.01 to 200 J/cm2, preferably from 0.1 to 30 J/cm2, more preferably from 1 to 30 J/cm2, or even from 5 to 30 J/cm2. The invention also relates to a composition containing at least one cytochrome C oxydase substrate and/or one agent increasing the expression of said substrate, and at least one compound emitting and/or filtering, in particular under light exposure, a light radiation having at least one predominant wavelength that activates the cytochrome C oxydase. The invention also relates to a kit including at least one composition containing at least one cytochrome C oxydase substrate and/or one agent increasing the expression of said substrate, and at least one device and/or compound emitting and/or filtering a light radiation having at least one predominant wavelength that activates the cytochrome C oxydase.
摘要翻译：本发明涉及光线与细胞色素C氧化酶底物的组合，特别是用于改善皮肤和/或毛发的外观。本发明更具体涉及用于特别用于改善皮肤和/或毛发外观的化妆品处理方法，其包括同时和/或顺序施用a）至少一种细胞色素C氧化酶底物和/或至少一种增加所述底物的表达; 和b）至少一种具有至少一种主要波长的光辐射，其激活细胞色素C氧化酶。更具体地说，所述光辐射具有激活细胞色素C氧化酶的至少一种主要波长，其范围为550至1000nm，特别是550至800nm，优选620至700nm，更优选640至680nm; 该方法包括施加0.01〜200J / cm 2，优选为0.1〜30J / cm 2，更优选为1〜30J / cm 2，或甚至5〜30J / cm 2的剂量。本发明还涉及包含至少一种细胞色素C氧化酶底物和/或增加所述底物表达的一种试剂的组合物，以及至少一种特别是在光照下发射和/或过滤具有至少一种主要的波长激活细胞色素C氧化酶。本发明还涉及一种试剂盒，其包含至少一种含有至少一种细胞色素C氧化酶底物和/或增加所述底物表达的试剂的组合物，以及至少一种发射和/或过滤具有活化细胞色素C氧化酶的至少一种主要波长。

2. 发明授权

US09119798B2 Combination of a light ray with a cytochrome C oxidase substrate particularly for improving the appearance of the skin and/or hair 有权
标题翻译：光线与细胞色素C氧化酶底物的组合，特别是用于改善皮肤和/或头发的外观
公开(公告)号：US09119798B2
公开(公告)日：2015-09-01
申请号：US12866575
申请日：2009-02-06
申请人： Julien Laboureau , Quang Lan Nguyen , Dang-Man Pham
发明人： Julien Laboureau , Quang Lan Nguyen , Dang-Man Pham
IPC分类号： A61K8/66 , A61N5/06 , A61K8/19 , A61K8/49 , A61Q7/00 , A61Q19/00 , A61Q19/02 , A61Q19/08
CPC分类号： A61K41/00 , A61K8/19 , A61K8/494 , A61K8/66 , A61K38/1709 , A61K45/06 , A61K2800/81 , A61K2800/92 , A61N5/0617 , A61Q7/00 , A61Q19/007 , A61Q19/02 , A61Q19/08 , C12Y109/03001
摘要： The invention relates to the combination of a light ray with a cytochrome C oxidase substrate for improving the appearance of the skin and/or the hair.
摘要翻译：本发明涉及光线与细胞色素C氧化酶底物的组合，用于改善皮肤和/或头发的外观。

3. 发明授权

US09750675B2 Use of green light to activate L-amino acid oxidase 有权
公开(公告)号：US09750675B2
公开(公告)日：2017-09-05
申请号：US12668689
申请日：2008-07-16
申请人： Julien Laboureau , Quang Lan Nguyen
发明人： Julien Laboureau , Quang Lan Nguyen
IPC分类号： A61K8/44 , A61K8/49 , A61K8/67 , A61Q19/08 , A61N5/06 , A61N5/067
CPC分类号： A61K8/44 , A61K8/442 , A61K8/447 , A61K8/4953 , A61K8/4973 , A61K8/673 , A61K2800/78 , A61K2800/81 , A61N5/0616 , A61N5/0617 , A61N2005/0652 , A61N2005/0654 , A61N2005/067 , A61Q19/08
摘要： The present invention relates to the use of a source of green light for activating L-amino acid oxidase in the presence of at least one substrate of this enzyme in order to stimulate the energy metabolism of the cells of the skin, to stimulate their replacement and thus to improve the appearance of the skin and hair, in particular to prevent and/or treat cutaneous signs of ageing of the skin and hair.

4. 发明申请

US20100228181A1 USE OF GREEN LIGHT TO ACTIVATE L-AMINO ACID OXIDASE 有权
标题翻译：使用绿光激活L-氨基酸氧化酶
公开(公告)号：US20100228181A1
公开(公告)日：2010-09-09
申请号：US12668689
申请日：2008-07-16
申请人： Julien Laboureau , Quang Lan Nguyen
发明人： Julien Laboureau , Quang Lan Nguyen
IPC分类号： A61M37/00 , A61K8/67 , A61K8/49 , A61Q19/08
CPC分类号： A61K8/44 , A61K8/442 , A61K8/447 , A61K8/4953 , A61K8/4973 , A61K8/673 , A61K2800/78 , A61K2800/81 , A61N5/0616 , A61N5/0617 , A61N2005/0652 , A61N2005/0654 , A61N2005/067 , A61Q19/08
摘要： The present invention relates more specifically to the use of a source of green light for activating L-amino acid oxidase in the presence of at least one substrate of this enzyme in order to stimulate the energy metabolism of the cells of the skin, to stimulate their replacement and thus to improve the appearance of the skin and hair, in particular to prevent and/or treat cutaneous signs of ageing of the skin and hair.The invention also relates to a composition comprising at least one substrate of the enzyme and at least one substrate capable of emitting green light, to a kit comprising a green light device and the composition comprising at least one substrate of the said enzyme and to a cosmetic method employing the compositions or kits according to the invention.
摘要翻译：本发明更具体地涉及绿光源用于在该酶的至少一个底物存在下活化L-氨基酸氧化酶的用途，以刺激皮肤细胞的能量代谢，以刺激它们从而改善皮肤和头发的外观，特别是防止和/或治疗皮肤和头发的皮肤老化迹象。本发明还涉及一种组合物，其包含至少一种酶底物和至少一种能够发出绿光的底物，包含绿光装置的试剂盒和包含所述酶的至少一个底物的组合物和化妆品采用本发明的组合物或试剂盒的方法。

5. 发明授权

US09364411B2 Use of monosaccharides and composition therefor 有权
标题翻译：使用单糖及其组合物
公开(公告)号：US09364411B2
公开(公告)日：2016-06-14
申请号：US12648485
申请日：2009-12-29
申请人： Jean-Thierry Simonnet , Julien Laboureau , Pascal Portes , Christophe Boulle
发明人： Jean-Thierry Simonnet , Julien Laboureau , Pascal Portes , Christophe Boulle
IPC分类号： A61K31/7004 , C07H1/00 , A61K8/60 , A61K8/02 , A61Q5/12 , A61Q7/00 , A61Q19/08
CPC分类号： A61K8/60 , A61K8/02 , A61K2800/91 , A61Q5/12 , A61Q7/00 , A61Q19/08
摘要： The present invention relates to the use, especially the cosmetic use, of at least one monosaccharide chosen from mannose, rhamnose and a mixture thereof, for reducing or preventing the signs of ageing of the skin or its integuments. The present invention also relates to a cosmetic composition and a device containing it.
摘要翻译：本发明涉及至少一种选自甘露糖，鼠李糖及其混合物的单糖的用途，特别是化妆品用途，用于减少或预防皮肤或其皮肤老化的迹象。本发明还涉及一种化妆品组合物和含有它的装置。

6. 发明申请

US20100190727A1 USE OF MONOSACCHARIDES AND COMPOSITION THEREFOR 有权
标题翻译：单一化合物的使用及其组合物
公开(公告)号：US20100190727A1
公开(公告)日：2010-07-29
申请号：US12648485
申请日：2009-12-29
申请人： Jean-Thierry SIMONNET , Julien Laboureau , Pascal Portes , Christophe Boulle
发明人： Jean-Thierry SIMONNET , Julien Laboureau , Pascal Portes , Christophe Boulle
IPC分类号： A61K31/7004 , C07H1/00
CPC分类号： A61K8/60 , A61K8/02 , A61K2800/91 , A61Q5/12 , A61Q7/00 , A61Q19/08
摘要： The present invention relates to the use, especially the cosmetic use, of at least one monosaccharide chosen from mannose, rhamnose and a mixture thereof, for reducing or preventing the signs of ageing of the skin or its integuments. The present invention also relates to a cosmetic composition and a device containing it.
摘要翻译：本发明涉及至少一种选自甘露糖，鼠李糖及其混合物的单糖的用途，特别是化妆品用途，用于减少或预防皮肤或其皮肤老化的迹象。本发明还涉及一种化妆品组合物和含有它的装置。

7. 发明授权

US08445459B2 Combination of monosaccharide with C-glycoside derivative and use thereof 有权
标题翻译：单糖与C-糖苷衍生物的组合及其用途
公开(公告)号：US08445459B2
公开(公告)日：2013-05-21
申请号：US12649366
申请日：2009-12-30
申请人： Julien Laboureau , Jean-Thierry Simonnet , Pascal Portes
发明人： Julien Laboureau , Jean-Thierry Simonnet , Pascal Portes
IPC分类号： A61K8/60 , A61Q19/00
CPC分类号： A61K8/60 , A61K8/06 , A61K8/062 , A61K8/602 , A61K2800/592 , A61Q19/08
摘要： Composition, especially a cosmetic and/or dermatological composition, containing, in a physiologically acceptable medium, at least one of mannose, and rhamnose and at least one additional compound chosen from C-glycosides and C-glycoside derivatives. Use of such a composition, and also a device containing it.
摘要翻译：组合物，特别是化妆品和/或皮肤病学组合物，其在生理学上可接受的培养基中包含甘露糖和鼠李糖中的至少一种和至少一种选自C-糖苷和C-糖苷衍生物的另外的化合物。使用这样的组合物，以及含有它的装置。

8. 发明申请

US20090285770A1 Topical Compositions for Promoting Homeostasis of the Skin 审中-公开
标题翻译：促进皮肤稳态的专题组合
公开(公告)号：US20090285770A1
公开(公告)日：2009-11-19
申请号：US12085228
申请日：2006-11-17
申请人： Julien Laboureau
发明人： Julien Laboureau
IPC分类号： A61K31/74 , A61K38/02 , A61P17/00 , A61K38/39 , A61K31/315 , A61K31/28 , A61K31/785 , A61K31/78 , A61Q19/00
CPC分类号： A61K8/8152 , A61K8/25 , A61K8/365 , A61K8/60 , A61K8/64 , A61K8/73 , A61K8/8158 , A61K2800/70 , A61Q19/00 , A61Q19/08
摘要： The invention relates in particular to a composition for topical application to the skin, comprising, in a physiologically acceptable medium, at least one peptide increasing the expression of mechanoreceptors in the cells of the skin and at least one tensing agent. According to one alternative the agent increasing the expression of mechanoreceptors in the cells of the skin is selected from zinc salts, copper salts, manganese salts, derivatives thereof and mixtures thereof. The invention likewise relates to a skincare kit comprising at least two compositions comprising respectively the tensing agent and the agent increasing the expression of mechanoreceptors in the cells of the skin. The invention also relates to a method of cosmetic treatment of the skin that comprises simultaneous or sequential application of said compositions.
摘要翻译：本发明特别涉及用于局部应用于皮肤的组合物，其在生理上可接受的培养基中包含增加皮肤细胞中的机械感受器表达的至少一种肽和至少一种张力剂。根据一个替代方案，增加皮肤细胞中机械感受器表达的试剂选自锌盐，铜盐，锰盐，其衍生物及其混合物。本发明同样涉及护肤试剂盒，其包含至少两种组合物，其分别包含增加皮肤细胞中机械感受器表达的张力剂和药剂。本发明还涉及包含同时或顺序施用所述组合物的皮肤美容治疗方法。

9. 发明授权

US09974984B2 Combination of monosaccharides with antioxidants and use thereof 有权
公开(公告)号：US09974984B2
公开(公告)日：2018-05-22
申请号：US12649368
申请日：2009-12-30
申请人： Julien Laboureau , Jean-Thierry Simonnet , Pascal Portes , Karine Lucet-Levannier
发明人： Julien Laboureau , Jean-Thierry Simonnet , Pascal Portes , Karine Lucet-Levannier
IPC分类号： A61K36/00 , A61Q19/08 , A61K8/34 , A61K8/365 , A61K8/44 , A61K8/49 , A61K8/60 , A61K8/67 , A61K8/97
CPC分类号： A61Q19/08 , A61K8/347 , A61K8/365 , A61K8/44 , A61K8/498 , A61K8/60 , A61K8/678 , A61K8/97 , A61K2800/522
摘要： The present invention relates to a composition, especially a cosmetic and/or dermatological composition, containing, in a physiologically acceptable medium, a combination of at least one monosaccharide chosen from mannose, rhamnose and a mixture thereof, and of at least one antioxidant. The present invention also relates to the use of such a composition.

10. 发明授权

US09132075B2 Combination of monosaccharides with ascorbic acid and use thereof 有权
标题翻译：单糖与抗坏血酸的组合及其用途
公开(公告)号：US09132075B2
公开(公告)日：2015-09-15
申请号：US12649370
申请日：2009-12-30
申请人： Julien Laboureau , Jean-Thierry Simonnet , Pascal Portes
发明人： Julien Laboureau , Jean-Thierry Simonnet , Pascal Portes
IPC分类号： A61K8/60 , A61Q19/00 , A61Q19/08 , A61K8/67
CPC分类号： A61K8/676 , A61K8/60 , A61K2800/592 , A61K2800/91 , A61Q19/08
摘要： Composition containing a combination of at least one monosaccharide chosen from mannose, rhamnose and a mixture thereof, and of at least one additional compound chosen from ascorbic acid, an analogue thereof and a mixture thereof. The present invention also relates to the use of such a composition for combating the signs of ageing, and also to a device containing the composition.
摘要翻译：含有至少一种选自甘露糖，鼠李糖及其混合物的单糖以及选自抗坏血酸，其类似物及其混合物的至少一种另外的化合物的组合的组合物。本发明还涉及这种组合物用于防止老化迹象的用途，以及含有该组合物的装置。

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