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1. 发明申请

US20070202050A1 Pharmaceutical Formulations 审中-公开
标题翻译：药物制剂
公开(公告)号：US20070202050A1
公开(公告)日：2007-08-30
申请号：US11672413
申请日：2007-02-07
申请人： Julianne Berry , Saeed Chaudhry , Joel Sequeira , Lukeysha Kline , Susan D'Souza
发明人： Julianne Berry , Saeed Chaudhry , Joel Sequeira , Lukeysha Kline , Susan D'Souza
IPC分类号： A61K9/12 , A61K31/4245 , A61K31/573 , A61K31/7034 , A61K31/65
CPC分类号： A61K9/008 , A61K9/0043 , A61K31/4245 , A61K31/573 , A61K31/65 , A61K31/7034 , A61K47/14 , Y02A50/465
摘要： An aspect of the present invention provides for a medicament including a solution containing pleconaril or a pharmaceutically acceptable salt thereof, wherein at least one solvent comprising said solution is a pleconaril-dissolving glyceride oil, and the solution is suitable for inhalation administration as an aerosol mist.
摘要翻译：本发明的一个方面提供了一种药物，其包含含有pleconaril或其药学上可接受的盐的溶液，其中至少一种包含所述溶液的溶剂是溶解于溶剂的甘油酯油，并且该溶液适合作为气雾剂的吸入给药。

2. 发明申请

US20070202055A1 Pharmaceutical Formulations 审中-公开
标题翻译：药物制剂
公开(公告)号：US20070202055A1
公开(公告)日：2007-08-30
申请号：US11672408
申请日：2007-02-07
申请人： Julianne Berry , Saeed Chaudhry , Joel Sequeira , Lukeysha Kline , Susan D'Souza
发明人： Julianne Berry , Saeed Chaudhry , Joel Sequeira , Lukeysha Kline , Susan D'Souza
IPC分类号： A61K9/14 , A61K31/7048 , A61K31/7034 , A61K31/573 , A61K31/616 , A61K31/192 , A61K31/19
CPC分类号： A61K9/0043 , A61K9/0073
摘要： An aspect of the present invention provides for a medicament suitable for administration as a nasal inhalant including an aqueous carrier and suspended therein particulate pleconaril, the aqueous carrier including a thixotropic composition including microcrystalline cellulose and a polymer selected from an alkali metal carboxyalkylcellulose, a polyvinylpyrrolidone polymer, and mixtures thereof.
摘要翻译：本发明的一个方面提供了一种药物，其适用于作为包含水性载体的鼻吸入剂并且悬浮在其中的颗粒pleconaril的鼻吸入剂，所述水性载体包括触变组合物，包括微晶纤维素和选自碱金属羧烷基纤维素，聚乙烯吡咯烷酮聚合物，及其混合物。

3. 发明申请

US20080064674A1 Pharmaceutical Compositions 审中-公开
标题翻译：药物组合物
公开(公告)号：US20080064674A1
公开(公告)日：2008-03-13
申请号：US11940046
申请日：2007-11-14
申请人： Julianne Berry , Jill Sherwood , Saeed Chaudhry , Joel Sequeira
发明人： Julianne Berry , Jill Sherwood , Saeed Chaudhry , Joel Sequeira
IPC分类号： A61K31/56 , A61M11/00
CPC分类号： A61K9/008 , A61K9/12 , A61K9/124 , A61K31/58 , A61K2300/00
摘要： Disclosed are metered dose inhalers having a metering valve to deliver a dose containing an aerosol suspension formulation, said aerosol suspension formulation comprising: an effective amount of Mometasone Furoate, Formoterol or a combination thereof; a suspension medium selected from the group consisting of 1,1,1,2,3,3,3,-heptafluoropropane, 1,1,1,2-tetrafluoroethane; and a solvent that is ethanol; wherein said formulation contains less than about 500 μg of non-volatile residue as measured by ultraviolet spectroscopy.
摘要翻译：公开了具有计量阀以计量含有气溶胶悬浮液制剂的计量剂量吸入器，所述气溶胶悬浮液制剂包含：有效量的糠酸莫米松，福莫特罗或其组合; 选自1,1,1,2,3,3,3， - 七氟丙烷，1,1,1,2-四氟乙烷的悬浮介质; 和乙醇的溶剂; 其中所述制剂含有通过紫外光谱测量的小于约500杯非挥发性残余物。

4. 发明申请

US20070203104A1 Pharmaceutical Formulations 审中-公开
标题翻译：药物制剂
公开(公告)号：US20070203104A1
公开(公告)日：2007-08-30
申请号：US11672400
申请日：2007-02-07
申请人： Saeed Chaudhry , Julianne Berry , Joel Sequeira
发明人： Saeed Chaudhry , Julianne Berry , Joel Sequeira
IPC分类号： A61K31/573 , A61K31/4245 , A61K31/4164 , A61K31/137
CPC分类号： A61K9/008 , A61K31/137 , A61K31/4164 , A61K31/4245 , A61K31/573 , A61K47/34 , Y02A50/465
摘要： An aspect of the present invention provides for a medicament including a solution containing pleconaril or a pharmaceutically acceptable salt thereof, wherein at least one solvent including the solution is a pleconaril-dissolving hydrofluorocarbon.
摘要翻译：本发明的一个方面提供了一种药物，其包含含有pleconaril或其药学上可接受的盐的溶液，其中至少一种包括溶液的溶剂是溶解于溶剂的氢氟烃。

5. 发明申请

US20080066744A1 PROCESS FOR PRODUCING METERED DOSE INHALER FORMULATIONS 审中-公开
标题翻译：生产计量剂量吸入剂制剂的方法
公开(公告)号：US20080066744A1
公开(公告)日：2008-03-20
申请号：US11948688
申请日：2007-11-30
申请人： Saeed Chaudhry , Stefan Sharpe , Julianne Berry , Joel Sequeira
发明人： Saeed Chaudhry , Stefan Sharpe , Julianne Berry , Joel Sequeira
IPC分类号： A61M11/04 , A61K9/14
CPC分类号： B65B3/003 , A61M11/04 , A61M15/0065 , B65B31/003
摘要： Disclosed are methods of introducing a suspension or solution of a medicament, preferably mometasone furoate anhydrous, into a metered dose inhaler container, said container having a valve attached thereto, said method comprising the steps of introducing mometasone furoate anhydrous, a surfactant and a chlorofluorocarbon free propellant into a vessel that is held under pressure to form a suspension or solution, circulating said suspension or solution from the vessel through a line which includes a filling head, bringing said filling head into communication with said metered dose inhaler container through said valve of said metered dose inhaler container, introducing a quantity of such suspension or solution into the container from the filling head of the line through said valve of said metered dose inhaler container, withdrawing said filling head from said metered dose inhaler container, and sealing said metered dose inhaler container, as well as the products produced thereby having an improved particle size distribution of the active ingredients in metered dose inhalers.
摘要翻译：公开了将药物，优选无糠酸莫米他松无水物质的悬浮液或溶液引入计量吸入器容器中的方法，所述容器具有附着于其上的阀，所述方法包括以下步骤：将无糠酸莫米松，无表面活性剂和不含氯氟烃的引入推进剂进入保持在压力下以形成悬浮液或溶液的容器中，使来自容器的悬浮液或溶液通过包括填充头的管线循环，使所述填充头与所述计量剂量吸入器容器连通，通过所述阀计量吸入器容器，通过所述计量吸入器容器的所述阀从管线的填充头将一定数量的这种悬浮液或溶液引入容器中，从所述计量吸入器容器中取出所述填充头，并密封所述计量剂量吸入器集装箱，以及由此生产的产品改进计量吸入器中活性成分的粒度分布。

6. 发明申请

US20050136009A1 Pharmaceutical compositions 审中-公开
标题翻译：药物组合物
公开(公告)号：US20050136009A1
公开(公告)日：2005-06-23
申请号：US10967719
申请日：2004-10-18
申请人： Julianne Berry , Jill Sherwood , Saeed Chaudhry , Joel Sequeira
发明人： Julianne Berry , Jill Sherwood , Saeed Chaudhry , Joel Sequeira
IPC分类号： A61K9/00 , A61K9/12 , A61K9/14 , A61K31/58 , A61L9/04 , A61M11/00
CPC分类号： A61K9/008 , A61K9/12 , A61K9/124 , A61K31/58 , A61K2300/00
摘要： Disclosed are metered dose inhalers having a metering valve to deliver a dose containing an aerosol suspension formulation, said aerosol suspension formulation comprising: an effective amount of Mometasone Furoate, Formoterol or a combination thereof; a suspension medium selected from the group consisting of 1,1,1,2,3,3,3,-heptafluoropropane, 1,1,1,2-tetrafluoroethane; and a solvent that is ethanol; wherein said formulation contains less than about 500 μg of non-volatile residue as measured by ultraviolet spectroscopy.
摘要翻译：公开了具有计量阀以计量含有气溶胶悬浮液制剂的计量剂量吸入器，所述气溶胶悬浮液制剂包含：有效量的糠酸莫米松，福莫特罗或其组合; 选自1,1,1,2,3,3,3， - 七氟丙烷，1,1,1,2-四氟乙烷的悬浮介质; 和乙醇的溶剂; 其中所述制剂含有通过紫外光谱测量的小于约500杯非挥发性残余物。

7. 发明申请

US20130068218A1 PROCESS FOR PRODUCING METERED DOSE INHALER FORMULATIONS 审中-公开
标题翻译：生产计量剂量吸入剂制剂的方法
公开(公告)号：US20130068218A1
公开(公告)日：2013-03-21
申请号：US13592899
申请日：2012-08-23
申请人： Saeed Chaudhry , Stefan A. Sharpe , Julianne Berry , Joel A. Sequeira
发明人： Saeed Chaudhry , Stefan A. Sharpe , Julianne Berry , Joel A. Sequeira
IPC分类号： B65B3/00 , A61M15/00 , A61M11/04
CPC分类号： B65B3/003 , A61M11/04 , A61M15/0065 , B65B31/003
摘要： Disclosed are methods of introducing a suspension or solution of a medicament, preferably mometasone furoate anhydrous, into a metered dose inhaler container.
摘要翻译：公开了将药物，优选无糠酸莫米他松的悬浮液或溶液引入计量剂量吸入器容器中的方法。

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